Abstract:
INTRODUCTION:Meralgia paresthetica is a focal neuropathy caused by compression of the lateral femoral cutaneous nerve (LFCN). The disease can be difficult to assess by neurophysiological or imaging studies. METHODS:We studied 5 patients who presented to our neuromuscular clinic from April 2012 to December 2014 with a clinical suspicion of meralgia paresthetica and had skin biopsies with intraepidermal nerve fiber density (IENFD) evaluation. RESULTS:The mean age at onset was 37.2 (range 21-59) years. There were 4 women and 1 man. Two were obese, 2 wore tight jeans, and 1 had mild diabetes mellitus. IENFD was reduced in the symptomatic proximal thigh in all 5 patients and was also reduced in the asymptomatic thigh in 2 patients. It was normal in the distal leg in 4 patients. CONCLUSION:Meralgia paresthetica is associated with loss of small intraepidermal nerve fibers. Skin biopsy with IENFD evaluation may be a useful diagnostic tool for this disease.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Wongmek A,Shin S,Zhou Ldoi
10.1002/mus.25044subject
Has Abstractpub_date
2016-04-01 00:00:00pages
641-3issue
4eissn
0148-639Xissn
1097-4598journal_volume
53pub_type
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