Abstract:
:A small-scale procedure for preparing tightly coupled intact skeletal muscle mitochondria from myodystrophic (myd/myd) mice is described. Mitochondrial preparations derived from heart, liver, and skeletal muscle of myd/myd and their littermate (+/?) controls are characterized with respect to their cytochrome content and their oxidative and phosphorylative capacities. Our data indicate that there is an impairment in the NADH CoQ region of the respiratory chain of myodystrophic skeletal muscle mitochondria. Both heart and liver mitochondria of myd/myd exhibited normal activities of respiratory chain-linked oxidative phosphorylation.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Lee CP,Martens ME,Jankulovska L,Neymark MAdoi
10.1002/mus.880020504subject
Has Abstractpub_date
1979-09-01 00:00:00pages
340-8issue
5eissn
0148-639Xissn
1097-4598journal_volume
2pub_type
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