Phase I/II Trial of Chemotherapy with Docetaxel, Cisplatin, and S-1 for Unresectable Advanced Squamous Cell Carcinoma of the Esophagus.

abstract：:Thirty-five patients with metastatic breast cancer who had received one or two prior chemotherapeutic regimens were treated with elliptinium acetate at a dose of 80 mg/m2 for 3 days every 3 weeks. Of the 33 patients evaluable for response, 1 patient achieved complete remission, 4 achieved partial responses (15% overal...

journal_title：Oncology

authors： Buzdar AU,Hortobagyi GN,Esparza LT,Holmes FA,Ro JS,Fraschini G,Lichtiger B

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:It was the aim of this study to evaluate clinicopathological characteristics and prognostic factors of uterine leiomyosarcomas (LMS). METHODS:Twenty-eight patients with uterine LMS were evaluated in this retrospective study. Their features and survival were analyzed by Kaplan-Meier and log-rank tests. RESU...

journal_title：Oncology

authors： Loizzi V,Cormio G,Nestola D,Falagario M,Surgo A,Camporeale A,Putignano G,Selvaggi L

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical and cost benefits of the administration of aprepitant for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) during high-dose chemotherapy (HDCT). METHODS:We retrospectively reviewed the charts of patients who received HDCT at our institution between January 2009 and ...

journal_title：Oncology

authors： Nakamura A,Kojima Y,Miyazawa K,Matsumoto S,Iida H,Nagai H

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to identify biomarkers for predicting the efficacy of docetaxel, cisplatin, and S-1 (DCS) therapy for advanced gastric cancer using microarrays of biopsy specimens before chemotherapy. METHODS:Nineteen samples were taken from 19 patients with unresectable metastatic gastric cancer ...

journal_title：Oncology

authors： Kitamura S,Tanahashi T,Aoyagi E,Nakagawa T,Okamoto K,Kimura T,Miyamoto H,Mitsui Y,Rokutan K,Muguruma N,Takayama T

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the treatment outcomes of second-line treatment with pazopanib or gemcitabine/docetaxel in patients with advanced soft tissue sarcoma (STS). METHODS:Ninety-one patients who were treated with pazopanib or gemcitabine/docetaxel for advanced STS between 1995 and 2015 were analyz...

journal_title：Oncology

authors： Kim JH,Park HS,Heo SJ,Kim SK,Han JW,Shin KH,Kim SH,Hur H,Kim KS,Choi YD,Kim S,Lee YH,Suh JS,Ahn JB,Chung HC,Noh SH,Rha SY,Kim HS

更新日期：2019-01-01 00:00:00

abstract：:There are numerous data on the immunostimulative and antitumorous activity of various Viscum album tissue extracts. Isorel (Novipharm, Austria) is one of these compounds. We found that in mice an increased number of plaque-forming cells to sheep red blood cells (SRBC) followed the injection of Isorel together with SRB...

journal_title：Oncology

authors： Jurin M,Zarković N,Hrzenjak M,Ilić Z

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:Uveal melanoma primarily metastasizes hematogenously with metastases often confined to the liver. The aim of this study was to investigate the presence of circulating tumor cells (CTC) in patients with metastatic disease as a marker for systemic disease and to determine their prognostic relevance. METHODS:Bl...

journal_title：Oncology

authors： Schuster R,Bechrakis NE,Stroux A,Busse A,Schmittel A,Thiel E,Foerster MH,Keilholz U

更新日期：2011-01-01 00:00:00

abstract：:1-beta-D-Arabinofuranosylcytosine-5'-stearylphosphate (fosteabine) was administered orally to patients with myelodysplastic syndromes (MDS); refractory anemia with excess of blasts (RAEB), RAEB in transformation, acute leukemia derived from RAEB and chronic myelomonocytic leukemia, in an early phase II study in a mult...

journal_title：Oncology

authors： Ohno R,Tatsumi N,Hirano M,Imai K,Mizoguchi H,Nakamura T,Kosaka M,Takatsuki K,Yamaya T,Toyama K

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Bevacizumab (Avastin) significantly improves overall survival (OS) and progression-free survival (PFS) when combined with first-line irinotecan (IFL) plus bolus 5-fluorouracil (5-FU) and leucovorin (LV) in patients with metastatic colorectal cancer (CRC). This open-label, phase IV trial evaluated the efficac...

journal_title：Oncology

authors： Sobrero A,Ackland S,Clarke S,Perez-Carrión R,Chiara S,Gapski J,Mainwaring P,Langer B,Young S,AVIRI Trial investigators.

更新日期：2009-01-01 00:00:00

abstract：:Breast tumorigenesis is a continuum from preinvasive lesions to early breast cancer and advanced disease. In this article the data supporting the use of the aromatase inhibitor anastrozole in postmenopausal women across this continuum are reviewed. In advanced disease, anastrozole has a significant survival benefit an...

journal_title：Oncology

authors： Nabholtz JM

更新日期：2006-01-01 00:00:00

abstract：:6 cases of endodermal sinus tumor of the ovary are presented. In 4 patients pure endodermal sinus tumor was found microscopically. 1 patient had endodermal sinus tumor in one ovary and gonadoblastoma in the contralateral one. In another case endodermal sinus tumor was accompanied by an embryonal teratoma. Histological...

journal_title：Oncology

authors： Sikorowa L,Morawski A,Piatkowski Z

更新日期：1979-01-01 00:00:00

abstract：:Until a few decades ago neck dissection (ND) was the standard surgical approach for node-positive tumours. Nowadays patients with locally advanced head and neck cancer can be treated with definitive chemoradiation (CRT), which includes the treatment of the neck; however, results on residual viable tumour after conserv...

journal_title：Oncology

authors： Denaro N,Russi EG,Numico G,Pazzaia T,Vitiello R,Merlano MC

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Previous data showed that distant metastatic breast cancer (MBC) might be curable in up to 3% of the cases in selected patients, mostly young, with good performance status and with low-volume metastatic disease, mainly by an aggressive multidisciplinary approach including aggressive combination chemotherapy ...

journal_title：Oncology

authors： Güth U,Elfgen C,Montagna G,Schmid SM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Ethnic disparities in cancers are associated with variability in clinical outcomes. We present a Surveillance Epidemiology and End RESULTS (SEER)-based outcome analysis of multiethnic Waldenström's macroglobulinemia (WM) patients. METHODS:Adult WM patients diagnosed in 1992 or later (n = 3,175) were analyze...

journal_title：Oncology

authors： Ailawadhi S,Kardosh A,Yang D,Cozen W,Patel G,Alamgir MA,Chanan-Khan AA

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:BRAF D594G mutations in colorectal cancer patients are not clearly understood. We retrospectively investigated the clinicopathological features of colorectal cancers with BRAF D594G mutations. METHODS:We selected 908 colorectal cancer patients who underwent surgical resection from January 2008 to January 201...

journal_title：Oncology

authors： Amaki-Takao M,Yamaguchi T,Natsume S,Iijima T,Wakaume R,Takahashi K,Matsumoto H,Miyaki M

更新日期：2016-01-01 00:00:00

abstract：:Eleven postmenopausal patients with advanced breast cancer were assessed for their response and endocrine changes to low-dose aminoglutethimide (250 mg twice a day) therapy without steroid administration. In 7 cases an objective response was registered; 1 patient had a stabilization of the disease lasting for 9 months...

journal_title：Oncology

authors： Kahán Z,Tóth I,Vecsernyés M

更新日期：1992-01-01 00:00:00

abstract：:The relationship of vitamins to cancer is very complex. Three types of interactions are possible: the effect of vitamins on tumor growth, the effect of tumors on vitamin metabolism, and the effect of vitamins on chemical carcinogens and anti-tumor chemotherapeutic agents. The significance of vitamins with particular r...

journal_title：Oncology

authors： Basu TK

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:To better determine docetaxel activity in patients with well-defined anthracycline-resistant breast cancer. METHODS:From October 1996, we carried out a phase II trial in 69 heavily pretreated patients with advanced breast cancer with docetaxel 100 mg/m(2) by a 1-hour infusion on day 1, with cycles repeated e...

journal_title：Oncology

authors： Vici P,Belli F,Di Lauro L,Amodio A,Conti F,Foggi P,Gionfra T,Morelli MF,Botti C,Ferraironi A,Lopez M

更新日期：2001-01-01 00:00:00

abstract：:As the antitumor activity of radiation is mediated via its interaction with oxygen to form labile free radicals, the intratumoral oxygen level has an important influence on the ability of radiation therapy to kill malignant cells. By decreasing the oxygen-carrying capacity of the blood, anemia may result in tumor hypo...

journal_title：Oncology

authors： Harrison LB,Shasha D,Homel P

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The clinical features of hepatocellular carcinoma (HCC) differ in patients with and without cirrhosis. OBJECTIVE:We aimed to investigate the long-term outcomes of noncirrhotic HCC patients after curative resection. METHODS:We retrospectively examined 649 consecutive patients with HCC who underwent curative...

journal_title：Oncology

authors： Lee HW,Choi GH,Kim DY,Park YN,Kim KS,Choi JS,Ahn SH,Han KH

更新日期：2017-01-01 00:00:00

abstract：:The paper presents the experience with watch-and-wait policy following radical surgery in 25 patients with primary gastric non-Hodgkin's (NH) lymphoma localized to the gastric wall. The median follow-up is at the moment 40 months (range 18-85). Only 3/25 patients have relapsed (during the first year of the follow-up) ...

journal_title：Oncology

authors： Jelić S,Kovcin V,Jovanović V,Oprić M,Milanović N

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:There are a few long-term follow-up studies of patients with stage I ovarian carcinoma. The objective of this study was to evaluate prognostic factors for long-term survival. METHODS:Two hundred fourteen stage I ovarian carcinomas (registered by the Tokai Ovarian Tumor Study Group from 1988 to 1999) were ana...

journal_title：Oncology

authors： Mizuno M,Kikkawa F,Shibata K,Kajiyama H,Suzuki T,Ino K,Kawai M,Mizutani S

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES AND METHODS:The association oxaliplatin (OXA)-5-fluorouracil/folinic acid (FUFA) is currently a standard first-line treatment for advanced colorectal cancer. The main objective of this experimental study was to examine the cytotoxic effects resulting from the addition of ionizing radiation (Rgamma) to the co...

journal_title：Oncology

authors： Magné N,Fischel JL,Formento P,Etienne MC,Dubreuil A,Marcié S,Lagrange JL,Milano G

更新日期：2003-01-01 00:00:00

abstract：AIM:The aim of this study was to assess the molecular subtype profiles of male breast cancer (MBC) and subsequent clinical outcome using a validated 6-marker immunohistochemical panel. METHODS:A total of 43 cases of MBC were examined retrospectively using a semiquantitative immunohistochemical analysis of estrogen rec...

journal_title：Oncology

authors： Sánchez-Muñoz A,Román-Jobacho A,Pérez-Villa L,Sánchez-Rovira P,Miramón J,Pérez D,Sáez MI,de Luque V,Medina L,Ramírez-Tortosa CL,Vicioso L,Medina JA,Ribelles N,Alba E

更新日期：2012-01-01 00:00:00

abstract：:The Abelson-virus-induced murine lymphosarcoma cell line RAW117-P and its in vivo selected highly malignant and metastatic variant RAW117-H10 have been studied for their growth in vivo, in vitro and in semi-solid agar. The highly malignant metastatic variant RAW117-H10 cells killed syngeneic Balb/c mice rapidly and fo...

journal_title：Oncology

authors： Joshi SS,Sharp JG,Brunson KW

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Irinotecan has, in general, been administered as a 90-min infusion. However, several studies have demonstrated that continuous infusion seems to be a promising method of delivering irinotecan. This phase I/II trial was performed to evaluate the efficacy and safety of continuous infusion of irinotecan combined...

journal_title：Oncology

authors： Sadahiro S,Suzuki T,Maeda Y,Tanaka A,Ishikawa K,Makuuchi H,Murayama C

更新日期：2009-01-01 00:00:00

abstract：:This paper presents clinical observations on 130 patients with carcinoma of the pancreas, including 19 with periampullary cancer, the first large study of this disease in Iraq. All of the patients were admitted to the First (one of three) Surgical Unit of the University of Baghdad Teaching Hospital (the Medical City) ...

journal_title：Oncology

authors： Al-Bahrani ZR,Al-Mondhiry HA,Al-Saleem T

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:To report the outcomes of surgical resection of borderline resectable (BL) and locally advanced (LA) 'unresectable' pancreatic cancer after neoadjuvant chemotherapy. METHODS:A review of a prospectively maintained database for pancreatic resections was undertaken to identify patients undergoing resection for ...

journal_title：Oncology

authors： Addeo P,Rosso E,Fuchshuber P,Oussoultzoglou E,De Blasi V,Simone G,Belletier C,Dufour P,Bachellier P

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the outcomes of gemcitabine-treated patients with inoperable biliary tract cancers. METHODS:We conducted a retrospective study of consecutively treated 22 inoperable biliary tract cancer patients with gemcitabine (500-1,000 mg/m(2) on days 1, 8, 15 every 4 weeks) as f...

journal_title：Oncology

authors： Kiba T,Nishimura T,Matsumoto S,Hatano E,Mori A,Yasumi S,Doi R,Ikai I,Kitano T,Nishimura T,Yoshikawa K,Ishiguro H,Yanagihara K,Doi E,Teramukai S,Fukushima M

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Carcinoma of the biliary system is a rare tumor entity, and patients with advanced disease face a dismal prognosis. Because of the absence of standard chemotherapy for advanced biliary carcinoma, we have performed two consecutive studies to evaluate the clinical potential of 5-fluorouracil, leucovorin and ...

journal_title：Oncology

authors： Raderer M,Hejna MH,Valencak JB,Kornek GV,Weinländer GS,Bareck E,Lenauer J,Brodowicz T,Lang F,Scheithauer W

更新日期：1999-04-01 00:00:00