Abstract:
OBJECTIVES:Allyl nitrile (3-butenenitrile) occurs naturally in the environment, in particular, in cruciferous vegetables, indicating a possible daily intake of the compound. There is no report on actual health effects of allyl nitrile in humans, although it is possible that individuals in the environment are at a risk of exposure to allyl nitrile. However, little is known about its quantitative assessment for the environment and bioactivity in the body. This study provides a review of previous accumulated studies on allyl nitrile. METHODS:Published literature on allyl nitrile was examined for findings on toxicity, metabolism, risk of various cancers, generation, intake estimates, and low-dose effects in the body. RESULTS:High doses of allyl nitrile produce toxicity characterized by behavioral abnormalities, which are considered to be produced by an active metabolite, 3,4-epoxybutyronitrile. Cruciferous vegetables have been shown to have a potential role in reducing various cancers. Hydrolysis of the glucosinolate sinigrin, rich in cruciferous vegetables, results in the generation of allyl nitrile. An intake of allyl nitrile is estimated at 0.12 μmol/kg body weight in Japan. Repeated exposure to low doses of allyl nitrile upregulates antioxidant/phase II enzymes in various tissues; this may contribute to a reduction in neurotoxicity and skin inflammation. These high and low doses are far more than the intake estimate. CONCLUSION:Allyl nitrile in the environment is a compound with diverse bioactivities in the body, characterized by inducing behavioral abnormalities at high doses and some antioxidant/phase II enzymes at low doses.
journal_name
J Occup Healthjournal_title
Journal of occupational healthauthors
Tanii Hdoi
10.1539/joh.16-0147-RAsubject
Has Abstractpub_date
2017-03-28 00:00:00pages
104-111issue
2eissn
1341-9145issn
1348-9585journal_volume
59pub_type
杂志文章,评审abstract:OBJECTIVE:Occupational diseases (OD) are among the most significant issues of work life, with economic, medical, social, and ethical aspects. The majority of studies concerning OD focus on the causes or medical outcomes of OD. There are a limited number of studies investigating the social and economic impacts of being ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0282-OA
更新日期:2018-11-27 00:00:00
abstract:OBJECTIVES:To develop tools offering definite orientation for managers and employees to support their work improvement through occupational mental health. This research was a part of the Mental Health Improvement & Reinforcement Study (MIR study), conducted from October 2004 to March 2006. METHODS:We developed a trial...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l8081
更新日期:2009-01-01 00:00:00
abstract::Using workplaces as a unit for randomization, a randomized controlled trial was conducted to determine the effects of web-based supervisor training on the subject of worksite mental health on job stressors, supervisor support and psychological distress among subordinate workers. A total of eight workplaces of a sales ...
journal_title:Journal of occupational health
pub_type: 杂志文章,随机对照试验
doi:10.1539/joh.48.28
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:Professional drivers are exposed to diesel engine exhaust and outdoor air pollution while driving. Diesel engine exhaust and outdoor air pollution are known carcinogens causing lung cancer. However, previous epidemiological studies examining lung cancer risk in professional drivers have not shown a consisten...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.14-0222-OA
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate two-point discrimination (2PD) sense and kinesthetic sense dysfunctions in carpal tunnel syndrome (CTS) patients compared with a healthy group. METHODS:The 2PD sense, muscle force, and kinesthetic differentiation (KD) of strength; the range of motion in radiocarpal arti...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0108-OA
更新日期:2016-06-16 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the association between skill underutilization, a psychological job stressor proposed in the NIOSH (National Institute for Occupational Safety and Health) job stress model, and the prevalence of hypertension. METHODS:We studied sitting blood pressure and fasting bloo...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0146-br
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To present the pitiable working conditions of clinical waste pickers in hospitals in the Northwest region of Cameroon and associated exposure to health hazards. METHODS:Observe clinical waste pickers as they carry out their functions for three days and carry out informal consultations (discussion) with the w...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.q9004
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:The purpose of the present study was to obtain knowledge for improvement of the housing and life among radiation decontamination workers by examining the effect of housing type on anxiety over lack of privacy. METHODS:This cross-sectional study comprised 544 male radiation decontamination workers in Fukushi...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2018-0007-OA
更新日期:2018-09-26 00:00:00
abstract:OBJECTIVES:Among the many chemicals used in a hair salon, exposure to thioglycolic acid (TGA) used for permanent waving solutions (PWS) potentially causes adverse health effects. However, no report has been previously published on the indoor air concentrations of TGA in a beauty salon that contributes to assessment of ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0084-fs
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to determine the effect of parameters of the thermal modification process and machining on the size distribution of dust particles of Scots pine (Pinus sylvestris L.) generated during lengthwise milling. METHOD:Unmodified wood and thermally modified wood at temperatures of 130, 160,...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12075
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:Titanium dioxide nanoparticles are widely used as UV filters in cosmetics and as a photocatalyst. We evaluated pulmonary responses to different crystal forms of TiO2 nanoparticles. METHODS:We used 4 different TiO2 samples with similar specific surface areas (anatase, rutile, amorphous, and P25). Each sample ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0094-OA
更新日期:2016-11-29 00:00:00
abstract:OBJECTIVES:The aim of this review was to summarize the lessons learned from the experience in protecting the health of workers engaged in operations following the accident at the Fukushima Daiichi Nuclear Power Plant (NPP). METHODS:We reviewed all types of scientific papers examining workers' health found in Medline a...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.15-0084-RA
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to develop and validate a simple and reliable gas chromatography-mass spectrometry (GC-MS) method to simultaneously determine urinary 1-naphthol (1-NAP) and 2-naphthol (2-NAP) for biological monitoring of occupational exposure to naphthalene. METHODS:NAPs were derivatized in situ w...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12144
更新日期:2020-01-01 00:00:00
abstract::The concept of biological monitoring (BM) has gained the special interest of individual scientists and international organizations. Today, when analytical problems have almost ceased due to new laboratory techniques and quality assurance systems, the methods for interpretation of results have become the most important...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.47.22
更新日期:2005-01-01 00:00:00
abstract::Slovenia is a small, fast developing country in the EU with approximately 2,000,000 inhabitants and 700,000 employed. Occupational medicine has been present in Slovenia for as long as 500 yr. Today, 130 specialists of occupational medicine are in charge of health protection of the employed (including transport workers...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.47.193
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:Work-related psychosocial hazards are associated with adverse health outcomes among workers. The association between psychosocial hazards and physiological health outcomes among laboratory technicians has not been studied previously. The objective of this study was to measure the association between work-rel...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0050-fs
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The current study was performed to (1) understand the distribution of airborne fungi culturable on dichloran-glycerol agar (DG18) media over a one-year monitoring period, (2) identify the types of airborne fungi collected, and (3) compare and contrast under- and above-ground spaces, in two railway stations i...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.o9022
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:There is concern that sound via earphones and headphones attached to headsets used in workplaces may be a risk factor for noise-induced hearing loss (NIHL). Although there are some previous studies investigating exposure to noise from headphones, almost none have assessed the risks to workers who use earphon...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0285-oa
更新日期:2014-01-01 00:00:00
abstract::This review provides perspectives on cardiovascular occupational stress research since the 1960s until now. The author argues for closer links between basic science and clinical follow-up examinations of patients. In an excellent way urinary excretion of adrenaline and noradrenaline during wake hours mirrors day to da...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1002/1348-9585.12032
更新日期:2019-01-01 00:00:00
abstract::This study prospectively examined the association between perceived noise exposure at work and cerebrovascular diseases among Japanese male workers. A baseline survey was conducted between 1988 and 1990, which involved 110,792 inhabitants (age range: 40-79 yr) from 45 areas throughout Japan. Subsequent causes of death...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.382
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to examine sexual harassment (SH) among hospital staffs in Taiwan, in terms of three-month incidence rate, the frequency of each type and the perception of SH, perpetrated by coworkers, patients and patients' families and to investigate the gender differences for these issues. ME...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0063-fs
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:It is common to find doctors working long and odd hours and many at times without rest and sleep. Despite the evidence of adverse risk, jeopardizing patient safety under the hands of fatigue doctors under such working hours has not changed in many places. It has argued that with such training and subsequent ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12121
更新日期:2020-01-01 00:00:00
abstract::In Japan, consultations concerning child abuse cases are increasing rapidly, and the mental health of child-counseling office workers, who must deal with them, has emerged as an issue. To measure the state of mental health of these workers, and to clarify the characteristics of their job-related stress, we sent a ques...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.125
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:Long working hours may impact human health. In Japan, teachers tend to work long hours. From 2002 to 2012, the number of leaves of absence due to diseases other than mental disorders, or mental disorders among public school teachers increased by 1.3 times (from 2,616 to 3,381), or 1.8 times (from 2,687 to 4,...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0053-OA
更新日期:2015-01-01 00:00:00
abstract::Many dental health workers suffer from musculoskeletal disorders in the upper extremities. In addition to ergonomic factors, psychosocial work characteristics have been linked to musculoskeletal disorders. The present cross-sectional study aimed at investigating how musculoskeletal disorders in the upper extremities (...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.48.192
更新日期:2006-05-01 00:00:00
abstract::Infrared Spectrophotometry (IR) is now widely used to determine crystalline silica in industrial dust samples. Though the IR method has many advantages when dealing with respirable dust samples, some serious analytical errors are often caused by interference minerals contamination. These minerals have a characteristic...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.94
更新日期:2003-03-01 00:00:00
abstract::This paper investigates the effects of tanshin funin, a posting without family, on the health of married male workers. A prospective study using the pair-matched method was performed. One hundred and twenty-nine married male tanshin funin workers in their 40s and 50s and as many matched workers living with their famil...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.48.113
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:The present study examined how job demands affect an intimate partner's well-being. We hypothesized that job demands have a negative influence on partner well-being through the experience of work-family conflict (WFC) and an impaired quality of the relationship (reduced social support and increased social un...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l8160
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Numerous workers have participated in recovery efforts following the accident that occurred at the Tokyo Electric Power Company (TEPCO) Fukushima Daiichi Nuclear Power Plant after the Great East Japan Earthquake. These workers, belonging to various companies, have been engaged in various tasks since the acci...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.17-0150-CS
更新日期:2018-03-27 00:00:00
abstract:OBJECTIVES:Occupational lead (Pb) exposure is still an important health problem in the world. Long-term Pb exposure causes several adverse effects. The aim of this study was to investigate the changes of inflammation markers with chronic Pb exposure by analyzing neopterin levels and kynurenine (Kyn) to tryptophan (Trp)...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0273-OA
更新日期:2017-07-27 00:00:00