Abstract:
:Single fiber electromyography ( SFEMG ) of the extensor digitorum communis (EDC) muscle and nerve conduction studies were performed on healthy, active elderly men (66-77 years old) to assess age-related changes in neuromuscular physiology and the effect of long-term increased muscular activity on these changes. The following two groups were studied: a control group and a group composed of men with occupationally greater usage of hand extensors. Fiber density and mean jitter were essentially the same in both groups; however, in the hand-user group there was greater variability in mean jitter and a significant increase in the prevalence of potential pairs with increased jitter or blocking. In both groups, slower nerve conduction velocities and lower amplitudes of sensory and motor evoked potentials tended to correlate with increased jitter and fiber density. These electrophysiological changes in healthy aged men are consistent with an extremely mild process of nerve terminal denervation and reinnervation. Although long-term increased synaptic activity did not greatly alter the rate or extent of this process, it did produce a higher incidence of abnormal potential pairs and greater variability in mean jitter.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Shields RW Jr,Robbins N,Verrilli AA 3rddoi
10.1002/mus.880070403subject
Has Abstractpub_date
1984-05-01 00:00:00pages
273-7issue
4eissn
0148-639Xissn
1097-4598journal_volume
7pub_type
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