Anti-cN1A antibodies do not correlate with specific clinical, electromyographic, or pathological findings in sporadic inclusion body myositis.

abstract：:Ultrasound (US) technique was applied to measure the thickness, cross-sectional area (CSA), and internal structure of the quadriceps muscle in 70- to 80-year-old endurance and power athletes and untrained men. Isometric knee extension strength was higher in the power athletes than in the other groups. The mean values ...

journal_title：Muscle & nerve

authors： Sipilä S,Suominen H

更新日期：1991-06-01 00:00:00

abstract：:The purpose of this study was to determine if chronic fatigue syndrome (CSF) is characterized by abnormalities in oxidative muscle metabolism. Patients with CFS according to Centers for Disease Control (CDC) criteria (n = 22) were compared to normal sedentary subjects (n = 15). CFS patients were also tested before and...

journal_title：Muscle & nerve

authors： McCully KK,Natelson BH,Iotti S,Sisto S,Leigh JS Jr

更新日期：1996-05-01 00:00:00

abstract：:Phospholipid methylation is thought to modulate such vital cellular processes as calcium transport, receptor function, and membrane microviscosity. As these processes are fundamental to the function of muscle cells and are thought to be altered in disease states, we have characterized several features of phospholipid ...

journal_title：Muscle & nerve

authors： Kuncl RW,Drachman DB,Kishimoto Y

更新日期：1985-06-01 00:00:00

abstract：:A small-scale procedure for preparing tightly coupled intact skeletal muscle mitochondria from myodystrophic (myd/myd) mice is described. Mitochondrial preparations derived from heart, liver, and skeletal muscle of myd/myd and their littermate (+/?) controls are characterized with respect to their cytochrome content a...

journal_title：Muscle & nerve

authors： Lee CP,Martens ME,Jankulovska L,Neymark MA

更新日期：1979-09-01 00:00:00

abstract：:The muscle-specific helix-loop-helix (HLH) transcription factors myoD, myogenin, MRF4, and myf-5 are called the muscle regulatory factor family (MRF). Levels of MRFs are strongly regulated by muscle electrical activity and are thought to control downstream genes that are important for muscle phenotype such as the acet...

journal_title：Muscle & nerve

authors： Carlsen H,Gundersen K

更新日期：2000-09-01 00:00:00

abstract：INTRODUCTION:Posttraumatic elbow contracture is clinically challenging because injury often disrupts multiple periarticular soft tissues. Tissue specific contribution to contracture, particularly muscle, remains poorly understood. METHODS:In this study we used a previously developed animal model of elbow contracture. ...

journal_title：Muscle & nerve

authors： Dunham CL,Chamberlain AM,Meyer GA,Lake SP

更新日期：2018-12-01 00:00:00

abstract：:The F-wave was used to estimate the fastest motor nerve conduction velocity (MNCV) along the proximal segment (spinal cord to knee) of the axons of the tibial nerve in 65 control subjects, 8 patients with diabetic polyneuropathy, and 4 patients with Charcot-Marie-Tooth disease. Terminal latencies and MNCV along the di...

journal_title：Muscle & nerve

authors： Panayiotopoulos CP,Scarpalezos S,Nastas PE

更新日期：1978-05-01 00:00:00

abstract：INTRODUCTION:Despite the existence of guidelines, painful neuropathy is often inappropriately treated. We sought to determine the effectiveness of a clinical decision support system on guideline-recommended medication use. METHODS:We randomized neurology providers, stratified by subspecialty, to a best practice alert ...

journal_title：Muscle & nerve

authors： Reynolds EL,Burke JF,Banerjee M,Callaghan BC

更新日期：2020-05-01 00:00:00

abstract：:Muscle fatigue or neuromuscular disease may result in central activation failure during maximal voluntary contractions (MVCs). Superimposition of an electrically stimulated contraction during an MVC has been used to detect central activation failure. To determine the most sensitive means of quantitating central activa...

journal_title：Muscle & nerve

authors： Kent-Braun JA,Le Blanc R

更新日期：1996-07-01 00:00:00

abstract：INTRODUCTION:Detection of denervation in muscles in the craniobulbar area is important to assure widespread lower motor neuron involvement in the diagnosis of amyotrophic lateral sclerosis (ALS). The value of spontaneous activity analysis in needle electromyography (EMG) of the tongue has been questioned in the recent ...

journal_title：Muscle & nerve

authors： Tankisi H,Otto M,Pugdahl K,Fuglsang-Frederiksen A

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:The radial nerve and posterior interosseous nerve (PIN) are prone to injury at multiple sites. Electrodiagnostic (EDx) studies may only identify the most proximal lesion. Nerve ultrasound could augment EDx by visualizing additional pathology. METHODS:This investigation was a retrospective examination of u...

journal_title：Muscle & nerve

authors： Dietz AR,Bucelli RC,Pestronk A,Zaidman CM

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:Myelinating Schwann cells compartmentalize their outermost layer to form actin-rich channels known as Cajal bands. Herein we investigate changes in Schwann cell architecture and cytoplasmic morphology in a novel mouse model of carpal tunnel syndrome. METHODS:Chronic nerve compression (CNC) injury was crea...

journal_title：Muscle & nerve

authors： Gupta R,Nassiri N,Hazel A,Bathen M,Mozaffar T

更新日期：2012-02-01 00:00:00

abstract：:Electrophysiologic findings in thallium intoxication are usually untimely, limited in extent, and often uninformative. This report documents serial conduction and electromyographic findings in a case of thallium poisoning, beginning 10 days after symptom onset and ending 24 months later. Initially, the plantar nerves ...

journal_title：Muscle & nerve

authors： Dumitru D,Kalantri A

更新日期：1990-05-01 00:00:00

abstract：:Mutations of the valosin-containing protein gene (VCP) are responsible for autosomal-dominant hereditary inclusion-body myopathy associated with frontotemporal dementia and Paget's disease of bone. We identified the p.R155C missense mutation in the VCP gene segregating in an Italian family with three affected siblings...

journal_title：Muscle & nerve

authors： Gidaro T,Modoni A,Sabatelli M,Tasca G,Broccolini A,Mirabella M

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:While current exercise guidelines recommend progressive, high-intensity resistance training (RT) to promote muscle hypertrophy and strength gains, controversy exists regarding the efficacy of lighter-load RT. We compared 2 work-matched RT interventions that differed in training intensity. METHODS:Fifteen ...

journal_title：Muscle & nerve

authors： Alegre LM,Aguado X,Rojas-Martín D,Martín-García M,Ara I,Csapo R

更新日期：2015-01-01 00:00:00

abstract：:A patient in perfect health prior to electrical shock developed an ALS-like syndrome after the shock. Onset of the disease occurred in the limb through which the shock entered, and subsequently followed a course well-described in previous case reports. Possible mechanisms of disease are discussed. ...

journal_title：Muscle & nerve

authors： Sirdofsky MD,Hawley RJ,Manz H

更新日期：1991-10-01 00:00:00

abstract：:To delineate change in median nerve size in carpal tunnel syndrome (CTS), we compared ultrasonograms of nerve cross-sections from patients (201 wrists of 125 women with idiopathic CTS) and controls (200 dominant wrists of 200 women). Major and minor axes, cross-sectional area, and the flattening ratio (major axis/mino...

journal_title：Muscle & nerve

authors： Nakamichi KI,Tachibana S

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The goals of this study were to determine whether serum concentrations of endocannabinoids (eCB) and related lipids predict disease status in patients with amyotrophic lateral sclerosis (ALS) relative to healthy controls, and whether concentrations correlate with disease duration and severity. METHODS:Serum...

journal_title：Muscle & nerve

authors： Carter GT,McLaughlin RJ,Cuttler C,Sauber GJ,Weeks DL,Hillard CJ,Weiss MD

更新日期：2021-01-01 00:00:00

abstract：:Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basemen...

journal_title：Muscle & nerve

authors： Duance VC,Black CM,Dubowitz V,Hughes GR,Bailey AJ

更新日期：1980-11-01 00:00:00

abstract：:A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...

journal_title：Muscle & nerve

authors： Krishnamurthy KB,Liu GT,Logigian EL

更新日期：1993-11-01 00:00:00

abstract：INTRODUCTION:In this study, we analyzed the crosstalk in mechanomyographic (MMG) signals generated by the extensor digitorum (ED), extensor carpi ulnaris (ECU), and flexor carpi ulnaris (FCU) muscles of the forearm during wrist flexion (WF) and extension (WE) and radial (RD) and ulnar (UD) deviations. METHODS:Twenty r...

journal_title：Muscle & nerve

authors： Islam A,Sundaraj K,Ahmad RB,Sundaraj S,Ahamed NU,Ali MA

更新日期：2015-06-01 00:00:00

abstract：:Peripheral nerve lesions are sometimes associated with focal dystonia. We diagnosed ulnar neuropathy in 28 of 73 (40%) cases of occupational cramp in musicians. Focal slowing of ulnar conduction across the elbow was identified in 15 of 19 (79%) patients using the near nerve technique and in 5 of 17 (29%) patients usin...

journal_title：Muscle & nerve

authors： Charness ME,Ross MH,Shefner JM

更新日期：1996-04-01 00:00:00

abstract：:Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal dominant disorder characterized by recurrent mononeuropathies or brachial plexopathies, commonly associated with a chromosome 17p11.2-12 deletion encompassing the peripheral myelin protein-22 (PMP22) gene. We tried to identify criteria dis...

journal_title：Muscle & nerve

authors： Pareyson D,Solari A,Taroni F,Botti S,Fallica E,Scaioli V,Ciano C,Sghirlanzoni A

更新日期：1998-12-01 00:00:00

abstract：:Statins can induce necrotizing or inflammatory myopathies in some patients. Increased major histocompatibility complex class I (MHC I) expression has been shown in muscle biopsies of statin-induced myopathy. Therefore, we investigated the effect of statins on the expression of MHC I in muscle cells. Using flow cytomet...

journal_title：Muscle & nerve

authors： Singh P,Kohr D,Kaps M,Blaes F

更新日期：2010-02-01 00:00:00

abstract：:Twenty-four adult albino rats were injected with tetanus toxin into the right gastrocnemius muscle and then subjected to sustained dorsiflexion of the right ankle joint for 2 to 14 days. Histologic examinations of the soleus after this procedure showed myopathic changes, characterized by variations in fiber diameters,...

journal_title：Muscle & nerve

authors： Mizuno Y,Chou SM

更新日期：1990-10-01 00:00:00

abstract：INTRODUCTION:A randomized trial demonstrated benefit from thymectomy in nonthymomatous acetylcholine receptor (AChR)-antibody positive myasthenia gravis (MG). Uncontrolled observational and histologic studies suggest thymectomy may not be efficacious in anti-muscle-specific kinase (MuSK)-MG. METHODS:The therapeutic im...

journal_title：Muscle & nerve

authors： Clifford KM,Hobson-Webb LD,Benatar M,Burns TM,Barnett C,Silvestri NJ,Howard JF Jr,Visser A,Crum BA,Nowak R,Beekman R,Kumar A,Ruzhansky K,Chen IA,Pulley MT,Laboy SM,Fellman MA,Howard DB,Kolb NA,Greene SM,Pasnoor M

更新日期：2019-04-01 00:00:00

abstract：:The present study was conducted to determine the effects of acute overload exercise on mitochondrial DNA and the structure of skeletal muscles. Rats were forced to run for 20 min until reaching complete exhaustion. We detected the large-scale deletion (7052 bp) of mitochondrial DNA by the nested polymerase chain react...

journal_title：Muscle & nerve

authors： Sakai Y,Iwamura Y,Hayashi J,Yamamoto N,Ohkoshi N,Nagata H

更新日期：1999-02-01 00:00:00

abstract：:As applied to skeletal muscle, stem cell therapy is a reincarnation of myoblast transfer therapy that has resulted from recent advances in the cell biology of skeletal muscle. Both strategies envisage the reconstruction of damaged muscle from its precursors, but stem cell therapy employs precursors that are earlier in...

journal_title：Muscle & nerve

authors： Partridge TA

更新日期：2003-02-01 00:00:00

abstract：:The diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) relies primarily on clinical and electrophysiologic examination, but the nerve biopsy findings may be supportive, especially in atypical cases. In order to define the usefulness of nerve biopsy in this disease, we retrospectively studied 44 cons...

journal_title：Muscle & nerve

authors： Vallat JM,Tabaraud F,Magy L,Torny F,Bernet-Bernady P,Macian F,Couratier P

更新日期：2003-04-01 00:00:00

abstract：:The neuromuscular junction (NMJ) is a complex structure that serves to efficiently communicate the electrical impulse from the motor neuron to the skeletal muscle to signal contraction. Over the last 200 years, technological advances in microscopy allowed visualization of the existence of a gap between the motor neuro...

journal_title：Muscle & nerve

authors： Hughes BW,Kusner LL,Kaminski HJ

更新日期：2006-04-01 00:00:00