Abstract:
OBJECTIVES:The sum of urinary inorganic arsenic (iAs), monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA) concentrations is used for the biological monitoring of occupational iAs exposure. Although DMA is a major metabolite of iAs, it is an inadequate index because high DMA levels are present in urine after seafood consumption. We estimated the urinary iAs+MMA concentration corresponding to iAs exposure. METHODS:We used data from two arsenic speciation analyses of urine samples from 330 Bangladeshi with oral iAs exposure and 172 Japanese workers without occupational iAs exposure using high-performance liquid chromatography with inductively coupled plasma mass spectrometry. RESULTS:iAs, MMA, and DMA, but not arsenobetaine (AsBe), were detected in the urine of the Bangladeshi subjects. The correlation between iAs+MMA+DMA and iAs+MMA was obtained as log (iAs+MMA) = 1.038 log (iAs+MMA+DMA) -0.658. Using the regression formula, the iAs+MMA value was calculated as 2.15 and 7.5 μg As/l, corresponding to 3 and 10 μg As/m(3) of exposures, respectively. In the urine of the Japanese workers, arsenic was mostly excreted as AsBe. We used the 95th percentile of iAs+MMA (12.6 μg As/l) as the background value. The sum of the calculated and background values can be used as a biological indicator of iAs exposure. CONCLUSION:We propose 14.8 and 20.1 μg As/l of urinary iAs+MMA as the biological indicators of 3 and 10 μg As/m(3) iAs exposure, respectively.
journal_name
J Occup Healthjournal_title
Journal of occupational healthauthors
Hata A,Kurosawa H,Endo Y,Yamanaka K,Fujitani N,Endo Gdoi
10.1539/joh.15-0241-OAsubject
Has Abstractpub_date
2016-05-25 00:00:00pages
196-200issue
2eissn
1341-9145issn
1348-9585journal_volume
58pub_type
杂志文章abstract:OBJECTIVES:Occupational lead (Pb) exposure is still an important health problem in the world. Long-term Pb exposure causes several adverse effects. The aim of this study was to investigate the changes of inflammation markers with chronic Pb exposure by analyzing neopterin levels and kynurenine (Kyn) to tryptophan (Trp)...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0273-OA
更新日期:2017-07-27 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章,多中心研究
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更新日期:2006-11-01 00:00:00
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doi:10.1539/joh.13-0244-cs
更新日期:2014-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0111-oa
更新日期:2011-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0100-FS
更新日期:2016-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章,评审
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更新日期:2005-01-01 00:00:00
abstract::Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are synthetic surfactants used in Japan. An epidemiological study of workers exposed to PFOA revealed a significant increase in prostate cancer mortality. A cross-sectional study of PFOA-exposed workers showed that PFOA perturbs sex hormone homeostasis. We...
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更新日期:2004-01-01 00:00:00
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journal_title:Journal of occupational health
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doi:10.1539/joh.15-0253-FS
更新日期:2017-01-24 00:00:00
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pub_type: 杂志文章
doi:10.1002/1348-9585.12146
更新日期:2020-01-01 00:00:00
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更新日期:2014-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0119-oa
更新日期:2014-01-01 00:00:00
abstract::Due to the potential for an influenza pandemic, preparedness for infection control in healthcare settings is essential from the standpoint of occupational health for healthcare workers. We conducted questionnaire surveys among Japanese hospitals to assess preparedness at the individual and institutional levels and the...
journal_title:Journal of occupational health
pub_type: 杂志文章,多中心研究
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更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1539/joh.l9110
更新日期:2010-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2018-0050-OA
更新日期:2018-09-26 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0234-OA
更新日期:2018-07-25 00:00:00
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pub_type: 杂志文章
doi:10.1539/joh.l9080
更新日期:2009-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.10-0072-oa
更新日期:2011-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.o10031
更新日期:2011-01-01 00:00:00
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更新日期:2020-01-01 00:00:00
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更新日期:2016-09-30 00:00:00
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更新日期:2008-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章,评审
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更新日期:2009-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l9006
更新日期:2009-01-01 00:00:00
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更新日期:2004-11-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.10-0053-br
更新日期:2011-01-01 00:00:00
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journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0095-br
更新日期:2013-01-01 00:00:00
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更新日期:2003-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:Among the many chemicals used in a hair salon, exposure to thioglycolic acid (TGA) used for permanent waving solutions (PWS) potentially causes adverse health effects. However, no report has been previously published on the indoor air concentrations of TGA in a beauty salon that contributes to assessment of ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0084-fs
更新日期:2012-01-01 00:00:00