Withanolides from aerial parts of Nicandra physalodes.

Abstract:

:Twenty withanolides, including previously unknown nicanlodes A-M, were isolated from aerial parts of Nicandra physalodes. Their structural elucidations were unambiguously achieved through interpretation of extensive spectroscopic data (NMR and HRMS) and by comparison with literature data. Nicanlodes A and B have an unusual aromatic amine moiety. The isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Yu MY,Zhao GT,Liu JQ,Khan A,Peng XR,Zhou L,Dong JR,Li HZ,Qiu MH

doi

10.1016/j.phytochem.2017.02.009

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

148-155

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(17)30050-X

journal_volume

137

pub_type

杂志文章
  • Multivariate approaches in plant science.

    abstract::The objective of proteomics is to get an overview of the proteins expressed at a given point in time in a given tissue and to identify the connection to the biochemical status of that tissue. Therefore sample throughput and analysis time are important issues in proteomics. The concept of proteomics is to encircle the ...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2004.04.008

    authors: Gottlieb DM,Schultz J,Bruun SW,Jacobsen S,Søndergaard I

    更新日期:2004-06-01 00:00:00

  • Biosynthesis of 20-hydroxyecdysone in plants: 3β-hydroxy-5β-cholestan-6-one as an intermediate immediately after cholesterol in Ajuga hairy roots.

    abstract::3β-Hydroxy-5β-cholestan-6-one was identified in the EtOAc extract of Ajuga hairy roots by micro-analysis using LC-MS/MS in the multiple reaction mode (MRM). Furthermore, administration of (2,2,4,4,7,7-(2)H6)- and (2,2,4,4,6,7,7-(2)H7)-cholesterols to the hairy roots followed by LC-MS/MS analysis of the EtOAc extract o...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.12.019

    authors: Fujimoto Y,Maeda I,Ohyama K,Hikiba J,Kataoka H

    更新日期:2015-03-01 00:00:00

  • Carotene derivatives in sexual communication of zygomycete fungi.

    abstract::Recognition between mating partners, early sexual morphogenesis and development are regulated by a family of beta-carotene derived signal compounds, the trisporoids, in zygomycete fungi. Mating type-specific precursors are released from the hyphae and exert their physiological effects upon compatible mating partners. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2009.07.014

    authors: Schimek C,Wöstemeyer J

    更新日期:2009-10-01 00:00:00

  • Lignans from Saururus chinensis inhibiting the transcription factor NF-kappaB.

    abstract::The sesquineolignans, saucerneol D and saucerneol E were isolated from the roots of Saururus chinensis together with four known lignans, manassantin A, manassantin B, (-)-saucerneol methyl ether, and (+)-saucernetin. Structure elucidation was based on the analysis of spectroscopic data and anti-inflammatory activity w...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(03)00391-1

    authors: Hwang BY,Lee JH,Nam JB,Hong YS,Lee JJ

    更新日期:2003-10-01 00:00:00

  • Defensive strategies in Geranium sylvaticum. Part 1: organ-specific distribution of water-soluble tannins, flavonoids and phenolic acids.

    abstract::A combination of high-resolution mass spectrometry and modern HPLC column technology, assisted by diode array detection, was used for accurate characterization of water-soluble polyphenolic compounds in the pistils, stamens, petals, sepals, stems, leaves, roots and seeds of Geranium sylvaticum. The organs contained a ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.05.013

    authors: Tuominen A,Toivonen E,Mutikainen P,Salminen JP

    更新日期:2013-11-01 00:00:00

  • Response of prostaglandin content in the red alga Gracilaria verrucosa to season and solar irradiance.

    abstract::The influence of solar irradiance and seasons on prostaglandin (PG) and arachidonic acid (AA) content in the marine red alga Gracilaria verrucosa (Huds.) Papenf. (unattached form) was investigated. PGA(2), PGE(2), PGF(2), and 15-keto-PGE(2) were isolated from the alga, quantitatively analyzed as 4-methyl-7-methoxycoum...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00321-1

    authors: Imbs AB,Vologodskaya AV,Nevshupova NV,Khotimchenko SV,Titlyanov EA

    更新日期:2001-12-01 00:00:00

  • Hepatoprotective pyranocoumarins from the stems of Clausena emarginata.

    abstract::Seven pyranocoumarins, clauemarmarins A-G, along with 6 known analogues were isolated from the stems of Clausena emarginata. Their structures were elucidated by extensive spectroscopic analyses, and the absolute stereochemistries at C-6″ of clauemarmarin B, C and D and the absolute configurations of clauemarmarin E, F...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2016.05.010

    authors: Xia HM,Li CJ,Yang JZ,Ma J,Li Y,Li L,Zhang DM

    更新日期:2016-10-01 00:00:00

  • Chemotaxonomy of the Oleaceae: iridoids as taxonomic markers.

    abstract::The distribution and biosynthesis of iridoid glucosides in the Oleaceae is reviewed and five distinct biosynthetic pathways to iridoids have been identified in the family, deoxyloganic acid apparently being a common intermediate. Likewise, the distributions of caffeoyl phenylethanoid glycosides (CPGs), i.e. verbascosi...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/s0031-9422(02)00102-4

    authors: Jensen SR,Franzyk H,Wallander E

    更新日期:2002-06-01 00:00:00

  • Kuguacins F-S, cucurbitane triterpenoids from Momordica charantia.

    abstract::Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation of fourteen cucurbitane triterpenoids, kuguacins F-S (1-14), including two pentanorcucurbitacins (6 and 7), one octanorcucurbitacin (8), and two trinorcucurbitacins (11 and 12), along with six known analogues. Their structures ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2008.10.011

    authors: Chen JC,Liu WQ,Lu L,Qiu MH,Zheng YT,Yang LM,Zhang XM,Zhou L,Li ZR

    更新日期:2009-01-01 00:00:00

  • A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.

    abstract::A new bidesmosidic triterpenoidal saponin 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->4)-alpha-L - arabinopyranosyl]-hederagenin-28-O-[alpha-L-rhamnopyranosyl- (1-->4)-beta-D- glucopyranosyl-(1-->6)-beta-D-glucopyranosyl] ester, was isolated from the roots of Symphytum officinale. The structure was a...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(95)00246-4

    authors: Mohammad FV,Noorwala M,Ahmad VU,Sener B

    更新日期:1995-09-01 00:00:00

  • Patterns of phenylpropanoids in non-inoculated and potato virus Y-inoculated leaves of transgenic tobacco plants expressing yeast-derived invertase.

    abstract::The patterns of secondary metabolites in leaves of yeast invertase-transgenic tobacco plants (Nicotiana tabacum L. cv. Samsun NN) were analyzed. Plants expressing cytosolic yeast-derived invertase (cytInv) or apoplastic (cell wall associated) yeast invertase (cwInv) showed a characteristic phytochemical phenotype comp...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00422-2

    authors: Baumert A,Mock HP,Schmidt J,Herbers K,Sonnewald U,Strack D

    更新日期:2001-03-01 00:00:00

  • Phytotoxic naphthopyranone derivatives from the coprophilous fungus Guanomyces polythrix.

    abstract::Reinvestigation of the fermentation broth and mycelium of the coprophilous fungus Guanomyces polythrix, grown in static conditions, led to the isolation of several phytotoxic compounds, including two new naphthopyranone derivatives, namely (2S, 3R)-5-hydroxy-6,8-dimethoxy-2,3-dimethyl-2,3-dihydro-4H-naphtho[2,3-b]-pyr...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00278-3

    authors: Macías M,Gamboa A,Ulloa M,Toscano RA,Mata R

    更新日期:2001-11-01 00:00:00

  • Cytotoxic xanthones from the roots of Mesua ferrea L.

    abstract::Five undescribed xanthones, 4-methoxypyranojacareubin, 4-hydroxy-3-prenylpyranoxanthone, 1-hydroxy-5,7-dimethoxyxanthone, 5-hydroxy-1,6,7-trimethoxyxanthone and 2-hydroxy-1,5-dimethoxyxanthone, together with thirty-three known xanthones were isolated from the roots of Mesua ferrea L. The structures of all isolated xan...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2018.10.008

    authors: Chukaew A,Saithong S,Chusri S,Limsuwan S,Watanapokasin R,Voravuthikunchai SP,Chakthong S

    更新日期:2019-01-01 00:00:00

  • Antibacterial compounds from Carissa lanceolata R.Br.

    abstract::The dichloromethane extract of the wood of Carissa lanceolata R.Br. (Apocynaceae) afforded the eudesmanes carissone, dehydrocarissone and carindone. This is the first account of carissone being isolated from the wood of C. lanceolata, and of carindone being isolated from this Carissa species. Dehydrocarissone has not ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00343-5

    authors: Lindsay EA,Berry Y,Jamie JF,Bremner JB

    更新日期:2000-11-01 00:00:00

  • A galloylated cyanogenic glycoside from the Australian endemic rainforest tree Elaeocarpus sericopetalus (Elaeocarpaceae).

    abstract::A cyanogenic glycoside - 6'-O-galloylsambunigrin - has been isolated from the foliage of the Australian tropical rainforest tree species Elaeocarpus sericopetalus F. Muell. (Elaeocarpaceae). This is the first formal characterisation of a cyanogenic constituent in the Elaeocarpaceae family, and only the second in the o...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.03.022

    authors: Miller RE,Stewart M,Capon RJ,Woodrow IE

    更新日期:2006-07-01 00:00:00

  • Partial purification and characterization of three ginsenoside-metabolizing beta-glucosidases from Pythium irregulare.

    abstract::The ginseng pathogen Pythium irregulare is able to selectively metabolize the 20(S) protopanaxadiol ginsenosides Rb1, Rb2, Rc, Rd, and gypenoside XVII via extracellular glycosidases, leading to the formation and partial assimilation of ginsenoside F2. Herein we have partially purified three ginsenoside-deglycosylating...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2009.09.007

    authors: Andreea Neculai M,Ivanov D,Bernards MA

    更新日期:2009-12-01 00:00:00

  • Two cationic peroxidases from cell walls of Araucaria araucana seeds.

    abstract::We have previously reported the purification and partial characterization of two cationic peroxidases from the cell walls of seeds and seedlings of the South American conifer, Araucaria araucana. In this work, we have studied the amino acid composition and NH2-terminal sequences of both enzymes. We also compare the da...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(94)00665-g

    authors: Riquelme A,Cardemil L

    更新日期:1995-05-01 00:00:00

  • Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis.

    abstract::Monoterpenoid indole alkaloids are a vast and structurally complex group of plant secondary compounds. In contrast to other groups of plant products which produce many glycosides, indole alkaloids rarely occur as glucosides. Plants of Rauvolfia serpentina accumulate ajmaline as a major alkaloid, whereas cell suspensio...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00175-8

    authors: Warzecha H,Gerasimenko I,Kutchan TM,Stöckigt J

    更新日期:2000-08-01 00:00:00

  • A "flavone-polysaccharide" redefined as a mixture of 6-methoxyluteolin penta- and hexa-O-glycosides.

    abstract::The incomplete structure proposed in 1972 for a unique "flavone-polysaccharide" compound, MF-1, from the liverwort Monoclea forsteri, has been re-examined. Rather than the proposed 8-methoxyluteolin structure with polysaccharides attached to the 7- and 4'-hydroxyls, MF-1 has been shown to be primarily a mixture of pen...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(03)00199-7

    authors: Markham KR

    更新日期:2003-07-01 00:00:00

  • Apoplastic polyesters in Arabidopsis surface tissues--a typical suberin and a particular cutin.

    abstract::Cutinized and suberized cell walls form physiological important plant-environment interfaces as they act as barriers limiting water and nutrient loss and protect from radiation and invasion by pathogens. Due to the lack of protocols for the isolation and analysis of cutin and suberin in Arabidopsis, the model plant fo...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.09.027

    authors: Franke R,Briesen I,Wojciechowski T,Faust A,Yephremov A,Nawrath C,Schreiber L

    更新日期:2005-11-01 00:00:00

  • Daffodil flowers delay senescence in cut Iris flowers.

    abstract::Visible symptoms of tepal senescence in cut Iris x hollandica (cv. Blue Magic) flowers were delayed by placing one cut daffodil flower (Narcissus pseudonarcissus, cv. Carlton) in the same vase. Addition of mucilage, exuded by daffodil stems, to the vase water had the same effect as the flowering daffodil stem. The act...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2003.12.008

    authors: van Doorn WG,Sinz A,Tomassen MM

    更新日期:2004-03-01 00:00:00

  • Transformations of testosterone and related steroids by Botrytis cinerea.

    abstract::Botrytis cinerea (strain AM235) was used to investigate the transformations of testosterone and related steroids. It was found that the position and stereochemistry of the introduced hydroxyl group, as well as the yield of products, depended on the structure of the substrate. Botrytis cinerea converts the examined sub...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00490-9

    authors: Huszcza E,Dmochowska-Gładysz J

    更新日期:2003-01-01 00:00:00

  • Relationship between chemotypic and genetic diversity of natural populations of Artemisia herba-alba Asso growing wild in Tunisia.

    abstract::A total of 80 individuals collected from eight populations growing wild in different geographic zones were considered to assess the intraspecific variability of essential oil composition, genetic diversity and population structure of Artemisia herba-alba. The essential oil composition varied significantly between popu...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2018.01.014

    authors: Younsi F,Rahali N,Mehdi S,Boussaid M,Messaoud C

    更新日期:2018-04-01 00:00:00

  • An optimized protocol for metabolome analysis in yeast using direct infusion electrospray mass spectrometry.

    abstract::A method for the global analysis of yeast intracellular metabolites, based on electrospray mass spectrometry (ES-MS), has been developed. This has involved the optimization of methods for quenching metabolism in Saccharomyces cerevisiae and extracting the metabolites for analysis by positive-ion electrospray mass spec...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00713-6

    authors: Castrillo JI,Hayes A,Mohammed S,Gaskell SJ,Oliver SG

    更新日期:2003-03-01 00:00:00

  • Antibacterial and resistance modifying activity of Rosmarinus officinalis.

    abstract::As part of a project to characterise plant-derived natural products that modulate bacterial multidrug resistance (MDR), bioassay-guided fractionation of a chloroform extract of the aerial parts of Rosmarinus officinalis led to the characterisation of the known abietane diterpenes carnosic acid (1), carnosol (2) and 12...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2004.10.009

    authors: Oluwatuyi M,Kaatz GW,Gibbons S

    更新日期:2004-12-01 00:00:00

  • Antimicrobial constituents of Scrophularia deserti.

    abstract::A study of the chemistry and antibacterial activity of Scrophularia deserti led to the isolation of eight compounds, including the metabolite 3(zeta)-hydroxy-octadeca-4(E),6(Z)-dienoic acid (1). The known compounds ajugoside (2), scropolioside B (3), 6-O-alpha-L-rhamnopyranosylcatalpol (4), buddlejoside A(8) (5), scro...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.05.011

    authors: Stavri M,Mathew KT,Gibbons S

    更新日期:2006-07-01 00:00:00

  • Lanostane triterpenoids from cultivated fruiting bodies of the wood-rot basidiomycete Ganoderma casuarinicola.

    abstract::Sixteen previously undescribed lanostane-type triterpenoids (1-16), together with fourteen known compounds, were isolated from cultivated fruiting bodies of the basidiomycete Ganoderma casuarinicola, a recently described species. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry da...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2019.112225

    authors: Isaka M,Chinthanom P,Rachtawee P,Choowong W,Choeyklin R,Thummarukcharoen T

    更新日期:2020-02-01 00:00:00

  • The biotransformation of the diterpene 2beta-hydroxy-ent-13-epi-manoyl oxide by Gibberella fujikuroi.

    abstract::Incubation of the diterpene 2beta-hydroxy-ent-13-epi-manoyl oxide with Gibberella fujikuroi afforded in good yield 2beta,6beta-dihydroxy-ent-13-epi-manoyl oxide, 2beta,12beta-dihydroxy-ent-13-epi-manoyl oxide and 2beta,20-dihydroxy-ent-13-epi-manoyl oxide, confirming that although ent-13-epi-manoyl oxide is a final me...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00436-3

    authors: Fraga BM,González P,Hernández MG,Suárez S

    更新日期:2003-01-01 00:00:00

  • Iridoid glycosides and cucurbitacin glycoside from Neopicrorhiza scrophulariiflora.

    abstract::Three iridoid glycosides, picrorosides A (1), B (2) and C (3), and a cucurbitacin glycoside, scrophoside A (4), were isolated from the rhizomes of Neopicrorhiza scrophulariiflora (Scrophulariaceae), along with two known iridoid glycosides, picrosides I (5) and II (6), and three known cucurbitacin glycosides (7-9). The...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.09.015

    authors: Kim IH,Uchiyama N,Kawahara N,Goda Y

    更新日期:2006-12-01 00:00:00

  • Steroidal glycosides and cardenolide glycosides from Asclepias fruticosa.

    abstract::Asclepias fruticosa afforded, in addition to five known pregnane glycosides and 11 known cardenolide glycosides, four new pregnane glycosides and eleven new cardenolide glycosides. Structures of these compounds were elucidated by spectroscopic methods and from chemical evidence. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(94)85029-1

    authors: Warashina T,Noro T

    更新日期:1994-09-01 00:00:00