Abstract：
:Changes in plasma insulin and glucose concentrations before and after feeding were measured in six female subjects (post-obese) who had regained a normal body mass after a history of severe obesity (mean weight loss, 37.1 +/- 2.6 kg). The responses of the post-obese group were compared with a group of weight- and age-matched subjects who had not been obese (lean). After an overnight fast subjects were fed a meal at 09.00 h and 13.10 h. Fasting and post-prandial insulin concentrations were lower in post-obese than in lean subjects. Immediately after beginning to eat at 13.10 h all subjects showed a rise in insulin concentration with no change in glucose concentration. In this pre-absorptive period there was no significant difference in insulin concentration between post-obese and lean subjects, although the increment in insulin concentration over baseline values was greater in post-obese subjects (P less than 0.05). It is concluded that abnormalities of insulin secretion and action remain after weight loss by obese subjects. These abnormalities may predispose to hyperphagia and accumulation of excess adiposity.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Fletcher JM,McNurlan MA,McHardy KCsubject
Has Abstractpub_date
1989-08-01 00:00:00pages
539-45issue
8eissn
0954-3007issn
1476-5640journal_volume
43pub_type
杂志文章abstract：BACKGROUND/OBJECTIVES:Exclusive enteral nutrition (EEN) is a safe and effective treatment modality for inducing remission in paediatric Crohn's disease (CD). The primary aim of this study was to compare the outcomes of EEN to corticosteroid (CS) therapy in newly diagnosed, treatment-naïve patients with CD. A secondary ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.210
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:To estimate the intake of ruminant trans fatty acids (TFA) in the Danish population aged 1-80 years. DESIGN:Descriptive study. SUBJECTS:A sex- and age-stratified random sample drawn from the Danish Civil Registration System. A total of 3098 participants (51% female) aged 1-80 years were included. The partic...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602316
更新日期：2006-03-01 00:00:00
abstract：OBJECTIVES:To determine the content of glutamine in major food proteins. SUBJECTS/METHODS:We used a validated 131-food item food frequency questionnaire (FFQ) to identify the foods that contributed the most to protein intake among 70,356 women in the Nurses' Health Study (NHS, 1984). The content of glutamine and other...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.110
更新日期：2009-12-01 00:00:00
abstract：:The pharmacokinetics of vitamin C following a 500 mg oral tablet dose were compared in a group of fourteen healthy young women whose age was 26.0 +/- 2.8 years (mean +/- s.d.), and in a group of fourteen healthy elderly women aged 68.1 +/- 2.6 years. The body composition of each subject was assessed using several anth...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Alcohol-induced hypoglycaemia is a well-known phenomenon in insulin-treated diabetic subjects. Less attention has been paid to the impact of alcohol on blood glucose and insulin responses in non-insulin dependent diabetic subjects. The aim of this study was to investigate the acute metabolic effects of different alcoh...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1993-09-01 00:00:00
abstract：:Nutrient intake was assessed for 15 long-stay elderly patients by 7-d weighed inventory. Analysis revealed neither significant day-to-day nor weekday/weekend variations for any studied nutrient except fibre. It would appear that acceptable indications of customary intake in this population can be achieved by measureme...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
abstract：:The article deals with the generation of a prediction equation for basal metabolic rate (BMR) of well-nourished Indian males, from prospective measurements on 121 males, using a single validated technique. The equation related BMR to simple measures such as weight (WT) and age, and was given by: BMR (kJ/d) = 48.7 * WT...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is a high prevalence of diabetes mellitus associated with insulin resistance in Indian adults, probably due to an inappropriately high accumulation of body fat at lower body mass indices (BMIs, kg/m(2)), as well as to a lower skeletal muscle mass. Although skeletal muscle is an important sit...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.32
更新日期：2009-10-01 00:00:00
abstract：:The application of molecular biology and genetics in the field of cholesterol and lipoprotein metabolism has resulted in a tremendous expansion of knowledge during the past decade. In this short review, the normal metabolism of lipoproteins is first discussed briefly, and several clinically important examples of genet...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1992-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Present study aims to longitudinally explore independent association of physical activity and sedentary behaviors with body weight. SUBJECTS/METHODS:This study included 15050 adults who have complete demographic and dietary data, leisure time physical activity (LTPA) and sedentary behavior evalua...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.262
更新日期：2017-03-01 00:00:00
abstract：:The relationship between diet and attained height was studied in children and adolescents in Southern California. Diet pattern was determined from an extensive food frequency questionnaire in 1765 Caucasian children of 7-18 years, attending state schools (452 m and 443 f) and Seventh-day Adventist schools (427 m and 4...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Undernutrition status at hospital admission is related to increased hospital costs. Handgrip strength (HGS) is an indicator of undernutrition, but the ability of HGS to predict hospitalization costs has yet to be studied. OBJECTIVE:To explore whether HGS measurement at hospital admission can predict patient...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.242
更新日期：2015-02-01 00:00:00
abstract：:It has been suggested that energy requirements are either proportional to the BMR (FAO/WHO/UNU, 1985) or to body weight (WHO, 1973). The present analysis sought to distinguish between these two possibilities by determining whether, in rural Gambian women, energy expenditure was more nearly proportional to the BMR or t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1988-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the ability of designer eggs enriched in vitamin E, lutein, selenium (Se) and docosahexaenoic acid (DHA) to deliver micronutrients to the human in a palatable and visually acceptable form. DESIGN:Double-blind, placebo-controlled trial, two treatment groups balanced for sex and age. SETTING:Depar...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1600939
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Colonic fermentation of dietary fiber may improve insulin sensitivity by the metabolic effects of short chain fatty acids (SCFA) in reducing free fatty acids (FFA). The main objectives of this study were to compare peripheral uptake of acetate (AC) in participants with normal (<40 pmol/l, NI) and ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2012.98
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVE:To describe the availability of food items at primary and secondary schools in Belgium-Flanders and to examine the influence of school food policy (availability of food items, school food rules, nutrition education programmes) and aggregated school socioeconomical status (AGG SES) on the consumption of fruit,...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602068
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:This study evaluates the feasibility among preschoolers of the 2 × 24-h dietary recalls (24-HDRs) method combined with a food-recording booklet (FRB), using EPIC-Soft pc-program for the 24-HDR (the software developed to conduct 24-HDRs in the European Prospective Investigation into Cancer and Nutr...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2011.91
更新日期：2011-07-01 00:00:00
abstract：:The association of calcium intake with risk of developing hypertension in the general population has not been established yet. We systematically searched PubMed and Scopus databases up to February 2018 to find prospective observational studies investigating the association of calcium intake with risk of developing hyp...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,meta分析
doi：10.1038/s41430-018-0275-y
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVES:To determine the resting metabolic rate in a sample of the Italian population, and to evaluate the validity of predictive equations for resting metabolic rate (RMR) from the literature in normal and obese subjects. DESIGN:Cross-sectional observational study. SETTINGS:Department of Human Physiology and Nutr...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601149
更新日期：2001-03-01 00:00:00
abstract：:This study examined the association of dietary calcium intake with incident type 2 diabetes by a meta-analysis and explored the potential confounding by magnesium. Potential studies were identified by searching the PubMed database in September 2011. Prospective cohort studies that reported relative risks (RR) with 95%...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,meta分析
doi：10.1038/ejcn.2012.5
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVE:To evaluate dietary habits and nutritional status of Spanish school children and adolescents, and their relationship with the Mediterranean Diet. DESIGN:Cross-sectional study by face-to-face interview. SETTING:Free living children and adolescents of all Spanish regions. SUBJECTS:A random sample of 3166 peo...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601812
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To monitor the dietary intake of energy, macro- and micronutrients in asylum seeker children. DESIGN AND SETTING:Cross-sectional study in three asylum seeker centres in The Netherlands. SUBJECTS:Hundred and sixteen children 2-12 years old (86% of the study cohort) provided a dietary history. METHOD:The die...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602501
更新日期：2007-01-01 00:00:00
abstract：:Dietary intake data of 43 Finnish rheumatoid arthritis patients were collected using 7-day food records. The subjects were randomized into a control and a vegan diet groups, consisting of 22 and 21 subjects, respectively. The subjects in the vegan diet group received an uncooked vegan diet ('living food') for 3 months...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1993-10-01 00:00:00
abstract：BACKGROUND:Studies have shown that depression relates to biomarkers of both short- and long-term polyunsaturated fatty acid (PUFA) intake. However, it is not known which of these two biomarkers has the closest relationship to depression. OBJECTIVE:To examine the relationship of depression with both adipose tissue and ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602413
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVES:To examine the association between breastfeeding pattern and growth in the first year of life. METHODS:A cross-sectional survey was carried out on 349 mothers with infants <12 months in a rural and a semi-urban community in Mangochi district, Malawi. Data on socio-demographic characteristics, infant weight,...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.148
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To assess the phytate intake and molar ratios of phytate to calcium, iron and zinc in the diets of people in China. DESIGN:2002 China Nationwide Nutrition and Health Survey is a cross-sectional nationwide representative survey on nutrition and health. The information on dietary intakes was collected using co...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602513
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To study the relation between sleep habits, nutritional status, growth and maturation in a group of African adolescent girls. The main hypothesis to be tested was that sleep length could be an effective way to spare energy, and thus malnourished girls sleep longer than normal girls. DESIGN:Three repeated yea...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601781
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Animal studies have demonstrated that soy isoflavones exert antidiabetic effects. However, evidence regarding the association between soyfood intake, a unique source of isoflavones, and type 2 diabetes remains inconclusive. This study assessed the relationship between habitual intakes of soyfoods ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2017.76
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Young Indian adults are at greater risk of overweight/obesity due to their high energy intake and sedentary lifestyle. Their energy requirement (ER) is based on their total energy expenditure (TEE) estimated from factorial method, which possibly overestimates their basal metabolic rate (BMR) and p...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00790-5
更新日期：2020-10-24 00:00:00
abstract：OBJECTIVE:To investigate the association between total alcohol intake and intake of different types of alcoholic beverages in relation to the risk of basal cell (BCC) and squamous cell (SCC) carcinoma of the skin. DESIGN:Prospective cohort study. SETTING:Follow-up data from a community-based skin cancer study in Aust...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602717
更新日期：2008-02-01 00:00:00
