Abstract:
:Toxoplasma gondii encysts in skeletal muscle. Although only rarely found at muscle biopsy, this parasite has previously been regarded as a possible cause of polymyositis. We report a case of biopsy-proven toxoplasmic myositis in a non-HIV-infected patient that led to recognition of idiopathic CD4 lymphocytopenia (ICL), a rare condition typically associated with opportunistic infections. Interestingly, the CD25(+) subset that corresponds to the CD4(+) regulatory T cells controlling autoimmune processes was lacking. Steroid and antiprotozoal therapy led to recovery.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Plonquet A,Bassez G,Authier FJ,Dray JM,Farcet JP,Gherardi RKdoi
10.1002/mus.10376subject
Has Abstractpub_date
2003-06-01 00:00:00pages
761-5issue
6eissn
0148-639Xissn
1097-4598journal_volume
27pub_type
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