Abstract:
:Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation of fourteen cucurbitane triterpenoids, kuguacins F-S (1-14), including two pentanorcucurbitacins (6 and 7), one octanorcucurbitacin (8), and two trinorcucurbitacins (11 and 12), along with six known analogues. Their structures were elucidated on the basis of extensive spectroscopic and single-crystal X-ray diffraction analyses. Compounds 1-14 exhibited weak anti-HIV-1 activities in vitro.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Chen JC,Liu WQ,Lu L,Qiu MH,Zheng YT,Yang LM,Zhang XM,Zhou L,Li ZRdoi
10.1016/j.phytochem.2008.10.011subject
Has Abstractpub_date
2009-01-01 00:00:00pages
133-40issue
1eissn
0031-9422issn
1873-3700pii
S0031-9422(08)00499-8journal_volume
70pub_type
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