Contribution of the Na(+)-K+ pump to membrane potential in familial periodic paralysis.

abstract：INTRODUCTION:In this study we estimated the costs paid by U.S. health plans for treating myasthenia gravis (MG) in 2009 and determined the major cost drivers. METHODS:One hundred thirteen MG patients were matched by propensity scores with 339 non-MG patients from a comprehensive health-care insurance database. The mea...

journal_title：Muscle & nerve

authors： Guptill JT,Sharma BK,Marano A,Soucy A,Krueger A,Sanders DB

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Valosin-containing protein (VCP) variants that affect muscle, bone, and the nervous system are termed multisystem proteinopathy. VCP myopathy is manifested as limb-girdle weakness, distal weakness and scapuloperoneal weakness. METHODS:We reviewed clinical, genetic, and muscle biopsy data from 6 members of...

journal_title：Muscle & nerve

authors： Guo X,Zhao Z,Shen H,Qi B,Li N,Hu J

更新日期：2019-03-01 00:00:00

abstract：:Six members originating from two families with hereditary motor and sensory neuropathy (hypertrophic and neuronal types) were noted to have enlarged calf muscles. Muscle computed tomography revealed that muscle enlargement in the propositus of the family with the hypertrophic type of HMSN was due to an increase in mus...

journal_title：Muscle & nerve

authors： De Visser M,Hoogendijk JE,Ongerboer BW,Verbeeten BJ Jr

更新日期：1990-01-01 00:00:00

abstract：:Injection of low-dose arachidonic acid into the rat femoral artery occludes the vasa nervorum of the tibial nerve and produces focal and generalized ischemia with transient effects on nerve conduction. Across a severely ischemic segment of the proximal tibial nerve there is a marked fall in amplitude of the compound m...

journal_title：Muscle & nerve

authors： Parry GJ,Linn DJ

更新日期：1986-05-01 00:00:00

abstract：:The purpose of this study was to investigate whether the previously demonstrated heterogeneity of myosin heavy chain (MHC) in type 2B fibers of the superficial portion of the lateral gastrocnemius (SLG) muscle of the rat may be due to presence of type 2D/X fibers. Immunohistochemical identification of MHC heterogeneit...

journal_title：Muscle & nerve

authors： Sawchak JA,Leung B,Shafiq SA

更新日期：1992-12-01 00:00:00

abstract：INTRODUCTION:In this study we aimed to identify prognostic factors of ulnar neuropathy at the elbow (UNE) and developed a scoring system to establish the prognosis. METHODS:We collected baseline clinical, electrophysiologic, and ultrasonographic data from 2 cohorts. The outcomes for all patients were determined on fol...

journal_title：Muscle & nerve

authors： Beekman R,Zijlstra W,Visser LH

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:The current practice of single-fiber electromyography (SFEMG) requires that 20 fiber pairs with normal jitter be collected to exclude myasthenia gravis (MG). We applied principles of futility analysis from clinical trials in an attempt to reduce that requirement. METHODS:We utilized conditional power futi...

journal_title：Muscle & nerve

authors： Narayanaswami P,Pantoja-Galicia N,Betensky RA,Rutkove SB

更新日期：2012-04-01 00:00:00

abstract：INTRODUCTION:Widespread musculoskeletal pain is a well-known symptom of myotonic dystrophy type 2 (DM2), but so far it has been addressed in only a few studies. METHODS:A postal survey for all traceable DM2 patients (n = 132) was conducted. A specific questionnaire, and severity and interference subscales of the Brief...

journal_title：Muscle & nerve

authors： Suokas KI,Haanpää M,Kautiainen H,Udd B,Hietaharju AJ

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Information related to the long-term follow-up of neuropathy in patients with familial amyloid polyneuropathy after liver transplantation is still scarce. METHODS:We describe the neuropathic features of 3 patients with the transthyretin Val30Met mutation. Each patient underwent liver transplantation at an...

journal_title：Muscle & nerve

authors： Koike H,Hashimoto R,Tomita M,Kawagashira Y,Iijima M,Nakamura T,Watanabe H,Kamei H,Kiuchi T,Sobue G

更新日期：2012-12-01 00:00:00

abstract：:A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...

journal_title：Muscle & nerve

authors： Krishnamurthy KB,Liu GT,Logigian EL

更新日期：1993-11-01 00:00:00

abstract：INTRODUCTION:We describe the nerve ultrasound findings in patients with type II diabetes mellitus who have neuropathic symptoms and signs. METHODS:Fifty-five healthy controls and 44 diabetic patients underwent clinical, sonographic, and electrophysiological evaluation. Patients were studied at a mean of 14.3 years aft...

journal_title：Muscle & nerve

authors： Pitarokoili K,Kerasnoudis A,Behrendt V,Labedi A,Ayzenberg I,Gold R,Yoon MS

更新日期：2016-06-01 00:00:00

abstract：:Muscle weakness in myasthenia gravis is due to autoantibody-induced loss of functional acetylcholine receptors (AChR). About 15% of myasthenia gravis patients, however, do not have detectable anti-AChR antibodies. To investigate the effect of their plasma immunoglobulins on neuromuscular transmission, mice were inject...

journal_title：Muscle & nerve

authors： Burges J,Vincent A,Molenaar PC,Newsom-Davis J,Peers C,Wray D

更新日期：1994-12-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess whether peripheral neuropathy is a feature of glycogen storage disease type IIIa (GSD IIIa) in adult patients. METHODS:Medical records of a cohort of adult GSD IIIa patients who underwent electromyography (EMG) and nerve conduction studies (NCS) were reviewed, and the r...

journal_title：Muscle & nerve

authors： Herlin B,Laforět P,Labrune P,Fournier E,Stojkovic T

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:Ulnar neuropathy at the elbow (UNE) is a common peripheral compression neuropathy and, in most cases, occurs at 2 sites, the retroepicondylar groove or the cubital tunnel. With regard to a potential therapeutic approach with perineural corticosteroid injection, the aim of this study was to evaluate the dis...

journal_title：Muscle & nerve

authors： Hamscha UM,Tinhofer I,Heber S,Grisold W,Weninger WJ,Meng S

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Our aim in this study was to determine whether intravenous immunoglobulin (IVIg) or plasma exchange (PLEx) for treatment of neurologic disease is a trigger for thrombotic events. METHODS:Using administrative data from 2005 to 2014, we identified index admissions for thrombotic events. We performed case-cr...

journal_title：Muscle & nerve

authors： Jin PH,Shin SC,Dhamoon MS

更新日期：2020-09-01 00:00:00

abstract：:Calmodulin levels have been assessed in whole muscle and primary culture extracts in order to examine the relationship between calmodulin and the accumulation of calcium in dystrophic hamster muscle tissues. Significant decreases in both normal and dystrophic skeletal muscle, tongue, and heart calmodulin levels were o...

journal_title：Muscle & nerve

authors： Klamut HJ,Kotarba JA,Strickland KP

更新日期：1987-01-01 00:00:00

abstract：:The aim of this study was to define normal ranges of histological features in pediatric muscle in comparison with muscle demonstrating inflammatory changes. Sixteen pediatric muscle biopsy samples, considered normal by standard histology, were analyzed for the presence of inflammatory cells, and the expression of neon...

journal_title：Muscle & nerve

authors： Varsani H,Newton KR,Li CK,Harding B,Holton JL,Wedderburn LR

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Cerebral palsy (CP) is associated with reduced muscle volumes, but previous studies have reported deficits in only a small number of muscles. The extent of volume deficits across lower limb muscles is not known. This study presents an imaging-based assessment of muscle volume and length deficits in 35 lowe...

journal_title：Muscle & nerve

authors： Handsfield GG,Meyer CH,Abel MF,Blemker SS

更新日期：2016-06-01 00:00:00

abstract：:The findings in two cases of congenital myasthenia investigated by intercostal muscle biopsy are presented. The first case, a 16-year-old boy, showed reduced miniature endplate potential amplitude and normal 125I-alpha-bungarotoxin binding to postsynaptic acetylcholine receptors. Muscle biopsy and endplate ultrastruct...

journal_title：Muscle & nerve

authors： Lecky BR,Morgan-Hughes JA,Murray NM,Landon DN,Wray D,Prior C

更新日期：1986-03-01 00:00:00

abstract：:We reviewed results of immunotherapy in patients with demyelinating motor neuropathy (DMN), and found that patients over 50 years of age at onset responded poorly, and younger patients responded variably to intervention. We suggest that patients with DMN be given a guarded prognosis, particularly if >50 years of age a...

journal_title：Muscle & nerve

authors： Markson L,Janzen D,Bril V

更新日期：1998-12-01 00:00:00

abstract：:The effect of endurance training on muscle electrical activity during general exercise testing was investigated in physically active patients with chronic obstructive pulmonary disease (COPD). Before and after rehabilitation, patients performed identical incremental exercise tests. Pulmonary gas exchange, venous lacta...

journal_title：Muscle & nerve

authors： Gosselin N,Lambert K,Poulain M,Martin A,Préfaut C,Varray A

更新日期：2003-12-01 00:00:00

abstract：:A link between the cardioprotective benefits of pharmacological preconditioning and natural mammalian hibernation is considered to involve the cellular activation of opioid receptors and subsequent opening of K(ATP) channels. In previous studies, we have demonstrated the protective effects of specific delta-opioid ago...

journal_title：Muscle & nerve

authors： Hong J,Sigg DC,Coles JA Jr,Oeltgen PR,Harlow HJ,Soule CL,Iaizzo PA

更新日期：2005-08-01 00:00:00

abstract：:Comparison was made between simultaneous recordings of the electromyogram (EMG) and acoustic myogram (AMG) signals and the torque produced by the lumbar erectores spinae muscles of three healthy subjects while they performed isometric contractions. Repeatability of each signal was studied. The AMG had a relationship t...

journal_title：Muscle & nerve

authors： Stokes IA,Moffroid MS,Rush S,Haugh LD

更新日期：1988-04-01 00:00:00

abstract：:Involuntary muscle contractions are common after spinal cord injury (SCI). Increased sensitivity to Ia muscle afferent input may contribute to the development of these spasms. Since tendon vibration results in a period of postactivation depression of the Ia synapse, we sought to determine whether Achilles tendon vibra...

journal_title：Muscle & nerve

authors： Butler JE,Godfrey S,Thomas CK

更新日期：2006-05-01 00:00:00

abstract：:The degree of upper extremity active range of motion provided by an admittance control robot compared with a commercially available passive arm support for individuals with DMD who have limited arm function was investigated in this study. The reachable workspace evaluation was used to assess active range of motion pro...

journal_title：Muscle & nerve

authors： Corrigan MC,Foulds RA

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The goals of this study were to determine whether serum concentrations of endocannabinoids (eCB) and related lipids predict disease status in patients with amyotrophic lateral sclerosis (ALS) relative to healthy controls, and whether concentrations correlate with disease duration and severity. METHODS:Serum...

journal_title：Muscle & nerve

authors： Carter GT,McLaughlin RJ,Cuttler C,Sauber GJ,Weeks DL,Hillard CJ,Weiss MD

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Documentation of peripheral nerve demyelination is an important part of the chronic inflammatory demyelinating polyneuropathy (CIDP) diagnostic process. METHODS:We performed a retrospective analysis of patients referred with a diagnosis of CIDP who were found to have a different condition. Electrodiagnost...

journal_title：Muscle & nerve

authors： Allen JA,Ney J,Lewis RA

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Slowly progressive, genetic neuromuscular diseases (gNMDs) often lead to important motor deficiencies and functional limitations. The Quality of Life in Genetic Neuromuscular Disease Questionnaire (QoL-gNMD) is a new health-related quality-of-life questionnaire developed for these patients. The purpose of ...

journal_title：Muscle & nerve

authors： Dany A,Rapin A,Lavrard B,Saoût V,Réveillère C,Bassez G,Tiffreau V,Péréon Y,Sacconi S,Eymard B,Dramé M,Jolly D,Novella JL,Hardouin JB,Boyer FC

更新日期：2017-12-01 00:00:00

abstract：:Exercise intolerance with myalgia, muscle stiffness, and recurrent rhabdomyolysis due to mutations in the DMD gene can mimic metabolic myopathies leading to delayed or inaccurate diagnoses. In this retrospective chart review, we report 3 unrelated boys with exertional myalgia, muscle stiffness, myoglobinuria, and norm...

journal_title：Muscle & nerve

authors： Veerapandiyan A,Shashi V,Jiang YH,Gallentine WB,Schoch K,Smith EC

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Tarsal tunnel syndrome (TTS) arises from tibial nerve damage under the flexor retinaculum of the fibro-osseus tunnel at the medial malleolus. It is notoriously difficult to diagnose, as many other foot pathologies result in a similar clinical picture. We examined the additional value of nerve ultrasound in...

journal_title：Muscle & nerve

authors： Samarawickrama D,Therimadasamy AK,Chan YC,Vijayan J,Wilder-Smith EP

更新日期：2016-06-01 00:00:00