Antibacterial compounds from Carissa lanceolata R.Br.

Abstract:

:The dichloromethane extract of the wood of Carissa lanceolata R.Br. (Apocynaceae) afforded the eudesmanes carissone, dehydrocarissone and carindone. This is the first account of carissone being isolated from the wood of C. lanceolata, and of carindone being isolated from this Carissa species. Dehydrocarissone has not been isolated previously from any Carissa species. The antibacterial activity of these natural products were examined against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. All three compounds showed activity, with dehydrocarissone and carindone having a minimum inhibitory concentration less than 0.5 mg/ml against S. aureus and E. coli.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Lindsay EA,Berry Y,Jamie JF,Bremner JB

doi

10.1016/s0031-9422(00)00343-5

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

403-6

issue

5

eissn

0031-9422

issn

1873-3700

pii

S0031942200003435

journal_volume

55

pub_type

杂志文章
  • Phytotoxic triterpene saponins from Bellis longifolia, an endemic plant of Crete.

    abstract::In a study of 62 plant species of the Cretan flora for their phytotoxic activity, plants were extracted successively with CH2Cl2, MeOH and H2O. Phytotoxicity evaluation of the 240 extracts was performed against Lactuca sativa L. and Agrostis stolonifera L.. The MeOH extract of Bellis longifolia was the most phytotoxic...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2017.08.019

    authors: Stavropoulou MI,Angelis A,Aligiannis N,Kalpoutzakis E,Mitakou S,Duke SO,Fokialakis N

    更新日期:2017-12-01 00:00:00

  • A "flavone-polysaccharide" redefined as a mixture of 6-methoxyluteolin penta- and hexa-O-glycosides.

    abstract::The incomplete structure proposed in 1972 for a unique "flavone-polysaccharide" compound, MF-1, from the liverwort Monoclea forsteri, has been re-examined. Rather than the proposed 8-methoxyluteolin structure with polysaccharides attached to the 7- and 4'-hydroxyls, MF-1 has been shown to be primarily a mixture of pen...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(03)00199-7

    authors: Markham KR

    更新日期:2003-07-01 00:00:00

  • Lycophlegmariols A-D: cytotoxic serratene triterpenoids from the club moss Lycopodium phlegmaria L.

    abstract::Lycopodium serratene triterpenoids, along with an abietane-type diterpene were isolated from the methanol extract of club moss Lycopodium phlegmaria L. The structures of these hitherto unknown lycopodium terpenoids were elucidated on the basis of spectroscopic analysis. Pentacyclic triterpenoids, 21β-hydroxy-serrat-14...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.01.006

    authors: Wittayalai S,Sathalalai S,Thorroad S,Worawittayanon P,Ruchirawat S,Thasana N

    更新日期:2012-04-01 00:00:00

  • Annosenegalin and annogalene: two cytotoxic mono-tetrahydrofuran acetogenins from Annona senegalensis and Annona cherimolia.

    abstract::Two new cytotoxic mono-tetrahydrofuran acetongenins, annosenegalin and annogalene, have been isolated from the cytotoxic methanolic extract of Annona senegalensis and A. cherimolia seeds. Their structures were established on the basis of 1D and 2D NMR spectroscopic techniques. Annosenegalin belongs to the rare type of...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(95)00891-8

    authors: Sahpaz S,González MC,Hocquemiller R,Zafra-Polo MC,Cortes D

    更新日期:1996-05-01 00:00:00

  • Biosynthesis of the hyperforin skeleton in Hypericum calycinum cell cultures.

    abstract::Hyperforin is an important antidepressant constituent of Hypericum perforatum (St. John's wort). Cell cultures of the related species H. calycinum were found to contain the homologue adhyperforin and to a low extent hyperforin, when grown in BDS medium in the dark. Adhyperforin formation paralleled cell culture growth...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2004.11.003

    authors: Klingauf P,Beuerle T,Mellenthin A,El-Moghazy SA,Boubakir Z,Beerhues L

    更新日期:2005-01-01 00:00:00

  • Deoxyarteannuin B, dihydro-deoxyarteannuin B and trans-5-hydroxy-2-isopropenyl-5-methylhex-3-en-1-ol from Artemisia anuua.

    abstract::The amorphane sesquiterpenes, deoxyarteannuin B and dihydro-deoxyarteannuin B, were isolated from Artemisia annua and their structures mainly determined by two-dimensional NMR spectoscopic analyses. The irregular monoterpene, trans-5-hydroxy-2-isopropenyl-5-methylhex-3-en-1-ol, was also characterized in the same way, ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00358-2

    authors: Sy LK,Brown GD

    更新日期:2001-12-01 00:00:00

  • Differential tissue distribution of metabolites in Jacobaea vulgaris, Jacobaea aquatica and their crosses.

    abstract::Plants are attacked by many different herbivores. Some will consume whole leaves or roots, while others will attack specific types of tissue. Thus, insight into the metabolite profiles of different types of leaf tissues is necessary to understand plant resistance against herbivores. Jacobaea vulgaris, J. aquatica and ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.03.011

    authors: Nuringtyas TR,Choi YH,Verpoorte R,Klinkhamer PG,Leiss KA

    更新日期:2012-06-01 00:00:00

  • Diterpenoid quinones from rosemary (Rosmarinus officinalis L.).

    abstract::Two new abietane-type diterpenoid o-quinones, 7beta-methoxyabieta-8,13-diene-11,12-dione-(20,6beta)-olide (rosmaquinone A) (1) and 7alpha-methoxyabieta-8,13-diene-11,12-dione-(20,6beta)-olide (rosmaquinone B) (2), together with six known compounds were isolated from the aerial parts of Rosmarinus officinalis L. The st...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.04.041

    authors: Mahmoud AA,Al-Shihry SS,Son BW

    更新日期:2005-07-01 00:00:00

  • Cell-wall proteins from Sitka spruce xylem are selectively insolubilised during formation of dehydrogenation polymers of coniferyl alcohol.

    abstract::Extracts from the lignifying xylem of Sitka spruce that were enriched in cell-wall-associated glycoproteins contained peroxidase and oxidase activity and readily formed lignin-like water-insoluble dehydrogenation polymers (DHPs) from coniferyl alcohol (CA) when supplied with H2O2. During the formation of DHPs, the abu...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00027-9

    authors: McDougall GJ

    更新日期:2001-05-01 00:00:00

  • Flavonoids as chemotaxonomic markers in the genus Drosera.

    abstract::The botanical classification of the huge genus Drosera remains controversial since long. In the present study, the pattern of major phenolic compounds in ten Drosera species belonging to seven different subgenera and/or sections of the genus was investigated for chemotaxonomic allocation. The composition of flavonoids...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.08.017

    authors: Braunberger C,Zehl M,Conrad J,Wawrosch C,Strohbach J,Beifuss U,Krenn L

    更新日期:2015-10-01 00:00:00

  • Environmental factors influence on chemical polymorphism of the essential oils of Lychnophora ericoides.

    abstract::Lychnophora ericoides is a Brazilian medicinal plant used in folk medicine as an anti-inflammatory and analgesic agent. The essential oils from leaves of two populations with and without scent, collected at 2-month intervals during an 1-year period, were analysed by GC-MS. The results were submitted to principal compo...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.08.002

    authors: Curado MA,Oliveira CB,Jesus JG,Santos SC,Seraphin JC,Ferri PH

    更新日期:2006-11-01 00:00:00

  • Patterns of phenylpropanoids in non-inoculated and potato virus Y-inoculated leaves of transgenic tobacco plants expressing yeast-derived invertase.

    abstract::The patterns of secondary metabolites in leaves of yeast invertase-transgenic tobacco plants (Nicotiana tabacum L. cv. Samsun NN) were analyzed. Plants expressing cytosolic yeast-derived invertase (cytInv) or apoplastic (cell wall associated) yeast invertase (cwInv) showed a characteristic phytochemical phenotype comp...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00422-2

    authors: Baumert A,Mock HP,Schmidt J,Herbers K,Sonnewald U,Strack D

    更新日期:2001-03-01 00:00:00

  • Acylated sucroses and acylated quinic acids analogs from the flower buds of Prunus mume and their inhibitory effect on melanogenesis.

    abstract::The methanolic extract from the flower buds of Prunus mume, cultivated in Zhejiang Province, China, showed an inhibitory effect on melanogenesis in theophylline-stimulated B16 melanoma 4A5 cells. From the methanolic extract, five acylated sucroses, mumeoses A-E, and three acylated quinic acid analogs, 5-O-(E)-p-coumar...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.04.012

    authors: Nakamura S,Fujimoto K,Matsumoto T,Nakashima S,Ohta T,Ogawa K,Matsuda H,Yoshikawa M

    更新日期:2013-08-01 00:00:00

  • Terpenoids in transformed root culture of Tripterygium wilfordii.

    abstract::Investigation of a hairy root culture of Tripterygium wilfordii var. regelii transformed with Agrobacterium rhizogenes resulted in the isolation of new diterpenoid and sesquiterpenoid together with known triterpenoids. These structures were determined by spectroscopic analyses. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(98)00300-8

    authors: Nakano K,Yoshida C,Furukawa W,Takaishi Y,Shishido K

    更新日期:1998-11-20 00:00:00

  • A comprehensive metabolite profiling of Isatis tinctoria leaf extracts.

    abstract::A broad-based characterisation of a pharmacologically active dichloromethane extract from Isatis tinctoria leaves was carried out. For a comprehensive picture we also included the polar constituents of I. tinctoria (MeOH extract) and for comparative purposes, the taxonomically closely related plant I. indigotica. Diod...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2009.04.019

    authors: Mohn T,Plitzko I,Hamburger M

    更新日期:2009-05-01 00:00:00

  • Evolution of alkaloid biosynthesis in the genus Narcissus.

    abstract::In an attempt to reveal the relationships between alkaloid biosynthesis and phylogeny, we investigated by GC-MS the alkaloid patterns of 22 species and 3 hybrids (from 45 locations) from seven main sections of the genus Narcissus (Amaryllidaceae). The results indicate that the first alkaloids to evolve in the genus Na...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.11.002

    authors: Berkov S,Martínez-Francés V,Bastida J,Codina C,Ríos S

    更新日期:2014-03-01 00:00:00

  • Iridal glycosides from Iris spuria (Zeal), cultivated in Egypt.

    abstract::Fractionation of a methanol extract obtained from rhizomes of I. spuria (Zeal) resulted in the isolation of seven iridalglycosides 5a,b, 6a-c, 7, 8. The structures of the aglycons and the position of the glycosidic bonds were elucidated by spectroscopic analyses. The nature of the sugar moieties was determined as gluc...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00110-3

    authors: Marner FJ,Singab AN,Al-Azizi MM,El-Emary NA,Schäfer M

    更新日期:2002-06-01 00:00:00

  • Flavanoids from Caesalpinia pulcherrima.

    abstract::Two new flavanoids, 5,7-dimethoxy-3',4'-methylenedioxyflavanone and isobonducellin along with 2'-hydroxy-2,3,4',6'-tetramethoxychalcone, 5,7-dimethoxyflavone and bonducellin were isolated from the aerial parts of Caesalpinia pulcherrima. The structures of the compounds were settled mainly by interpretation of their 1D...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(03)00325-x

    authors: Srinivas KV,Koteswara Rao Y,Mahender I,Das B,Rama Krishna KV,Hara Kishore K,Murty US

    更新日期:2003-08-01 00:00:00

  • Antiviral benzofurans from Eupatorium chinense.

    abstract::Eleven benzofuran dimers, (+)-dieupachinins A-E, (-)-dieupachinins A-E and dieupachinin F, a benzofuran trimer trieupachinin A, as well as seven known compounds were isolated from the roots of Eupatorium chinense. The enantiomers of racemates dieupachinins A-E were separated by chiral HPLC. The structures with absolut...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.11.013

    authors: Wang WJ,Wang L,Liu Z,Jiang RW,Liu ZW,Li MM,Zhang QW,Dai Y,Li YL,Zhang XQ,Ye WC

    更新日期:2016-02-01 00:00:00

  • Structure elucidation and hepatotoxicity evaluation against HepG2 human cells of neo-clerodane diterpenes from Teucrium polium L.

    abstract::Seven neo-clerodanes (teupolins VI-XII) and eleven known compounds were isolated and characterized from leaf extracts of Teucrium polium L., a medicinal plant used in traditional and herbal medicine for its hypolipidemic, hypoglycemic, antioxidant and antiproliferative properties. The structures of these compounds wer...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.07.006

    authors: Fiorentino A,D'Abrosca B,Pacifico S,Scognamiglio M,D'Angelo G,Gallicchio M,Chambery A,Monaco P

    更新日期:2011-11-01 00:00:00

  • Triterpenoid glycosides from Adina rubella.

    abstract::Two new triterpenoid glycosides, quinovic acid-3 beta-O-beta-D- glucopyranosyl-(1-->4)-alpha-L-rhamnopyranoside and quinovic acid-3 beta-O-beta-D-glucopyranosyl-(1-->3)-beta-D-fucopyranoside (named rubelloside A and B, respectively), were isolated from roots of Adina rubella. Their structures were elucidated by spectr...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(95)00119-r

    authors: Fang SY,He ZS,Gao JH,Wang P

    更新日期:1995-07-01 00:00:00

  • Mangiterpenes A-C and 2',3'-seco-manginoid C, four sesquiterpene/monoterpene-shikimate-conjugated spirocyclic meroterpenoids from Guignardia mangiferae.

    abstract::Mangiterpenes A-C and 2',3'-seco-manginoid C, four undescribed sesquiterpene/monoterpene-shikimate-conjugated meroterpenoids with spiro ring systems, were isolated from Guignardia mangiferae. The structures and absolute configurations of these compounds were established by comprehensive spectroscopic analyses and elec...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2019.05.018

    authors: Chen K,Chen C,Guo J,Sun W,Liu J,Yang J,Liu X,Wang J,Luo Z,Zhu H,Zhang Y

    更新日期:2019-08-01 00:00:00

  • Acylated cyanidin 3-sambubioside-5-glucosides in three garden plants of the Cruciferae.

    abstract::Seven acylated cyanidin 3-sambubioside-5-glucosides were isolated from the flowers of three garden plants in the Cruciferae. Specifically, four pigments were isolated from Lobularia maritima (L.) Desv., together with a known pigment, as well as, three pigments from Lunaria annua L., and two known pigments from Cheiran...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2006.05.001

    authors: Tatsuzawa F,Saito N,Shinoda K,Shigihara A,Honda T

    更新日期:2006-06-01 00:00:00

  • Integration of non-targeted metabolomics and automated determination of elemental compositions for comprehensive alkaloid profiling in plants.

    abstract::Plants produce a large array of specialized metabolites to protect themselves. Among these allelochemicals, alkaloids display highly diverse and complex structures that are directly related to their biological activities. Plant alkaloid profiling traditionally requires extensive and time-consuming sample preparation a...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2018.06.011

    authors: Vanderplanck M,Glauser G

    更新日期:2018-10-01 00:00:00

  • Ester-type cephalotaxus alkaloids from Cephalotaxus harringtonia var. drupacea.

    abstract::Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was eva...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(96)00574-2

    authors: Takano I,Yasuda I,Nishijima M,Yanagi Y,Takeya K,Itokawa H

    更新日期:1997-02-01 00:00:00

  • A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus.

    abstract::The anticancer agents vinblastine and vincristine are bisindole alkaloids derived from coupling vindoline and catharanthine, monoterpenoid indole alkaloids produced exclusively by the Madagascar periwinkle (Catharanthus roseus). Industrial production of vinblastine and vincristine currently relies on isolation from C....

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.07.001

    authors: Liscombe DK,O'Connor SE

    更新日期:2011-11-01 00:00:00

  • Allosteric substrate inhibition of Arabidopsis NAD-dependent malic enzyme 1 is released by fumarate.

    abstract::Plant mitochondria can use L-malate and fumarate, which accumulate in large levels, as respiratory substrates. In part, this property is due to the presence of NAD-dependent malic enzymes (NAD-ME) with particular biochemical characteristics. Arabidopsis NAD-ME1 exhibits a non-hyperbolic behavior for the substrate L-ma...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.11.009

    authors: Tronconi MA,Wheeler MC,Martinatto A,Zubimendi JP,Andreo CS,Drincovich MF

    更新日期:2015-03-01 00:00:00

  • 3 alpha-hydroxy-oleanane-type triterpene glycosyl esters from leaves of Acanthopanax spinosus.

    abstract::Three novel 3 alpha-hydroxy-oleanane-type triterpene oligoglycosyl esters, spinoside C1, C4 and C5, were isolated from the leaves of Acanthopanax spinosus. The structures were established to be 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl esters of 3 alpha, 29-dihydroxy-olean...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)90853-7

    authors: Miyakoshi M,Ida Y,Isoda S,Shoji J

    更新日期:1993-12-01 00:00:00

  • Bioactive terpenoids from sunflower leaves cv. Peredovick.

    abstract::The CH(2)Cl(2) extract of dried leaves of Helianthus annuus L. cv. Peredovick(R) has yielded, in addition to the known sesquiterpene lactones annuolide E and leptocarpin, and the sesquiterpenes heliannuols A, C, D, F, G, H, I, the new bisnorsesquiterpene, annuionone E, and the new sesquiterpenes heliannuol L, helibisa...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00370-9

    authors: Macías FA,Torres A,Galindo JL,Varela RM,Alvarez JA,Molinillo JM

    更新日期:2002-11-01 00:00:00

  • Interconverting flavonostilbenes with antibacterial activity from Sophora alopecuroides.

    abstract::Five flavonostilbenes (alopecurones H, I, J, K and L) and five known ones were isolated from roots of Sophora alopecuroides, in addition to ten other phenolic compounds. A non-enzymatic interconversion of the lavandulyl-substituted flavonostilbenes was observed among alopecurones A, H, I, and K through a Wessely-Moser...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.02.022

    authors: Wan CX,Luo JG,Ren XP,Kong LY

    更新日期:2015-08-01 00:00:00