Abstract:
INTRODUCTION:The involvement of small myelinated fibers in the early stages of diabetic neuropathy (DN) has been suggested, but few objective methods can identify minimal neuropathy. The purpose of this study was to determine whether there are differences in contact heat evoked potential (CHEP) parameters between healthy adults and diabetics with and without lower limb symptoms. METHODS:CHEP was recorded at the midline channels. A peak stimulating temperature of 51°C was applied to the dorsum of the foot and at a point 10 cm proximal to the lateral malleolus. RESULTS:There was a significant difference in N1-P1 amplitude in the three groups after stimulation of the dorsum of the foot (P = 0.028) and the point 10 cm proximal to the lateral malleolus (P = 0.006). DISCUSSION:CHEP can help to detect early A-delta fiber damage in diabetic patients with minimal neuropathy.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Wong MC,Chung JWdoi
10.1002/mus.22192subject
Has Abstractpub_date
2011-12-01 00:00:00pages
902-6issue
6eissn
0148-639Xissn
1097-4598journal_volume
44pub_type
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