Five labdane diterpenoids from the seeds of Aframomum zambesiacum.


:Five labdane diterpenoids, (3-5), zambesiacolactone A (7) and zambesiacolactone B (8), were isolated from the seeds of Aframomum zambesiacum (Baker) K. Schum., along with five known labdanes and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Their antiplasmodial activity was evaluated in vitro against Plasmodium falciparum. Compound 3 was the most active with an IC(50) value of 4.97 microM.






Kenmogne M,Prost E,Harakat D,Jacquier MJ,Frédérich M,Sondengam LB,Zèches M,Waffo-Téguo P




Has Abstract


2006-03-01 00:00:00














  • Conversions of deoxyradicinin to radicinin and of radicinin to 3-epi-radicinin in the phytopathogenic fungus Bipolaris coicis.

    abstract::Radicinin is a phytotoxic and antibiotic metabolite produced by some phytopathogenic fungi. Precursor administration and cell-free experiments with deoxyradicinin and radicinin were carried out in Bipolaris coicis H13-3. When deoxyradicinin was administered to the fungus, radicinin and 3-epi-radicinin formed. When rad...


    pub_type: 杂志文章


    authors: Suzuki M,Sakuno E,Ishihara A,Tamura J,Nakajima H

    更新日期:2012-03-01 00:00:00

  • Scrokoelziside A, a triterpene glycoside from Scrophularia koelzii.

    abstract::Scrokoelziside A, isolated from the aerial parts of Scrophularia koelzii was shown to be 3-O-([alpha-L-rhamnopyranosyl-(1-->3), beta-D-glucopyranosyl-(1-->2)]-beta-D-fucopyranosyl-(1-->4)-beta-D- glucopyranosyl]-13 beta,28-epoxyolean-11-en-23-ol, on the basis one- and two-dimensional NMR homo- and hetero-nuclear spect...


    pub_type: 杂志文章


    authors: Bhandari SP,Roy R,Agrawal PK,Garg HS

    更新日期:1996-02-01 00:00:00

  • Polyketide synthases of bacterial symbionts in sponges--evolution-based applications in natural products research.

    abstract::Marine sponges are an unusually rich source of bioactive natural products with clinical potential. They also often harbor rich communities of symbiotic bacteria that have often been suspected as the true producers of sponge-derived compounds. To date, these bacteria can in most cases not be cultivated, but culture-ind...


    pub_type: 杂志文章,评审


    authors: Hochmuth T,Piel J

    更新日期:2009-10-01 00:00:00

  • Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit.

    abstract::Two sulfur-containing compounds, (S)-2-amino-5-((R)-1-carboxy-2-((E)-3-(4-hydroxy-3-methoxyphenyl)allylthio)ethyl-amino)-5-oxopentanoic acid (1) and (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((E)-3-(4-hydroxyphenyl)allylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid (2), and one 1H-pyrrole-2-carboxylic acid deriva...


    pub_type: 杂志文章


    authors: Zheng ZP,Ma J,Cheng KW,Chao J,Zhu Q,Chang RC,Zhao M,Lin ZX,Wang M

    更新日期:2010-12-01 00:00:00

  • A benzoic acid glycoside from Geniostoma antherotrichum.

    abstract::Fractionation of an HIV-inhibitory organic extract of Geniostoma antherotrichum afforded a glycoside derivative, which has been characterized as 2-hydroxy-3-O-beta-D-glucopyranosyl-benzoic acid (1) on the basis of spectral analyses. The HIV-inhibitory activity of the extract was traced to polymeric tannins, while 1 wa...


    pub_type: 杂志文章


    authors: Rashid MA,Gustafson KR,Cardellina JH 2nd,Boyd MR

    更新日期:1996-03-01 00:00:00

  • An 8-hydroxylated external flavone and its 8-O-glucoside from Becium grandiflorum.

    abstract::The major vacuolar flavonoid of a greenhouse-grown plant of Becium grandiflorum has been identified as the 8-O-glucoside of isothymusin (5,8,4'-trihydroxy-6,7-dimethoxyflavone), while the major external flavonoids in the diethyl ether surface wash of the same plant are found to be isothymusin and cirsimaritin (5,4'-di...


    pub_type: 杂志文章


    authors: Grayer RJ,Veitch NC

    更新日期:1998-03-01 00:00:00

  • A variable loop involved in the substrate selectivity of pinoresinol/lariciresinol reductase from Camellia sinensis.

    abstract::Pinoresinol/lariciresinol reductase (PLR), an NADPH-dependent reductase that catalyzes the sequential reduction of pinoresinol into secoisolariciresinol via Lariciresinol, can lead to the structural and stereochemical diversity of lignans. The relationship between substrate-selective reaction of PLR and sequence homol...


    pub_type: 杂志文章


    authors: Wu Y,Xing D,Ma G,Dai X,Gao L,Xia T

    更新日期:2019-06-01 00:00:00

  • African Cucurbita pepo L.: properties of seed and variability in fatty acid composition of seed oil.

    abstract::Pumpkin (Cucurbita pepo) seeds are used locally in Eritrea to treat tapeworm. Seeds were found to be rich in oil (approximately 35%), protein (38%), alpha-tocoferols (3 mg/100 g) and carbohydrate content (approximately 37%). The physico-chemical properties and fatty acid composition of the seed oil were examined. The ...


    pub_type: 杂志文章


    authors: Younis YM,Ghirmay S,al-Shihry SS

    更新日期:2000-05-01 00:00:00

  • Antibacterial bromophenols from the marine red alga Rhodomela confervoides.

    abstract::Two bromophenols, together with three known compounds, were isolated from the methanolic extract of the marine alga, Rhodomela confervoides. By means of MS and NMR spectroscopic analyses, they were identified as 3-bromo-4-[2,3-dibromo-4,5-dihydroxyphenyl] methyl-5-(hydroxymethyl) 1,2-benzenediol (1) and 3-bromo-4-[2,3...


    pub_type: 杂志文章


    authors: Xu N,Fan X,Yan X,Li X,Niu R,Tseng CK

    更新日期:2003-04-01 00:00:00

  • Hydroquinone: O-glucosyltransferase from cultivated Rauvolfia cells: enrichment and partial amino acid sequences.

    abstract::Plant cell suspension cultures of Rauvolfia are able to produce a high amount of arbutin by glucosylation of exogenously added hydroquinone. A four step purification procedure using anion exchange, hydrophobic interaction, hydroxyapatite-chromatography and chromatofocusing delivered in a yield of 0.5%, an approximatel...


    pub_type: 杂志文章


    authors: Arend J,Warzecha H,Stöckigt J

    更新日期:2000-01-01 00:00:00

  • Triterpene saponins from Scabiosa rotata.

    abstract::Four new allose-containing triterpenoid saponosides, scabriosides A, B, C and D were isolated from the roots of Scabiosa rotata. Their structures were established as 3-O-beta-D-xylopyranosyl-28-O-[beta-D-allopyranosyl (1-->6)-beta-D-glucopyranosyl]-pomolic acid, 3-O-[alpha-L-rhamnopyranosyl (1-->2)-beta-D-xylopyranosy...


    pub_type: 杂志文章


    authors: Baykal T,Panayir T,Tasdemir D,Sticher O,Calis I

    更新日期:1998-07-01 00:00:00

  • Triterpenoids from the stems and leaves of Schisandra incarnata.

    abstract::Six undescribed triterpenoids, schincarins A‒F, categorized as the preschisanartane (schincarin A), 3,4-secocycloartane (schincarins B‒D), 3,4; 9,10-disecocycloartane (schincarin E), and 3,4-secolanostane (schincarin F) classes, along with twelve known analogues, were obtained from the stems and leaves of Schisandra i...


    pub_type: 杂志文章


    authors: Zhou M,Peng X,Zhou J,Liu Y,Meng X,Ruan H

    更新日期:2020-09-01 00:00:00

  • Main glucosidase conversion products of the gluco-alkaloids dolichantoside and palicoside.

    abstract::The enzymatic glucose cleavage of palicoside revealed the biosynthetic pathway to akagerine, whereas the conversion of dolichantoside led to a new quaternary heteroyohimbine alkaloid named N(b)-methyl-21-beta-hydroxy-mayumbine. The hypothetical models of reactions occurring after the conversion of both substrates are ...


    pub_type: 杂志文章


    authors: Brandt V,Tits M,Penelle J,Frédérich M,Angenot L

    更新日期:2001-07-01 00:00:00

  • A benzoquinone and flavonoids from Cyperus alopecuroides.

    abstract::A benzoquinone, named alopecuquinone, was isolated from the ethanol extract of the inflorescences of Cyperus alopecuroides. Its structure was primarily elucidated by spectroscopic analysis including 1H, 13C NMR, APT, HMQC, 1H-1H COSY and CIMS. The known flavonoids, vicenin 2, orientin, diosmetin, quercetin 3,3'-dimeth...


    pub_type: 杂志文章


    authors: Nassar MI,Abdel-Razik AF,El-Khrisy Eel-D,Dawidar AA,Bystrom A,Mabry TJ

    更新日期:2002-06-01 00:00:00

  • A potent bidirectional promoter from the monocot cereal Eleusine coracana.

    abstract::Ragi bifunctional α-amylase-trypsin inhibitor (RBI) of Eleusine coracana (L.) Gaertn. (finger millet) simultaneously inhibits α-amylase and trypsin. In continuation of previous work on the cloning, expression and characterization of RBI, a bidirectional promoter from finger millet was explored on the basis of experime...


    pub_type: 杂志文章


    authors: Sen S,Dutta SK

    更新日期:2016-09-01 00:00:00

  • Thelephantins D-H: five p-terphenyl derivatives from the inedible mushroom Thelephora aurantiotincta.

    abstract::Five p-terphenyl derivatives named thelephantins D-H (1-5) together with nine known compounds, thelephantins A-C (6-8), ganbajunin E (9), p-hydroxylbenzoic acid (10), ganbajunin C (11), thelephorin A (12), 2-O-methylatromentin (13) and atromentin (14), were isolated from the methanolic extract of fruit bodies of the T...


    pub_type: 杂志文章


    authors: Ngoc Quang D,Hashimoto T,Hitaka Y,Tanaka M,Nukada M,Yamamoto I,Asakawa Y

    更新日期:2003-08-01 00:00:00

  • Chemical interactions between plants in Mediterranean vegetation: the influence of selected plant extracts on Aegilops geniculata metabolome.

    abstract::Allelopathy is the chemical mediated communication among plants. While on one hand there is growing interest in the field, on the other hand it is still debated as doubts exist at different levels. A number of compounds have been reported for their ability to influence plant growth, but the existence of this phenomeno...


    pub_type: 杂志文章


    authors: Scognamiglio M,Fiumano V,D'Abrosca B,Esposito A,Choi YH,Verpoorte R,Fiorentino A

    更新日期:2014-10-01 00:00:00

  • Polyamine synthesis in plants. Purification and properties of amidinotransferase from soybean (Glycine max) axes.

    abstract::Three-day-old soybean (Glycine max) seedlings were exposed to 0.4 M sorbitol solution for 4 h to induce amidinotransferase activity, with the corresponding enzyme being purified to homogeneity by chromatographic separation on DEAE-Sephacel, Sephacryl S-300 and L-arginine Sepharose 4B. The purified enzyme used L-argini...


    pub_type: 杂志文章


    authors: Lee GT,Kim WJ,Cho YD

    更新日期:2002-12-01 00:00:00

  • Glutathione reductase activity and isoforms in leaves and roots of wheat plants subjected to cadmium stress.

    abstract::The behavior of glutathione reductase (GR, EC activity and isoforms were analyzed in wheat (Triticum aestivum L.) leaves and roots exposed to a chronic treatment with a toxic cadmium (Cd) concentration. A significant growth inhibition (up to 55%) was found in leaves at 7, 14 and 21 days, whereas roots were af...


    pub_type: 杂志文章


    authors: Yannarelli GG,Fernández-Alvarez AJ,Santa-Cruz DM,Tomaro ML

    更新日期:2007-02-01 00:00:00

  • Pithedulosides A-G, oleanane glycosides from Pithecellobium dulce.

    abstract::Seven saponins named pithedulosides A-G were isolated from the seeds of Pithecellobium dulce. Their structures were established through spectral analyses as echinocystic acid 3-O-alpha-L-arabinopyranosyl-(1-->6)-beta-D-glucopyranoside, echinocystic acid and oleanolic acid 3-O-alpha-L-arabinopyranosyl- (1-->2)-alpha-L-...


    pub_type: 杂志文章


    authors: Nigam SK,Gopal M,Uddin R,Yoshikawa K,Kawamoto M,Arihara S

    更新日期:1997-04-01 00:00:00

  • Phytoalexins from Brassicaceae: news from the front.

    abstract::The chemical structures, syntheses, metabolism and biological activities of the cruciferous phytoalexins discovered to date, with particular focus on the latest results dealing with their biosynthesis and detoxification are reviewed. ...


    pub_type: 杂志文章,评审


    authors: Pedras MS,Yaya EE

    更新日期:2010-08-01 00:00:00

  • Antimicrobial constituents of Scrophularia deserti.

    abstract::A study of the chemistry and antibacterial activity of Scrophularia deserti led to the isolation of eight compounds, including the metabolite 3(zeta)-hydroxy-octadeca-4(E),6(Z)-dienoic acid (1). The known compounds ajugoside (2), scropolioside B (3), 6-O-alpha-L-rhamnopyranosylcatalpol (4), buddlejoside A(8) (5), scro...


    pub_type: 杂志文章


    authors: Stavri M,Mathew KT,Gibbons S

    更新日期:2006-07-01 00:00:00

  • Phytoalexins from Thlaspi arvense, a wild crucifer resistant to virulent Leptosphaeria maculans: structures, syntheses and antifungal activity.

    abstract::Phytoalexins are inducible chemical defenses produced by plants in response to diverse forms of stress, including microbial attack. Our search for phytoalexins from cruciferous plants resistant to economically important fungal diseases led us to examine stinkweed or pennycress (Thlaspi arvense), a potential source of ...


    pub_type: 杂志文章


    authors: Pedras MS,Chumala PB,Suchy M

    更新日期:2003-11-01 00:00:00

  • Purification and characterization of a Ca(2+)-dependent protein kinase from sandalwood (Santalum album L.): evidence for Ca(2+)-induced conformational changes.

    abstract::An early development-specific soluble 55 kDa Ca(2+)-dependent protein kinase has been purified to homogeneity from sandalwood somatic embryos and biochemically characterized. The purified enzyme, swCDPK, resolved into a single band on 10% polyacrylamide gels, both under denaturing and non-denaturing conditions. swCDPK...


    pub_type: 杂志文章


    authors: Anil VS,Sankara Rao K

    更新日期:2001-09-01 00:00:00

  • Oxylipins in the spikemoss Selaginella martensii: Detection of divinyl ethers, 12-oxophytodienoic acid and related cyclopentenones.

    abstract::Green tissues of spikemoss Selaginella martensii Spring possessed the complex oxylipins patterns. Major oxylipins were the products of linoleic and α-linolenic acids metabolism via the sequential action of 13-lipoxygenase and divinyl ether synthase (DES) or allene oxide synthase (AOS). AOS products were represented by...


    pub_type: 杂志文章


    authors: Ogorodnikova AV,Mukhitova FK,Grechkin AN

    更新日期:2015-10-01 00:00:00

  • Evolution of pyrrolizidine alkaloids in Phalaenopsis orchids and other monocotyledons: identification of deoxyhypusine synthase, homospermidine synthase and related pseudogenes.

    abstract::In order to study the evolution of pathways of plant secondary metabolism, we use the biosynthesis of pyrrolizidine alkaloids (PAs) as a model system. PAs are regarded as part of the plant's constitutive defense against herbivores. Homospermidine synthase (HSS) is the first specific enzyme of PA biosynthesis. The gene...


    pub_type: 杂志文章


    authors: Nurhayati N,Gondé D,Ober D

    更新日期:2009-03-01 00:00:00

  • Anti-inflammatory triterpene saponins of Pithecellobium dulce: characterization of an echinocystic acid bisdesmoside.

    abstract::A new bisdesmodic triterpenoid saponin, dulcin was isolated from the seeds of Pithecellobium dulce and was identified as 3-O-[beta-D-glucopyranosyl (1-->2)-alpha-L-arabinopyranosyl]- 28-O-[beta-D-xylopyranosyl (1-->6)-beta-D-glucopyranosyl]-echinocystic acid. The known oleanolic acid saponin PE, oleanolic acid 3-O-bet...


    pub_type: 杂志文章


    authors: Sahu NP,Mahato SB

    更新日期:1994-11-01 00:00:00

  • Acetylated glucuronide triterpene bidesmosidic saponins from Symplocos glomerata.

    abstract::Nine new bidesmosidic 3-O-glucuronide oleanane triterpenoid saponins were isolated from the stem bark of Symplocos glomerata King along with two known saponins, salsoloside C and copteroside E, and two major lignans, (-)-pinoresinol and (-)-pinoresinol-4'-O-beta-D-glucopyranoside. The structures of the new saponins we...


    pub_type: 杂志文章


    authors: Waffo-Téguo P,Voutquenne L,Thoison O,Dumontet V,Nguyen VH,Lavaud C

    更新日期:2004-03-01 00:00:00

  • The role of germacrene D as a precursor in sesquiterpene biosynthesis: investigations of acid catalyzed, photochemically and thermally induced rearrangements.

    abstract::Germacrene D is considered as a precursor of many sesquiterpene hydrocarbons. We have investigated the acid catalyzed as well as the photochemically and thermally induced rearrangement processes of germacrene D isolated from several Solidago species, which contain both enantiomers of germacrene D. Enantiomeric mixture...


    pub_type: 杂志文章


    authors: Bülow N,Konig WA

    更新日期:2000-09-01 00:00:00

  • 14-Decarboxyquinovic and quinovic acid glycosides from Zygophyllum album.

    abstract::Further investigation of the leaves and stems of Zygophyllum album afforded four triterpene glycosides which were characterized as 14-decarboxyquinovic acid-3 beta-O-beta-D-quinovopyranosyl (1-->4)-quinovopyranoside, quinovic acid 28-O-beta-D-glucopyranosyl (2-->1)beta-D-glucopyranosyl ester, quinovic acid 27-O-beta-D...


    pub_type: 杂志文章


    authors: Hassanean HA,el-Hamouly MM,el-Moghazy SA,Bishay DW

    更新日期:1993-06-01 00:00:00