Spurious hyperbilirubinemia caused by naproxen.

abstract：OBJECTIVES:We undertook the present study to investigate the possible relation between total antioxidant capacity (TAC) and tumor marker (TM) values in serum samples of patients with and without gastrointestinal tract and prostate tumors. DESIGN AND METHODS:We measured the TAC using trolox equivalent antioxidant capac...

journal_title：Clinical biochemistry

authors： López Vélez M,Martínez Martínez F

更新日期：2011-09-01 00:00:00

abstract：:An automated biotin-streptavidin procedure for measuring progesterone in serum is described. The method is linear up to 98.3 nmol/L and the calibration curve is stable for at least 14 days. The lower limit of progesterone detection is 0.70 nmol/L. Although serum is the preferred specimen, progesterone levels can be me...

journal_title：Clinical biochemistry

authors： Pesce MA,Bodourian SH,Sheehan M,Henkel CF

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Given that both insufficient and excess maternal iodine have adverse consequences such as poor cognitive performance, delayed physical development and increased fetal and infant mortality, the determination of maternal iodine status is very important. In this study, we established and verified a method invol...

journal_title：Clinical biochemistry

authors： Zou Y,Wang D,Yu S,Cheng X,Xia L,Yin Y,Xie S,Cheng Q,Qiu L,Lian X

更新日期：2020-08-01 00:00:00

abstract：:Two studies are described in this paper for the purpose of extending the application of the Dupont ACA glucose method to (1) analysis of specimens containing sodium fluoride and sodium iodoacetate, and (2) analysis of specimens containing EDTA, provided analysis is conducted immediately following specimen collection a...

journal_title：Clinical biochemistry

authors： Dubois JA,Roberts G,Beekman J

更新日期：1982-04-01 00:00:00

abstract：:Proteomics, the analysis of expressed proteins, has been an important developing area of research for the past two decades [Anderson, NG, Anderson, NL. Twenty years of two-dimensional electrophoresis: past, present and future. Electrophoresis 1996;17:443-453]. Advances in technology have led to a rapid increase in app...

journal_title：Clinical biochemistry

authors： Aldred S,Grant MM,Griffiths HR

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:To characterize a novel deletion of exon 3 of CFTR gene and to evaluate the implications in Cystic Fibrosis (CF) care and genetic counseling. DESIGN AND METHODS:We performed a wide mutational analysis of CFTR gene, using reverse dot blot, Multiplex Ligation-dependent Probe Amplification (MLPA) assay and Rea...

journal_title：Clinical biochemistry

authors： Tomaiuolo AC,Sirleto P,Centrone C,Surace C,Alghisi F,Petrocchi S,Lombardo A,Rossi M,Torricelli F,Lucidi V,Angioni A

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to find a pre-interventional marker with the capacity to predict in-stent restenosis (ISR). Considering the anti-atherosclerotic role of adiponectin (APO), an adipocytokine with anti-inflammatory, anti-proliferative, anti-oxidative and anti-thrombotic properties, low plasma levels of...

journal_title：Clinical biochemistry

authors： Moldoveanu E,Mut-Vitcu B,Tanaseanu GR,Marta DS,Manea G,Kosaka T,Vidulescu C,Tanaseanu C

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:All patients who undergo cardiopulmonary bypass (CPB) experience some degree of ischemia reperfusion injury (IRI). Severe IRI-induced acute kidney injury (AKI) occurs in approximately 1-2% of patients undergoing CPB. Previous studies using activity-based protein profiling of urine identified group XV phospho...

journal_title：Clinical biochemistry

authors： Navarrete M,Wilkins JA,Chan FV,Ye B,Nickerson P,Ho J

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To investigate unusual free thyroxine (FT4) responses to T4 replacement doses in a hypothyroid patient with familial dysalbuminemic hyperthyroxinemia (FDH). METHODS:In this FDH hypothyroid patient, serum FT4 concentration by equilibrium dialysis and T4, triiodothyronine (T3), and thyroid stimulating hormone ...

journal_title：Clinical biochemistry

authors： Premachandra BN,Wortsman J,Williams IK

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:An increased level of serum vascular adhesion protein-1 (VAP-1) has been found in patients with diabetes mellitus and vascular disorders. This study examined whether serum VAP-1 levels are associated with chronic kidney disease (CKD). DESIGN AND METHODS:We included 262 subjects aged 30 and above with fastin...

journal_title：Clinical biochemistry

authors： Lin MS,Li HY,Wei JN,Lin CH,Smith DJ,Vainio J,Shih SR,Chen YH,Lin LC,Kao HL,Chuang LM,Chen MF

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Gaucher disease (GD) is caused by a deficiency of β-glucosidase (GCase), leading to accumulation of glucosylceramide (GlcC) and glucosylsphingosine (Lyso-Gb1). Lyso-Gb1 is a reliable biomarker for GD. OBJECTIVES:This study aims to develop a simple, effective and accurate method for the screening and diagn...

journal_title：Clinical biochemistry

authors： Tang C,Jia X,Tang F,Liu S,Jiang X,Zhao X,Sheng H,Peng M,Liu L,Huang Y

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Oxidative stress is considered to be a unifying link between diabetes mellitus (DM) and its complications including nephropathy. The aim of the present study was to evaluate oxidative stress status in Asian Indian patients of type 2 DM with nephropathy. DESIGN AND METHODS:Serum levels of malondialdehyde (MD...

journal_title：Clinical biochemistry

authors： Bhatia S,Shukla R,Venkata Madhu S,Kaur Gambhir J,Madhava Prabhu K

更新日期：2003-10-01 00:00:00

abstract：:Preparation of (14C) Pro labeled protocollagen and requirements for its hydroxylation by PPH was investigated. Protocollagen can be prepared by centrifugation of the biological material at 15.000 X g. Substances in current use, viz catalase, bovine serum albumin and dithiothreitol were found unnecessary under the hydr...

journal_title：Clinical biochemistry

authors： Blumenkrantz N,Asboe-Hansen G

更新日期：1976-12-01 00:00:00

abstract：:Many clinical laboratories use the Beckman Microzone electrophoretic system (Beckman Instruments Inc. Fullerton, CA 92634) for serum protein separation. Although detailed instruction is supplied in the manufacturer's manual (1) for protein separation, the effect of different sample application positions on the cellulo...

journal_title：Clinical biochemistry

authors： Chu SY,Turkington VE

更新日期：1978-12-01 00:00:00

abstract：OBJECTIVES:Superoxide dismutase (SOD) is a key antioxidant enzyme, responsible for scavenging of superoxide anion - a precursor of all reactive oxygen species (ROS). ROS are implicated in many pathologies, particularly in tumor disease. The aim of our work was to evaluate SOD isoforms' activity and protein level change...

journal_title：Clinical biochemistry

authors： Skrzycki M,Scibior D,Podsiad M,Czeczot H

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:The Golgi SNAP receptor complex member 2 (GOSR2) gene is a Golgi-associated soluble factor attachment receptor (SNARE) protein involved in intra-Golgi protein trafficking on chromosome 17q21, which is the hypertension linkage peak on the human chromosome. The aim of the present study was to assess the associ...

journal_title：Clinical biochemistry

authors： Pan S,Nakayama T,Sato N,Izumi Y,Soma M,Aoi N,Ma Y

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To assess the medical applicability of CpG methylation as molecular markers for cancer diagnosis, we established a new system to determine DNA methylation based on TaqMan PCR combined with a methyl-binding-domain polypeptide 2. DESIGN AND METHODS:We evaluated the diagnostic applicability of this approach by...

journal_title：Clinical biochemistry

authors： Kimura N,Moribe T,Iizuka N,Miura T,Tamatsukuri S,Ishitsuka H,Hamamoto Y,Oka M

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:We have comparatively evaluated respiratory burst and some steps of its signaling in human granulocytes towards different stimuli. MATERIALS AND METHODS:An alternative method to remove erythrocytes by dextran differential sedimentation was employed. Respiratory burst (RB) was assessed in a flow cytometer by...

journal_title：Clinical biochemistry

authors： Lunardi F,Lima JH,Assreuy J

更新日期：2006-01-01 00:00:00

abstract：:To design and deliver high quality, safe and effective products, manufacturers of in vitro diagnostic (IVD) products follow a structured, traceable process for controlling the uncertainty of results reported from their measurement systems. This process and its results however, are not often shared in detail with those...

journal_title：Clinical biochemistry

authors： Orzechowski A,Petrides V,Scopp R

更新日期：2018-07-01 00:00:00

abstract：:This review focusses on research performed by the author and coworkers. The absorption, turnover and excretion of cobalamin and the pathogenesis of cobalamin deficiency states are described and the laboratory tests used to diagnose these states are discussed. Topics dealt with in detail include: overall turnover, dail...

journal_title：Clinical biochemistry

authors： Gräsbeck R

更新日期：1984-04-01 00:00:00

abstract：:The use of alcohol and tobacco is prevalent among pregnant women despite the well-known adverse effects of these substances imposed on the developing fetus and immense public health education efforts. Confirmation of gestational exposures to these compounds have relied mostly on maternal self-reporting, which is often...

journal_title：Clinical biochemistry

authors： Chan D,Caprara D,Blanchette P,Klein J,Koren G

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To increase the accuracy of non-invasive diagnosis of nonalcoholic fatty liver disease (NAFLD), clinical and laboratory NAFLD indicators were integrated into a diagnostic formula. METHODS:A total of 141 patients with clinically diagnosed NAFLD and 30 healthy controls were enrolled. We collected case history,...

journal_title：Clinical biochemistry

authors： Feng G,He N,Zhou YF,Li XP,Niu C,Liu ML,Zhang KL,Li Y,Li YM,Zheng MH,Mi M

更新日期：2019-02-01 00:00:00

abstract：:The concentrations in serum of total and ionised calcium, phosphate, magnesium, albumin and alkaline phosphatase activity were measured in patients when hyperthyroid and again when euthyroid. Significant declines in the mean values of ionised calcium, phosphate and alkaline phosphatase activity and significant increas...

journal_title：Clinical biochemistry

authors： Ford HC,Crooke MJ,Murphy CE

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVES:To develop a method for the determination of succinylacetone (SA) in dried blood spots (DBS) using tandem mass spectrometry (MS/MS). METHODS:SA was extracted from DBS with an acetonitrile and water solution (80:20 by volume) containing formic acid and hydrazine hydrate (both at 0.1% by volume), and analyzed...

journal_title：Clinical biochemistry

authors： Allard P,Grenier A,Korson MS,Zytkovicz TH

更新日期：2004-11-01 00:00:00

abstract：:Stenosis is a symptom of coronary artery disease (CAD), and is caused by narrowing of arteries in the heart. Over the last several decades, medical implants such as cardiac stents have been developed to counter stenosis. Upon implantation of a stent to open up a restricted artery, narrowing of the artery can reoccur (...

journal_title：Clinical biochemistry

authors： Ravindranath RR,Romaschin A,Thompson M

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Delayed graft function (DGF) is still a major issue in kidney transplantation. Plasma and urine neutrophil gelatinase-associated lipocalin (NGAL) were evaluated in a population of kidney donors and recipients to investigate their performance to predict early renal function. DESIGN AND METHODS:Plasma (pNGAL)...

journal_title：Clinical biochemistry

authors： Buemi A,Musuamba F,Frederic S,Douhet A,De Meyer M,De Pauw L,Darius T,Kanaan N,Wallemacq P,Mourad M

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:Living donor kidney transplantation is regarded as beneficial to allograft recipients and not particularly detrimental to the donors. Recently we have documented a reduced glomerular filtration rate (GFR) in living kidney donors (LKDs). Considering kidneys as essential for l-arginine (Arg) metabolism, in the...

journal_title：Clinical biochemistry

authors： Zunić G,Tomić A,Spasić S

更新日期：2013-10-01 00:00:00

abstract：:We evaluated a method for quantifying bone isoenzyme of alkaline phosphatase (ALP) which utilizes wheat-germ lectin to precipitate this fraction. In precision studies, CVs ranged from 3.2 to 11.4% (within-day) and from 3.7 to 11.5% (day-to-day). The assay procedure was linear to 1100 U/L and was easily adapted to auto...

journal_title：Clinical biochemistry

authors： Burlina A,Plebani M,Secchiero S,Zaninotto M,Sciacovelli L

更新日期：1991-10-01 00:00:00

abstract：:The Laser Nephelometer PDQTM (Hyland Division, Travenol Laboratories Inc.) and the Abbott Bichromatic Analyser 100 (Abbott Laboratories) were compared with a radial immunodiffusion method. Seventy-eight serum specimens collected during routine blood testing were aliquoted and quantitated by the three procedures descri...

journal_title：Clinical biochemistry

authors： Bruver RM,Salkie ML

更新日期：1978-06-01 00:00:00

abstract：:57Co-cyanocobalamin is substituted for iodine labeled antigen in three commercially available solid phase radioimmunoassay kits to evaluate the extent of non-specific binding by determination of the supernatant and residual fraction of unbound ligand and thus obtain a value for corrected binding throughout the range o...

journal_title：Clinical biochemistry

authors： Carter P

更新日期：1978-06-01 00:00:00