Abstract:
INTRODUCTION:Muscle changes in patients with diabetes and lower leg pain due to chronic exertional compartment syndrome (CECS) were investigated before and after fasciotomy. METHODS:The tibialis anterior muscle was analyzed with histochemical and morphological techniques in 7 patients with diabetes and CECS before fasciotomy and in 5 of them 1 year after fasciotomy. Nondiabetic patients with CECS and healthy participants served as references. RESULTS:Before treatment, walking distance until occurrence of pain was limited (<0.2 km). Intramuscular pressure was significantly higher than in reference participants. Muscle analysis showed changes pathognomonic for neuropathy and myopathy and a restricted capillary network, with significantly more severe changes in the muscles of patients with diabetes than in the muscles of nondiabetic patients. Treatment with fasciotomy improved clinical signs, increased walking ability, and reduced muscle abnormalities, but muscle capillarization remained low. DISCUSSION:Patients with diabetes and CECS have distinct pathological changes in affected muscles. Pressure-relieving fasciotomy triggers a regenerative response in the muscle tissue but not in the capillary bed. Muscle Nerve 57: 229-239, 2018.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Edmundsson DS,Toolanen GL,Stål PSdoi
10.1002/mus.25715subject
Has Abstractpub_date
2018-02-01 00:00:00pages
229-239issue
2eissn
0148-639Xissn
1097-4598journal_volume
57pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract::The distinction between chronic demyelinating polyneuropathies associated with IgM paraproteinemia and anti-myelin-associated glycoprotein (MAG) antibodies (MAG-PN) and chronic inflammatory demyelinating polyneuropathies (CIDPs) relies on the anti-MAG antibodies assay. The aim of the study was to identify clinical and...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20230
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:In compressive neuropathies, large myelinated nerve fibers are generally thought to be more susceptible. In this study, we investigated small myelinated Aδ and unmyelinated C fiber function in patients with mild, moderate, and severe carpal tunnel syndrome. METHODS:Forty-four healthy controls and 81 carpa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25592
更新日期:2017-10-01 00:00:00
abstract::A small-scale procedure for preparing tightly coupled intact skeletal muscle mitochondria from myodystrophic (myd/myd) mice is described. Mitochondrial preparations derived from heart, liver, and skeletal muscle of myd/myd and their littermate (+/?) controls are characterized with respect to their cytochrome content a...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880020504
更新日期:1979-09-01 00:00:00
abstract::Muscle of donor origin was formed after implantation of H-2Kb-tsA58 muscle precursor cells (mpc) into irradiated mdx nu/nu mouse muscles. A series of injections of the myotoxin, notexin, which destroys mature muscle fibers but spares muscle precursor cells and other tissues, was made into the mpc-injected muscles, lea...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199902)22:2<174::aid-mus5>
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:The radial nerve and posterior interosseous nerve (PIN) are prone to injury at multiple sites. Electrodiagnostic (EDx) studies may only identify the most proximal lesion. Nerve ultrasound could augment EDx by visualizing additional pathology. METHODS:This investigation was a retrospective examination of u...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24778
更新日期:2016-03-01 00:00:00
abstract:INTRODUCTION:We report preliminary findings of nerve ultrasound in patients with cerebellar ataxia neuropathy vestibular areflexia syndrome (CANVAS) who have sensory impairment due to dorsal root ganglionopathy. METHODS:The ultrasound cross-sectional area (CSA) of median and ulnar nerves of 7 CANVAS patients was compa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25476
更新日期:2017-07-01 00:00:00
abstract::Variable-frequency stimulation trains (VFTs) that take advantage of the catchlike property of skeletal muscle have been shown to augment the force production of fatigued muscles compared with constant-frequency trains (CFTs). The present study is the first to report the force augmentation produced by VFTs after fatigu...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199809)21:9<1145::aid-mus5
更新日期:1998-09-01 00:00:00
abstract::Left spinal accessory nerve palsy occurred in a young man when he quickly turned his head to the right while his shoulders were pulled down by heavy hand-held objects. Electrophysiologic studies demonstrated partial axonotmesis of the spinal accessory nerve branches innervating the sternocleidomastoid and upper and mi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110210
更新日期:1988-02-01 00:00:00
abstract::Motor involvement in acute herpes zoster is considered rare, but its incidence is unknown. In a sample of 40 patients with acute herpes zoster of varying severity, an abnormal electromyogram (EMG) (fibrillation, positive waves, high-frequency discharges) was found in 21 (53%), suggesting extension of inflammation to t...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199711)20:11<1433::aid-mus
更新日期:1997-11-01 00:00:00
abstract::We present three new and 14 retrospective cases of polyradiculopathy in sarcoidosis. Of these, 71% had weakness and 59% areflexia of the lower extremities, and 35% had sphincter dysfunction. Cases often were associated with central nervous system sarcoidosis. All cases involved thoracolumbar or lumbosacral roots, exce...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-4598(199905)22:5<608::aid-mus9>
更新日期:1999-05-01 00:00:00
abstract::A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880161118
更新日期:1993-11-01 00:00:00
abstract:INTRODUCTION:Paraneoplastic lower motor neuronopathies have been reported rarely with Hodgkin lymphoma. METHODS:We report a case of rapidly progressive motor neuronopathy preceding the diagnosis of Hodgkin lymphoma. RESULTS:A 31-year-old woman developed subacute rapidly progressive quadriparesis. Electrodiagnostic st...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23464
更新日期:2012-11-01 00:00:00
abstract:INTRODUCTION:Balance impairment contributes to gait dysfunction, falls, and reduced quality of life in adults with Charcot-Marie-Tooth disease (CMT) but has been minimally examined in pediatric CMT. METHODS:The CMT Pediatric Scale (CMTPedS) was administered to 520 children with CMT. Associations between balance functi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26500
更新日期:2019-09-01 00:00:00
abstract::We have assessed the reliability of hand-held myometry in 33 patients with spinal muscular atrophy (SMA), testing elbow flexion, handgrip, three-point pinch, knee flexion, knee extension, and foot dorsiflexion, and determining intraclass correlation coefficients (ICC). Interrater reliability was high for upper limbs, ...
journal_title:Muscle & nerve
pub_type: 杂志文章,多中心研究
doi:10.1002/mus.10166
更新日期:2002-07-01 00:00:00
abstract::Multifocal motor neuropathy (MMN) is a chronic, immune-mediate, peripheral myelinopathy. Inherent in its name, MMN implies involvement of two or more motor nerves. We report three patients with weakness and partial motor conduction block restricted to a single nerve and localized to sites that are not at risk for entr...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10088
更新日期:2002-05-01 00:00:00
abstract::Earlier studies have shown that prior denervation of muscle prevents myotonia induced by 2,4-dichlorophenoxy acetic acid (2,4-D) both in vivo and in vitro. This work studied the effect of reinnervation on 2,4-D myotonia. Twenty Sprague-Dawley rats were injected with 2,4-D at specific intervals following unilateral sci...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880090414
更新日期:1986-05-01 00:00:00
abstract:BACKGROUND:We aimed at evaluating the differential involvement of large myelinated Aβ-, small myelinated Aδ-, and unmyelinated C-fibers in patients with diabetic polyneuropathy and how they contribute to neuropathic pain. METHODS:We collected clinical and diagnostic test variables in 133 consecutive patients with diab...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27080
更新日期:2021-01-01 00:00:00
abstract::In this study we present 3 families with malignant hyperthermia (MH), all of Indian subcontinent descent. One individual from each of these families was fully sequenced for RYR1 and presented with the non-synonymous change c.11315G>A/p.R3772Q. When present in the homozygous state c.11315*A is associated with myopathic...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21397
更新日期:2009-10-01 00:00:00
abstract:INTRODUCTION:Evaluation of nerve mechanical properties has the potential to improve assessment of nerve impairment. Shear wave velocity, as measured by using shear wave (SW) ultrasound elastography, is a promising indicator of nerve mechanical properties such as stiffness. However, elucidation of external factors that ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26842
更新日期:2020-05-01 00:00:00
abstract::Single fiber electromyography ( SFEMG ) of the extensor digitorum communis (EDC) muscle and nerve conduction studies were performed on healthy, active elderly men (66-77 years old) to assess age-related changes in neuromuscular physiology and the effect of long-term increased muscular activity on these changes. The fo...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880070403
更新日期:1984-05-01 00:00:00
abstract:INTRODUCTION:Lower limb strength has never been characterized separately for late-onset and adult myotonic dystrophy type 1 (DM1) phenotypes. METHODS:The purpose of this study was to: (1) describe and compare lower limb strength between the 2 DM1 phenotypes; and (2) compare the impairment profiles obtained from 2 asse...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25451
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION:Twenty-six patients with clinical symptoms of adult onset carnitine palmitoyltransferase II (CPTII) deficiency were examined. All patients had skeletal muscle CPTII enzyme activity levels indicative of heterozygosity for CPT2 mutations, however sequence analysis identified no pathogenic mutations within th...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23498
更新日期:2013-02-01 00:00:00
abstract::The influence of the recording site on the motor unit potentials (MUPs) was investigated in the brachial biceps muscle of 8 healthy subjects. The MUPs were recorded with a concentric needle electrode and analyzed with a new decomposition EMG program we call multi-MUP analysis. MUPs had shorter durations and smaller am...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880181207
更新日期:1995-12-01 00:00:00
abstract::To determine whether skeletal muscle oxidative metabolism is impaired in multiple sclerosis (MS), phosphorus magnetic resonance spectroscopy was used to measure the rate of intramuscular phosphocreatine (PCr) resynthesis following exercise in MS and controls. Thirteen MS patients underwent intermittent isometric tetan...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880170802
更新日期:1994-08-01 00:00:00
abstract:INTRODUCTION:The ability to distinguish between normal thymus, thymic hyperplasia, and thymoma should aid clinical management and decision making in patients with myasthenia gravis (MG). We sought to determine the accuracy of routine imaging in predicting thymic pathology. METHODS:We retrospectively analyzed records o...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26096
更新日期:2018-02-09 00:00:00
abstract::Ion channels are complex proteins that span the lipid bilayer of the cell membrane, where they orchestrate the electrical signals necessary for normal function of the central nervous system, peripheral nerve, and both skeletal and cardiac muscle. The role of ion channel defects in the pathogenesis of numerous disorder...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.10164
更新日期:2002-09-01 00:00:00
abstract::The sternocleidomastoid muscle (SCM) is one of the major muscles involved in producing abnormal head position in cervical dystonia patients. This study tested whether doxorubicin chemomyectomy, direct injection of doxorubicin into the SCM to permanently remove muscle fibers, has the potential to be a nonsurgical, perm...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199811)21:11<1457::aid-mus
更新日期:1998-11-01 00:00:00
abstract:INTRODUCTION:The involvement of small myelinated fibers in the early stages of diabetic neuropathy (DN) has been suggested, but few objective methods can identify minimal neuropathy. The purpose of this study was to determine whether there are differences in contact heat evoked potential (CHEP) parameters between healt...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.22192
更新日期:2011-12-01 00:00:00
abstract::The nosologic distinction between paramyotonia congenita and hyperkalemic periodic paralysis is somewhat blurred. Muscle membrane inexcitability induced by cooling seems to be characteristic of paramyotonia congenita. The effect of cooling on the maximal compound muscle action potential (CMAP) in patients with paramyo...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880090804
更新日期:1986-10-01 00:00:00
abstract::Bcl-2 and Bax immunohistochemistry was examined in the skeletal muscle of rats after cutting the sciatic nerve, as a model of denervation and reinnervation, and in the anterior tibialis muscle of rats after an intramuscular injection of metoclopramide, as a model of necrosis and regeneration of muscle fibers, to bette...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/1097-4598(200012)23:12<1862::aid-mus10>3.0
更新日期:2000-12-01 00:00:00