A review of techniques employed to estimate the number of motor units in a muscle.

abstract：INTRODUCTION:Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders. METHODS:We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of cl...

journal_title：Muscle & nerve

authors： Lieba-Samal D,Jengojan S,Kasprian G,Wöber C,Bodner G

更新日期：2016-12-01 00:00:00

abstract：:Multifocal motor neuropathy (MMN) is now a well-defined purely motor multineuropathy characterized by the presence of multifocal partial motor conduction blocks (CB), frequent association with anti-GM1 IgM antibodies, and usually a good response to high-dose intravenous immunoglobulin (IVIg) therapy. However, several ...

journal_title：Muscle & nerve

authors： Nobile-Orazio E,Cappellari A,Priori A

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:Doppler ultrasonography (DU) has recently been shown to be useful in imaging carpal tunnel syndrome (CTS). In this study, we aim to characterize the changes seen after exercise and electrical stimulation. METHODS:Five patients with CTS were recruited with 5 age-matched subjects. DU was used to visualize t...

journal_title：Muscle & nerve

authors： Ng ES,Ng KW,Wilder-Smith EP

更新日期：2013-01-01 00:00:00

abstract：:Because of their central role in muscle development and maintenance, MEF2 family members represent excellent candidate effectors of the muscle pathology in myotonic dystrophy (DM). We investigated the expression and alternative splicing of all four MEF2 genes in muscle from neuromuscular disorder (NMD) patients, inclu...

journal_title：Muscle & nerve

authors： Bachinski LL,Sirito M,Böhme M,Baggerly KA,Udd B,Krahe R

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:We aimed to investigate whether sonographic peripheral cross-sectional nerve area (CSA) and progranulin (PGRN), a neuritic growth factor, are related to each other and whether they interact to predict clinical and paraclinical measures in amyotrophic lateral sclerosis (ALS). METHODS:We included 55 ALS pat...

journal_title：Muscle & nerve

authors： Schreiber S,Debska-Vielhaber G,Abdulla S,Machts J,Schreiber F,Kropf S,KÖrtvelyessy P,KÖrner S,Kollewe K,Petri S,Dengler R,Kunz WS,Nestor PJ,Vielhaber S

更新日期：2018-02-01 00:00:00

abstract：:The Moberg Pick-Up Test is a standardized test for assessing hand dexterity. Although reduction of sensation in the hand occurs with aging, the effect of age on a subject's performance of the Moberg Pick-Up Test has not been examined. The primary goal of this study was to examine the impact of aging and, secondarily, ...

journal_title：Muscle & nerve

authors： Amirjani N,Ashworth NL,Gordon T,Edwards DC,Chan KM

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:The p.A1156T mutation alters the function of the voltage-gated sodium channel Nav1.4 on the muscle sarcolemma, causing a channelopathy without overt myotonia or periodic paralysis but with myalgic pain. METHODS:A postal survey was conducted to assess the prevalence and characteristics of pain and related ...

journal_title：Muscle & nerve

authors： Suokas K,Palmio J,Sandell S,Udd B,Hietaharju A

更新日期：2018-06-01 00:00:00

abstract：:The double-step technique of repetitive nerve stimulation was compared with repetitive nerve stimulation to a distal and a proximal muscle and with single fiber needle electromyography in 10 patients with myasthenia gravis. We conclude that the double-step technique is slightly more sensitive than repetitive nerve sti...

journal_title：Muscle & nerve

authors： Gilchrist JM,Sanders DB

更新日期：1987-03-01 00:00:00

abstract：:Body weight-supported treadmill (BWST) training has been shown to improve ambulatory capacity in persons with a spinal cord injury (SCI); however, the effect that BWST training has on skeletal muscle phenotype is unknown. We aimed to determine whether 6 months (three sessions/week) of BWST training in neurologically s...

journal_title：Muscle & nerve

authors： Stewart BG,Tarnopolsky MA,Hicks AL,McCartney N,Mahoney DJ,Staron RS,Phillips SM

更新日期：2004-07-01 00:00:00

abstract：:We have examined the clinical features of patients with femoral neuropathy and the factors that influence the prognosis. Of 80 consecutive patients referred for neurophysiological evaluations of proximal lower limb weakness, 32 fulfilled strict inclusion criteria and had adequate information, including estimates of ax...

journal_title：Muscle & nerve

authors： Kuntzer T,van Melle G,Regli F

更新日期：1997-02-01 00:00:00

abstract：:Spastic paresis follows chronic disruption of the central execution of volitional command. Motor function in patients with spastic paresis is subjected over time to three fundamental insults, of which the last two are avoidable: (1) the neural insult itself, which causes paresis, i.e., reduced voluntary motor unit rec...

journal_title：Muscle & nerve

authors： Gracies JM

更新日期：2005-05-01 00:00:00

abstract：:During postnatal development of extensor digitorum longus (EDL) muscle, sodium withdrawal contractures were observed during the first 6 days after birth, and not after this time. In regenerating EDL muscles, zero-Na contractures were demonstrated: (1) 7 days after bupivacaine injection, but not 14 or 90 days after thi...

journal_title：Muscle & nerve

authors： Louboutin JP,Noireaud J

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:In adult males, cross-sectional area (CSA) for type II muscle fibers is generally larger than for type I fibers. In this cross-sectional study the aim was to compare sex-related CSAs of various muscle fiber types during childhood-to-adulthood transition. METHODS:Percutaneous biopsy samples were obtained fro...

journal_title：Muscle & nerve

authors： Esbjörnsson ME,Dahlström MS,Gierup JW,Jansson EC

更新日期：2020-12-21 00:00:00

abstract：:We have devised a method of sensory nerve conduction in the interdigital nerves of the foot using the near-nerve needle and signal averaging techniques. In 40 normal controls between the ages of 20 and 59, there was no difficulty in recording sensory compound nerve action potential (CNAP) in the various interdigital n...

journal_title：Muscle & nerve

authors： Oh SJ,Kim HS,Ahmad BK

更新日期：1984-03-01 00:00:00

abstract：:Myophosphorylase deficiency (McArdle's disease) may present with episodic renal failure following exertion. We present a case of adult-onset myophosphorylase deficiency in which recurrent bouts of renal failure could not be associated with any exertional events until a tonic seizure was witnessed after the fourth epis...

journal_title：Muscle & nerve

authors： Walker AR,Tschetter K,Matsuo F,Flanigan KM

更新日期：2003-11-01 00:00:00

abstract：:Cerebral palsy (CP) is the most prevalent neurologic disease in children and a leading cause of severe physical disability. Research and clinical experience indicate that children with CP have abnormal neuromuscular junctions (NMJs), and we present evidence that nonapposition of neuromuscular junction components is as...

journal_title：Muscle & nerve

authors： Theroux MC,Oberman KG,Lahaye J,Boyce BA,Duhadaway D,Miller F,Akins RE

更新日期：2005-11-01 00:00:00

abstract：:This longitudinal study of 194 patients with sporadic ALS demonstrated that it is possible for physicians to predict the approximate survival time for an individual ALS patient given: (1) the age of the patient, (2) the duration of his weakness and (3) an estimate of his clinical disability (ALS Score). This informati...

journal_title：Muscle & nerve

authors： Jablecki CK,Berry C,Leach J

更新日期：1989-10-01 00:00:00

abstract：INTRODUCTION:We describe the ultrasonographic findings of sciatic nerve endometriosis. METHODS:Two premenopausal women with catamenial sciatica symptoms were examined, the first without a history of endometriosis, the second with previously confirmed endometriosis of the ovary. Ultrasonography, extending from the scia...

journal_title：Muscle & nerve

authors： Arányi Z,Polyák I,Tóth N,Vermes G,Göcsei Z

更新日期：2016-09-01 00:00:00

abstract：:When an active muscle is stretched, the force increases due to strain of contractile and noncontractile proteins. We examined this force enhancement in rat extensor digitorum longus (EDL) and soleus muscles, which differ in their composition of these proteins, and their susceptibility to damage. Small stretches were a...

journal_title：Muscle & nerve

authors： Ramsey KA,Bakker AJ,Pinniger GJ

更新日期：2010-11-01 00:00:00

abstract：:The reliability of motor unit number estimation (MUNE) for assessment of the long-term course of ALS is dependent on the reproducibility of the technique. We report our results with the statistical method of MUNE on the ulnar nerve/hypothenar muscle in 16 ALS patients who were studied on 52 occasions. On each occasion...

journal_title：Muscle & nerve

authors： Olney RK,Yuen EC,Engstrom JW

更新日期：2000-02-01 00:00:00

abstract：:Rhabdomyolysis, a syndrome of skeletal muscle breakdown with leakage of muscle contents, is frequently accompanied by myoglobinuria, and if sufficiently severe, acute renal failure with potentially life-threatening metabolic derangements may ensue. A diverse spectrum of inherited and acquired disorders affecting muscl...

journal_title：Muscle & nerve

authors： Warren JD,Blumbergs PC,Thompson PD

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:In this study, we questioned whether local cooling of muscle or heating involving core and muscle temperatures are the main indicators for force variability. METHODS:Ten volunteers performed a 2-min maximum voluntary contraction (MVC) of the knee extensors under control (CON) conditions after passive heat...

journal_title：Muscle & nerve

authors： Brazaitis M,Skurvydas A,Pukėnas K,Daniuseviciūtė L,Mickevicienė D,Solianik R

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:We aimed at evaluating the differential involvement of large myelinated Aβ-, small myelinated Aδ-, and unmyelinated C-fibers in patients with diabetic polyneuropathy and how they contribute to neuropathic pain. METHODS:We collected clinical and diagnostic test variables in 133 consecutive patients with diab...

journal_title：Muscle & nerve

authors： Galosi E,Di Pietro G,La Cesa S,Di Stefano G,Leone C,Fasolino A,Di Lionardo A,Leonetti F,Buzzetti R,Mollica C,Cruccu G,Truini A

更新日期：2021-01-01 00:00:00

abstract：:To clarify the molecular nature of the pathogenesis in X-linked Emery-Dreifuss muscular dystrophy (EDMD), we monitored the expression of 2400 genes in control and EDMD fibroblasts by using complementary DNA (cDNA) microarray techniques. A total of 60 genes whose expression was altered in EDMD fibroblasts when compared...

journal_title：Muscle & nerve

authors： Tsukahara T,Tsujino S,Arahata K

更新日期：2002-06-01 00:00:00

abstract：:We developed electrophysiologic methods for testing the three major forelimb nerves as a tool to evaluate motor and sensory recovery in rats. Median, ulnar, or radial nerves were transected and repaired in Sprague-Dawley rats. Compound muscle action potentials (CMAPs) and somatosensory evoked potentials (SSEPs) were r...

journal_title：Muscle & nerve

authors： Wang H,Sorenson EJ,Spinner RJ,Windebank AJ

更新日期：2008-10-01 00:00:00

abstract：:The superficial peroneal nerve subserves sensation on the entire surface of the dorsum of the foot, except in small areas. All previously reported techniques for evaluating nerve conduction along this nerve tested a proximal portion of the nerve. We report a new method for evaluating sensory nerve conduction of the fo...

journal_title：Muscle & nerve

authors： Oh SJ,Demirci M,Dajani B,Melo AC,Claussen GC

更新日期：2001-05-01 00:00:00

abstract：:Diseases involving chronic inflammation can lead to prolonged exposure of skeletal muscle to inflammatory cytokines such as tumor necrosis factor alpha (TNFalpha), which may contribute to the skeletal muscle weakness seen in these conditions. In this study we examined the effect of a prolonged exposure to TNFalpha on ...

journal_title：Muscle & nerve

authors： van Kann LN,Bakker AJ

更新日期：2007-02-01 00:00:00

abstract：:Motor unit action potentials (MUAPs) evoked by repetitive, low-intensity transcranial magnetic stimulation can be modeled as a Poisson process. A mathematical consequence of such a model is that the ratio of the variance to the mean of the amplitudes of motor evoked potentials (MEPs) should provide an estimate of the ...

journal_title：Muscle & nerve

authors： Kaelin-Lang A,Conforto AB,Z'Graggen W,Hess CW

更新日期：2010-11-01 00:00:00

abstract：:Action potentials of rabbit masseter motor units (n = 42) were registered at different jaw angles to examine whether the shape of the action potential is related to length of muscle fibers in motor units and depends on the intramuscular location of the motor unit. Twitches were elicited by stimulating motoneurons in t...

journal_title：Muscle & nerve

authors： Turkawski SJ,van Eijden TM

更新日期：2001-11-01 00:00:00

abstract：:Acetylcholine receptor (AChR) metabolism was studied in muscle from juvenile and adult dogs with congenital myasthenia gravis (CMG) and their unaffected littermates. Although the amount of AChR in the junctional region of innervated CMG muscle fibers was 25% of normal, or less, denervation of CMG fibers resulted in th...

journal_title：Muscle & nerve

authors： Oda K,Lennon VA,Lambert EH,Palmer AC

更新日期：1984-11-01 00:00:00