Antiviral benzofurans from Eupatorium chinense.

Abstract:

:Eleven benzofuran dimers, (+)-dieupachinins A-E, (-)-dieupachinins A-E and dieupachinin F, a benzofuran trimer trieupachinin A, as well as seven known compounds were isolated from the roots of Eupatorium chinense. The enantiomers of racemates dieupachinins A-E were separated by chiral HPLC. The structures with absolute configurations were elucidated on the basis of spectroscopic data, X-ray diffraction analysis, and circular dichroism experiments. The isolated compounds were evaluated for their in vitro antiviral activities against respiratory syncytial virus (RSV).

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Wang WJ,Wang L,Liu Z,Jiang RW,Liu ZW,Li MM,Zhang QW,Dai Y,Li YL,Zhang XQ,Ye WC

doi

10.1016/j.phytochem.2015.11.013

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

238-245

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(15)30114-X

journal_volume

122

pub_type

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