Abstract：
:Cognitive neuroimaging maps the brain locations of mental operations. This process is iterative, as no single study can fully characterize a mental operation or its brain location. This iterative discovery process, in combination with the location-reporting standard (i.e. spatial coordinates) of the cognitive neuroimaging community, has engendered a new form of metanalysis. Response locations from multiple studies have been analyzed collectively so as to better describe the spatial distribution of brain activations, with promising results. New hypotheses regarding elementary mental operations and their respective brain locations are being generated and refined via metanalysis. These hypotheses are being tested and confirmed by subsequent, prospective experiments. Function/location metanalysis is an important new tool for hypothesis generation in cognitive neuroimaging. This form of metanalysis is fundamentally different from the effect-size metanalyses prevalent in other literatures, with unique advantages and challenges.
journal_name
Curr Opin Neurobioljournal_title
Current opinion in neurobiologyauthors
Fox PT,Parsons LM,Lancaster JLdoi
10.1016/s0959-4388(98)80138-4subject
Has Abstractpub_date
1998-04-01 00:00:00pages
178-87issue
2eissn
0959-4388issn
1873-6882pii
S0959-4388(98)80138-4journal_volume
8pub_type
杂志文章,评审abstract：:The recent cloning of the gamma-aminobutyric acid and norepinephrine Na(+)-dependent neurotransmitter transporters has led to new approaches for understanding the structure and function of these important synaptic proteins and provides a conceptual model in which to consider recent advances in the physiology, pharmaco...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/0959-4388(91)90014-x
更新日期：1991-06-01 00:00:00
abstract：:Ankyrins are scaffolding proteins widely expressed throughout the nervous system. Ankyrins recruit diverse membrane proteins, including ion channels and cell adhesion molecules, into specialized subcellular membrane domains. These domains are stabilized by ankyrins interacting with the spectrin cytoskeleton. Ankyrin g...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2021.01.002
更新日期：2021-01-20 00:00:00
abstract：:Recent work suggests that radial glial cells represent many, if not most, of the neuronal progenitors in the developing cortex. Asymmetric cell division of radial glia results in the self-renewal of the radial glial cell and the birth of a neuron. Among the proteins that direct cell fate in Drosophila melanogaster tha...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s0959-4388(03)00013-8
更新日期：2003-02-01 00:00:00
abstract：:Inhibitory molecules in CNS myelin affect axonal regeneration after injury. In the past year, myelin-associated glycoprotein (MAG), a well-characterized myelin protein, has been identified as an inhibitor of axonal regeneration. This finding, together with its established ability to promote outgrowth, defines MAG as a...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/0959-4388(95)80063-8
更新日期：1995-10-01 00:00:00
abstract：:Peripheral nerves show a remarkable ability to regenerate following a transection injury. Downstream of the cut, the axons degenerate and so to regenerate the nerve, the severed axons need to regrow back to their targets and regain function. This requires the axons to navigate through two different environments. (1) T...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2016.04.005
更新日期：2016-08-01 00:00:00
abstract：:Neuroeconomics is an interdisciplinary field, crossing boundaries between Economics, Psychology, and Neuroscience. Its original program was to provide a test for a large number of competitive theories of decision making. It has in part realized this program, and we review the main findings here. But its results are al...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章
doi：10.1016/j.conb.2009.09.012
更新日期：2009-12-01 00:00:00
abstract：:Vocalizations transmit information to social partners, and mice use these signals to exchange information during courtship. Ultrasonic vocalizations from adult males are tightly associated with their interactions with females, and vary as a function of male quality. Work in the last decade has established that the spe...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2015.12.009
更新日期：2016-06-01 00:00:00
abstract：:Despite their differences, human language and the vocal communication of nonhuman primates share many features. Both constitute a form of joint action, rely on similar neural mechanisms, and involve discrete, combinatorial cognition. These shared features suggest that during evolution the ancestors of modern primates ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2014.04.003
更新日期：2014-10-01 00:00:00
abstract：:The perception of music depends on many culture-specific factors, but is also constrained by properties of the auditory system. This has been best characterized for those aspects of music that involve pitch. Pitch sequences are heard in terms of relative as well as absolute pitch. Pitch combinations give rise to emerg...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2008.09.005
更新日期：2008-08-01 00:00:00
abstract：:The ionotropic GABA receptor (GABAAR) mediates fast inhibition in the brain. The GABAAR pore-forming (α, β, and non-α/β) subunits were isolated approximately 30 years ago and have since been the focus of extensive studies. As a result, many properties of GABAARs, including subunit assembly and channel and pharmacologi...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2019.01.017
更新日期：2019-08-01 00:00:00
abstract：:Synapses are specialized sites of cell contact that mediate information flow between neurons and their targets. Genetic screens in the nematode C. elegans have led to the discovery of a number of molecules required for synapse patterning and assembly. Recent studies have demonstrated the importance of guidepost cells ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2008.04.003
更新日期：2008-02-01 00:00:00
abstract：:Recent functional brain imaging studies of the neurobiology of emotion have investigated how individual differences among subjects modulate neural responses during emotion processing. Differences in personality, dispositional affect, biological sex, and genotype can all substantially modulate the neural bases of emoti...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2004.03.010
更新日期：2004-04-01 00:00:00
abstract：:Emerging evidences linking pathological mechanisms of prions and tauopathies are accumulating. However, Tau assemblies do not yet fulfill all the criteria of prions. Here, we review recent data pointing similarities between prions and tauopathies and discuss the still existing uncertainties. ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2019.11.022
更新日期：2020-04-01 00:00:00
abstract：:In the mammalian cortex, the classic view assumes that the output information of a neuron is encoded in rather stereotyped action potentials, which provide an all-or-none or digital way of communication between cell body and axonal boutons. A role for subthreshold signal propagation within cortical axons has largely b...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2008.08.006
更新日期：2008-06-01 00:00:00
abstract：:Understanding how the brain performs computations requires understanding neuronal firing patterns at successive levels of processing-a daunting and seemingly intractable task. Two recent studies have made dramatic progress on this problem by showing how its dimensionality can be reduced. Using the retina as a model sy...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2007.07.002
更新日期：2007-08-01 00:00:00
abstract：:Animals respond to sensory cues emitted by their conspecifics by initiating a repertoire of sex-specific social behaviors, such as mating, fighting, and parental care. These behavioral responses are thought to be largely driven by genetically pre-programmed circuits. However, they can also vary significantly according...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2018.07.005
更新日期：2018-12-01 00:00:00
abstract：:Our understanding of the central nervous system (CNS) development has been strongly enhanced by the recent progress of single-cell multiomics approaches. Certainly, the multiplex profiling of individual cell epigenomes and transcriptomes together with dynamic lineage tracing systems brings encouraging new perspectives...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2020.09.010
更新日期：2020-11-07 00:00:00
abstract：:AMPA receptor (AMPAR) complexes comprise four of the AMPAR subunits GluA1-4 and several additional interacting proteins. Subunit composition determines AMPAR function. However, AMPAR function depends to a large extent also on interacting proteins, which influence trafficking to the cell surface, activity-dependent sub...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2017.03.001
更新日期：2017-08-01 00:00:00
abstract：:Animal eyes have long served as a classical example of independent origin followed by convergence of structures onto a few different solutions. During the past decade this view has been challenged by the discovery of shared developmental regulatory genes. The Pax6 gene in particular is almost universally employed for ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2004.07.004
更新日期：2004-08-01 00:00:00
abstract：:Modulation of local protein synthesis in neuronal dendrites plays a key role in the production of long-term, activity-dependent changes in synapse structure and functional efficacy. Such long-term changes also require regulation of actin dynamics in dendritic spines. Recent evidence couples local protein synthesis to ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2008.09.013
更新日期：2008-10-01 00:00:00
abstract：:Metabotropic L-glutamate receptors are involved in various forms of synaptic plasticity in the hippocampus. The use of a new antagonist (LY341495) that blocks all known metabotropic L-glutamate receptors in the brain, together with subtype-selective antagonists, has identified multiple roles both for cloned and novel ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s0959-4388(99)80044-0
更新日期：1999-06-01 00:00:00
abstract：:Biochemical and physiological evidence has suggested that myosins, both conventional and unconventional, are critical for neurosensory activities. In the past few years, this premise has been supported by genetic evidence that has shown that unconventional myosins are essential for the proper functioning of neurons, r...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s0959-4388(97)80080-3
更新日期：1997-10-01 00:00:00
abstract：:The anterior cingulate cortex (ACC) and adjacent areas of the medial frontal cortex (MFC) have been implicated in monitoring behaviour and in detecting errors. Recent evidence, however, suggests that the ACC not only registers the occurrence of errors but also represents other aspects of the reinforcement history that...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2007.03.001
更新日期：2007-04-01 00:00:00
abstract：:Recent advances in multi-electrode recording have brought us closer to understanding how visual information is encoded by populations of retinal ganglion cells. By monitoring the visual responses of many ganglion cells at once, it is now possible to examine how ganglion cells act together to encode a visual scene. ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s0959-4388(98)80036-6
更新日期：1998-08-01 00:00:00
abstract：:PTEN germline mutations are found in a small subset of children diagnosed with autism spectrum disorder (ASD) and accompanying macrocephaly. In this review, we discuss recent advances that offer insight into the pathogenesis of this subgroup of autism patients. We provide an overview of how disrupting PTEN function in...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2012.05.004
更新日期：2012-10-01 00:00:00
abstract：:The precise causal factors for obsessive-compulsive disorder (OCD) are not known, although, decades of research have honed in on the cortico-striatal-thalamo-cortical (CSTC) circuitry in the brain as a critical pathway involved in obsessions and the intimately linked compulsive-repetitive behaviors. Recent progress in...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2011.04.010
更新日期：2011-12-01 00:00:00
abstract：:Perceptual and control systems are tasked with the challenge of accurately and efficiently estimating the dynamic states of objects in the environment. To properly account for uncertainty, it is necessary to maintain a dynamical belief state representation rather than a single state vector. In this review, canonical a...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2014.01.018
更新日期：2014-04-01 00:00:00
abstract：:The fruit fly, Drosophila melanogaster, is equipped with a sophisticated olfactory sensory system that permits it to recognize and discriminate hundreds of discrete odorants. The perception of these odorants is essential for the animal to identify relevant food sources and suitable sites for egg-laying. Advances in th...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s0959-4388(00)00111-2
更新日期：2000-08-01 00:00:00
abstract：:Major technical advances in the imaging of live cells have led to a recent flurry of studies demonstrating how dendrites remodel dynamically during development. Taken together with our current understanding of axonal development, these studies help provide a more unified picture of how neural circuits might be formed ...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s0959-4388(99)00059-8
更新日期：2000-02-01 00:00:00
abstract：:This past year has seen significant advances in our understanding of the physiology of emotion. Attention continues to focus on the amygdala and its interconnections with prefrontal cortical regions. New evidence underscores the importance of lateralization for emotion. There are also new findings on the physiological...
journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/0959-4388(95)80029-8
更新日期：1995-04-01 00:00:00
