Toxoplasmic myositis as a presenting manifestation of idiopathic CD4 lymphocytopenia.

Abstract:

:Toxoplasma gondii encysts in skeletal muscle. Although only rarely found at muscle biopsy, this parasite has previously been regarded as a possible cause of polymyositis. We report a case of biopsy-proven toxoplasmic myositis in a non-HIV-infected patient that led to recognition of idiopathic CD4 lymphocytopenia (ICL), a rare condition typically associated with opportunistic infections. Interestingly, the CD25(+) subset that corresponds to the CD4(+) regulatory T cells controlling autoimmune processes was lacking. Steroid and antiprotozoal therapy led to recovery.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Plonquet A,Bassez G,Authier FJ,Dray JM,Farcet JP,Gherardi RK

doi

10.1002/mus.10376

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

761-5

issue

6

eissn

0148-639X

issn

1097-4598

journal_volume

27

pub_type

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