Abstract:
:To evaluate the influence of delay between first symptom and first treatment upon survival the medical records of 596 patients with breast cancer were reviewed. The following intervals were considered: less than 3 months; 3-6 months and greater than 6 months. Patients in the less than 3 months delay group had a better distribution by clinical stages and a 10-year survival rate higher than those in the longer delay groups (p = 0.034). However, within each stage no statistically significant difference in survival according to delay was observed. A Cox multivariate analysis revealed that performance status and stage of disease were independent predictors of survival, but not delay. Assuming the best prognosis for patients with clinical stages I and II and less than 3 months delay, the group with longer delay times had 15 deaths over what would have been predicted. This adverse effect was observed almost exclusively among patients over age 50 (14/15).
journal_name
Oncologyjournal_title
Oncologyauthors
Machiavelli M,Leone B,Romero A,Perez J,Vallejo C,Bianco A,Rodriguez R,Estevez R,Chacon R,Dansky Cdoi
10.1159/000226689subject
Has Abstract,Author List Incompletepub_date
1989-01-01 00:00:00pages
78-82issue
2eissn
0030-2414issn
1423-0232journal_volume
46pub_type
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