Cadinane sesquiterpenes from the mushroom Lyophyllum transforme.

Abstract:

:Two rare cadinane-type sesquiterpenes, lyophyllone A (1) and lyophyllanetriol A (2), were isolated from the mushroom Lyophyllum transforme. The structures were elucidated on the basis of exhaustive NMR techniques, together with MS, UV-Vis and molecular modelling. The absolute configuration of lyophyllone A was determined by ab initio theoretical CD calculation performed by Density Functional Theory (DFT) using the B3PW91/6-31G(d,p) basis set. The experimental CD were found to be in good agreement with the corresponding population-weighted theoretical CD spectra, allowing for the determination of the absolute stereochemistry of the compound.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Clericuzio M,Negri R,Cossi M,Gilardoni G,Gozzini D,Vidari G

doi

10.1016/j.phytochem.2013.03.019

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

192-8

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(13)00115-5

journal_volume

93

pub_type

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