Polymyositis--an immunofluorescence study on the distribution of collagen types.

Abstract:

:Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basement membrane collagens (Types IV and V) as well as the proliferation of perimysial Type III collagen are discussed in relation to the muscle atrophy observed during the disease.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Duance VC,Black CM,Dubowitz V,Hughes GR,Bailey AJ

doi

10.1002/mus.880030605

subject

Has Abstract

pub_date

1980-11-01 00:00:00

pages

487-90

issue

6

eissn

0148-639X

issn

1097-4598

journal_volume

3

pub_type

杂志文章
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