Fasciculation potentials in healthy people.

abstract：:In a woman with a slowly progressive adult onset proximal myopathy, muscle biopsy showed storage of PAS positive material in type 1 fibers. This material consisted of a branched chain polysaccharide associated with a mucoprotein. No abnormality of glycogen-pathway enzymes was detected. This suggested that this polysac...

journal_title：Muscle & nerve

authors： Thompson AJ,Swash M,Cox EL,Ingram DA,Gray A,Schwartz MS

更新日期：1988-04-01 00:00:00

abstract：:Limb-girdle muscular dystrophy 2D (LGMD2D) is caused by mutations in the alpha-sarcoglycan gene (SGCA). The most frequently reported mutation, 229CGC>TGC (R77C) in exon 3 of SGCA, results in the substitution of arginine by cysteine. We present here the clinical, immunohistochemical, and genetic data of 11 Finnish pati...

journal_title：Muscle & nerve

authors： Hackman P,Juvonen V,Sarparanta J,Penttinen M,Aärimaa T,Uusitalo M,Auranen M,Pihko H,Alén R,Junes M,Lönnqvist T,Kalimo H,Udd B

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:The contribution of cranial and thoracic region electromyography (EMG) to diagnostic criteria for amyotrophic lateral sclerosis (ALS) has not been evaluated. METHODS:Clinical and EMG data from each craniospinal region were retrospectively assessed in 470 patients; 214 had ALS. Changes to diagnostic classi...

journal_title：Muscle & nerve

authors： Jenkins TM,Alix JJ,Kandler RH,Shaw PJ,McDermott CJ

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to investigate in vivo median nerve longitudinal mobility in different segments of the carpal tunnel associated with active finger motion in carpal tunnel syndrome (CTS) patients in a comparison with healthy controls. METHODS:Eleven healthy volunteers and 11 CTS patients part...

journal_title：Muscle & nerve

authors： Yao Y,Grandy E,Evans PJ,Seitz WH Jr,Li ZM

更新日期：2020-10-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder with complex biology and significant clinical heterogeneity. Many preclinical and early phase ALS clinical trials have yielded promising results that could not be replicated in larger phase 3 confirmatory trials. One reason for the lack o...

journal_title：Muscle & nerve

authors： Goyal NA,Berry JD,Windebank A,Staff NP,Maragakis NJ,van den Berg LH,Genge A,Miller R,Baloh RH,Kern R,Gothelf Y,Lebovits C,Cudkowicz M

更新日期：2020-08-01 00:00:00

abstract：:Task-dependent differences in the facilitation of motor evoked potentials (MEPs) following cortex stimulation were studied in a proximal (deltoid) and a distal muscle (abductor digiti minimi; ADM) in 23 healthy subjects during both dynamic and steady contractions of the target muscle under isometric and under nonisome...

journal_title：Muscle & nerve

authors： Arányi Z,Mathis J,Hess CW,Rösler KM

更新日期：1998-10-01 00:00:00

abstract：:Several approaches to treat laminin alpha2 chain-deficient congenital muscular dystrophy (MDC1A) in mouse models have been undertaken. Most have shown promising results in young animals. However, older animals have only been characterized to some extent. Herein we analyze the lifespan of laminin alpha2 chain-deficient...

journal_title：Muscle & nerve

authors： Gawlik KI,Durbeej M

更新日期：2010-07-01 00:00:00

abstract：:Ocular movements and coordination require complex and integrated functions of somatic and autonomic nervous systems. Neurological disorders affecting these nervous systems may cause ocular dysfunction involving extraocular muscles and pupils. In this article, the prevalence, clinical presentations, and management of o...

journal_title：Muscle & nerve

authors： Evliyaoglu F,Karadag R,Burakgazi AZ

更新日期：2012-11-01 00:00:00

abstract：:The cross-sectional area of the fibers of hindlimb muscles of rats increased 10-40 times during the first 6 weeks after birth. Denervation at birth stopped the growth of the muscle fibers. The number of satellite cells decreased, and eventually all fibers vanished. Reinnervation, if any, was poor. Partial denervation ...

journal_title：Muscle & nerve

authors： Schmalbruch H

更新日期：1990-05-01 00:00:00

abstract：INTRODUCTION:In this study we present a reproducible technique to assess motor recovery after nerve injury via neuromuscular junction (NMJ) immunostaining and electrodiagnostic testing. METHODS:Wild-type mice underwent sciatic nerve transection with repair. Hindlimb muscles were collected for microscopy up to 30 weeks...

journal_title：Muscle & nerve

authors： Vannucci B,Santosa KB,Keane AM,Jablonka-Shariff A,Lu CY,Yan Y,MacEwan M,Snyder-Warwick AK

更新日期：2019-11-01 00:00:00

abstract：:The lack of effective therapy for many of the chronic neuromuscular diseases such as amyotrophic lateral sclerosis, hereditary motor sensory neuropathy (Charcot-Marie-Tooth disease), spinocerebellar degenerations and idiopathic polyneuropathy has led to a search for substances that may stimulate peripheral nerve regen...

journal_title：Muscle & nerve

authors： Bradley WG

更新日期：1990-09-01 00:00:00

abstract：:To determine if short TI (time to inversion) recovery (STIR) magnetic resonance imaging (MRI) is useful in assessing lower extremity (LE) denervation in subacute lumbar radiculopathy (LR), 25 subjects underwent lumbar spine MRI, LE STIR MRI and needle electromyography (EMG). In 23 (92%) subjects there was a positive c...

journal_title：Muscle & nerve

authors： Carter GT,Fritz RC

更新日期：1997-09-01 00:00:00

abstract：INTRODUCTION:Onabotulinum toxin serotype A (BT-A) is used for a variety of motor and sensory disorders related to abnormal muscle activity. METHODS:We developed a high-resolution rodent model to allow precise determination of the effect of BT-A dose (measured in units) and injectate volume (measured in μl) on the effi...

journal_title：Muscle & nerve

authors： Hulst JB,Minamoto VB,Lim MB,Bremner SN,Ward SR,Lieber RL

更新日期：2014-05-01 00:00:00

abstract：:Peripheral nerve lesions are sometimes associated with focal dystonia. We diagnosed ulnar neuropathy in 28 of 73 (40%) cases of occupational cramp in musicians. Focal slowing of ulnar conduction across the elbow was identified in 15 of 19 (79%) patients using the near nerve technique and in 5 of 17 (29%) patients usin...

journal_title：Muscle & nerve

authors： Charness ME,Ross MH,Shefner JM

更新日期：1996-04-01 00:00:00

abstract：INTRODUCTION:Our aim in this study was to determine whether intravenous immunoglobulin (IVIg) or plasma exchange (PLEx) for treatment of neurologic disease is a trigger for thrombotic events. METHODS:Using administrative data from 2005 to 2014, we identified index admissions for thrombotic events. We performed case-cr...

journal_title：Muscle & nerve

authors： Jin PH,Shin SC,Dhamoon MS

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Diagnosing cervical radiculopathy (CR) can be difficult because of symptomatic overlap with peripheral neuropathies. In this retrospective observational study, we aimed to determine whether short-tau inversion recovery (STIR) magnetic resonance imaging (MRI) sequences are useful for detecting signs of denerv...

journal_title：Muscle & nerve

authors： Yoshida T,Suwazono S,Sueyoshi T,Izumi Y,Nodera H

更新日期：2020-12-13 00:00:00

abstract：:To determine which sensory nerve conduction studies (S-NCS) are helpful in detecting supraclavicular axon loss brachial plexopathies, we selected 53 cases (of 417 reviewed) in whom complicating factors were absent and which, by needle electrode examination findings, involved only a single "truncal" element (upper, mid...

journal_title：Muscle & nerve

authors： Ferrante MA,Wilbourn AJ

更新日期：1995-08-01 00:00:00

abstract：:The electrical and mechanical properties of paralyzed human thenar muscles were measured in response to supramaximal stimulation of the median nerve in individuals with chronic cervical spinal cord injury. These data were compared to those recorded from control muscles. Spontaneous motor unit activity was common in pa...

journal_title：Muscle & nerve

authors： Thomas CK

更新日期：1997-07-01 00:00:00

abstract：:Peripheral neuropathy marked by reduced nerve conduction velocities was found in four unrelated children, between the ages of 15 months and 9 years, whose autopsies revealed Leigh's subacute necrotizing encephalomyelopathy. Sural nerve biopsies disclosed primary demyelination and remyelination, as well as loss of myel...

journal_title：Muscle & nerve

authors： Goebel HH,Bardosi A,Friede RL,Kohlschütter A,Albani M,Siemes H

更新日期：1986-02-01 00:00:00

abstract：:A stand-alone ultrasound shear wave imaging technology has been developed to quantify and visualize Young's modulus distribution by remotely applying ultrasound radiation force and tracking the resulting microvibrations in soft tissues with ultrafast ultrasound imaging. We report the first preliminary data that detect...

journal_title：Muscle & nerve

authors： Shinohara M,Sabra K,Gennisson JL,Fink M,Tanter M

更新日期：2010-09-01 00:00:00

abstract：:Diabetic neuropathies are the most common type of neuropathies seen in clinical practice. These neuropathies can range clinically from asymptomatic to manifesting symptoms caused by motor, sensory, and autonomic nerve dysfunction. These neuropathies can affect the peripheral nervous system, pain receptors, cardiovascu...

journal_title：Muscle & nerve

authors： Patel K,Horak H,Tiryaki E

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Motor unit number estimates (MUNEs) provide important information in health, aging, and disease, and can be determined using decomposition-enhanced spike-triggered averaging (DE-STA). Discrimination of surface-detected motor unit potentials (S-MUPs) has been limited to contractile forces of ∽30% maximum vo...

journal_title：Muscle & nerve

authors： Stevens DE,Harwood B,Power GA,Doherty TJ,Rice CL

更新日期：2014-07-01 00:00:00

abstract：:Electromyographic examination of the deeper external anal sphincter (EAS) muscle is far more uncomfortable than of the subcutaneous muscle, so we tested the need for its examination. We compared the findings in 85 paired examinations of ipsilateral subcutaneous and deeper EAS muscles in 67 patients with a cauda equina...

journal_title：Muscle & nerve

authors： Podnar S

更新日期：2003-09-01 00:00:00

abstract：:We used peristimulus time histograms (PSTHs) to estimate characteristics of the composite excitatory postsynaptic potentials (EPSPs) generated at the anterior horn cell by a descending cortical volley induced by subthreshold transcranial magnetic stimuli in 11 normal subjects, 9 patients with DNA-confirmed Kennedy's d...

journal_title：Muscle & nerve

authors： Weber M,Eisen A

更新日期：1999-03-01 00:00:00

abstract：INTRODUCTION:The risk of cancer in patients diagnosed with myotonic dystrophy (DM) is reported for the homogeneous Utah population. METHODS:Clinical data accessed from the largest Utah healthcare providers have been record-linked to the Utah Population Database, a population-based resource also linked to the Utah Canc...

journal_title：Muscle & nerve

authors： Abbott D,Johnson NE,Cannon-Albright LA

更新日期：2016-10-01 00:00:00

abstract：:Toxoplasma gondii encysts in skeletal muscle. Although only rarely found at muscle biopsy, this parasite has previously been regarded as a possible cause of polymyositis. We report a case of biopsy-proven toxoplasmic myositis in a non-HIV-infected patient that led to recognition of idiopathic CD4 lymphocytopenia (ICL)...

journal_title：Muscle & nerve

authors： Plonquet A,Bassez G,Authier FJ,Dray JM,Farcet JP,Gherardi RK

更新日期：2003-06-01 00:00:00

abstract：:To study causes of obturator neuropathy and to correlate them with outcome, we retrospectively studied patients seen at the Mayo Clinic electromyography (EMG) laboratory from 1975 through 1999 with a diagnosis of obturator neuropathy. Twenty-two patients with obturator neuropathy were identified. The clinical outcome ...

journal_title：Muscle & nerve

authors： Sorenson EJ,Chen JJ,Daube JR

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:An open-label trial suggested that valproic acid (VPA) improved strength in adults with spinal muscular atrophy (SMA). We report a 12-month, double-blind, cross-over study of VPA in ambulatory SMA adults. METHODS:There were 33 subjects, aged 20–55 years, included in this investigation. After baseline asse...

journal_title：Muscle & nerve

authors： Kissel JT,Elsheikh B,King WM,Freimer M,Scott CB,Kolb SJ,Reyna SP,Crawford TO,Simard LR,Krosschell KJ,Acsadi G,Schroth MK,D'Anjou G,LaSalle B,Prior TW,Sorenson S,Maczulski JA,Swoboda KJ,Project Cure Spinal Muscular Atr

更新日期：2014-02-01 00:00:00

abstract：:We report three patients with inflammatory myopathy who presented clinically with weakness and wasting of only one limb. The myopathy progressed over 6 months and 5 years, respectively, in two patients and was stable after 8 years in the third patient. One patient had a skin rash. Serum CK was elevated in the two pati...

journal_title：Muscle & nerve

authors： Lederman RJ,Salanga VD,Wilbourn AJ,Hanson MR,Dudley AW Jr

更新日期：1984-02-01 00:00:00

abstract：:In a reported patient with myopathic carnitine deficiency, addition of exogenous carnitine to muscle homogenates failed to correct palmitate oxidation, and oral carnitine was of no clinical benefit. In a muscle biopsy from this patient, we found that, in contrast to the marked deficiency of free carnitine (3% of norma...

journal_title：Muscle & nerve

authors： Trevisan CP,Reichmann H,DeVivo DC,DiMauro S

更新日期：1985-10-01 00:00:00