Abstract:
:The dichloromethane extract of the wood of Carissa lanceolata R.Br. (Apocynaceae) afforded the eudesmanes carissone, dehydrocarissone and carindone. This is the first account of carissone being isolated from the wood of C. lanceolata, and of carindone being isolated from this Carissa species. Dehydrocarissone has not been isolated previously from any Carissa species. The antibacterial activity of these natural products were examined against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. All three compounds showed activity, with dehydrocarissone and carindone having a minimum inhibitory concentration less than 0.5 mg/ml against S. aureus and E. coli.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Lindsay EA,Berry Y,Jamie JF,Bremner JBdoi
10.1016/s0031-9422(00)00343-5subject
Has Abstractpub_date
2000-11-01 00:00:00pages
403-6issue
5eissn
0031-9422issn
1873-3700pii
S0031942200003435journal_volume
55pub_type
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