Acylated triterpene saponins from Silene jenisseensis.

Abstract:

:From the roots of Silene jenisseensis a new trans-p-methoxycinnamoyl triterpene saponin has been isolated along with its cis-p-methoxycinnamoyl isomer as an inseparable mixture. Their structures were established by chemical means and spectroscopic methods including 1D- and 2D-homonuclear and heteronuclear correlation NMR spectroscopy as 3-O-[beta-D-galactopyranosyl-(1 --> 2)-beta-D-glucuronopyranosyl]-28-O-[beta-D-glucopyranosyl-(1 --> 2)-alpha-L-rhamnopyranosyl- (1 --> 2)-beta-D-4-O-trans-p-methoxycinnamoyl-fucopyranosyl] quillaic acid and its cis-isomer, respectively. They did not show any activity in the in vitro chemoluminescence granulocytes assay, but exhibited only a weak inhibitory effect in the cyclooxygenase inhibition assay.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Lacaille-Dubois MA,Hanquet B,Cui ZH,Lou ZC,Wagner H

doi

10.1016/0031-9422(95)00222-s

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

509-14

issue

2

eissn

0031-9422

issn

1873-3700

pii

003194229500222S

journal_volume

40

pub_type

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