Abstract:
:Five flavonostilbenes (alopecurones H, I, J, K and L) and five known ones were isolated from roots of Sophora alopecuroides, in addition to ten other phenolic compounds. A non-enzymatic interconversion of the lavandulyl-substituted flavonostilbenes was observed among alopecurones A, H, I, and K through a Wessely-Moser rearrangement reaction; this was proven by 1D and 2D NMR, HPLC-CD-PDA and HRMS analyses. Bioassay results suggested that flavonostilbenes exhibit significant antibacterial and anti-biofilm formation activities against Staphylococcus epidermidis with MIC values ranging from 3.1 to 12.5μg/mL.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Wan CX,Luo JG,Ren XP,Kong LYdoi
10.1016/j.phytochem.2015.02.022subject
Has Abstractpub_date
2015-08-01 00:00:00pages
290-297eissn
0031-9422issn
1873-3700pii
S0031-9422(15)00088-6journal_volume
116pub_type
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