Abstract：
:The sesquineolignans, saucerneol D and saucerneol E were isolated from the roots of Saururus chinensis together with four known lignans, manassantin A, manassantin B, (-)-saucerneol methyl ether, and (+)-saucernetin. Structure elucidation was based on the analysis of spectroscopic data and anti-inflammatory activity was studied using HeLa cells transfected with NF-kappaB reporter construct. All compounds except for (+)-saucernetin inhibited NF-kappaB dependent reporter gene expression with IC50 values of 2.5-16.9 microM.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Hwang BY,Lee JH,Nam JB,Hong YS,Lee JJdoi
10.1016/s0031-9422(03)00391-1subject
Has Abstractpub_date
2003-10-01 00:00:00pages
765-71issue
3eissn
0031-9422issn
1873-3700pii
S0031942203003911journal_volume
64pub_type
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