Spontaneous electromyographic activity of the tongue in amyotrophic lateral sclerosis.

abstract：:To investigate whether various myelin markers could detect pathological changes in myelination, the activity of 2'-3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and the level of PO protein were compared in the peripheral nervous system (PNS) of the dystrophic mouse and chicken and their phenotypically normal sibling...

journal_title：Muscle & nerve

authors： Lewis LN,Mezei C

更新日期：1985-02-01 00:00:00

abstract：:In an attempt to determine the relative importance of the nerve cell body and of the axon in initiating and controlling axonal regeneration, nerve cell bodies were irradiated and the ability of the distal axon to sprout was examined. Mice were subjected to either 25 or 50 Gray (Gy) of x-irradiation localized to the lu...

journal_title：Muscle & nerve

authors： Pamphlett RS

更新日期：1988-05-01 00:00:00

abstract：:To obtain normative muscle morphology data on a healthy population recruited from a population survey, we examined vastus lateralis biopsies from 58 men and 33 women, aged 26-67 years. Biopsies were measured with automated, computer-aided techniques. Data were analyzed according to gender and age, and the influence of...

journal_title：Muscle & nerve

authors： Toft I,Lindal S,Bønaa KH,Jenssen T

更新日期：2003-07-01 00:00:00

abstract：:Neuromyotonia or Isaacs' syndrome is a rare peripheral nerve hyperexcitability disorder caused by antibodies against potassium channels of myelinated axons. We present the high-density surface electromyographic (EMG) recordings of a patient with fasciculations and cramps due to neuromyotonia. To characterize the time ...

journal_title：Muscle & nerve

authors： Kleine BU,Stegeman DF,Drost G,Zwarts MJ

更新日期：2008-02-01 00:00:00

abstract：:The mutual links between muscle pain and resting electromyographic (EMG) activity are still controversial. This study described effects of experimental muscle pain on resting EMG activity in a jaw-closing muscle and a leg muscle. Pain was induced by injections of hypertonic saline into the muscles in 10 subjects. Inje...

journal_title：Muscle & nerve

authors： Svensson P,Graven-Nielsen T,Matre D,Arendt-Nielsen L

更新日期：1998-11-01 00:00:00

abstract：:On magnetic resonance (MR) imaging of the brachial plexus increased signal intensity and swelling of the brachial plexus has been found in chronic inflammatory demyelinating polyneuropathy (CIDP). Whether these proximal abnormalities are also present in the distal polyneuropathy associated with monoclonal gammopathy i...

journal_title：Muscle & nerve

authors： Eurelings M,Notermans NC,Franssen H,Van Es HW,Ramos LM,Wokke JH,van den Berg LH

更新日期：2001-10-01 00:00:00

abstract：:Five members of the same family, along three generations, presented with hypertrophic cardiomyopathy. Neurological examination, muscle strength, electromyography, and serum creatine kinase were normal. Skeletal muscle biopsy showed abnormal lipid accumulation and carnitine deficiency. In three patients the cardiac sym...

journal_title：Muscle & nerve

authors： Bautista J,Rafel E,Martinez A,Sainz I,Herrera J,Segura L,Chinchon I

更新日期：1990-03-01 00:00:00

abstract：:There were 31 Duchenne patients placed on overnight mouth intermittent positive pressure ventilation for severe respiratory insufficiency at the average age of 19.9 years. Most patients had vital capacities less than 200 cc at their last evaluations. Of these, 23 patients are alive at the average age of 27 years and l...

journal_title：Muscle & nerve

authors： Bach JR,O'Brien J,Krotenberg R,Alba AS

更新日期：1987-02-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine the patterns of responses for the electromyographic (EMG) amplitude vs. oxygen uptake ( V̇O2 ) relationships from muscles of the quadriceps femoris and hamstrings during incremental treadmill running. METHODS:Twelve men volunteered to perform an incremental test to e...

journal_title：Muscle & nerve

authors： Camic CL,Kovacs AJ,Enquist EA,McLain TA,Hill EC

更新日期：2015-12-01 00:00:00

abstract：:Reliable unipedal balance is fundamental to safe ambulation. Accordingly, older persons with peripheral neuropathy (PN), who are at increased risk for falls, demonstrate impaired unipedal balance. To explore the relationship between afferent function and unipedal balance, frontal plane proprioceptive thresholds at the...

journal_title：Muscle & nerve

authors： Son J,Ashton-Miller JA,Richardson JK

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:We sought to compare median nerve elasticity between leprosy patients (LPs) and healthy volunteers (HVs) using ultrasound elastography (UE). METHODS:Two radiologists independently measured the strain ratio of the median nerve/flexor digitorum superficialis muscle (MN/FDSM) of 18 LP and 18 HV using real-ti...

journal_title：Muscle & nerve

authors： Nogueira-Barbosa MH,Lugão HB,Gregio-Júnior E,Crema MD,Kobayashi MTT,Frade MAC,Pavan TZ,Carneiro AAO

更新日期：2017-09-01 00:00:00

abstract：:The Moberg Pick-Up Test is a standardized test for assessing hand dexterity. Although reduction of sensation in the hand occurs with aging, the effect of age on a subject's performance of the Moberg Pick-Up Test has not been examined. The primary goal of this study was to examine the impact of aging and, secondarily, ...

journal_title：Muscle & nerve

authors： Amirjani N,Ashworth NL,Gordon T,Edwards DC,Chan KM

更新日期：2007-06-01 00:00:00

abstract：:The clinical, pathologic, and genetic findings of a boy with intranuclear nemaline rod myopathy are described. Serial muscle biopsies revealed myocyte nuclei containing inclusions that were immunoreactive for alpha-actinin and increased with age. Genetic analysis revealed a Val163Leu ACTA1 mutation previously associat...

journal_title：Muscle & nerve

authors： Kaimaktchiev V,Goebel H,Laing N,Narus M,Weeks D,Nixon R

更新日期：2006-09-01 00:00:00

abstract：:To enable the quantitative assessment of peripheral nerve structure and function, we determined the normal values for sural nerve hydration structure as measured by magnetic resonance proton imaging, and for neurological function with scores for neuropathic symptoms, signs, and nerve conduction properties. Normal huma...

journal_title：Muscle & nerve

authors： Eaton RP,Sibbitt WL Jr,Bicknell JM,King MK,Griffey RH,Sibbitt RR

更新日期：1993-03-01 00:00:00

abstract：:Beta-chemokines attract and activate T cells and monocytes and have a key role in chronic inflammation. Certain beta-chemokines, such as monocyte chemoattractant protein-1 (MCP-1), have been reported to be upregulated in the idiopathic inflammatory myopathies (IIM). We studied the distribution of beta-chemokine recept...

journal_title：Muscle & nerve

authors： De Paepe B,De Bleecker JL

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Anti-cytosolic 5'-nucleotidase 1A (cN1A) antibodies are commonly detected in patients with sporadic inclusion body myositis (sIBM). However, their pathogenic role has not been established. Moreover, efforts toward identifying sIBM distinct clinicopathologic characteristics associated with these antibodies ha...

journal_title：Muscle & nerve

authors： Paul P,Liewluck T,Ernste FC,Mandrekar J,Milone M

更新日期：2020-12-29 00:00:00

abstract：INTRODUCTION:The p.A1156T mutation alters the function of the voltage-gated sodium channel Nav1.4 on the muscle sarcolemma, causing a channelopathy without overt myotonia or periodic paralysis but with myalgic pain. METHODS:A postal survey was conducted to assess the prevalence and characteristics of pain and related ...

journal_title：Muscle & nerve

authors： Suokas K,Palmio J,Sandell S,Udd B,Hietaharju A

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:In Duchenne muscular dystrophy (DMD), fat replacement of muscle may be a useful endpoint in trials of therapy, although progression in different muscle groups is uneven. In this study we assessed the progression of fat replacement with T(1) -weighted imaging over 2 9-month periods. METHODS:Eight ambulant,...

journal_title：Muscle & nerve

authors： Hollingsworth KG,Garrood P,Eagle M,Bushby K,Straub V

更新日期：2013-10-01 00:00:00

abstract：:Genetic testing is rapidly becoming an increasingly significant part of the diagnostic armamentarium of neuromuscular clinicians. Although technically easy to order, the results of such testing, whether positive or negative, have potentially enormous consequences for the individual tested and for family members. As a ...

journal_title：Muscle & nerve

authors： Su X,Kang PB,Russell JA,Simmons Z

更新日期：2016-12-01 00:00:00

abstract：:A patient with neuromyotonia, peripheral neuropathy and myasthenia gravis (MG) is described. Neurophysiological studies, at rest, showed continuous muscle discharges of motor unit action potentials (MUAPs) in duplets and triplets. Motor (MNCV) and sensory (SNCV) nerve conduction studies revealed mild axonal and demyel...

journal_title：Muscle & nerve

authors： Martinelli P,Patuelli A,Minardi C,Cau A,Riviera AM,Dal Pozzo F

更新日期：1996-04-01 00:00:00

abstract：:Influenza vaccination has been associated with adverse events including Guillain-Barré syndrome. Because the safety of influenza vaccination in patients with myasthenia gravis (MG) has not been established, some clinicians discourage vaccination for these patients. We explored whether the administration of influenza v...

journal_title：Muscle & nerve

authors： Zinman L,Thoma J,Kwong JC,Kopp A,Stukel TA,Juurlink DN

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:This study compares the acute and chronic response of high-load resistance training (HL) to low-load resistance training with low blood flow restriction (LL-BFR) pressure. METHODS:Participants completed elbow flexion with either HL or LL-BFR or nonexercise. In the chronic study, participants in the HL and...

journal_title：Muscle & nerve

authors： Kim D,Loenneke JP,Ye X,Bemben DA,Beck TW,Larson RD,Bemben MG

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:We studied neurodevelopmental and behavioral/emotional symptoms in patients with Duchenne muscular dystrophy (DMD). METHODS:Retrospective case series of neurodevelopmental and behavioral/emotional symptoms obtained through review of systems of 700 DMD patients in relation to dystrophin gene mutations. RE...

journal_title：Muscle & nerve

authors： Darmahkasih AJ,Rybalsky I,Tian C,Shellenbarger KC,Horn PS,Lambert JT,Wong BL

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Myelinating Schwann cells compartmentalize their outermost layer to form actin-rich channels known as Cajal bands. Herein we investigate changes in Schwann cell architecture and cytoplasmic morphology in a novel mouse model of carpal tunnel syndrome. METHODS:Chronic nerve compression (CNC) injury was crea...

journal_title：Muscle & nerve

authors： Gupta R,Nassiri N,Hazel A,Bathen M,Mozaffar T

更新日期：2012-02-01 00:00:00

abstract：:Normal motor units (MUs) were simulated and their architecture altered to simulate the changes produced by myopathy. The concentric needle electromyographic recordings of motor unit action potentials (MUAPs) from the MUs were then also simulated. These simulated MUAPs showed features that are seen in myopathy: normal ...

journal_title：Muscle & nerve

authors： Nandedkar SD,Sanders DB

更新日期：1989-03-01 00:00:00

abstract：:The lack of effective therapy for many of the chronic neuromuscular diseases such as amyotrophic lateral sclerosis, hereditary motor sensory neuropathy (Charcot-Marie-Tooth disease), spinocerebellar degenerations and idiopathic polyneuropathy has led to a search for substances that may stimulate peripheral nerve regen...

journal_title：Muscle & nerve

authors： Bradley WG

更新日期：1990-09-01 00:00:00

abstract：INTRODUCTION:Thymectomy is required for the treatment of thymoma-associated myasthenia gravis (MG). However, MG may develop only after thymectomy, a condition known as post-thymectomy MG. This study aimed to investigate the risk factors for post-thymectomy MG in patients with thymoma. METHODS:We retrospectively identi...

journal_title：Muscle & nerve

authors： Kim A,Choi SJ,Kang CH,Lee S,Son H,Kim JA,Shin JY,Kim SM,Hong YH,Sung JJ

更新日期：2021-01-12 00:00:00

abstract：INTRODUCTION:Muscle weakness and functional disability have not been evaluated in a population-based study of patients with myasthenia gravis (MG). METHODS:All patients with MG in a well-defined catchment area were identified in the Danish National Patient Registry. Of the 175 eligible patients, 90 participated and we...

journal_title：Muscle & nerve

authors： Vinge L,Jakobsen J,Andersen H

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Nerve enlargement (NE) is described in inflammatory and inherited neuropathies. It is commonly multifocal and moderate in the former and homogeneous and generalized in the latter. We describe 4 cases of massive NE in inflammatory neuropathies. METHODS:Patients presented with symptoms of polyneuropathy tha...

journal_title：Muscle & nerve

authors： Grimm A,Schubert V,Axer H,Ziemann U

更新日期：2017-02-01 00:00:00

abstract：:The presence of differences in motor unit activity across contraction types and between hands suggests that the magnitude of fluctuations in motor output is only weakly related when these conditions are compared. Twenty right-handed young (24.1 +/- 5.3 years) and old (72.5 +/- 4.9 years) adults performed three levels ...

journal_title：Muscle & nerve

authors： Shinohara M,Keenan KG,Enoka RM

更新日期：2005-06-01 00:00:00