Abstract:
:General anesthesia is a man-made neurophysiological state comprised of unconsciousness, amnesia, analgesia, and immobility along with maintenance of physiological stability. Growing evidence suggests that anesthetic-induced neural oscillations are a primary mechanism of anesthetic action. Each anesthetic drug class produces distinct oscillatory dynamics that can be related to the circuit mechanisms of drug action. Sleep is a naturally occurring state of decreased arousal that is essential for normal health. Physiological measurements (electrooculogram, electromyogram) and neural oscillatory (electroencephalogram) dynamics are used to empirically characterize sleep into rapid eye movement sleep and the three stages of non-rapid eye movement sleep. In this review, we discuss the differences between anesthesia- and sleep-induced altered states from the perspective of neural oscillations.
journal_name
Curr Opin Neurobioljournal_title
Current opinion in neurobiologyauthors
Akeju O,Brown ENdoi
10.1016/j.conb.2017.04.011subject
Has Abstractpub_date
2017-06-01 00:00:00pages
178-185eissn
0959-4388issn
1873-6882pii
S0959-4388(17)30043-0journal_volume
44pub_type
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