Association between Vascular Endothelial Growth Factor Polymorphisms and Age-Related Macular Degeneration: An Updated Meta-Analysis.

abstract：Objective:Recent studies have demonstrated that miRNA-155 is involved in the occurrence and development of atherosclerosis. Furthermore, miRNA-155 has emerged as a new indirect marker for inflammation associated with adverse outcomes in oncology and cardiovascular diseases. This study investigated the correlation betwe...

journal_title：Disease markers

authors： Su Q,Yang H,Li L

更新日期：2018-06-25 00:00:00

abstract：:Alcohol abuse is one of the most common risk factor for chronic pancreatitis, but the underlying pathophysiological mechanisms remain unclear. The aim of this study was to identify genes that contribute to susceptibility or resistance for alcoholic chronic pancreatitis by screening the whole genome. Sixty-five patient...

journal_title：Disease markers

authors： Kitahara K,Kawa S,Katsuyama Y,Umemura T,Ozaki Y,Takayama M,Arakura N,Ota M

更新日期：2008-01-01 00:00:00

abstract：Materials and Methods:Relative expression of lncRNAs CARMN, LUCAT1, SMILR, and MALAT1 was tested in clinical aortic tissue and blood plasma samples from TAA and non-TAA patients using the qRT-PCR method. The Mann-Whitney U test was used to compare ΔCt values between the study groups. ROC curve analysis was performed to...

journal_title：Disease markers

authors： Patamsytė V,Žukovas G,Gečys D,Žaliaduonytė D,Jakuška P,Benetis R,Lesauskaitė V

更新日期：2020-06-17 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology, characterized by injury of the intrahepatic bile ducts that may eventually lead to cirrhosis and liver failure. Evidence suggests cardinal roles for both environmental factors and genetic susceptibilit...

journal_title：Disease markers

authors： Kumagi T,Abe M,Ikeda Y,Hiasa Y

更新日期：2010-01-01 00:00:00

abstract：:The HLA system is deeply involved in susceptibility to a variety of diseases. Relationships between HLA and diseases are of considerable interest and importance, as they provide new tools for studying the inheritance, classification, and pathogenesis of these diseases. Studies on the distribution of HLA antigens in di...

journal_title：Disease markers

authors： Jabbar AA

更新日期：1993-11-01 00:00:00

abstract：Background:In patients admitted with chest pain and suspected acute coronary syndrome (ACS), it is crucial to early identify those who are at higher risk of adverse events. The study aim was to assess the predictive value of copeptin in patients admitted to the emergency department with chest pain and nonconclusive ECG...

journal_title：Disease markers

authors： Morawiec B,Kawecki D,Przywara-Chowaniec B,Opara M,Muzyk P,Ho L,Tat LC,Gabrysiak A,Muller O,Nowalany-Kozielska E

更新日期：2018-01-24 00:00:00

abstract：Objective:To systematically evaluate the significance of squamous cell carcinoma antigen (SCC-Ag) in the prognosis of cervical cancer. Methods:Literature from Pubmed, Embase, and Cochrane Library was retrieved to collect all English literature on the correlation between SCC-Ag and cervical cancer prognosis, and the qu...

journal_title：Disease markers

authors： Liu Z,Shi H

更新日期：2019-06-02 00:00:00

abstract：:Nonenzymatic glycosylation or glycation of macromolecules, especially proteins leading to their oxidation, play an important role in diseases. Glycation of proteins primarily results in the formation of an early stage and stable Amadori-lysine product which undergo further irreversible chemical reactions to form advan...

journal_title：Disease markers

authors： Ansari NA,Moinuddin,Ali R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:We aimed to determine whether serum soluble CD30 (sCD30) could identify recipients at high risk for unfavorable early and late kidney transplant outcomes. METHODS:Serum sCD30 was measured on the day of kidney transplantation and on the 4th day posttransplant. We assessed the value of these measurements in p...

journal_title：Disease markers

authors： Trailin AV,Ostapenko TI,Nykonenko TN,Nesterenko SN,Nykonenko OS

更新日期：2017-01-01 00:00:00

abstract：:Cerebrospinal fluid (CSF) is the body fluid closest to the pathology of multiple sclerosis (MS). For many candidate biomarkers CSF is the only fluid that can be investigated. Several factors need to be standardized when sampling CSF for biomarker research: time/volume of CSF collection, sample processing/storage, and ...

journal_title：Disease markers

authors： Giovannoni G

更新日期：2006-01-01 00:00:00

abstract：:soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in three forms; suPAR(I-III), suPAR(II-III) and suPAR(I) which show different properties due to structural differences. Studies suggest that f...

journal_title：Disease markers

authors： Thunø M,Macho B,Eugen-Olsen J

更新日期：2009-01-01 00:00:00

abstract：:Some polymorphisms in genes codifying for fibrinogen have been correlated with plasma levels of this protein, and several studies reported their associations with acute cardiovascular events. In the present study, 118 subjects with unstable and stable coronary diseases were enrolled to determinate the associations amo...

journal_title：Disease markers

authors： Canseco-Avila LM,Lopez-Roblero A,Serrano-Guzman E,Aguilar-Fuentes J,Jerjes-Sanchez C,Rojas-Martinez A,Ortiz-Lopez R

更新日期：2019-07-01 00:00:00

abstract：:The aim of this study was to assess the expression of MMP-9 and TIMP-1 in cancerous tissue as well as in the serum and plasma concentrations of these proteins in patients with laryngeal cancer and compare the results to the inflammatory reaction in healthy subjects. Twenty-seven patients who were diagnosed with laryng...

journal_title：Disease markers

authors： Matulka M,Konopka A,Mroczko B,Pryczynicz A,Kemona A,Groblewska M,Sieskiewicz A,Olszewska E

更新日期：2019-04-18 00:00:00

abstract：:PIZ allele frequencies were defined by PCR amplification and hybridization using a PIZ SSO (sequence specific oligonucleotide) probe. The groups studied included 64 normal controls, 104 subjects with rheumatoid arthritis (RA) without any extra-articular features, 29 of whom had severe arthritis and 31 of whom had mild...

journal_title：Disease markers

authors： Steers G,McMahon MJ,Grennan DM,Hillarby MC

更新日期：1992-05-01 00:00:00

abstract：:Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non-Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phen...

journal_title：Disease markers

authors： Buhard O,Suraweera N,Lectard A,Duval A,Hamelin R

更新日期：2004-01-01 00:00:00

abstract：:The adenosine deaminase gene frequencies were calculated in 405 subjects randomly chosen from the Bigouden district. A rather high frequency (0.0765 +/- 0.0093) was found for the ADA2 gene. The possible effect of Celtic influences is considered. ...

journal_title：Disease markers

authors： Youinou P,Seger J,Salmon D,Jouquan J,le Menn G,Ruffie J,Salmon C

更新日期：1988-03-01 00:00:00

abstract：:Plasma from bronchial asthma patients and healthy controls was investigated for the content of lipoxygenase products. After lipid extraction using SEP-PAK C18 Cartridges, the lipoxygenase products were measured by Enzyme-Immunoassay. Elevated chemotactic B4 was found in plasma from asthmatic patients with mean value (...

journal_title：Disease markers

authors： Mansour M,Farouk N,el Maragy A,Radwan I,el-Ahmady O

更新日期：1995-03-01 00:00:00

abstract：:Several hemolytic markers are available to guide the differential diagnosis and to monitor treatment of hemolytic conditions. They include increased reticulocytes, an indicator of marrow compensatory response, elevated lactate dehydrogenase, a marker of intravascular hemolysis, reduced haptoglobin, and unconjugated hy...

journal_title：Disease markers

authors： Barcellini W,Fattizzo B

更新日期：2015-01-01 00:00:00

abstract：Objectives:To explore the impact of volume change in the fractionated tracking of stereotactic radiotherapy on the results of synchronous, respiratory tracking algorithm using CyberKnife. Methods:A total of 38 lung tumor patients receiving stereotactic radiotherapy at our center from March 2018 to October 2019 were co...

journal_title：Disease markers

authors： Li GQ,Wang Y,Qiu MJ,Yang J,Peng ZJ,Zhang S,Fang X,Yang SL

更新日期：2020-01-11 00:00:00

abstract：:Apolipoprotein E (apoE) plays an important role in lipid metabolism. Its epsilon4 allele has been consistently associated with lipoprotein disorders but its connection to myocardial infarction (MI) is controversial. Because epsilon4 frequency decreases with age we thought that the contradictory results in different st...

journal_title：Disease markers

authors： Garcés C,Maicas C,Grande R,Benavente M,Viturro E,Cano B,López D,de Oya M

更新日期：2005-01-01 00:00:00

abstract：Background:It is reported that miRNAs are aberrantly expressed in patients with pancreatic cancer. However, the diagnostic value of miRNAs in pancreatic cancer remains controversial. The meta-analysis was to access diagnostic accuracy of miRNAs in pancreatic cancer. Methods:PubMed, Scopus, Web of Science, Chinese Nati...

journal_title：Disease markers

authors： Sun X,Zhou X,Zhang Y,Zhu X,Liu H

更新日期：2018-05-15 00:00:00

abstract：Objective:To evaluate the performance of serum and urinary sCD163 concentrations as possible biomarker in systemic sclerosis (SSc). Methods:Urine and serum samples were obtained from SSc patients and age- and sex-matched controls. Serum and urinary sCD163 concentrations were measured by commercially available ELISA ki...

journal_title：Disease markers

authors： Frantz C,Pezet S,Avouac J,Allanore Y

更新日期：2018-04-01 00:00:00

abstract：:Kinesin family member 20A (KIF20A) has been recently reported to be upregulated and associated with increased invasiveness and metastasis in several malignancies. However, the role of KIF20A in colorectal cancer (CRC) is still unclear. This study is aimed at investigating the potential roles of KIF20A in the developme...

journal_title：Disease markers

authors： Zhang Q,Di J,Ji Z,Mi A,Li Q,Du X,Wang A,Wang A,Qin C

更新日期：2020-07-08 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/1202710.]. ...

journal_title：Disease markers

authors： Jiang T,Yang C,Ma L,Wu Z,Ye L,Ma X,Li H,Fan J,Yang Y

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Liver cirrhosis (LC) is the final stage of most of chronic liver diseases and is almost caused by chronic hepatitis B (CHB) in China. Liver biopsy is the reference method for the evaluation of liver cirrhosis. However, it is an invasive procedure with inherent risk. The aim of this study was to construct a n...

journal_title：Disease markers

authors： Cao Y,Hu ZD,Liu XF,Deng AM,Hu CJ

更新日期：2013-01-01 00:00:00

abstract：:IgA nephropathy is diagnosed by renal biopsy, an invasive procedure with a risk of significant complications. Noninvasive approaches are needed for possible diagnostic purposes and especially for monitoring disease activity or responses to treatment. In this pilot project, we assessed the utility of urine samples as s...

journal_title：Disease markers

authors： Neprasova M,Maixnerova D,Novak J,Reily C,Julian BA,Boron J,Novotny P,Suchanek M,Tesar V,Kacer P

更新日期：2016-01-01 00:00:00

abstract：:Our previous studies using the mass spectrum analysis provided evidence that fibrinopeptide A (FPA) could be a potential biomarker for schizophrenia diagnosis. We sought further to demonstrate that variants in the fibrinogen alpha chain gene (FGA) coded FPA might confer vulnerability to schizophrenia. 1,145 patients w...

journal_title：Disease markers

authors： Rao W,Zhou N,Zhang H,Liu R,Zhang S,Su Y,Yang G,Ma Y,Shi J,Yu Y,Yu Q

更新日期：2017-01-01 00:00:00

abstract：:Antibodies against myelin oligodendrocyte antigens have been found in the immunoreactive brain lesions of Multiple Sclerosis (MS) patients. Recently it has been proposed that these antibodies can be used as a prognostic marker in the course of disease. However, the serum levels of these autoantibodies during different...

journal_title：Disease markers

authors： Angelucci F,Mirabella M,Frisullo G,Caggiula M,Tonali PA,Batocchi AP

更新日期：2005-01-01 00:00:00

abstract：Background:We have previously shown that the deficiency of the gut enzyme intestinal alkaline phosphatase (IAP) is associated with type 2 diabetes mellitus (T2DM) in humans, and mice deficient in IAP develop the metabolic syndrome, a precipitant of T2DM and ischemic heart disease (IHD). We hypothesized that IAP deficie...

journal_title：Disease markers

authors： Malo J,Alam MJ,Shahnaz M,Kaliannan K,Chandra G,Aziz T,Sarker T,Bala M,Paul R,Saha CK,Karmakar PK,Malo MS

更新日期：2019-12-13 00:00:00

abstract：:PD1/PDL1 inhibitors have been adopted for the treatment of advanced non-small-cell lung cancer, and PDL1 expression has been investigated as a predictive biomarker for PD1/PDL1 inhibitor therapy. However, PDL1 lacks diagnostic accuracy in differentiating patients who are likely or unlikely to benefit. So, it is urgent...

journal_title：Disease markers

authors： Wu Y,Lin L,Liu X

更新日期：2020-06-09 00:00:00