Abstract:
:Acquired neuromyotonia is characterized by hyperexcitability of motor nerves resulting in continuous muscle fiber activity. It occurs most often as a paraneoplastic syndrome in patients with cancers of the immune system. Antibodies against voltage-gated potassium channels (VGKCs) have been detected in some patients. Peripheral neuropathy is sometimes present. We report on a patient with Hodgkin's lymphoma in complete remission who developed paresthesias followed by neuromyotonia with bulbar involvement. Peripheral sensorimotor neuropathy was diagnosed electrophysiologically and evidence of axonal degeneration and demyelination was detected by sural nerve biopsy. The patient's complaints, including dysarthria, improved after carbamazepine treatment.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Lahrmann H,Albrecht G,Drlicek M,Oberndorfer S,Urbanits S,Wanschitz J,Zifko UA,Grisold Wdoi
10.1002/mus.1078subject
Has Abstractpub_date
2001-06-01 00:00:00pages
834-8issue
6eissn
0148-639Xissn
1097-4598pii
10.1002/mus.1078journal_volume
24pub_type
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