Abstract:
:The "holobiont" concept, defined as the collective contribution of the eukaryotic and prokaryotic counterparts to the multicellular organism, introduces a complex definition of individuality enabling a new comprehensive view of human evolution and personalized characteristics. Here, we provide snapshots of the evolving microbial-host associations and relations during distinct milestones across the lifespan of a human being. We discuss the current knowledge of biological symbiosis between the microbiome and its host and portray the challenges in understanding these interactions and their potential effects on human physiology, including microbiome-nervous system inter-relationship and its relevance to human variation and individuality.
journal_name
Celljournal_title
Cellauthors
Kundu P,Blacher E,Elinav E,Pettersson Sdoi
10.1016/j.cell.2017.11.024subject
Has Abstractpub_date
2017-12-14 00:00:00pages
1481-1493issue
7eissn
0092-8674issn
1097-4172pii
S0092-8674(17)31371-5journal_volume
171pub_type
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