Thymus imaging in myasthenia gravis: The relevance in clinical practice.

abstract：INTRODUCTION:Statins have well-known benefits on cardiovascular mortality, though up to 15% of patients experience side effects. With guidelines from the American Heart Association, American College of Cardiology, and American Diabetes Association expected to double the number of statin users, the overall incidence of ...

journal_title：Muscle & nerve

authors： Rengo JL,Callahan DM,Savage PD,Ades PA,Toth MJ

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:Pompe disease is a progressive and debilitating neuromuscular disorder that presents with a heterogeneous array of signs and symptoms including proximal muscle weakness, respiratory insufficiency, and/or elevated creatine kinase levels. It mimics other neuromuscular disorders, making its diagnosis challeng...

journal_title：Muscle & nerve

authors： Dubrovsky A,Corderi J,Karasarides T,Taratuto AL

更新日期：2013-04-01 00:00:00

abstract：:Chronic inflammatory demyelinating polyneuropathy (CIDP) presents in rare instances with focal or multifocal upper limb involvement. We reviewed the clinical and electromyographic (EMG) characteristics of 10 such patients (UL-CIDP) and compared them with patients with typical generalized CIDP (G-CIDP) and multifocal m...

journal_title：Muscle & nerve

authors： Gorson KC,Ropper AH,Weinberg DH

更新日期：1999-06-01 00:00:00

abstract：:Recurrent idiopathic lumbosacral plexopathy has rarely been reported in the literature. The present report describes a 59-year-old man presenting with recurrent episodes of acute leg pain, followed by weakness. After each episode, symptoms progressed for several months before peaking. Thereafter, gradual recovery ensu...

journal_title：Muscle & nerve

authors： Yee T

更新日期：2000-09-01 00:00:00

abstract：:The aim of this study was to investigate in control subjects the effect of imagery training on the torque of plantar-flexor muscles of the ankle. Twenty-nine subjects were allocated to one of three groups that performed either imagery training, low-intensity strength training, or no training (only measurements). The l...

journal_title：Muscle & nerve

authors： Zijdewind I,Toering ST,Bessem B,Van Der Laan O,Diercks RL

更新日期：2003-08-01 00:00:00

abstract：:We describe a patient who developed seropositive myasthenia gravis 16 years after she was diagnosed with autoimmune premature ovarian failure with antibodies to the receptor for follicle-stimulating hormone (FSH). Although thymectomy led to improvement of her myasthenic symptoms, menses did not resume. Such combined s...

journal_title：Muscle & nerve

authors： Ryan MM,Jones HR Jr

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) subjects ≥5 years with nonsense mutations were followed for 48 weeks in a multicenter, randomized, double-blind, placebo-controlled trial of ataluren. Placebo arm data (N = 57) provided insight into the natural history of the 6-minute walk test (6MWT) and other endpoints. ...

journal_title：Muscle & nerve

authors： McDonald CM,Henricson EK,Abresch RT,Florence JM,Eagle M,Gappmaier E,Glanzman AM,PTC124-GD-007-DMD Study Group.,Spiegel R,Barth J,Elfring G,Reha A,Peltz S

更新日期：2013-09-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) is characterized by absence of the subsarcolemmal protein dystrophin, present in skeletal muscles and cardiomyocytes. We hypothesized that progressive respiratory and left ventricular (LV) insufficiencies in DMD could be parallel and interrelated phenomena. METHODS:We con...

journal_title：Muscle & nerve

authors： Khokhar A,Nair A,Midya V,Kumar A,Sinharoy A,Ahmad TA,Abu-Hasan M,Mondal P

更新日期：2019-09-01 00:00:00

abstract：:A stand-alone ultrasound shear wave imaging technology has been developed to quantify and visualize Young's modulus distribution by remotely applying ultrasound radiation force and tracking the resulting microvibrations in soft tissues with ultrafast ultrasound imaging. We report the first preliminary data that detect...

journal_title：Muscle & nerve

authors： Shinohara M,Sabra K,Gennisson JL,Fink M,Tanter M

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:Myotonic dystrophy, or dystrophia myotonica (DM), is characterized by prominent muscle wasting and weakness as well as delayed muscle relaxation resulting from persistent electrical discharges. METHODS:We hypothesized heterogeneity among muscles in degree of weakness and myotonia in an expanded [(CUG)(250...

journal_title：Muscle & nerve

authors： Moyer M,Berger DS,Ladd AN,Van Lunteren E

更新日期：2011-06-01 00:00:00

abstract：:Single-fiber electromyography (SFEMG) demonstrates abnormal jitter in virtually all (99%) patients with myasthenia gravis (MG). One muscle, the extensor digitorum communis, is abnormal in most patients with this disease, but to obtain the maximum diagnostic sensitivity, it may be necessary to examine other muscles, es...

journal_title：Muscle & nerve

authors： Sanders DB,Howard JF Jr

更新日期：1986-11-01 00:00:00

abstract：:At least 50 disease-causing mutations in the skeletal muscle voltage-gated chloride channel gene (CLCN1), almost all of which originate from Caucasian families, have been identified. We investigated a Japanese family with Thomsen's myotonia congenita that included 16 affected individuals (8 men and 8 women) through fi...

journal_title：Muscle & nerve

authors： Sasaki R,Ito N,Shimamura M,Murakami T,Kuzuhara S,Uchino M,Uyama E

更新日期：2001-03-01 00:00:00

abstract：:Intravascular lymphomatosis, also known as endovascular lymphoma or angiotropic large cell lymphoma, is a rare malignancy typically diagnosed at autopsy. We describe a case in which the diagnosis was made at an early stage. Specific electrodiagnostic findings suggested concomitant polyneuropathy and myopathy. Suspicio...

journal_title：Muscle & nerve

authors： Oei ME,Kraft GH,Sarnat HB

更新日期：2002-05-01 00:00:00

abstract：INTRODUCTION:Muscle changes in patients with diabetes and lower leg pain due to chronic exertional compartment syndrome (CECS) were investigated before and after fasciotomy. METHODS:The tibialis anterior muscle was analyzed with histochemical and morphological techniques in 7 patients with diabetes and CECS before fas...

journal_title：Muscle & nerve

authors： Edmundsson DS,Toolanen GL,Stål PS

更新日期：2018-02-01 00:00:00

abstract：:Several approaches to treat laminin alpha2 chain-deficient congenital muscular dystrophy (MDC1A) in mouse models have been undertaken. Most have shown promising results in young animals. However, older animals have only been characterized to some extent. Herein we analyze the lifespan of laminin alpha2 chain-deficient...

journal_title：Muscle & nerve

authors： Gawlik KI,Durbeej M

更新日期：2010-07-01 00:00:00

abstract：:New developments in the rapid diagnosis and treatment of boys with Duchenne muscular dystrophy (DMD) have led to growing enthusiasm for instituting DMD newborn screening (NBS) in the United States. Our group has been interested in developing clinical guidance to be implemented consistently in specialty care clinics ch...

journal_title：Muscle & nerve

authors： Kwon JM,Abdel-Hamid HZ,Al-Zaidy SA,Mendell JR,Kennedy A,Kinnett K,Cwik VA,Street N,Bolen J,Day JW,Connolly AM

更新日期：2016-08-01 00:00:00

abstract：:The recommendations for clinical research standards published in 2000 by a task force of the Medical Scientific Advisory Board (MSAB) of the Myasthenia Gravis Foundation of America (MGFA) were largely successful in introducing greater uniformity in the recording and reporting of MG clinical trials. Recognizing that ch...

journal_title：Muscle & nerve

authors： Benatar M,Sanders DB,Burns TM,Cutter GR,Guptill JT,Baggi F,Kaminski HJ,Mantegazza R,Meriggioli MN,Quan J,Wolfe GI,Task Force on MG Study Design of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Anti-cytosolic 5'-nucleotidase 1A (cN1A) antibodies are commonly detected in patients with sporadic inclusion body myositis (sIBM). However, their pathogenic role has not been established. Moreover, efforts toward identifying sIBM distinct clinicopathologic characteristics associated with these antibodies ha...

journal_title：Muscle & nerve

authors： Paul P,Liewluck T,Ernste FC,Mandrekar J,Milone M

更新日期：2020-12-29 00:00:00

abstract：:The loss of muscle strength with aging appears to be greater in the lower than upper limbs, but strength and its neural control have never been compared in the same population of individuals in both upper and lower limbs. The aim of this study was to investigate differences between eight young (20-31 years) and eight ...

journal_title：Muscle & nerve

authors： Bazzucchi I,Felici F,Macaluso A,De Vito G

更新日期：2004-11-01 00:00:00

abstract：:L1 radiculopathy is very rare and difficult to diagnose with needle electromyography. A patient presented with pain and hypesthesia on the anterolateral aspect of the left thigh. Nerve conduction studies and needle electromyography were normal, except for the quadratus lumborum and iliopsoas muscles, which showed abno...

journal_title：Muscle & nerve

authors： Yang SN,Kim DH

更新日期：2010-04-01 00:00:00

abstract：:It has been suggested that vibration causes small changes in muscle length, but to the best of our knowledge, these have yet to be demonstrated during whole-body vibration (WBV). This was an observational study to determine whether acute WBV would result in muscle lengthening. We hypothesized that acute WBV would incr...

journal_title：Muscle & nerve

authors： Cochrane DJ,Loram ID,Stannard SR,Rittweger J

更新日期：2009-09-01 00:00:00

abstract：:A mathematical model is presented that predicts the electric field induced in the arm during magnetic stimulation of a peripheral nerve. The arm is represented as a homogeneous, cylindrical volume conductor. The electric field arises from two sources: the time-varying magnetic field and the accumulation of charge on t...

journal_title：Muscle & nerve

authors： Roth BJ,Cohen LG,Hallett M,Friauf W,Basser PJ

更新日期：1990-08-01 00:00:00

abstract：:We measured the peak voltage induced in a sensing loop by a Magstim 200 magnetic stimulator. Coil output varied little for repeated stimulation at the same intensity over a wide range of coil output. In contrast, the first stimulus immediately after a change in intensity was of larger amplitude and showed greater vari...

journal_title：Muscle & nerve

authors： Reutens DC,MacDonell RA,Berkovic SF

更新日期：1993-12-01 00:00:00

abstract：:A quantitative assessment was made of the firing characteristics of repetitive axonal discharges encountered during microneurographic recordings from human peripheral nerves. Spontaneous activity was recorded from 16 single axons using tungsten microelectrodes inserted percutaneously into fascicles of the median or pe...

journal_title：Muscle & nerve

authors： Macefield VG

更新日期：1998-04-01 00:00:00

abstract：:We used Southern blot analysis and the polymerase chain reaction to analyze the tissue distribution of multiple mitochondrial DNA (mtDNA) deletions in a 45-year-old man with familial mitochondrial myopathy-Southern blots showed two major types of abnormal mtDNA with approximately 4- and 8-kilobase deletions in the ske...

journal_title：Muscle & nerve

authors： Kawashima S,Ohta S,Kagawa Y,Yoshida M,Nishizawa M

更新日期：1994-07-01 00:00:00

abstract：:Insights into how the nervous system functions have often sprung from knowledge of the localization of nervous system diseases. Indeed, the recent rebirth of behavioral neurology has been sparked by new insights into the topography of higher cortical functions. Yet, the localization of disease affecting the peripheral...

journal_title：Muscle & nerve

authors： Sabin TD

更新日期：1986-10-01 00:00:00

abstract：:Six members originating from two families with hereditary motor and sensory neuropathy (hypertrophic and neuronal types) were noted to have enlarged calf muscles. Muscle computed tomography revealed that muscle enlargement in the propositus of the family with the hypertrophic type of HMSN was due to an increase in mus...

journal_title：Muscle & nerve

authors： De Visser M,Hoogendijk JE,Ongerboer BW,Verbeeten BJ Jr

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:We describe the ultrasonographic findings of sciatic nerve endometriosis. METHODS:Two premenopausal women with catamenial sciatica symptoms were examined, the first without a history of endometriosis, the second with previously confirmed endometriosis of the ovary. Ultrasonography, extending from the scia...

journal_title：Muscle & nerve

authors： Arányi Z,Polyák I,Tóth N,Vermes G,Göcsei Z

更新日期：2016-09-01 00:00:00

abstract：:Forty patients with polymyositis or dermatomyositis underwent detailed electromyographic evaluation. The paraspinal muscles of all patients were examined, as were several extremity muscles. The distribution of fibrillation potentials (FPs) in different muscles is discussed. FPs were most frequent in paraspinal muscles...

journal_title：Muscle & nerve

authors： Streib EW,Wilbourn AJ,Mitsumoto H

更新日期：1979-01-01 00:00:00

abstract：:Bcl-2 and Bax immunohistochemistry was examined in the skeletal muscle of rats after cutting the sciatic nerve, as a model of denervation and reinnervation, and in the anterior tibialis muscle of rats after an intramuscular injection of metoclopramide, as a model of necrosis and regeneration of muscle fibers, to bette...

journal_title：Muscle & nerve

authors： Olivé M,Ferrer I

更新日期：2000-12-01 00:00:00