Development of a retrospective job exposure matrix for PCB-exposed workers in capacitor manufacturing.

Abstract:

OBJECTIVES:Polychlorinated biphenyls (PCBs) are considered probable human carcinogens by the International Agency for Research on Cancer and one congener, PCB126, has been rated as a known human carcinogen. A period-specific job exposure matrix (JEM) was developed for former PCB-exposed capacitor manufacturing workers (n=12,605) (1938-1977). METHODS:A detailed exposure assessment for this plant was based on a number of exposure determinants (proximity, degree of contact with PCBs, temperature, ventilation, process control, job mobility). The intensity and frequency of PCB exposures by job for both inhalation and dermal exposures, and additional chemical exposures were reviewed. The JEM was developed in nine steps: (1) all unique jobs (n=1,684) were assessed using (2) defined PCB exposure determinants; (3) the exposure determinants were used to develop exposure profiles; (4) similar exposure profiles were combined into categories having similar PCB exposures; (5) qualitative intensity (high-medium-low-baseline) and frequency (continuous-intermittent) ratings were developed, and (6) used to qualitatively rate inhalation and dermal exposure separately for each category; (7) quantitative intensity ratings based on available air concentrations were developed for inhalation and dermal exposures based on equal importance of both routes of exposure; (8) adjustments were made for overall exposure, and (9) for each category the product of intensity and frequency was calculated, and exposure in the earlier era was weighted. RESULTS:A period-specific JEM modified for two eras of stable PCB exposure conditions. CONCLUSIONS:These exposure estimates, derived from a systematic and rigorous use of the exposure determinant data, lead to cumulative PCB exposure-response relationships in the epidemiological cancer mortality and incidence studies of this cohort.

journal_name

J Occup Health

authors

Hopf NB,Waters MA,Ruder AM,Prince MM

doi

10.1539/joh.l9151

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

199-208

issue

4

eissn

1341-9145

issn

1348-9585

pii

JST.JSTAGE/joh/L9151

journal_volume

52

pub_type

杂志文章
  • Measurement of concentrations of thioglycolic acid, dithiodiglycolic acid and ammonia in indoor air of a beauty salon.

    abstract:OBJECTIVES:Among the many chemicals used in a hair salon, exposure to thioglycolic acid (TGA) used for permanent waving solutions (PWS) potentially causes adverse health effects. However, no report has been previously published on the indoor air concentrations of TGA in a beauty salon that contributes to assessment of ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.12-0084-fs

    authors: Oikawa D,Takeuchi W,Murata S,Takahashi K,Sekine Y

    更新日期:2012-01-01 00:00:00

  • Exposure assessment of ETBE in gas station workers and gasoline tanker truck drivers.

    abstract:OBJECTIVES:In order to measure occupational exposure concentrations of ethyl tertiary-butyl ether (ETBE), we developed a diffusive sampling method for monitoring ETBE and performed an ETBE exposure assessment. METHODS:The applicability of diffusive samplers was examined by exposing the samplers to ETBE vapor in test c...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.11-0111-oa

    authors: Eitaki Y,Kawai T,Omae K

    更新日期:2011-01-01 00:00:00

  • Smoking rate trends in Korean occupational groups: analysis of KNHANES 1998-2009 data.

    abstract:OBJECTIVES:This study aimed to investigate changes in the smoking rate among Korean adults from 1998-2009 by gender and occupational groups. METHODS:Using the data from the first (1998), second (2001), third (2005) and fourth (2009) waves of the Korean National Health and Nutrition Examination Survey (KNHANES), we exa...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.12-0148-oa

    authors: Jang TW,Kim HR,Choi SE,Yim HW,Lee HE,Myong JP,Koo JW

    更新日期:2012-01-01 00:00:00

  • Exploratory study of brain waves and corresponding brain regions of fatigue on-call doctors using quantitative electroencephalogram.

    abstract:OBJECTIVES:It is common to find doctors working long and odd hours and many at times without rest and sleep. Despite the evidence of adverse risk, jeopardizing patient safety under the hands of fatigue doctors under such working hours has not changed in many places. It has argued that with such training and subsequent ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1002/1348-9585.12121

    authors: Xavier G,Su Ting A,Fauzan N

    更新日期:2020-01-01 00:00:00

  • Incidence and characteristics of needlestick injuries among medical trainees at a community teaching hospital: A cross-sectional study.

    abstract:OBJECTIVES:This field study aimed to determine the incidence and distribution of needlestick injuries among medical trainees at a community teaching hospital in Toronto, Canada. METHODS:The study was performed during the 2013-2015 academic years at Toronto East General Hospital (TEGH), a University of Toronto-affiliat...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.15-0253-FS

    authors: Ouyang B,Li LD,Mount J,Jamal AJ,Berry L,Simone C,Law M,Tai RM

    更新日期:2017-01-24 00:00:00

  • The influence of the thermal modification of pine (Pinus sylvestris L.) wood on the creation of fine dust particles in plane milling: Fine dust creation in the plane milling of thermally modified pine wood.

    abstract:OBJECTIVES:The aim of the study was to determine the effect of parameters of the thermal modification process and machining on the size distribution of dust particles of Scots pine (Pinus sylvestris L.) generated during lengthwise milling. METHOD:Unmodified wood and thermally modified wood at temperatures of 130, 160,...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1002/1348-9585.12075

    authors: Piernik M,Rogoziński T,Krauss A,Pinkowski G

    更新日期:2019-11-01 00:00:00

  • The usefulness of sleep apnea syndrome screening using a portable pulse oximeter in the workplace.

    abstract::Sleep Apnea Syndrome (SAS) is a condition characterized by sleep-disordered breathing resulting in health impairment and sleep problems. From the viewpoints of the prevention of health impairment, accidents at work and traffic accidents, active implementation of screening for SAS in workplaces is necessary. Using a po...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.49.1

    authors: Niijima K,Enta K,Hori H,Sashihara S,Mizoue T,Morimoto Y

    更新日期:2007-01-01 00:00:00

  • Prevalence of occupational exposure to needle-stick injury and associated factors among healthcare workers of developing countries: Systematic review.

    abstract:BACKGROUND:Healthcare workers are at high risk of infection from blood-borne pathogens, such as Hepatitis B and C Virus, and Human Immunodeficiency. Occupational exposure to needle-stick injuries (NSIs) continue to have a major health problem in the healthcare systems of developing countries. Thus, this review article ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审

    doi:10.1002/1348-9585.12179

    authors: Mengistu DA,Tolera ST

    更新日期:2020-01-01 00:00:00

  • Abnormalities in cadmium fluoride kinetics in serum, bile, and urine after single intravenous administration of toxic doses to rats.

    abstract::Cadmium fluoride (CdF2, CdF for short) is the most lethal and hepatotoxic of all Cd-containing compounds. The toxic effects of CdF appear to depend on its detoxification and elimination. This study was designed to determine the early dynamics of the absorption, systemic distribution, and metabolism of CdF. The kinetic...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.l8016

    authors: Dote T,Adachi K,Yamadori E,Imanishi M,Tsuji H,Tanida E,Kono K

    更新日期:2008-01-01 00:00:00

  • Sedentary risk factors across genders and job roles within a university campus workplace: preliminary study.

    abstract:OBJECTIVES:The aim of this study was to investigate whether sedentary job role and gender are reflected by sedentary risk factors within a university campus. METHODS:Following institutional ethical approval, 80 U.K. university campus employees were recruited, and 34 of them (age 47.8 ± 11.9 years, height 169 ± 1.0 cm,...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.12-0158-oa

    authors: Alkhatib A

    更新日期:2013-01-01 00:00:00

  • Determining of crystalline silica in respirable dust samples by infrared spectrophotometry in the presence of interferences.

    abstract::Infrared Spectrophotometry (IR) is now widely used to determine crystalline silica in industrial dust samples. Though the IR method has many advantages when dealing with respirable dust samples, some serious analytical errors are often caused by interference minerals contamination. These minerals have a characteristic...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.45.94

    authors: Ojima J

    更新日期:2003-03-01 00:00:00

  • Acute arsine poisoning confirmed by speciation analysis of arsenic compounds in the plasma and urine by HPLC-ICP-MS.

    abstract:OBJECTIVES:Arsine, a potent hemolytic agent, is widely used in the semiconductor industry. We report a case of arsine poisoning confirmed by arsenic speciation analysis in serum and urine that occurred in a recycling factory. CASE:A male worker in his twenties noticed hematuria 3 h after finishing work and was admitte...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.l10108

    authors: Yoshimura Y,Endo Y,Shimoda Y,Yamanaka K,Endo G

    更新日期:2011-01-01 00:00:00

  • Pulmonary toxicity in mice by 2- and 13-week inhalation exposures to indium-tin oxide and indium oxide aerosols.

    abstract:OBJECTIVES:Inhalation toxicities of indium-tin oxide (ITO) and indium oxide (IO) in mice were characterized in comparison with those previously reported in rats. METHODS:B6C3F(1) mice of both sexes were exposed by inhalation to ITO or IO aerosol for 6 h/day, 5 day/wk for 2 wk at 0, 0.1, 1, 10 or 100 mg/m(3) or 13 wk a...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.10-0053-br

    authors: Nagano K,Nishizawa T,Eitaki Y,Ohnishi M,Noguchi T,Arito H,Fukushima S

    更新日期:2011-01-01 00:00:00

  • Distribution and identification of airborne fungi in railway stations in Tokyo, Japan.

    abstract:OBJECTIVES:The current study was performed to (1) understand the distribution of airborne fungi culturable on dichloran-glycerol agar (DG18) media over a one-year monitoring period, (2) identify the types of airborne fungi collected, and (3) compare and contrast under- and above-ground spaces, in two railway stations i...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.o9022

    authors: Kawasaki T,Kyotani T,Ushiogi T,Izumi Y,Lee H,Hayakawa T

    更新日期:2010-01-01 00:00:00

  • A long-term perspective on cardiovascular job stress research.

    abstract::This review provides perspectives on cardiovascular occupational stress research since the 1960s until now. The author argues for closer links between basic science and clinical follow-up examinations of patients. In an excellent way urinary excretion of adrenaline and noradrenaline during wake hours mirrors day to da...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审

    doi:10.1002/1348-9585.12032

    authors: Theorell T

    更新日期:2019-01-01 00:00:00

  • The Japanese Workplace PERMA-Profiler: A validation study among Japanese workers.

    abstract:OBJECTIVES:Although well-being at work is important for occupational health, multi-dimensional workplace well-being measures do not exist for Japanese workers. The purpose of this study was to investigate the validity of the Japanese version of the Workplace PERMA-Profiler. METHODS:Japanese workers completed online su...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.2018-0050-OA

    authors: Watanabe K,Kawakami N,Shiotani T,Adachi H,Matsumoto K,Imamura K,Matsumoto K,Yamagami F,Fusejima A,Muraoka T,Kagami T,Shimazu A,L Kern M

    更新日期:2018-09-26 00:00:00

  • Lung cancer risk in professional drivers in Korea: A population-based proportionate cancer incidence ratio study.

    abstract:OBJECTIVES:Professional drivers are exposed to diesel engine exhaust and outdoor air pollution while driving. Diesel engine exhaust and outdoor air pollution are known carcinogens causing lung cancer. However, previous epidemiological studies examining lung cancer risk in professional drivers have not shown a consisten...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.14-0222-OA

    authors: Koh DH,Kong HJ,Oh CM,Jung KW,Park D,Won YJ

    更新日期:2015-01-01 00:00:00

  • Association between dental consultation and oral health status among male Japanese employees.

    abstract:OBJECTIVE:To investigate the association between dental consultation and oral health status among male Japanese employees. METHODS:The participants were 3351 male employees who received a workplace oral health examination conducted at the ages of 35, 40, 45, 50, 55, and 59 years before retirement in conjunction with a...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1002/1348-9585.12104

    authors: Shimazaki Y,Nonoyama T,Miyano Y,Miyata Y,Hisada K,Nagasawa T

    更新日期:2020-01-01 00:00:00

  • Changes in health habits of female shift workers.

    abstract::This paper examines the effects of shift work on the lifestyles of female factory workers. As an indicator of healthy lifestyle habits, we used a scoring system (referred to below as the 'health score') based on Lester Breslow's health habits. The 'health score' of the women was higher than that of the men, but the sh...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.46.192

    authors: Kaneko SY,Maeda T,Sasaki A,Sato A,Tanaka K,Kobayashi T,Tanaka M,Fukushima T

    更新日期:2004-05-01 00:00:00

  • Personality and resilience associated with perceived fatigue of local government employees responding to disasters.

    abstract:OBJECTIVES:According to some newspapers, concerns are growing over the health of local government employees in the Great East Japan Earthquake disaster areas. Concerns were consistently present after the Hanshin-Awaji and Niigata-Chuetsu earthquakes but not studied analytically. METHODS:Municipal employees responding ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.12-0095-br

    authors: Kitamura H,Shindo M,Tachibana A,Honma H,Someya T

    更新日期:2013-01-01 00:00:00

  • Effects of co-exposure to noise and mixture of organic solvents on blood pressure.

    abstract:OBJECTIVES:Independent exposure to noise or organic solvents is reported to be associated with cardiovascular effects, but the effect of joint exposure is unclear. The present study aimed to investigate effects of noise, a mixture of organic solvents (N,N-dimethylformamide (DMF) and toluene) and their interaction on hy...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.l8121

    authors: Chang TY,Wang VS,Hwang BF,Yen HY,Lai JS,Liu CS,Lin SY

    更新日期:2009-01-01 00:00:00

  • Biological monitoring of exposure: trends and key developments.

    abstract::The concept of biological monitoring (BM) has gained the special interest of individual scientists and international organizations. Today, when analytical problems have almost ceased due to new laboratory techniques and quality assurance systems, the methods for interpretation of results have become the most important...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审

    doi:10.1539/joh.47.22

    authors: Jakubowski M,Trzcinka-Ochocka M

    更新日期:2005-01-01 00:00:00

  • Simple and reliable method to simultaneously determine urinary 1- and 2-naphthol using in situ derivatization and gas chromatography-mass spectrometry for biological monitoring of naphthalene exposure in occupational health practice.

    abstract:OBJECTIVES:The aim of this study was to develop and validate a simple and reliable gas chromatography-mass spectrometry (GC-MS) method to simultaneously determine urinary 1-naphthol (1-NAP) and 2-naphthol (2-NAP) for biological monitoring of occupational exposure to naphthalene. METHODS:NAPs were derivatized in situ w...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1002/1348-9585.12144

    authors: Takeuchi A,Nakamura S,Namera A,Kondo T,Onuki H,Yamamoto S,Okamura S,Nishinoiri O,Endo Y,Miyauchi H,Endo G

    更新日期:2020-01-01 00:00:00

  • Relationship between receiving a workplace oral health examination including oral health instruction and oral health status in the Japanese adult population.

    abstract:OBJECTIVES:Dental caries and periodontal disease are highly prevalent in the Japanese adult population. Oral examination is an effective method to find various oral health problems in their early stages. However, workplace oral examination is not common in Japan. The purpose of this study was to examine the relationshi...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.o10031

    authors: Oshikohji T,Shimazaki Y,Shinagawa T,Fukui N,Akifusa S,Hirata Y,Yamashita Y

    更新日期:2011-01-01 00:00:00

  • Competencies required for occupational health nurses.

    abstract:OBJECTIVES:For occupational health (OH) nurses to perform activities effectively, not only skills and knowledge but also competencies proposed by Dr. McClelland are indispensable. This study aimed to identify competencies required for OH nurses and to show their structure diagram. METHODS:Qualitative descriptive resea...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.16-0188-OA

    authors: Kono K,Goto Y,Hatanaka J,Yoshikawa E

    更新日期:2017-11-25 00:00:00

  • Review of health issues of workers engaged in operations related to the accident at the Fukushima Daiichi Nuclear Power Plant.

    abstract:OBJECTIVES:The aim of this review was to summarize the lessons learned from the experience in protecting the health of workers engaged in operations following the accident at the Fukushima Daiichi Nuclear Power Plant (NPP). METHODS:We reviewed all types of scientific papers examining workers' health found in Medline a...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审

    doi:10.1539/joh.15-0084-RA

    authors: Hiraoka K,Tateishi S,Mori K

    更新日期:2015-01-01 00:00:00

  • Environmental mycological study and respiratory disease investigation in tussah silk processing workers.

    abstract::This study presents the results of an investigation of respiratory symptoms, pulmonary function and chest X-ray examinations, and analysis of antibodies to fungi of 197 tussah silk-processing workers and 40 control workers. An industrial hygiene survey and environmental mycological studies were also conducted. The dus...

    journal_title:Journal of occupational health

    pub_type: 临床试验,杂志文章

    doi:10.1539/joh.46.418

    authors: Chen J,Shi J,Wang S,Yang S,Lou J,Liu Z

    更新日期:2004-09-01 00:00:00

  • Development of a work improvement checklist for occupational mental health focused on requests from workers.

    abstract:OBJECTIVES:To develop tools offering definite orientation for managers and employees to support their work improvement through occupational mental health. This research was a part of the Mental Health Improvement & Reinforcement Study (MIR study), conducted from October 2004 to March 2006. METHODS:We developed a trial...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.l8081

    authors: Tahara H,Yamada T,Nagafuchi K,Shirakawa C,Suzuki K,Mafune K,Kubota S,Hiro H,Mishima N,Nagata S

    更新日期:2009-01-01 00:00:00

  • The value of high resolution computed tomography in the diagnostics of small opacities and complications of silicosis in mine machinery manufacturing workers, compared to radiography.

    abstract::The purpose of this study was to assess the value and usefulness of high resolution computed tomography (HRCT) in the diagnostics of small opacities and complications of silicosis in mine machinery manufacturing workers, compared to conventional radiograms. The diagnosis of silicosis is mainly based on the radiologica...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,随机对照试验

    doi:10.1539/joh.l8015

    authors: Sun J,Weng D,Jin C,Yan B,Xu G,Jin B,Xia S,Chen J

    更新日期:2008-01-01 00:00:00

  • The associations between menstrual function and life style/working conditions among nurses in Taiwan.

    abstract::This study was aimed at understanding the relationship among menstrual pattern, dysmenorrhea, life style and working conditions in nurses. The nurses were randomly selected from a medical center in Northern Taiwan. Each subject completed daily records including life and working conditions during the study period. The ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章

    doi:10.1539/joh.47.149

    authors: Chung FF,Yao CC,Wan GH

    更新日期:2005-03-01 00:00:00