Abstract:
:Five labdane diterpenoids, (3-5), zambesiacolactone A (7) and zambesiacolactone B (8), were isolated from the seeds of Aframomum zambesiacum (Baker) K. Schum., along with five known labdanes and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Their antiplasmodial activity was evaluated in vitro against Plasmodium falciparum. Compound 3 was the most active with an IC(50) value of 4.97 microM.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Kenmogne M,Prost E,Harakat D,Jacquier MJ,Frédérich M,Sondengam LB,Zèches M,Waffo-Téguo Pdoi
10.1016/j.phytochem.2005.10.015subject
Has Abstractpub_date
2006-03-01 00:00:00pages
433-8issue
5eissn
0031-9422issn
1873-3700pii
S0031-9422(05)00545-5journal_volume
67pub_type
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