An Italian family with inclusion-body myopathy and frontotemporal dementia due to mutation in the VCP gene.

abstract：:Measurements were done on the biceps muscles of 6 healthy volunteers to record simultaneously the surface electromyogram (EMG) and vibromyogram (VMG) by means of a piezoelectric device (accelerometer). The VMG is generated by mechanical waves due to the contraction mechanism and often measured as sound. The frequency ...

journal_title：Muscle & nerve

authors： Zwarts MJ,Keidel M

更新日期：1991-08-01 00:00:00

abstract：:The muscle-specific helix-loop-helix (HLH) transcription factors myoD, myogenin, MRF4, and myf-5 are called the muscle regulatory factor family (MRF). Levels of MRFs are strongly regulated by muscle electrical activity and are thought to control downstream genes that are important for muscle phenotype such as the acet...

journal_title：Muscle & nerve

authors： Carlsen H,Gundersen K

更新日期：2000-09-01 00:00:00

abstract：:Infantile botulism is a recently recognized cause of acute hypotonic paresis and respiratory failure in young infants. Electrophysiological testing has proven useful in early diagnosis in suspected cases by demonstrating abnormal neuromuscular transmission as is known to occur in botulism. Twenty-five infants with bac...

journal_title：Muscle & nerve

authors： Cornblath DR,Sladky JT,Sumner AJ

更新日期：1983-07-01 00:00:00

abstract：:A quantitative assessment was made of the firing characteristics of repetitive axonal discharges encountered during microneurographic recordings from human peripheral nerves. Spontaneous activity was recorded from 16 single axons using tungsten microelectrodes inserted percutaneously into fascicles of the median or pe...

journal_title：Muscle & nerve

authors： Macefield VG

更新日期：1998-04-01 00:00:00

abstract：:Muscle sodium-channel disorders cover a spectrum of rare myotonic diseases. In a German family with 17 affected individuals in four generations, we identified a heterozygous missense mutation in exon 24 A1481D (c.4442 C>A) of the voltage-gated sodium channel gene (SCN4A) alpha subunit. Phenotypes of 12 family members ...

journal_title：Muscle & nerve

authors： Schoser BG,Schröder JM,Grimm T,Sternberg D,Kress W

更新日期：2007-05-01 00:00:00

abstract：:Denervation induces muscle fiber atrophy and changes in the gene expression rates of skeletal muscle. Electrical stimulation (ES) is a procedure generally used to treat denervated muscles in humans. This study evaluated the effect of ES based on chronaxie and rheobase on the expression of the myoD and atrogin-1 genes ...

journal_title：Muscle & nerve

authors： Russo TL,Peviani SM,Freria CM,Gigo-Benato D,Geuna S,Salvini TF

更新日期：2007-01-01 00:00:00

abstract：:Patients (n = 41) with isolated weakness of the eyelids or extraocular muscles, who had been referred for single fiber electromyography (SFEMG), were followed up after 4 to 24 months, At follow-up the patients were classified as "definite ocular myasthenia gravis" (MG), "definite other diagnosis," or "no definite diag...

journal_title：Muscle & nerve

authors： Rouseev R,Ashby P,Basinski A,Sharpe JA

更新日期：1992-03-01 00:00:00

abstract：:Influenza vaccination has been associated with adverse events including Guillain-Barré syndrome. Because the safety of influenza vaccination in patients with myasthenia gravis (MG) has not been established, some clinicians discourage vaccination for these patients. We explored whether the administration of influenza v...

journal_title：Muscle & nerve

authors： Zinman L,Thoma J,Kwong JC,Kopp A,Stukel TA,Juurlink DN

更新日期：2009-12-01 00:00:00

abstract：:To determine the contributions of neural and mechanical mechanisms to the limits in the range of motion (ROM) about a joint, we studied the effects of 30 sessions of static stretch training on the characteristics of the plantar-flexor muscles in 12 subjects. Changes in the maximal ankle dorsiflexion and the torque pro...

journal_title：Muscle & nerve

authors： Guissard N,Duchateau J

更新日期：2004-02-01 00:00:00

abstract：:The effects of hyperbaric exposure with high oxygen concentration on glucose and insulin levels and skeletal muscle-fiber properties were investigated in type 2 diabetic Goto-Kakizaki rats. Five-week-old rats were exposed to a hyperbaric environment (1.25 atmospheric pressure) with a high oxygen concentration (36%) fo...

journal_title：Muscle & nerve

authors： Yasuda K,Adachi T,Gu N,Matsumoto A,Matsunaga T,Tsujimoto G,Tsuda K,Ishihara A

更新日期：2007-03-01 00:00:00

abstract：:Using poststimulus time histograms, it has been reported that stimulation of the median nerve at the elbow produces a monosynaptic EPSP in voluntarily active single motoneurons of the human biceps brachii. The present study was undertaken to: (i) determine whether such stimulation could evoke a reproducible reflex res...

journal_title：Muscle & nerve

authors： Miller TA,Mogyoros I,Burke D

更新日期：1995-06-01 00:00:00

abstract：INTRODUCTION:Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders. METHODS:We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of cl...

journal_title：Muscle & nerve

authors： Lieba-Samal D,Jengojan S,Kasprian G,Wöber C,Bodner G

更新日期：2016-12-01 00:00:00

abstract：:A small-scale procedure for preparing tightly coupled intact skeletal muscle mitochondria from myodystrophic (myd/myd) mice is described. Mitochondrial preparations derived from heart, liver, and skeletal muscle of myd/myd and their littermate (+/?) controls are characterized with respect to their cytochrome content a...

journal_title：Muscle & nerve

authors： Lee CP,Martens ME,Jankulovska L,Neymark MA

更新日期：1979-09-01 00:00:00

abstract：:We studied the effect of a gluten-free diet in patients with idiopathic sensorimotor axonal neuropathy and circulating antigliadin antibodies. Consecutive patients underwent baseline neurophysiological assessment and were offered a gluten-free diet. Those who went on the diet formed the intention-to-treat group and th...

journal_title：Muscle & nerve

authors： Hadjivassiliou M,Kandler RH,Chattopadhyay AK,Davies-Jones AG,Jarratt JA,Sanders DS,Sharrack B,Grünewald RA

更新日期：2006-12-01 00:00:00

abstract：:The aim of this study was to investigate possible influences of suprasegmental lesions on the masseter reflex. The masseter reflex was elicited in 54 patients with supratentorial (37 patients) or cerebellar (17 patients) lesions 3-11 days after the acute onset of clinical disease. Patients showing lesions within the p...

journal_title：Muscle & nerve

authors： Hopf HC,Hinrichs C,Stoeter P,Urban PP,Marx J,Thömke F

更新日期：2000-01-01 00:00:00

abstract：:Acquired neuromyotonia is characterized by hyperexcitability of motor nerves resulting in continuous muscle fiber activity. It occurs most often as a paraneoplastic syndrome in patients with cancers of the immune system. Antibodies against voltage-gated potassium channels (VGKCs) have been detected in some patients. P...

journal_title：Muscle & nerve

authors： Lahrmann H,Albrecht G,Drlicek M,Oberndorfer S,Urbanits S,Wanschitz J,Zifko UA,Grisold W

更新日期：2001-06-01 00:00:00

abstract：INTRODUCTION:Meralgia paresthetica is a common clinical complaint for which some patients ultimately undergo surgical treatment. The lateral femoral cutaneous nerve (LFCN) has been difficult to reliably test electrophysiologically, likely due to anatomic variability and lack of responses in asymptomatic obese subjects....

journal_title：Muscle & nerve

authors： Boon AJ,Bailey PW,Smith J,Sorenson EJ,Harper CM,Hurdle MF

更新日期：2011-10-01 00:00:00

abstract：:A treatment has been developed to alleviate muscle weakness in murine dystrophy. Cultured myoblasts from genetically normal mouse embryos were injected into the right soleus of 20-day-old normal or dystrophic mice. Hosts and donors were immunocompatible but exhibited different genotype markers. Donor cells produced GP...

journal_title：Muscle & nerve

authors： Law PK,Goodwin TG,Wang MG

更新日期：1988-06-01 00:00:00

abstract：:Excitability properties were recorded from 14 volunteers following stimulation of the recurrent motor branch of the median nerve in the palm. Distal stimulation resulted in significantly lower strength-duration time constant and lower threshold during prolonged hyperpolarization than did wrist stimulation in the same ...

journal_title：Muscle & nerve

authors： Walters RJ,Kiernan MC,Murray NM,Bostock H

更新日期：2001-12-01 00:00:00

abstract：:Ion channels are complex proteins that span the lipid bilayer of the cell membrane, where they orchestrate the electrical signals necessary for normal function of the central nervous system, peripheral nerve, and both skeletal and cardiac muscle. The role of ion channel defects in the pathogenesis of numerous disorder...

journal_title：Muscle & nerve

authors： Kleopa KA,Barchi RL

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:Despite the existence of guidelines, painful neuropathy is often inappropriately treated. We sought to determine the effectiveness of a clinical decision support system on guideline-recommended medication use. METHODS:We randomized neurology providers, stratified by subspecialty, to a best practice alert ...

journal_title：Muscle & nerve

authors： Reynolds EL,Burke JF,Banerjee M,Callaghan BC

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:We investigated the possible role of intercostal surgical neurolysis in relieving chronic neuropathic pain refractory to other nonsurgical treatments in patients with postsurgical thoracic pain. METHODS:We retrospectively collected clinical data on patients referred to the Neurosurgery Unit of Policlinic ...

journal_title：Muscle & nerve

authors： Cappellari AM,Tiberio F,Alicandro G,Spagnoli D,Grimoldi N

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Widespread musculoskeletal pain is a well-known symptom of myotonic dystrophy type 2 (DM2), but so far it has been addressed in only a few studies. METHODS:A postal survey for all traceable DM2 patients (n = 132) was conducted. A specific questionnaire, and severity and interference subscales of the Brief...

journal_title：Muscle & nerve

authors： Suokas KI,Haanpää M,Kautiainen H,Udd B,Hietaharju AJ

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:There have been few reports on subtypes of Guillain-Barré syndrome (GBS) in children. We compared clinical and laboratory findings of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN). METHODS:One hundred forty children with GBS were included. Based on...

journal_title：Muscle & nerve

authors： Kalita J,Kumar M,Misra UK

更新日期：2018-05-01 00:00:00

abstract：:Clinicopathologic findings from two golden retriever dogs with an inherited, progressive, degenerative muscle disease that were studied until 27 and 40 months of age are described. Initial clinical signs included stilted gait and simultaneous advancement of their pelvic limbs. Further gait restriction and muscle hyper...

journal_title：Muscle & nerve

authors： Kornegay JN,Tuler SM,Miller DM,Levesque DC

更新日期：1988-10-01 00:00:00

abstract：:Repetitive nerve stimulation (RNS) of the median nerve is rarely studied in myasthenia gravis (MG). We performed a retrospective analysis of RNS studies performed on 448 patients at our center between 2010 and 2016. Among 95 patients with MG, an abnormal decrement of the compound muscle action potential amplitude was ...

journal_title：Muscle & nerve

authors： Lee TH,Li Y

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Far-field potentials (FFPs) from muscles other than the abductor digiti minimi (ADM) may interfere with motor unit number estimation (MUNE) from that muscle. METHODS:We identified the origin of each surface motor unit potential (SMUP) during hypothenar MUNE using the multiple point stimulation method in 2...

journal_title：Muscle & nerve

authors： Kawamura Y,Sonoo M,Higashihara M,Chiba T,Hatanaka Y

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Patients with DMD have low bone mineral density (BMD) and are at high risk for fractures. We examined changes in BMD and the effects of alendronate in DMD patients treated at our institution in the last decade. METHODS:Retrospective cohort study of 39 DMD patients. RESULTS:Patients had screening dual ene...

journal_title：Muscle & nerve

authors： Houston C,Mathews K,Shibli-Rahhal A

更新日期：2014-04-01 00:00:00

abstract：INTRODUCTION:In this study we aimed to determine the maximal isometric muscle strength of a healthy, normal-weight, pediatric population between 6 and 15 years of age using hand-held dynamometry to establish strength reference values. The secondary objective was determining the relationship between strength and anthrop...

journal_title：Muscle & nerve

authors： Escobar RG,Munoz KT,Dominguez A,Banados P,Bravo MJ

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Factors determining response to intravenous immunoglobulin (IVIg) and plasmapheresis in myasthenia gravis (MG) have not been evaluated systematically. METHODS:This study included patients treated with IVIg (n = 63) or plasmapheresis (n = 42) from two trials evaluating IVIg vs. placebo or plasmapheresis in...

journal_title：Muscle & nerve

authors： Katzberg HD,Barnett C,Bril V

更新日期：2012-05-01 00:00:00