Poisson distribution to analyze near-threshold motor evoked potentials.

abstract：:Mutations in the myelin protein zero gene (MPZ) are associated with certain demyelinating neuropathies, and in particular with Charcot-Marie-Tooth disease type 1B (CMT1B), Dejerine-Sottas syndrome, and congenital hypomyelination. MPZ mutations affecting the protein's transmembrane domain are generally associated with ...

journal_title：Muscle & nerve

authors： Eggers SD,Keswani SC,Melli G,Cornblath DR

更新日期：2004-06-01 00:00:00

abstract：:Seventy-five consecutive patients with clinical symptoms and signs of meralgia paresthetica underwent bilateral somatosensory evoked potential (SEP) studies involving stimulation of skin areas innervated by the lateral and anterior femoral cutaneous nerves of the thighs. The most common abnormality was an absolute lat...

journal_title：Muscle & nerve

authors： Cordato DJ,Yiannikas C,Stroud J,Halpern JP,Schwartz RS,Akbunar M,Cook M

更新日期：2004-01-01 00:00:00

abstract：:Calpains are Ca2+ -dependent cytosolic cysteine proteases that participate in the pathology of Duchenne muscular dystrophy (DMD). Utrophin is a functional homolog of dystrophin that partially compensates for dystrophin deficiency in myofibers of mdx mice. In this study, we investigated the susceptibility of utrophin t...

journal_title：Muscle & nerve

authors： Courdier-Fruh I,Briguet A

更新日期：2006-06-01 00:00:00

abstract：:There is a suprasegmental influence on the masseter reflex (MassR) in animals, which is mediated via the fifth nerve spinal nucleus (5SpN). Corresponding data in humans are lacking. Out of 268 prospectively recruited patients with clinical signs of acute brainstem infarctions, we identified 38 with magnetic resonance ...

journal_title：Muscle & nerve

authors： Thömke F,Marx JJ,Cruccu G,Stoeter P,Hopf HC

更新日期：2007-10-01 00:00:00

abstract：:Of 185 patients with myopathy, 22 showed abnormal muscle mitochondria. In 12 of the 22 patients, all of whom had ocular myopathy or the ophthalmoplegia-plus syndrome, muscle biopsies contained 5%-25% "ragged red" fibers. In 4 patients with a facioscapulohumeral distribution of weakness, ragged red fibers were less num...

journal_title：Muscle & nerve

authors： Kamieniecka Z,Schmalbruch H

更新日期：1978-09-01 00:00:00

abstract：INTRODUCTION:Voltage-gated Kv1 potassium channel complex (VGKC) autoantibodies subtyped for leucine-rich glioma-inactivated 1 (LGI1), contactin-associated-proteinlike 2 (CASPR2), and Kv IgGs have a spectrum of neurological presentations. Painful polyneuropathy is seen in some patients, but nerve pathology descriptions ...

journal_title：Muscle & nerve

authors： Lahoria R,Pittock SJ,Gadoth A,Engelstad JK,Lennon VA,Klein CJ

更新日期：2017-04-01 00:00:00

abstract：:To determine which sensory nerve conduction studies (S-NCS) are helpful in detecting supraclavicular axon loss brachial plexopathies, we selected 53 cases (of 417 reviewed) in whom complicating factors were absent and which, by needle electrode examination findings, involved only a single "truncal" element (upper, mid...

journal_title：Muscle & nerve

authors： Ferrante MA,Wilbourn AJ

更新日期：1995-08-01 00:00:00

abstract：INTRODUCTION:Two previously reported Norwegian patients with painful muscle cramps and giant myotonic discharges were genotyped and compared with those of members of 21 families harboring the same mutation. METHODS:Using primers specific for SCN4A and CLCN1, the DNA of the Norwegian family members was amplified and bi...

journal_title：Muscle & nerve

authors： Torbergsen T,Jurkat-Rott K,Stålberg EV,Løseth S,Hødneø A,Lehmann-Horn F

更新日期：2015-10-01 00:00:00

abstract：INTRODUCTION:This study compares the acute and chronic response of high-load resistance training (HL) to low-load resistance training with low blood flow restriction (LL-BFR) pressure. METHODS:Participants completed elbow flexion with either HL or LL-BFR or nonexercise. In the chronic study, participants in the HL and...

journal_title：Muscle & nerve

authors： Kim D,Loenneke JP,Ye X,Bemben DA,Beck TW,Larson RD,Bemben MG

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) is a degenerative disease of skeletal, respiratory, and cardiac muscles caused by defects in the dystrophin gene. More recently, brain involvement has been verified. Mitochondrial dysfunction and oxidative stress may underlie the pathophysiology of DMD. In this study we ev...

journal_title：Muscle & nerve

authors： Comim CM,Hoepers A,Ventura L,Freiberger V,Dominguini D,Mina F,Mendonça BP,Scaini G,Vainzof M,Streck EL,Quevedo J

更新日期：2016-01-01 00:00:00

abstract：:Focal entrapment of the ulnar nerve occurs most frequently in the region of the elbow, at the ulnar groove or beneath the humeroulnar aponeurosis. Surgical treatment commonly involves transposition of the nerve anterior to the medial epicondyle, in the antecubital fossa. Symptoms may recur after surgery, and, to asses...

journal_title：Muscle & nerve

authors： Matei CI,Logigian EL,Shefner JM

更新日期：2004-10-01 00:00:00

abstract：:Although the molecular defect causing Becker muscular dystrophy (BMD) has been identified, the biochemical mechanisms that lead to muscle necrosis remain unclear. Exercise-related muscle metabolism in 9 mildly affected BMD patients was assessed by muscle 31-phosphorus magnetic resonance spectroscopy ((31)P MRS) during...

journal_title：Muscle & nerve

authors： Tosetti M,Linsalata S,Battini R,Volpi L,Cini C,Presciutti O,Muntoni F,Cioni G,Siciliano G

更新日期：2011-11-01 00:00:00

abstract：:We used Southern blot analysis and the polymerase chain reaction to analyze the tissue distribution of multiple mitochondrial DNA (mtDNA) deletions in a 45-year-old man with familial mitochondrial myopathy-Southern blots showed two major types of abnormal mtDNA with approximately 4- and 8-kilobase deletions in the ske...

journal_title：Muscle & nerve

authors： Kawashima S,Ohta S,Kagawa Y,Yoshida M,Nishizawa M

更新日期：1994-07-01 00:00:00

abstract：:Loss of skeletal muscle mass (sarcopenia) is a major contributor to disability in old age. We used two-dimensional gel electrophoresis and mass spectrometry to screen for changes in proteins, and cDNA profiling to assess transcriptional regulations in the gastrocnemius muscle of adult (4 months) and aged (30 months) m...

journal_title：Muscle & nerve

authors： Altun M,Edström E,Spooner E,Flores-Moralez A,Bergman E,Tollet-Egnell P,Norstedt G,Kessler BM,Ulfhake B

更新日期：2007-08-01 00:00:00

abstract：:Multifocal motor neuropathy (MMN) is a chronic, immune-mediate, peripheral myelinopathy. Inherent in its name, MMN implies involvement of two or more motor nerves. We report three patients with weakness and partial motor conduction block restricted to a single nerve and localized to sites that are not at risk for entr...

journal_title：Muscle & nerve

authors： Felice KJ,Goldstein JM

更新日期：2002-05-01 00:00:00

abstract：INTRODUCTION:We sought to compare median nerve elasticity between leprosy patients (LPs) and healthy volunteers (HVs) using ultrasound elastography (UE). METHODS:Two radiologists independently measured the strain ratio of the median nerve/flexor digitorum superficialis muscle (MN/FDSM) of 18 LP and 18 HV using real-ti...

journal_title：Muscle & nerve

authors： Nogueira-Barbosa MH,Lugão HB,Gregio-Júnior E,Crema MD,Kobayashi MTT,Frade MAC,Pavan TZ,Carneiro AAO

更新日期：2017-09-01 00:00:00

abstract：:High-dose immunoglobulins for intravenous administration (IVIg) have originally been developed for substitution therapy in hypogammaglobulinemia. Over the last decade they are increasingly used in the treatment of immune-mediated diseases. In this review the results in immune-mediated neuromuscular diseases are summar...

journal_title：Muscle & nerve

authors： van der Meché FG,van Doorn PA

更新日期：1997-02-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) pandemic has resulted in the reorganization of health-care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies. The magnitude of the impact of this public health emergency on the...

journal_title：Muscle & nerve

authors： Veerapandiyan A,Wagner KR,Apkon S,McDonald CM,Mathews KD,Parsons JA,Wong BL,Eichinger K,Shieh PB,Butterfield RJ,Rao VK,Smith EC,Proud CM,Connolly AM,Ciafaloni E

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Posttraumatic elbow contracture is clinically challenging because injury often disrupts multiple periarticular soft tissues. Tissue specific contribution to contracture, particularly muscle, remains poorly understood. METHODS:In this study we used a previously developed animal model of elbow contracture. ...

journal_title：Muscle & nerve

authors： Dunham CL,Chamberlain AM,Meyer GA,Lake SP

更新日期：2018-12-01 00:00:00

abstract：:Case reports and open-label studies suggest that coenzyme Q(10) (CoQ(10)) treatment may have beneficial effects in mitochondrial disease patients; however, controlled trials are warranted to clinically prove its effectiveness. Thirty patients with mitochondrial cytopathy received 1200 mg/day CoQ(10) for 60 days in a r...

journal_title：Muscle & nerve

authors： Glover EI,Martin J,Maher A,Thornhill RE,Moran GR,Tarnopolsky MA

更新日期：2010-11-01 00:00:00

abstract：:Since peripheral nerve has a large ischemic safety factor, hypothermia, by reducing metabolic demands, is potentially an efficacious technique to rescue nerve from ischemic fiber degeneration (IFD). We therefore evaluated the influence of temperature on the severity of IFD resulting from a standard ischemic stress. Is...

journal_title：Muscle & nerve

authors： Kihara M,Schmelzer JD,Kihara Y,Smithson IL,Low PA

更新日期：1996-02-01 00:00:00

abstract：:The majority of patients with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes) have an A-->G mutation at nucleotide 3243 in mitochondrial transfer (t)RNA. To date there have only been 10 reported cases of MELAS syndrome in patients with a T-->C mutation at position 3271...

journal_title：Muscle & nerve

authors： Tarnopolsky MA,Maguire J,Myint T,Applegarth D,Robinson BH

更新日期：1998-01-01 00:00:00

abstract：INTRODUCTION:Evaluation of phrenic neuropathy (PN) with phrenic nerve conduction studies (PNCS) is associated with false negatives. Visualization of diaphragmatic muscle twitch with diaphragm ultrasound (DUS) when performing PNCS may help to solve this problem. METHODS:We performed bilateral, simultaneous DUS-PNCS in ...

journal_title：Muscle & nerve

authors： Johnson NE,Utz M,Patrick E,Rheinwald N,Downs M,Dilek N,Dogra V,Logigian EL

更新日期：2014-05-01 00:00:00

abstract：:An electrophysiologic study of peripheral nerve excitability was performed in patients with hyperkalemic periodic paralysis (HPP) and in normal controls. It was found that a marked degree of neural hyperexcitability existed in all patients with HPP who showed cold sensitivity. The results suggest involvement of the ne...

journal_title：Muscle & nerve

authors： Segura RP,Petajan JH

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Anti-cytosolic 5'-nucleotidase 1A (cN1A) antibodies are commonly detected in patients with sporadic inclusion body myositis (sIBM). However, their pathogenic role has not been established. Moreover, efforts toward identifying sIBM distinct clinicopathologic characteristics associated with these antibodies ha...

journal_title：Muscle & nerve

authors： Paul P,Liewluck T,Ernste FC,Mandrekar J,Milone M

更新日期：2020-12-29 00:00:00

abstract：INTRODUCTION:We evaluated diagnostic value of sensory tests during recovery from iatrogenic sensory neuropathy using intraoperatively verified nerve injury with subjective symptoms as gold standard. METHODS:Inferior alveolar nerves were monitored neurophysiologically throughout mandibular osteotomy in 19 patients. Sen...

journal_title：Muscle & nerve

authors： Teerijoki-Oksa T,Forssell H,Jääskeläinen SK

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:The neuropathy in patients with neurofibromatosis type 2 (NF2) is difficult to quantify and follow up. In this study we compared 3 methods that may help assess motor axon pathology in NF2 patients. METHODS:Nerve conduction studies in median nerves were supplemented by deriving motor unit number estimates ...

journal_title：Muscle & nerve

authors： Farschtschi S,Gelderblom M,Buschbaum S,Bostock H,Grafe P,Mautner VF

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:The ability to individualize recommendations or expectations of disease progression based on a patient's unique characteristics has merit for use in sporadic inclusion body myositis (sIBM). METHODS:Fifty-five subjects with sIBM completed a battery of strength and functional outcomes at 2 study visits. The...

journal_title：Muscle & nerve

authors： Alfano LN,Yin H,Dvorchik I,Maus EG,Flanigan KM,Mendell JR,Lowes LP

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:Skin-derived precursor cells (SKPs) are neural crest progenitor cells that can attain a Schwann cell-like phenotype through in vitro techniques (SKP-SCs). We hypothesized that SKP-SCs could produce mature myelin and, in doing so, facilitate the recovery of a focal demyelination injury. METHODS:We unilater...

journal_title：Muscle & nerve

authors： Grochmal J,Dhaliwal S,Stys PK,van Minnen J,Midha R

更新日期：2014-08-01 00:00:00

abstract：INTRODUCTION:Few data are available to quantify the risks and benefits of microvascular decompression (MVD) in elderly patients with hemifacial spasm. METHODS:Twenty-seven patients >65 years of age and 104 younger patients who underwent MVD for hemifacial spasm (HFS) over a 3-year period were analyzed retrospectively ...

journal_title：Muscle & nerve

authors： Sekula RF Jr,Frederickson AM,Arnone GD,Quigley MR,Hallett M

更新日期：2013-11-01 00:00:00