Kuguacins F-S, cucurbitane triterpenoids from Momordica charantia.

Abstract:

:Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation of fourteen cucurbitane triterpenoids, kuguacins F-S (1-14), including two pentanorcucurbitacins (6 and 7), one octanorcucurbitacin (8), and two trinorcucurbitacins (11 and 12), along with six known analogues. Their structures were elucidated on the basis of extensive spectroscopic and single-crystal X-ray diffraction analyses. Compounds 1-14 exhibited weak anti-HIV-1 activities in vitro.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Chen JC,Liu WQ,Lu L,Qiu MH,Zheng YT,Yang LM,Zhang XM,Zhou L,Li ZR

doi

10.1016/j.phytochem.2008.10.011

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

133-40

issue

1

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(08)00499-8

journal_volume

70

pub_type

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