Abstract:
:Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are synthetic surfactants used in Japan. An epidemiological study of workers exposed to PFOA revealed a significant increase in prostate cancer mortality. A cross-sectional study of PFOA-exposed workers showed that PFOA perturbs sex hormone homeostasis. We analyzed their concentrations in surface water samples collected from all over Japan by LC/MS with a solid phase extraction method. The lowest limits of detection (LOD) (ng/L) were 0.06 for PFOA and 0.04 for PFOS. The lowest limits of quantification (LOQ) (ng/L) were 0.1 for both analytes. The levels [geometric mean (GM); geometric standard deviation (GS)] (ng/L) of PFOA and PFOS in the surface waters were GM (GS): 0.97 (3.06) and 1.19 (2.44) for Hokkaido-Tohoku (n=16); 2.84(3.56) and 3.69 (3.93) for Kanto (n=14); 2.50 (2.23) and 1.07 (2.36) for Chubu (n=17); 21.5 (2.28) and 5.73 (3.61) for Kinki (n=8); 1.51 (2.28) and 1.00 (3.42) for Chugoku (n=9); 1.93 (2.40) and 0.89 (3.09) for Kyushu-Shikoku (n=15). The GM of PFOA in Kinki was significantly higher than in other areas (ANOVA p<0.01). Systematic searches of Yodo and Kanzaki Rivers revealed two highly contaminated sites, a public-water-disposal site for PFOA and an airport for PFOS. The former was estimated to release 18 kg of PFOA/d. PFOA in drinking water in Osaka city [40 (1.07) ng/L] was significantly higher than in other areas. The present study confirms that recognizable amounts of PFOA are released in the Osaka area and that people are exposed to PFOA through drinking water ingestion.
journal_name
J Occup Healthjournal_title
Journal of occupational healthauthors
Saito N,Harada K,Inoue K,Sasaki K,Yoshinaga T,Koizumi Adoi
10.1539/joh.46.49subject
Has Abstractpub_date
2004-01-01 00:00:00pages
49-59issue
1eissn
1341-9145issn
1348-9585journal_volume
46pub_type
杂志文章abstract:OBJECTIVES:This report reviews the carcinogenicity of multi-walled carbon nanotubes (MWCNTs) in experimental animals, concentrating on MWNT-7, a straight fibrous MWCNT. METHODS:MWCNTs were administered to mice and rats by intraperitoneal injection, intrascrotal injection, subcutaneous injection, intratracheal instilla...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.17-0102-RA
更新日期:2018-01-25 00:00:00
abstract::This study assessed the relationship of age, poor perception of working condition, poor safety environment, poor management and supervision, risk-taking behavior, emotional instability, negative job involvement, job dissatisfaction, job stress, and poor safety performance of workers to occupational injuries. This case...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.46.470
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:The sum of urinary inorganic arsenic (iAs), monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA) concentrations is used for the biological monitoring of occupational iAs exposure. Although DMA is a major metabolite of iAs, it is an inadequate index because high DMA levels are present in urine after s...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0241-OA
更新日期:2016-05-25 00:00:00
abstract::Using workplaces as a unit for randomization, a randomized controlled trial was conducted to determine the effects of web-based supervisor training on the subject of worksite mental health on job stressors, supervisor support and psychological distress among subordinate workers. A total of eight workplaces of a sales ...
journal_title:Journal of occupational health
pub_type: 杂志文章,随机对照试验
doi:10.1539/joh.48.28
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:Dental caries and periodontal disease are highly prevalent in the Japanese adult population. Oral examination is an effective method to find various oral health problems in their early stages. However, workplace oral examination is not common in Japan. The purpose of this study was to examine the relationshi...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.o10031
更新日期:2011-01-01 00:00:00
abstract::Cadmium fluoride (CdF2, CdF for short) is the most lethal and hepatotoxic of all Cd-containing compounds. The toxic effects of CdF appear to depend on its detoxification and elimination. This study was designed to determine the early dynamics of the absorption, systemic distribution, and metabolism of CdF. The kinetic...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l8016
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the effects of Nickel (Ni) -smelting fumes on oncogenic proteins in vivo and in vitro. METHODS:Ni fallout beside a Ni smelting furnace in a factory was sampled to study its toxic effect. The effects of Ni-smelting fumes on the regulation of PI3K and ERK signaling ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0287-OA
更新日期:2016-09-30 00:00:00
abstract::Due to the potential for an influenza pandemic, preparedness for infection control in healthcare settings is essential from the standpoint of occupational health for healthcare workers. We conducted questionnaire surveys among Japanese hospitals to assess preparedness at the individual and institutional levels and the...
journal_title:Journal of occupational health
pub_type: 杂志文章,多中心研究
doi:10.1539/joh.50.13
更新日期:2008-01-01 00:00:00
abstract::This study was conducted on a thermal exposure chamber designed for assessing workers' thermal hazard. In order to assess the efficacy of the studied chamber, three environmental conditions were selected to simulate high, middle and low thermal impact situations, with air temperatures (Ta) of 43.12, 36.23 and 25.77 ma...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.153
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:Although well-being at work is important for occupational health, multi-dimensional workplace well-being measures do not exist for Japanese workers. The purpose of this study was to investigate the validity of the Japanese version of the Workplace PERMA-Profiler. METHODS:Japanese workers completed online su...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2018-0050-OA
更新日期:2018-09-26 00:00:00
abstract:OBJECTIVES:We investigated the effects of fatigue on NK cell function and lymphocyte subpopulations in nurses performing shift work using a longitudinal design. METHODS:Fifty-seven female nurses engaged in shift work at a hospital in Japan were selected for our study cohort. The hospital used a counterclockwise rotati...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.10-0072-oa
更新日期:2011-01-01 00:00:00
abstract::This paper examines the effects of shift work on the lifestyles of female factory workers. As an indicator of healthy lifestyle habits, we used a scoring system (referred to below as the 'health score') based on Lester Breslow's health habits. The 'health score' of the women was higher than that of the men, but the sh...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.46.192
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:In this study, we focused on the qualitative and quantitative differences of the lung lesions induced by single or multiple intratracheal administration of nickel oxide nanoparticles (NiO). METHODS:Male rats were randomized into groups receiving intratracheal administrations in a single dose or two to four ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0184-OA
更新日期:2017-03-28 00:00:00
abstract:BACKGROUND:Nurses are one of the population groups with the highest prevalence of musculoskeletal disorders (MSDs). At many sites, musculoskeletal symptoms (MS) represent a major health-care burden, adversely affecting nurses' quality of life and giving rise to mental health issues. OBJECTIVES:This study measured the ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12161
更新日期:2020-01-01 00:00:00
abstract::This study presents the results of an investigation of respiratory symptoms, pulmonary function and chest X-ray examinations, and analysis of antibodies to fungi of 197 tussah silk-processing workers and 40 control workers. An industrial hygiene survey and environmental mycological studies were also conducted. The dus...
journal_title:Journal of occupational health
pub_type: 临床试验,杂志文章
doi:10.1539/joh.46.418
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVES:Occupational lead (Pb) exposure is still an important health problem in the world. Long-term Pb exposure causes several adverse effects. The aim of this study was to investigate the changes of inflammation markers with chronic Pb exposure by analyzing neopterin levels and kynurenine (Kyn) to tryptophan (Trp)...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0273-OA
更新日期:2017-07-27 00:00:00
abstract:OBJECTIVES:The aim of this study was to develop and validate a simple and reliable gas chromatography-mass spectrometry (GC-MS) method to simultaneously determine urinary 1-naphthol (1-NAP) and 2-naphthol (2-NAP) for biological monitoring of occupational exposure to naphthalene. METHODS:NAPs were derivatized in situ w...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12144
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Healthcare workers are at high risk of infection from blood-borne pathogens, such as Hepatitis B and C Virus, and Human Immunodeficiency. Occupational exposure to needle-stick injuries (NSIs) continue to have a major health problem in the healthcare systems of developing countries. Thus, this review article ...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1002/1348-9585.12179
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Although many studies have examined locomotive syndrome (LS) among elderly people, few studies have examined LS in young- and middle-aged adults. This study aimed to provide basic data on the epidemiological characteristics of LS, including in young- and middle-aged adults. METHOD:We conducted a cross-secti...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12053
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine ultraviolet (UV) action spectra for cell killing of primary porcine lens epithelial cells (LECs) that can be used to establish guidelines for evaluation of the hazard of cataract due to UV exposure in the workplace. METHODS:Primary porcine LECs were exposed to differen...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0215-oa
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate the effectiveness of supervised exercise among nurses conducting shift work for health promotion. METHODS:A total of 30 healthy female nurses conducting shift work participated in this study and they were randomly assigned to one of the following 2 groups: The supervised exercis...
journal_title:Journal of occupational health
pub_type: 杂志文章,随机对照试验
doi:10.1539/joh.16-0125-OA
更新日期:2017-07-27 00:00:00
abstract::The relationships between alcohol consumption, serum gamma-glutamyltransferase (GGT) levels, and the prevalence of major coronary risk factors were analyzed cross-sectionally in 2,399 male and 1,402 female middle-aged workers, to clarify the effects of moderate alcohol consumption on the development of the metabolic s...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.293
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate whether sedentary job role and gender are reflected by sedentary risk factors within a university campus. METHODS:Following institutional ethical approval, 80 U.K. university campus employees were recruited, and 34 of them (age 47.8 ± 11.9 years, height 169 ± 1.0 cm,...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0158-oa
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:It is common to find doctors working long and odd hours and many at times without rest and sleep. Despite the evidence of adverse risk, jeopardizing patient safety under the hands of fatigue doctors under such working hours has not changed in many places. It has argued that with such training and subsequent ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12121
更新日期:2020-01-01 00:00:00
abstract::In Japan, consultations concerning child abuse cases are increasing rapidly, and the mental health of child-counseling office workers, who must deal with them, has emerged as an issue. To measure the state of mental health of these workers, and to clarify the characteristics of their job-related stress, we sent a ques...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.125
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:Nickel oxide nanoparticles (NiONPs) are representative metal oxide NPs and are categorized as an insoluble nickel compound. Our previous studies suggested that NiONPs have more pulmonary toxicity than micron-sized NiO because they may dissolve slowly and produce many more Ni ions. We confirmed the hypothesis ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12162
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:The aim of this review was to summarize the lessons learned from the experience in protecting the health of workers engaged in operations following the accident at the Fukushima Daiichi Nuclear Power Plant (NPP). METHODS:We reviewed all types of scientific papers examining workers' health found in Medline a...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.15-0084-RA
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:Professional drivers are exposed to diesel engine exhaust and outdoor air pollution while driving. Diesel engine exhaust and outdoor air pollution are known carcinogens causing lung cancer. However, previous epidemiological studies examining lung cancer risk in professional drivers have not shown a consisten...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.14-0222-OA
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:Agricultural use of neonicotinoid (NEO) insecticides has been increasing in recent years, but their biological monitoring methods have been scarcely reported. In this study, we developed and validated a rapid and sensitive method for quantifying urinary NEO concentrations using high-performance liquid chroma...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.14-0077-OA
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Spinal pain is a significant occupational health issue. Whilst neck pain and low back pain have received considerable attention, thoracic spinal pain (TSP) has not. The objective of this study was to systematically identify and report the evidence describing the prevalence and correlates of TSP within occupa...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.k8007
更新日期:2009-01-01 00:00:00