Sources of error in the diagnosis of Guillain-Barre syndrome.

Abstract:

:A careful monitoring of the accuracy of diagnosis in six cases of Guillain-Barre syndrome has shown that a substantial proportion of these patients initially diagnosed as having Guillain-Barre syndrome on the basis of characteristic clinical findings and an elevated level of protein in the spinal fluid had a neuropathy caused by another etiology. The pitfalls in the laboratory and clinical diagnosis of disorders that were confused with Guillain-Barre syndrome were several: the pattern of neurological dysfunction in the Guillain-Barre syndrome was not unique to that disorder; no specific laboratory test existed to confirm the diagnosis of Guillain-Barre syndrome; and the laboratory diagnosis of other causes of similar neurological disorders (especially heavy metal intoxication) depended upon tests that are very unreliable.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Feit H,Tindall RS,Glasberg M

doi

10.1002/mus.880050206

subject

Has Abstract

pub_date

1982-02-01 00:00:00

pages

111-7

issue

2

eissn

0148-639X

issn

1097-4598

journal_volume

5

pub_type

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