Skeletal muscle expression of clathrin and mannose 6-phosphate receptor in experimental chloroquine-induced myopathy.

abstract：:A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...

journal_title：Muscle & nerve

authors： Krishnamurthy KB,Liu GT,Logigian EL

更新日期：1993-11-01 00:00:00

abstract：:Mechanical deformation of a peripheral nerve can evoke action potentials in sensory and motor axons. The generation of these impulses with brief stimuli (<0.5 s) and their relationship to the deformation conditions have not been systematically studied in human subjects. Controlled compression stimuli over a range of a...

journal_title：Muscle & nerve

authors： Clarke EC,McNulty PA,Macefield VG,Bilston LE

更新日期：2007-03-01 00:00:00

abstract：:McArdle disease is an autosomal recessive muscle glycogenosis. In the typical clinical presentation, only exercise-related symptoms are noted. Nevertheless, permanent weakness may occur, usually late in life. In this study we report on the clinical and genetic features of fixed muscle weakness in McArdle disease. Amon...

journal_title：Muscle & nerve

authors： Nadaj-Pakleza AA,Vincitorio CM,Laforêt P,Eymard B,Dion E,Teijeira S,Vietez I,Jeanpierre M,Navarro C,Stojkovic T

更新日期：2009-09-01 00:00:00

abstract：:Repetitive nerve stimulation (RNS) is a standard diagnostic procedure in myasthenia gravis (MG). Although RNS sensitivity is highest in weak muscles, RNS is easier to perform in distal muscles that are often not affected. Twenty-five patients with MG were assessed to compare the sensitivity of RNS of the nasalis muscl...

journal_title：Muscle & nerve

authors： Niks EH,Badrising UA,Verschuuren JJ,Van Dijk JG

更新日期：2003-08-01 00:00:00

abstract：:To better define electrophysiological abnormalities in myasthenia gravis (MG) patients with muscle-specific tyrosine kinase (MuSK) antibodies (Ab), we compared electrophysiological features of 14 MuSK Ab-positive, 73 acetylcholine receptor antibody (AChR Ab)-positive, and 22 MuSK and AChR Ab-negative (seronegative) pa...

journal_title：Muscle & nerve

authors： Oh SJ,Hatanaka Y,Hemmi S,Young AM,Scheufele ML,Nations SP,Lu L,Claussen GC,Wolfe GI

更新日期：2006-04-01 00:00:00

abstract：:Data are scarce relating to the plasticity with strength training of dynamic muscle performance in older humans. Hence, we investigated alterations in the torque-velocity relation with strength training in old age, and their origin. Knee extension and leg-press exercises were performed three times per week for 14 week...

journal_title：Muscle & nerve

authors： Reeves ND,Maganaris CN,Narici MV

更新日期：2005-03-01 00:00:00

abstract：:Median neuropathies proximal to the wrist are uncommon and usually result from penetrating injuries, fracture dislocation of the distal humerus, or compression by fibrous bands. A 66-year-old man suffered a comminuted fracture of the proximal humerus after a fall. Electrodiagnostic studies revealed a severe proximal m...

journal_title：Muscle & nerve

authors： Veilleux M,Richardson P

更新日期：2000-03-01 00:00:00

abstract：:The extensor of the second digit of the chicken wing (EDII) is a small, fast-twitch muscle susceptible to chicken muscular dystrophy and well suited for correlated studies of the morphology and physiology of identified nerve and muscle fibers. In cross section, the dystrophic EDII shows morphological abnormalities com...

journal_title：Muscle & nerve

authors： Gunther JS,Letinsky MS

更新日期：1982-01-01 00:00:00

abstract：:The Moberg Pick-Up Test is a standardized test for assessing hand dexterity. Although reduction of sensation in the hand occurs with aging, the effect of age on a subject's performance of the Moberg Pick-Up Test has not been examined. The primary goal of this study was to examine the impact of aging and, secondarily, ...

journal_title：Muscle & nerve

authors： Amirjani N,Ashworth NL,Gordon T,Edwards DC,Chan KM

更新日期：2007-06-01 00:00:00

abstract：:Electromyographic (EMG) recordings may serve an important role in predicting torque during repetitive activation of paralyzed muscle. We compared the initial M-wave to the subsequent M-waves of the same train under fatigued and recovered conditions in the paralyzed human soleus muscle. Sixteen individuals with chronic...

journal_title：Muscle & nerve

authors： Chang YJ,Shields RK

更新日期：2002-11-01 00:00:00

abstract：:The motor end-plate fine structure and distribution of junctional acetylcholine receptors (AChRs) in patients with amyotrophic lateral sclerosis (ALS) were studied. Morphometric analysis was carried out in 74 end-plates (92 innervated and 47 denuded postsynaptic regions) from 10 patients with ALS. AChR was studied by ...

journal_title：Muscle & nerve

authors： Tsujihata M,Hazama R,Yoshimura T,Satoh A,Mori M,Nagataki S

更新日期：1984-03-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) is a useful tool in the treatment of a variety of neuromuscular disorders. Though IVIg therapy is generally safe, hemolytic anemia is a potentially serious complication that is often overlooked, and is currently not listed in product inserts. We analyzed 45 patients who received IVIg ...

journal_title：Muscle & nerve

authors： Wilson JR,Bhoopalam H,Fisher M

更新日期：1997-09-01 00:00:00

abstract：:Electrophysiological studies were performed on the ventral tail nerve of adult rats following intraperitoneal injection of a crude extract of ciguatoxin from known toxic fish flesh. Ciguatoxin induced significant slowing of both mixed and motor nerve conduction velocities and also significant reductions in both motor ...

journal_title：Muscle & nerve

authors： Cameron J,Flowers AE,Capra MF

更新日期：1993-07-01 00:00:00

abstract：:The F-wave was used to estimate motor nerve conduction velocity (MNCV) along the proximal segment of the fastest axons of the deep peroneal nerve (anterior-horn cells to knee) in 13 patients with amyotrophic lateral sclerosis (ALS) and in 21 age- and sex-matched control subjects. Measurements were based on the shortes...

journal_title：Muscle & nerve

authors： Argyropoulos CJ,Panayiotopoulos CP,Scarpalezos S

更新日期：1978-11-01 00:00:00

abstract：INTRODUCTION:Lower limb strength has never been characterized separately for late-onset and adult myotonic dystrophy type 1 (DM1) phenotypes. METHODS:The purpose of this study was to: (1) describe and compare lower limb strength between the 2 DM1 phenotypes; and (2) compare the impairment profiles obtained from 2 asse...

journal_title：Muscle & nerve

authors： Petitclerc É,Hébert LJ,Mathieu J,Desrosiers J,Gagnon C

更新日期：2017-07-01 00:00:00

abstract：:Diabetic neuropathies are the most common type of neuropathies seen in clinical practice. These neuropathies can range clinically from asymptomatic to manifesting symptoms caused by motor, sensory, and autonomic nerve dysfunction. These neuropathies can affect the peripheral nervous system, pain receptors, cardiovascu...

journal_title：Muscle & nerve

authors： Patel K,Horak H,Tiryaki E

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Evaluation of nerve mechanical properties has the potential to improve assessment of nerve impairment. Shear wave velocity, as measured by using shear wave (SW) ultrasound elastography, is a promising indicator of nerve mechanical properties such as stiffness. However, elucidation of external factors that ...

journal_title：Muscle & nerve

authors： Rugel CL,Franz CK,Lee SSM

更新日期：2020-05-01 00:00:00

abstract：:We prospectively evaluated thalidomide-induced neuropathy using electrodiagnostic studies. Sixty-seven men with metastatic androgen-independent prostate cancer in an open-label trial of oral thalidomide underwent neurologic examinations and nerve conduction studies (NCS) prior to and at 3-month intervals during treatm...

journal_title：Muscle & nerve

authors： Molloy FM,Floeter MK,Syed NA,Sandbrink F,Culcea E,Steinberg SM,Dahut W,Pluda J,Kruger EA,Reed E,Figg WD

更新日期：2001-08-01 00:00:00

abstract：:Repetitive nerve stimulation (RNS) of the median nerve is rarely studied in myasthenia gravis (MG). We performed a retrospective analysis of RNS studies performed on 448 patients at our center between 2010 and 2016. Among 95 patients with MG, an abnormal decrement of the compound muscle action potential amplitude was ...

journal_title：Muscle & nerve

authors： Lee TH,Li Y

更新日期：2019-12-01 00:00:00

abstract：:A case study of a 50-year-old man who awakened from aortobifemoral bypass graft surgery with painful burning and numbness of the left foot is reported. Angiography showed embolic occlusion of the left popliteal artery proximal to the knee. Nerve conduction studies performed 1 year after occlusion showed loss or severe...

journal_title：Muscle & nerve

authors： Levin KH

更新日期：1989-10-01 00:00:00

abstract：:A careful monitoring of the accuracy of diagnosis in six cases of Guillain-Barre syndrome has shown that a substantial proportion of these patients initially diagnosed as having Guillain-Barre syndrome on the basis of characteristic clinical findings and an elevated level of protein in the spinal fluid had a neuropath...

journal_title：Muscle & nerve

authors： Feit H,Tindall RS,Glasberg M

更新日期：1982-02-01 00:00:00

abstract：:To study causes of obturator neuropathy and to correlate them with outcome, we retrospectively studied patients seen at the Mayo Clinic electromyography (EMG) laboratory from 1975 through 1999 with a diagnosis of obturator neuropathy. Twenty-two patients with obturator neuropathy were identified. The clinical outcome ...

journal_title：Muscle & nerve

authors： Sorenson EJ,Chen JJ,Daube JR

更新日期：2002-04-01 00:00:00

abstract：:Weakness is common in both hyper- and hypothyroidism, and skeletal muscle L-carnitine may play a role in this regard, as suggested by studies indicating abnormal levels of carnitine in serum and urine of patients with thyroid dysfunction. Skeletal muscle samples were obtained for carnitine analysis from control subjec...

journal_title：Muscle & nerve

authors： Sinclair C,Gilchrist JM,Hennessey JV,Kandula M

更新日期：2005-09-01 00:00:00

abstract：INTRODUCTION:Chorea-acanthocytosis (ChAc) is a rare autosomal recessive disease characterized by involuntary movements, seizures, cognitive changes, myopathy, and axonal neuropathy. METHODS:We report a patient who presented with gait impairment and dysarthria. Clinical and neurophysiological assessment disclosed upper...

journal_title：Muscle & nerve

authors： Neutel D,Miltenberger-Miltenyi G,Silva I,de Carvalho M

更新日期：2012-02-01 00:00:00

abstract：:Mutations in CLCN1, the gene encoding the ClC-1 chloride channel in skeletal muscle, lead to myotonia congenita. The effects on the intramembranous channel forming domains have been investigated more than that at the intracellular C-terminus. We have performed a mutation screen involving the whole CLCN1 gene of patien...

journal_title：Muscle & nerve

authors： Chen L,Schaerer M,Lu ZH,Lang D,Joncourt F,Weis J,Fritschi J,Kappeler L,Gallati S,Sigel E,Burgunder JM

更新日期：2004-05-01 00:00:00

abstract：INTRODUCTION:Onabotulinum toxin serotype A (BT-A) is used for a variety of motor and sensory disorders related to abnormal muscle activity. METHODS:We developed a high-resolution rodent model to allow precise determination of the effect of BT-A dose (measured in units) and injectate volume (measured in μl) on the effi...

journal_title：Muscle & nerve

authors： Hulst JB,Minamoto VB,Lim MB,Bremner SN,Ward SR,Lieber RL

更新日期：2014-05-01 00:00:00

abstract：:Voluntary and stimulation single-fiber electromyography were performed in the extensor digitorum communis muscle of 15 myasthenic patients. The increase in mean and individual mean consecutive difference as well as the proportion of blocking in the volitional activation were greater than in the stimulation method. The...

journal_title：Muscle & nerve

authors： Murga L,Sánchez F,Menéndez C,Castilla JM

更新日期：1998-08-01 00:00:00

abstract：INTRODUCTION:In compressive neuropathies, large myelinated nerve fibers are generally thought to be more susceptible. In this study, we investigated small myelinated Aδ and unmyelinated C fiber function in patients with mild, moderate, and severe carpal tunnel syndrome. METHODS:Forty-four healthy controls and 81 carpa...

journal_title：Muscle & nerve

authors： Clarke C,Christensen C,Curran MWT,Chan KM

更新日期：2017-10-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) is a degenerative disease of skeletal, respiratory, and cardiac muscles caused by defects in the dystrophin gene. More recently, brain involvement has been verified. Mitochondrial dysfunction and oxidative stress may underlie the pathophysiology of DMD. In this study we ev...

journal_title：Muscle & nerve

authors： Comim CM,Hoepers A,Ventura L,Freiberger V,Dominguini D,Mina F,Mendonça BP,Scaini G,Vainzof M,Streck EL,Quevedo J

更新日期：2016-01-01 00:00:00

abstract：:Bcl-2 and Bax immunohistochemistry was examined in the skeletal muscle of rats after cutting the sciatic nerve, as a model of denervation and reinnervation, and in the anterior tibialis muscle of rats after an intramuscular injection of metoclopramide, as a model of necrosis and regeneration of muscle fibers, to bette...

journal_title：Muscle & nerve

authors： Olivé M,Ferrer I

更新日期：2000-12-01 00:00:00