当前位置： SCI文献检索 > CLINICAL BIOCHEMISTRY期刊下所有文献 > Effects of two types of medical contrast media on routine chemistry results by three automated chemistry analyzers.

Effects of two types of medical contrast media on routine chemistry results by three automated chemistry analyzers.

Abstract：

OBJECTIVES:The use of iodinated contrast media has grown in popularity in the past two decades, but relatively little attention has been paid to the possible interferential effects of contrast media on laboratory test results. Herein, we investigate medical contrast media interference with routine chemistry results obtained by three automated chemistry analyzers. METHODS:Ten levels of pooled serum were used in the study. Two types of medical contrast media [Iopamiro (iopamidol) and Omnipaque (iohexol)] were evaluated. To evaluate the dose-dependent effects of the contrast media, iopamidol and iohexol were spiked separately into aliquots of serum for final concentrations of 1.8%, 3.6%, 5.5%, 7.3%, and 9.1%. The 28 analytes included in the routine chemistry panel were measured by using Hitachi 7600, AU5800, and Cobas c702 analyzers. We calculated the delta percentage difference (DPD) between the samples and the control, and examined dose-dependent trends. RESULTS:When the mean DPD values were compared with the reference cut-off criteria, the only uniformly interferential effect observed for all analyzers was in total protein with iopamidol. Two additional analytes that showed trends toward interferential effects only in few analyzers and exceeded the limits of the allowable error were the serum iron and the total CO2. The other combinations of analyzer and contrast showed no consistent dose-dependent propensity for change in any analyte level. CONCLUSIONS:Our study suggests that many of the analytes included in routine chemistry results, except total protein and serum iron, are not significantly affected by iopamidol and iohexol. These results suggest that it would be beneficial to apply a flexible medical evaluation process for patients requiring both laboratory tests and imaging studies, minimizing the need for strict regulations for sequential tests.

journal_name

Clin Biochem

journal_title

Clinical biochemistry

authors

Park YJ,Rim JH,Yim J,Lee SG,Kim JH

doi

10.1016/j.clinbiochem.2017.02.023

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

719-725

issue

12

eissn

0009-9120

issn

1873-2933

pii

S0009-9120(16)30679-8

journal_volume

50

pub_type

杂志文章

相关文献

CLINICAL BIOCHEMISTRY文献大全
  • Monoclonal antibody technology for cyclosporine monitoring.

    abstract：:Monitoring blood levels of Cyclosporine (CsA) has been the basis for adjusting individual dosage regimens in the clinic. Radioimmunoassays using polyclonal antisera reacted with CsA and some CsA metabolites, leading to overestimation when compared with high-performance liquid chromatographic measurements of CsA. Monoc...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/0009-9120(91)90147-7

    authors： Quesniaux VF

    更新日期：1991-02-01 00:00:00

  • Tentative identification of hemoglobin variants in the Bio-Rad VARIANT II Hb A1C method.

    abstract：OBJECTIVE:To evaluate if peak characteristics, the retention time, and percentage of total hemoglobin of an unknown peak on the Bio-Rad VARIANT II Hb A1c method may be used to establish a tentative identification of hemoglobin variants. METHOD:The peak characteristics, retention time, and percentage of total hemoglobi...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2004.11.004

    authors： Higgins TN,Ridley B

    更新日期：2005-03-01 00:00:00

  • 1,5-anhydroglucitol monitoring in diabetes: a mass balance perspective.

    abstract：:1,5-anhydroglucitol (AG) is a nonmetabolizable glucose analogue found in plasma due to ingestion. The normal steady-state concentration can be dramatically decreased by inhibition of tubular reabsorption during periods of hyperglycemia. For this reason, monitoring of AG has been plausibly advocated for detection of pe...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.clinbiochem.2008.08.086

    authors： Nerby CL,Stickle DF

    更新日期：2009-02-01 00:00:00

  • A simplified assay for serum 25-hydroxycalciferol.

    abstract：:The measurement of serum 25-hydroxycalciferol (25-OH D) has proved to be a reliable index of the vitamin D nutritional status in man providing the renal 25-hydroxycalciferol-1 alpha-hydroxylase is functional. Since it is known that 25 OHD binds to alpha-globulins for its transport to the kidney, we have developed a co...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0009-9120(80)90735-3

    authors： Delvin EE,Dussault M,Glorieux FH

    更新日期：1980-06-01 00:00:00

  • Quantification of urinary allantoin by capillary zone electrophoresis during recombinant urate oxydase (rasburicase) therapy.

    abstract：OBJECTIVES:Rasburicase (Fasturtec) is used to prevent or treat hyperuricemia associated with chemotherapy. We developed a capillary zone electrophoresis method to measure urinary allantoin, the degradation product of uric acid by rasburicase. DESIGN AND METHODS:Electrophoresis was performed using a P/ACE 5500 system (...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2005.09.013

    authors： Kattygnarath D,Mounier N,Madelaine-Chambrin I,Gourmel B,Le Bricon T,Gisselbrecht C,Faure P,Houzé P

    更新日期：2006-01-01 00:00:00

  • Adult cystatin C reference intervals determined by nephelometric immunoassay.

    abstract：OBJECTIVE:The aim of this study was to determine the adult reference values for cystatin C (CysC) and to evaluate their consistence with those reported in the literature. DESIGN AND METHODS:CysC was analyzed in a consecutive series of subjects (100 males and 100 females) by a nephelometric immunoassay. Medline was sea...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2007.05.011

    authors： Croda-Todd MT,Soto-Montano XJ,Hernández-Cancino PA,Juárez-Aguilar E

    更新日期：2007-09-01 00:00:00

  • Influence of reduction in the elution times on HPLC glycohaemoglobin results.

    abstract：OBJECTIVES:To compare HPLC methods with short and long elution times for HbA1c measurement in blood. METHODS:Comparison between G7-Tosoh (1.2 min); Bio-Rad-Variant-II-Turbo (1.3 min) and Arkray-HA-8160 (2.9 min). RESULTS:Passing-Bablok regression equations were: Y=0.17+0.96X; Y=-0.39+1.01X; Y=-0.40+1.0X and the means...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2009.07.003

    authors： Leon-Justel A,Santotoribio JD,Dominguez-Pascual I,Delgado AL,Macias C,Herrera MT,Leal A,Mangas MA,Acosta D,Guerrero JM

    更新日期：2009-10-01 00:00:00

  • Signaling for ethanol-induced apoptosis and repair in vitro.

    abstract：OBJECTIVES:To evaluate whether caspases are involved in ethanol (EtOH)-induced apoptosis and if polyenylphosphatidylcholine (PPC) affects apoptosis, in vitro in Hep G2 cells. METHODS:Cells were treated with 100 mmol/L EtOH for 24 h and with 2 doses of 100 mmol/L EtOH (1/24 h) in the presence of absence of 20 mmol/L of...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0009-9120(01)00218-1

    authors： Katz GG,Shear NH,Malkiewicz IM,Valentino K,Neuman MG

    更新日期：2001-05-01 00:00:00

  • Quantitative analysis of trace elements in human blood and plasma by energy dispersive X-ray fluorescence.

    abstract：:A photon excitation, secondary target x-ray fluorescence system was used to measure concentrations of Cu, Zn, Br and Rb in whole blood and plasma of healthy adults. The samples preparation method and calculated limits of detection of the technique are reported. Correlation statistics for elemental concentrations have ...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0009-9120(77)91740-4

    authors： Stump IG,Carruthers J,D'Auria JM

    更新日期：1977-06-01 00:00:00

  • CD62L on neutrophil granulocytes, a useful, complementary marker for the prediction of ventriculitis in blood-containing CSF.

    abstract：OBJECTIVES:Presence of residual blood is a common problem in cerebrospinal fluid (CSF) diagnostics of ventriculitis. We hypothesised that neutrophil granulocytes in infected, blood-containing CSF lose CD62L expression. Therefore CD62L expression on neutrophils may present a complementary marker to distinguish between p...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2010.07.003

    authors： Boer K,Vogelsang H,Deufel T,Pfister W,Kiehntopf M

    更新日期：2010-11-01 00:00:00

  • Circulating miRNA as fine regulators of the physiological responses to physical activity: Pre-analytical warnings for a novel class of biomarkers.

    abstract：:MicroRNAs are endogenous non-coding RNAs that post-transcriptionally regulate gene expression by specifically binding the target mRNA and by consequently inducing its degradation. miRNAs can be released into the circulation where they remain stable and they can be measured. Their changes reflect individual biologic ad...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.clinbiochem.2016.09.017

    authors： Lombardi G,Perego S,Sansoni V,Banfi G

    更新日期：2016-12-01 00:00:00

  • Optimizing RNA extraction yield from whole blood for microarray gene expression analysis.

    abstract：OBJECTIVES:Microarray analysis of gene expression profiles of blood leukocytes has many potential clinical and research applications. DESIGN AND METHODS:We used the PAXgene Blood RNA System to prepare RNA from the whole blood of normal volunteers using two incubation times followed by gene expression profiling using t...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2004.03.013

    authors： Wang J,Robinson JF,Khan HM,Carter DE,McKinney J,Miskie BA,Hegele RA

    更新日期：2004-09-01 00:00:00

  • Serum HDL-C levels, log (TG/HDL-C) values and serum total cholesterol/HDL-C ratios significantly correlate with radiological extent of disease in patients with community-acquired pneumonia.

    abstract：BACKGROUND:In several studies, it was shown that there was a marked decrease in serum levels of HDL-C during infection and inflammation in general. In particular, a decrease in the level of serum HDL-C was also shown in pneumonia. Correlations between inflammatory markers such as acute phase proteins, cytokines and ser...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2006.01.015

    authors： Deniz O,Tozkoparan E,Yaman H,Cakir E,Gumus S,Ozcan O,Bozlar U,Bilgi C,Bilgic H,Ekiz K

    更新日期：2006-03-01 00:00:00

  • Effect of second and third generation oral contraceptives on C-reactive protein, lipids and apolipoproteins in young, non-obese, non-smoking apparently healthy women.

    abstract：OBJECTIVE:Third generation oral contraceptives (OC) may increase the risk of cardiovascular events in healthy young women. DESIGN AND METHODS:We assessed the effect of second and third generation OC on CRP, lipids and apolipoproteins in 128 women. RESULTS:CRP was significantly higher in third generation contraceptive...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2009.12.013

    authors： Krintus M,Sypniewska G,Kuligowska-Prusinska M

    更新日期：2010-04-01 00:00:00

  • Heparin affects matrix metalloproteinases and tissue inhibitors of metalloproteinases circulating in peripheral blood.

    abstract：OBJECTIVES:Blood sampling/handling alters matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression. The aim of this study is to evaluate the effects of high molecular weight heparin on MMP and TIMP expression in blood. DESIGN AND METHODS:We analyzed by gelatin zymography and ELISA ...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2008.09.104

    authors： Mannello F,Jung K,Tonti GA,Canestrari F

    更新日期：2008-12-01 00:00:00

  • Simultaneous detection and screening of T833C and G919A mutations of the cystathionine beta-synthase gene by single-strand conformational polymorphism.

    abstract：OBJECTIVE:We used single-strand conformational polymorphism (SSCP) to screen for mutations at nucleotides 833 and 919 of the cystathionine beta-synthase (CBS) gene in 13 patients with homocystinuria and 11 of their relatives. METHODS:Exon 8 of genomic DNA was selectively amplified by PCR using primers derived from int...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/0009-9120(96)00045-8

    authors： Tsai MY,Hanson NQ,Bignell MK,Schwichtenberg KA

    更新日期：1996-10-01 00:00:00

  • Serum calprotectin levels in elderly males and females without bacterial or viral infections.

    abstract：OBJECTIVES:Calprotectin is released from activated leukocytes and calprotectin can thus be used as a marker for leukocyte activation. Faeces calprotectin is not only used as a marker for inflammatory bowel disease but can also be used to detect leukocyte activation in other body fluids. The aim of the present study was...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2014.01.003

    authors： Nilsen T,Sundström J,Lind L,Larsson A

    更新日期：2014-08-01 00:00:00

  • Biochemistry and clinical chemistry of vitamin B12 transport and the related diseases.

    abstract：:This review focusses on research performed by the author and coworkers. The absorption, turnover and excretion of cobalamin and the pathogenesis of cobalamin deficiency states are described and the laboratory tests used to diagnose these states are discussed. Topics dealt with in detail include: overall turnover, dail...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/s0009-9120(84)90279-0

    authors： Gräsbeck R

    更新日期：1984-04-01 00:00:00

  • Urinary beta-luteinizing hormone and beta-follicle stimulating hormone immunoenzymometric assays for population research.

    abstract：OBJECTIVE:We developed assays for measurement of urinary betaLH and betaFSH under collection and storage conditions typical of non-clinical research settings. DESIGN AND METHODS:IEMAs for free betaLH and total betaFSH were validated by standard methods. Stability of urinary betaLH and betaFSH was tested across freeze-...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2006.08.009

    authors： Brindle E,Miller RC,Shofer JB,Klein NA,Soules MR,O'Connor KA

    更新日期：2006-11-01 00:00:00

  • Quantification of the variation due to lysing technique in immunophenotyping of healthy and HIV-infected individuals.

    abstract：OBJECTIVE:We performed a side-by-side comparison between three stain-then-lyse commercially available methods (Ortho-mune Lysing solution, FACS lysing solution and ImmunoPrep reagent system) and a lyse-then-stain method using hypotonic NH4Cl. The major difference between these methods is that only in the latter the ali...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0009-9120(98)00011-3

    authors： Pacifici R,Zuccaro P,Cozzi-Lepre A,di Carlo S,Bacosi A,Fattorossi A

    更新日期：1998-04-01 00:00:00

  • The role of interleukin-12 in the pathogenesis of psoriasis.

    abstract：OBJECTIVES:To verify the role of IL-12 in the pathogenesis of psoriasis and determine its relation to IFNgamma. DESIGN AND METHODS:Skin biopsies from lesional and non-lesional skin of 30 patients and 10 healthy controls were obtained for quantitative PCR examination of IL-12 (P40) and IFNgamma mRNA as well as in situ ...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2005.11.008

    authors： Shaker OG,Moustafa W,Essmat S,Abdel-Halim M,El-Komy M

    更新日期：2006-02-01 00:00:00

  • The thyroid stimulating hormone receptor in human disease.

    abstract：:The initial step in the action of thyrotropin (TSH) is its binding to the TSH receptor. TSH receptor antibodies are detected in up to 90% of patients with Graves' disease. Serial measurements of TSH receptor antibodies in patients with Graves' hyperthyroidism are helpful in predicting relapse. The TSH receptor was pur...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/0009-9120(90)90417-s

    authors： Harrison LC,Leedman PJ

    更新日期：1990-02-01 00:00:00

  • Spurious hyperbilirubinemia caused by naproxen.

    abstract：OBJECTIVE:To confirm that the naproxen metabolite O-desmethylnaproxen interferes with the Jendrassik and Grof method for total bilirubin and was a possible cause of spurious hyperbilirubinemia in a case of naproxen overdose. DESIGN AND METHODS:Plasma was spiked with naproxen or O-desmethylnaproxen before total and dir...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2008.09.119

    authors： Al Riyami N,Zimmerman AC,Rosenberg FM,Holmes DT

    更新日期：2009-01-01 00:00:00

  • Comparison of predose vs 2-h postdose blood metabolites/cyclosporine ratios in kidney and liver transplant patients.

    abstract：OBJECTIVES:It has recently been suggested that when adjusting doses of cyclosporine (CsA), determining its concentration in blood samples taken 2 h postdose (C(2)) is more clinically beneficial than using the predose concentration (C(0)). We determined C(0) and C(2) concentrations of CsA and their metabolites in sample...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0009-9120(00)00147-8

    authors： Fernández-Marmiesse A,Hermida J,Tutor JC

    更新日期：2000-07-01 00:00:00

  • Cathepsin D levels are reduced in patients with preeclampsia in Korean population.

    abstract：OBJECTIVES:To compare the circulating levels of cathepsin D in preeclamptic and normotensive pregnancies. DESIGN AND METHODS:Fifty pregnant and 20 healthy non-pregnant patients were enrolled in this study. Of the 50 pregnant patients, 15 were preeclamptic and 35 patients were normotensive. Serum levels of soluble cath...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2013.07.022

    authors： Kim HY,Lee M,Kang HW,Moon C

    更新日期：2013-12-01 00:00:00

  • Heart-type fatty acid binding protein in elective cardioversion of atrial fibrillation.

    abstract：OBJECTIVES:We sought to investigate whether heart-type fatty acid binding protein (H-FABP), a new marker of myocardial necrosis, increases in relation to elective cardioversion of atrial fibrillation (AF). METHODS:We studied 25 consecutive patients (61 ± 16 years old, 21 men) admitted to our hospital for elective card...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2011.05.029

    authors： Sbarouni E,Georgiadou P,Chaidaroglou A,Degiannis D,Voudris V

    更新日期：2011-08-01 00:00:00

  • An ELISA for plasma retinol-binding protein using monoclonal and polyclonal antibodies: plasma variation in normal and insulin resistant subjects.

    abstract：OBJECTIVES:Plasma retinol-binding protein (RBP) has been linked to insulin resistance and cardiovascular risk, yet little is know of its natural variation in plasma. We examined this in normal subjects and compared plasma levels and variability in lean subjects and subjects with the metabolic syndrome. METHODS:We esta...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.clinbiochem.2007.03.021

    authors： Lewis JG,Shand BI,Frampton CM,Elder PA

    更新日期：2007-07-01 00:00:00

  • Fluorometric and time-resolved immunofluorometric assays for protein-tyrosine phosphatase activity.

    abstract：OBJECTIVE:To develop sensitive nonisotopic assays for protein-tyrosine phosphatase (PTP) activity. METHODS:The fluorometric assay is based on the fact that phosphotyrosine but not tyrosine forms highly fluorescent complexes with Tb3+. Thus, PTP activity can be followed by measuring the decrease of fluorescence due to ...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/0009-9120(95)02026-8

    authors： Galvan B,Christopoulos TK

    更新日期：1996-04-01 00:00:00

  • Inherited factor V deficient neonate with galactosaemia.

    abstract：OBJECTIVES:Reporting a case of inherited factor V deficiency and galactosemia. METHODS:A neonate was admitted with hematoma, jaundice, splenomegaly, diarrhea, anemia, abdominal ascites and bilateral cataracts that diagnosis of galactosaemia and factor V deficiency was established. RESULTS:Coinheritance of both coagul...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.clinbiochem.2011.12.024

    authors： Mansouritorghabeh H,Sharifi-Hoseini MR,Shahroudian M

    更新日期：2012-03-01 00:00:00

  • Lipid peroxidation and antioxidant system in the blood of patients with Hodgkin's disease.

    abstract：OBJECTIVES:The purpose of this study was to measure the extent of lipid peroxidation and the status of antioxidants in patients with Hodgkin's disease. DESIGN AND METHODS:Glutathione peroxidase (GPX) and superoxide dismutase (SOD) activities, and malondialdehyde (MDA), selenium, zinc and copper content have been measu...

    journal_title：Clinical biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0009-9120(00)00062-x

    authors： Güven M,Oztürk B,Sayal A,Ozet A

    更新日期：2000-04-01 00:00:00