Dihydroagarofuran alkaloid and triterpenes from Maytenus heterophylla and Maytenus arbutifolia.

Abstract:

:The antimicrobially active EtOH extracts of Maytenus heterophylla yielded a new dihydroagarofuran alkaloid,1beta-acetoxy-9alpha-benzoyloxy-2beta,6alpha-dinicotinoyloxy-beta-dihydroagarofuran, together with the known compounds beta-amyrin, maytenfolic acid, 3alpha-hydroxy-2-oxofriedelane-20alpha-carboxylic acid, lup-20(29)-ene-1beta,3beta-diol, (-)-4'-methylepigallocatechin, and (-)-epicatechin. In addition, beta-amyrin, (-)-epicatechin and (-)-4'-methylepigallocatechin were isolated from Maytenus arbutifolia. The structure elucidation of the isolated compounds was based primarily on 1D and 2D NMR analyses, including HMQC, HMBC, and NOESY correlations. Maytenfolic acid showed moderate antimicrobial activity by inhibiting the growth of Candida albicans, Cryptococcus neoformans, Staphylococcus aureus and Pseudomonas aeruginosa.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Orabi KY,Al-Qasoumi SI,El-Olemy MM,Mossa JS,Muhammad I

doi

10.1016/s0031-9422(01)00277-1

subject

Has Abstract

pub_date

2001-10-01 00:00:00

pages

475-80

issue

3

eissn

0031-9422

issn

1873-3700

pii

S0031942201002771

journal_volume

58

pub_type

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