Abstract：
:A study of the chemistry and antibacterial activity of Scrophularia deserti led to the isolation of eight compounds, including the metabolite 3(zeta)-hydroxy-octadeca-4(E),6(Z)-dienoic acid (1). The known compounds ajugoside (2), scropolioside B (3), 6-O-alpha-L-rhamnopyranosylcatalpol (4), buddlejoside A(8) (5), scrospioside A (6), laterioside (7) and 3R-1-octan-3-yl-3-O-beta-D-glucopyranoside (8) were also isolated. Compounds 1-3 exhibited moderate antibacterial activity against strains of multidrug and methicillin-resistant Staphylococcus aureus (MRSA) and a panel of rapidly growing mycobacteria with minimum inhibitory concentration (MIC) values ranging from 32 to 128 microg/ml.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Stavri M,Mathew KT,Gibbons Sdoi
10.1016/j.phytochem.2006.05.011subject
Has Abstractpub_date
2006-07-01 00:00:00pages
1530-3issue
14eissn
0031-9422issn
1873-3700pii
S0031-9422(06)00242-1journal_volume
67pub_type
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