Abstract:
:An investigation into the antibacterial properties of Hypericum foliosum Aiton. (Guttiferae) has led to the isolation of a new bioactive acylphloroglucinol natural product which by NMR spectroscopy and mass spectrometry was characterised as 1,3,5-trihydroxy-6-[2''',3'''-epoxy-3'''-methyl-butyl]-2-[2''-methyl-butanoyl]-4-[3'-methyl-2''-butenyl]-benzene and is described here for the first time. This metabolite was evaluated against a panel of multidrug-resistant strains of Staphylococcus aureus and minimum inhibitory values ranged from 16 to 32 microg/ml.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Gibbons S,Moser E,Hausmann S,Stavri M,Smith E,Clennett Cdoi
10.1016/j.phytochem.2005.04.024subject
Has Abstractpub_date
2005-06-01 00:00:00pages
1472-5issue
12eissn
0031-9422issn
1873-3700pii
S0031-9422(05)00188-3journal_volume
66pub_type
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