The effects of chronic muscular activity on age-related changes in single fiber electromyography.

Abstract:

:Single fiber electromyography ( SFEMG ) of the extensor digitorum communis (EDC) muscle and nerve conduction studies were performed on healthy, active elderly men (66-77 years old) to assess age-related changes in neuromuscular physiology and the effect of long-term increased muscular activity on these changes. The following two groups were studied: a control group and a group composed of men with occupationally greater usage of hand extensors. Fiber density and mean jitter were essentially the same in both groups; however, in the hand-user group there was greater variability in mean jitter and a significant increase in the prevalence of potential pairs with increased jitter or blocking. In both groups, slower nerve conduction velocities and lower amplitudes of sensory and motor evoked potentials tended to correlate with increased jitter and fiber density. These electrophysiological changes in healthy aged men are consistent with an extremely mild process of nerve terminal denervation and reinnervation. Although long-term increased synaptic activity did not greatly alter the rate or extent of this process, it did produce a higher incidence of abnormal potential pairs and greater variability in mean jitter.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Shields RW Jr,Robbins N,Verrilli AA 3rd

doi

10.1002/mus.880070403

subject

Has Abstract

pub_date

1984-05-01 00:00:00

pages

273-7

issue

4

eissn

0148-639X

issn

1097-4598

journal_volume

7

pub_type

杂志文章
  • Diffuse large B-cell lymphoma presenting as piriformis syndrome.

    abstract::Piriformis syndrome (PS) is a rare condition characterized by pain and paresthesia of the buttock, often radiating to the posterior thigh. A patient with sciatica that was clinically suspicious for PS, underwent diagnostic work-up. A diagnosis of diffuse large B-cell lymphoma with neurolymphomatosis (NL) was made. To ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21538

    authors: Ye BS,Sunwoo IN,Suh BC,Park JP,Shim DS,Kim SM

    更新日期:2010-03-01 00:00:00

  • CMAP dispersion, amplitude decay, and area decay in a normal population.

    abstract::The aim of this investigation was to define the boundaries of compound motor action potential (CMAP) dispersion, amplitude decay, and area decay in a control population and determine their dependence on external variables such as age and interelectrode distance. Measurements were made from median, ulnar, and common pe...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880161107

    authors: Taylor PK

    更新日期:1993-11-01 00:00:00

  • Pathophysiology of spastic paresis. I: Paresis and soft tissue changes.

    abstract::Spastic paresis follows chronic disruption of the central execution of volitional command. Motor function in patients with spastic paresis is subjected over time to three fundamental insults, of which the last two are avoidable: (1) the neural insult itself, which causes paresis, i.e., reduced voluntary motor unit rec...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.20284

    authors: Gracies JM

    更新日期:2005-05-01 00:00:00

  • Canine inflammatory myopathy: analysis of cellular infiltrates.

    abstract::Inflammatory myopathies (IMs) occur relatively frequently in dogs, and, with the exception of masticatory muscle myositis (MMM), have not been characterized. This study analyzed the distribution and types of cellular infiltrates in 21 cases of generalized IM, 3 cases of focal IM (MMM), and 1 case with features of both...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20043

    authors: Pumarola M,Moore PF,Shelton GD

    更新日期:2004-06-01 00:00:00

  • Electrical impedance myography in the diagnosis of radiculopathy.

    abstract:INTRODUCTION:We sought to determine whether electrical impedance myography (EIM) could serve as a diagnostic procedure for evaluation of radiculopathy. METHODS:Twenty-seven patients with clinically and radiologically diagnosed cervical or lumbosacral radiculopathy who met a "gold standard" definition underwent EIM and...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23833

    authors: Spieker AJ,Narayanaswami P,Fleming L,Keel JC,Muzin SC,Rutkove SB

    更新日期:2013-11-01 00:00:00

  • Quantitative measurement of muscle fiber composition in a normal population.

    abstract::To obtain normative muscle morphology data on a healthy population recruited from a population survey, we examined vastus lateralis biopsies from 58 men and 33 women, aged 26-67 years. Biopsies were measured with automated, computer-aided techniques. Data were analyzed according to gender and age, and the influence of...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/mus.10373

    authors: Toft I,Lindal S,Bønaa KH,Jenssen T

    更新日期:2003-07-01 00:00:00

  • Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves.

    abstract::It is important to know the effects of prolonged repetitive nerve stimulation (RNS) when it is used in neurophysiological studies. RNS with up to 100 supramaximal stimuli was given to the median, ulnar, and peroneal nerves of normal subjects and the ulnar nerves of subjects with early amyotrophic lateral sclerosis (AL...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21604

    authors: Baumann F,Henderson RD,Tremayne F,Hutchinson N,McCombe PA

    更新日期:2010-06-01 00:00:00

  • Acute Lyme neuropathy presenting with polyradicular pain, abdominal protrusion, and cranial neuropathy.

    abstract::A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880161118

    authors: Krishnamurthy KB,Liu GT,Logigian EL

    更新日期:1993-11-01 00:00:00

  • Sural nerve water in vivo in normal humans measured by magnetic resonance spectroscopy: relation to age, height, gender, and neurological profile.

    abstract::To enable the quantitative assessment of peripheral nerve structure and function, we determined the normal values for sural nerve hydration structure as measured by magnetic resonance proton imaging, and for neurological function with scores for neuropathic symptoms, signs, and nerve conduction properties. Normal huma...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880160311

    authors: Eaton RP,Sibbitt WL Jr,Bicknell JM,King MK,Griffey RH,Sibbitt RR

    更新日期:1993-03-01 00:00:00

  • Schwann cell changes and demyelination in chronic galactose neuropathy.

    abstract::Dystrophic changes of Schwann cells and demyelination occurred in rats with chronic nerve edema induced by feeding a galactose-rich diet for two years. The mechanism for edema is the sorbitol pathway which generates osmotically active polyols from galactose or glucose. The blood-nerve barrier impedes diffusion of macr...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880060309

    authors: Powell HC,Myers RR

    更新日期:1983-03-01 00:00:00

  • Motor neuron firing range, axonal conduction velocity, and muscle fiber histochemistry in neuromuscular diseases.

    abstract::The voluntary discharge properties and axonal conduction velocity of single motor units were studied in patients with neuromuscular diseases with retained differentiation of the muscle fibers into type 1 and type 2, and in patients with late-onset hereditary distal myopathy in which muscle fibers have only intermediat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880020603

    authors: Borg J,Grimby L,Hannerz J

    更新日期:1979-11-01 00:00:00

  • Inaccurate projection of rat soleus motoneurons: a comparison of nerve repair techniques.

    abstract::The objectives of this study were 1) to determine the degree to which soleus motoneurons find their appropriate target following crush and transection injuries to the sciatic nerve, and 2) to determine whether repair of a transected nerve with a silicone tube leads to greater specificity of reinnervation and recovery ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199701)20:1<29::aid-mus4>3

    authors: Bodine-Fowler SC,Meyer RS,Moskovitz A,Abrams R,Botte MJ

    更新日期:1997-01-01 00:00:00

  • Anticipation of autosomal dominant progressive external ophthalmoplegia with hypogonadism.

    abstract::A large Swedish family with members affected by progressive external ophthalmoplegia with hypogonadism were followed-up and reviewed. Hypogonadism included delayed sexual maturation, primary amenorrhea, early menopause, and testicular atrophy. Cataracts, cerebellar ataxia, neuropathy, hypoacusia, pes cavus, tremor, pa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-4598(199612)19:12<1561::AID-MUS

    authors: Melberg A,Arnell H,Dahl N,Stålberg E,Raininko R,Oldfors A,Bakall B,Lundberg PO,Holme E

    更新日期:1996-12-01 00:00:00

  • Soleus-specific myopathy induced by passive stretching under local tetanus.

    abstract::Twenty-four adult albino rats were injected with tetanus toxin into the right gastrocnemius muscle and then subjected to sustained dorsiflexion of the right ankle joint for 2 to 14 days. Histologic examinations of the soleus after this procedure showed myopathic changes, characterized by variations in fiber diameters,...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880131007

    authors: Mizuno Y,Chou SM

    更新日期:1990-10-01 00:00:00

  • Normal myoblast injections provide genetic treatment for murine dystrophy.

    abstract::A treatment has been developed to alleviate muscle weakness in murine dystrophy. Cultured myoblasts from genetically normal mouse embryos were injected into the right soleus of 20-day-old normal or dystrophic mice. Hosts and donors were immunocompatible but exhibited different genotype markers. Donor cells produced GP...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110602

    authors: Law PK,Goodwin TG,Wang MG

    更新日期:1988-06-01 00:00:00

  • Charcot-Marie-Tooth disease with intermediate conduction velocities caused by a novel mutation in the MPZ gene.

    abstract::Charcot-Marie-Tooth (CMT) disease is a heterogeneous group of inherited sensory and motor neuropathies. Mutations in the gene that encodes for myelin protein zero (MPZ) can produce different phenotypes: CMT1 (with low conduction velocities), CMT2 (less frequent and with unaffected conduction velocities), and CMTID (wi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21643

    authors: Banchs I,Casasnovas C,Montero J,Volpini V,Martínez-Matos JA

    更新日期:2010-08-01 00:00:00

  • Two-dimensional and shear wave elastography ultrasound: A reliable method to analyse spastic muscles?

    abstract:INTRODUCTION:Few data exist on the feasibility and reliability of measuring muscular atrophy in 2 dimensions (2D) by ultrasonography (US) and elasticity with shear wave elastography (SWE) in spastic muscles. METHODS:Fourteen patients with chronic stroke took part in 2 intersession reliability experiments performed wit...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25716

    authors: Mathevon L,Michel F,Aubry S,Testa R,Lapole T,Arnaudeau LF,Fernandez B,Parratte B,Calmels P

    更新日期:2018-02-01 00:00:00

  • Pompe disease, the must-not-miss diagnosis: A report of 3 patients.

    abstract:INTRODUCTION:Pompe disease is a progressive and debilitating neuromuscular disorder that presents with a heterogeneous array of signs and symptoms including proximal muscle weakness, respiratory insufficiency, and/or elevated creatine kinase levels. It mimics other neuromuscular disorders, making its diagnosis challeng...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23643

    authors: Dubrovsky A,Corderi J,Karasarides T,Taratuto AL

    更新日期:2013-04-01 00:00:00

  • Neural influence on slow muscle properties: inactivity with and without cross-reinnervation.

    abstract::The effects of altering (cross-reinnervation, CR) and/or eliminating (spinal isolation, SI) the activation-dependent neural input to the cat soleus for 8 months on its mechanical and biochemical properties were determined. The percent fast fibers was 0, 27, 38, and 54% for normal control (NC), NC-CR, SI, and SI-CR cat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-4598(199606)19:6<707::AID-MUS4>

    authors: Roy RR,Eldridge L,Baldwin KM,Edgerton VR

    更新日期:1996-06-01 00:00:00

  • Benefits of interval-training on fatigue and functional capacities in Charcot-Marie-Tooth disease.

    abstract::Exercise intolerance and undue fatigue are common complaints in patients with Charcot-Marie-Tooth (CMT) disease. Reduced physical ability is due directly to the disease, but it is also due to physical deconditioning. The aim of this study was to test whether 24 weeks of interval-training exercise (ITE) cycling can sig...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/mus.20959

    authors: El Mhandi L,Millet GY,Calmels P,Richard A,Oullion R,Gautheron V,Féasson L

    更新日期:2008-05-01 00:00:00

  • Administration of insulin-like growth factor-I improves fatigue resistance of skeletal muscles from dystrophic mdx mice.

    abstract::Muscle fatigue occurs in many neuromuscular diseases, including the muscular dystrophies, and it contributes to a loss of functional capacity and reduced quality of life for affected patients. An improvement in fatigue resistance has been observed in diaphragm muscles of mdx mice following insulin-like growth factor-I...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20082

    authors: Gregorevic P,Plant DR,Lynch GS

    更新日期:2004-09-01 00:00:00

  • The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID-19 pandemic.

    abstract::The coronavirus disease 2019 (COVID-19) pandemic has resulted in the reorganization of health-care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies. The magnitude of the impact of this public health emergency on the...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.26902

    authors: Veerapandiyan A,Wagner KR,Apkon S,McDonald CM,Mathews KD,Parsons JA,Wong BL,Eichinger K,Shieh PB,Butterfield RJ,Rao VK,Smith EC,Proud CM,Connolly AM,Ciafaloni E

    更新日期:2020-07-01 00:00:00

  • Treadmill training-induced adaptations in muscle phenotype in persons with incomplete spinal cord injury.

    abstract::Body weight-supported treadmill (BWST) training has been shown to improve ambulatory capacity in persons with a spinal cord injury (SCI); however, the effect that BWST training has on skeletal muscle phenotype is unknown. We aimed to determine whether 6 months (three sessions/week) of BWST training in neurologically s...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/mus.20048

    authors: Stewart BG,Tarnopolsky MA,Hicks AL,McCartney N,Mahoney DJ,Staron RS,Phillips SM

    更新日期:2004-07-01 00:00:00

  • Neuromuscular responses of patients with multiple sclerosis.

    abstract::Muscle weakness, studied in 4 patients with multiple sclerosis (MS), was compared with values from normal subjects. Twitch occlusion showed that normal subjects could activate their muscles maximally, but patients rarely achieved greater than 60% activation. In both groups, motoneuron firing rates increased linearly w...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880151011

    authors: Rice CL,Vollmer TL,Bigland-Ritchie B

    更新日期:1992-10-01 00:00:00

  • Repeatability, consistency, and accuracy of hand-held dynamometry with and without fixation for measuring ankle plantarflexion strength in healthy adolescents and adults.

    abstract:INTRODUCTION:Hand-held dynamometry (HHD) is commonly used to measure ankle plantarflexion strength but has variable reliability measuring higher forces. Fixed HHD is suggested to improve reliability. We, therefore, compared the reliability, consistency, and accuracy of measuring plantarflexion strength. METHODS:Planta...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25576

    authors: Davis PR,McKay MJ,Baldwin JN,Burns J,Pareyson D,Rose KJ

    更新日期:2017-11-01 00:00:00

  • Real-time visualization of muscle stiffness distribution with ultrasound shear wave imaging during muscle contraction.

    abstract::A stand-alone ultrasound shear wave imaging technology has been developed to quantify and visualize Young's modulus distribution by remotely applying ultrasound radiation force and tracking the resulting microvibrations in soft tissues with ultrafast ultrasound imaging. We report the first preliminary data that detect...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21723

    authors: Shinohara M,Sabra K,Gennisson JL,Fink M,Tanter M

    更新日期:2010-09-01 00:00:00

  • Spontaneous and evoked ectopic discharges recorded from single human axons.

    abstract::A quantitative assessment was made of the firing characteristics of repetitive axonal discharges encountered during microneurographic recordings from human peripheral nerves. Spontaneous activity was recorded from 16 single axons using tungsten microelectrodes inserted percutaneously into fascicles of the median or pe...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199804)21:4<461::aid-mus4>

    authors: Macefield VG

    更新日期:1998-04-01 00:00:00

  • Congenital canine myasthenia gravis: II. Acetylcholine receptor metabolism.

    abstract::Acetylcholine receptor (AChR) metabolism was studied in muscle from juvenile and adult dogs with congenital myasthenia gravis (CMG) and their unaffected littermates. Although the amount of AChR in the junctional region of innervated CMG muscle fibers was 25% of normal, or less, denervation of CMG fibers resulted in th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880070905

    authors: Oda K,Lennon VA,Lambert EH,Palmer AC

    更新日期:1984-11-01 00:00:00

  • Safety of influenza vaccination in patients with myasthenia gravis: a population-based study.

    abstract::Influenza vaccination has been associated with adverse events including Guillain-Barré syndrome. Because the safety of influenza vaccination in patients with myasthenia gravis (MG) has not been established, some clinicians discourage vaccination for these patients. We explored whether the administration of influenza v...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21440

    authors: Zinman L,Thoma J,Kwong JC,Kopp A,Stukel TA,Juurlink DN

    更新日期:2009-12-01 00:00:00

  • Effects of isaxonine on skeletal muscle reinnervation in the rat: an electrophysiologic evaluation.

    abstract::Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880080205

    authors: Pecot-Dechavassine M,Mira JC

    更新日期:1985-02-01 00:00:00