Electrical impedance myography in the diagnosis of radiculopathy.


INTRODUCTION:We sought to determine whether electrical impedance myography (EIM) could serve as a diagnostic procedure for evaluation of radiculopathy. METHODS:Twenty-seven patients with clinically and radiologically diagnosed cervical or lumbosacral radiculopathy who met a "gold standard" definition underwent EIM and standard needle electromyography (EMG) of multiple upper or lower extremity muscles. RESULTS:EIM reactance values revealed consistent reductions in the radiculopathy-affected myotomal muscles as compared with those on the unaffected side; the degree of asymmetry was associated strongly with the degree of EMG abnormality (P < 0.001). EIM had a sensitivity of 64.5% and a specificity of 77.0%; in comparison, EMG had a sensitivity of 79.7% but a specificity of 69.7%. CONCLUSIONS:These findings support the potential for EIM to serve as a new non-invasive tool to assist in diagnosis of radiculopathy; however, further refinement of the technique is needed for this specific application.


Muscle Nerve


Muscle & nerve


Spieker AJ,Narayanaswami P,Fleming L,Keel JC,Muzin SC,Rutkove SB




Has Abstract


2013-11-01 00:00:00












  • Measurement of platelet-derived microparticle levels using an enzyme-linked immunosorbent assay in polymyositis and dermatomyositis patients.

    abstract::Platelet-derived microparticle (PDMP) levels were measured using an enzyme-linked immunosorbent assay (ELISA) to elucidate the role of platelet activation in patients with polymyositis or dermatomyositis (PM/DM). PDMP levels in active PM/DM patients (median 13.3 U/ml, interquartile range 9.9-20.7 U/ml, n = 16) and tho...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Shirafuji T,Hamaguchi H,Higuchi M,Kanda F

    更新日期:2009-05-01 00:00:00

  • Sural nerve biopsy studies in Leigh's subacute necrotizing encephalomyelopathy.

    abstract::Peripheral neuropathy marked by reduced nerve conduction velocities was found in four unrelated children, between the ages of 15 months and 9 years, whose autopsies revealed Leigh's subacute necrotizing encephalomyelopathy. Sural nerve biopsies disclosed primary demyelination and remyelination, as well as loss of myel...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Goebel HH,Bardosi A,Friede RL,Kohlschütter A,Albani M,Siemes H

    更新日期:1986-02-01 00:00:00

  • Skeletal muscle cell MHC I expression: implications for statin-induced myopathy.

    abstract::Statins can induce necrotizing or inflammatory myopathies in some patients. Increased major histocompatibility complex class I (MHC I) expression has been shown in muscle biopsies of statin-induced myopathy. Therefore, we investigated the effect of statins on the expression of MHC I in muscle cells. Using flow cytomet...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Singh P,Kohr D,Kaps M,Blaes F

    更新日期:2010-02-01 00:00:00

  • Orofacial strength, dysarthria, and dysphagia in congenital myotonic dystrophy.

    abstract:INTRODUCTION:Herein we present an exploratory study of orofacial function in children with congenital myotonic dystrophy (CDM) vs. healthy controls. METHODS:We evaluated 41 children with CDM and 29 healthy controls for speech and swallow function and for lingual and labial strength. RESULTS:The Iowa Oral Performance ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Berggren KN,Hung M,Dixon MM,Bounsanga J,Crockett B,Foye MD,Gu Y,Campbell C,Butterfield RJ,Johnson NE

    更新日期:2018-09-01 00:00:00

  • Differential response of heat shock proteins to hindlimb unloading and reloading in the soleus.

    abstract::Hindlimb unloading (HU) results in oxidative stress, skeletal muscle atrophy, and increased damage upon reloading. Heat shock proteins (HSPs) protect against oxidative stress. However, it is unknown whether HSPs are depressed with long-term unloading (28 days) or reloading. We tested the hypotheses that long-term HU w...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Lawler JM,Song W,Kwak HB

    更新日期:2006-02-01 00:00:00

  • Prospective comparison of acute motor axonal neuropathy and acute inflammatory demyelinating polyradiculoneuropathy in 140 children with Guillain-Barré syndrome in India.

    abstract:INTRODUCTION:There have been few reports on subtypes of Guillain-Barré syndrome (GBS) in children. We compared clinical and laboratory findings of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN). METHODS:One hundred forty children with GBS were included. Based on...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Kalita J,Kumar M,Misra UK

    更新日期:2018-05-01 00:00:00

  • A novel points system to predict the prognosis of ulnar neuropathy at the elbow.

    abstract:INTRODUCTION:In this study we aimed to identify prognostic factors of ulnar neuropathy at the elbow (UNE) and developed a scoring system to establish the prognosis. METHODS:We collected baseline clinical, electrophysiologic, and ultrasonographic data from 2 cohorts. The outcomes for all patients were determined on fol...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Beekman R,Zijlstra W,Visser LH

    更新日期:2017-05-01 00:00:00

  • Familial amyloid polyneuropathy in Taiwan: identification of transthyretin variant (Leu55-->Pro).

    abstract::We report a family with familial amyloid polyneuropathy (FAP), showing an early-onset and a fatal outcome before age 30. Transthyretin (TTR) gene analysis showed one point mutation (T-->C change) in the second base of codon 55, and the corresponding amino acid substitution of proline (Pro) for leucine (Leu) was confir...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Yamamoto K,Hsu SP,Yoshida K,Ikeda S,Nakazato M,Shiomi K,Cheng SY,Furihata K,Ueno I,Yanagisawa N

    更新日期:1994-06-01 00:00:00

  • Immunohistochemical characterization of human masseter muscle spindles.

    abstract::An enzyme- and immunohistochemical study has been performed on human masseter muscle spindles. Antibodies selective for different myosin heavy chain (MHC) isoforms and M-band proteins (M-protein, myomesin, and MM-CK) were used. The expression of these proteins was determined in the different intrafusal fiber types. Nu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Eriksson PO,Butler-Browne GS,Thornell LE

    更新日期:1994-01-01 00:00:00

  • Novel mutations in the gene encoding very long-chain acyl-CoA dehydrogenase identified in patients with partial carnitine palmitoyltransferase II deficiency.

    abstract:INTRODUCTION:Twenty-six patients with clinical symptoms of adult onset carnitine palmitoyltransferase II (CPTII) deficiency were examined. All patients had skeletal muscle CPTII enzyme activity levels indicative of heterozygosity for CPT2 mutations, however sequence analysis identified no pathogenic mutations within th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Isackson PJ,Sutton KA,Hostetler KY,Vladutiu GD

    更新日期:2013-02-01 00:00:00

  • Normative values and the effects of age, gender, and handedness on the Moberg Pick-Up Test.

    abstract::The Moberg Pick-Up Test is a standardized test for assessing hand dexterity. Although reduction of sensation in the hand occurs with aging, the effect of age on a subject's performance of the Moberg Pick-Up Test has not been examined. The primary goal of this study was to examine the impact of aging and, secondarily, ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Amirjani N,Ashworth NL,Gordon T,Edwards DC,Chan KM

    更新日期:2007-06-01 00:00:00

  • Muscle carnitine in hypo- and hyperthyroidism.

    abstract::Weakness is common in both hyper- and hypothyroidism, and skeletal muscle L-carnitine may play a role in this regard, as suggested by studies indicating abnormal levels of carnitine in serum and urine of patients with thyroid dysfunction. Skeletal muscle samples were obtained for carnitine analysis from control subjec...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Sinclair C,Gilchrist JM,Hennessey JV,Kandula M

    更新日期:2005-09-01 00:00:00

  • Myositis with antimitochondrial antibodies diagnosed by rectus abdominis muscle biopsy.

    abstract:INTRODUCTION:Antimitochondrial antibodies are autoantibodies detected in 90% of primary biliary cirrhosis (PBC) patients. Some PBC cases are complicated by myositis, which is difficult to confirm due to minimal histological evidence of inflammation in limb muscles. METHODS:Our aim was to determine the extent of inflam...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Uenaka T,Kowa H,Sekiguchi K,Nagata K,Ohtsuka Y,Kanda F,Toda T

    更新日期:2013-05-01 00:00:00

  • Two types of mitochondrial crystals in diseased human skeletal muscle fibers.

    abstract::Mitochondrial crystalline inclusions, frequently found in mitochondrial myopathies, were analyzed by crystallographic techniques and computer-aided image processing. It could be shown that these structures were real crystals. There are two distinct types of crystal, which can be distinguished by shape, size, and patte...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Farrants GW,Hovmöller S,Stadhouders AM

    更新日期:1988-01-01 00:00:00

  • Efficacy of limb cooling on the salvage of peripheral nerve from ischemic fiber degeneration.

    abstract::Since peripheral nerve has a large ischemic safety factor, hypothermia, by reducing metabolic demands, is potentially an efficacious technique to rescue nerve from ischemic fiber degeneration (IFD). We therefore evaluated the influence of temperature on the severity of IFD resulting from a standard ischemic stress. Is...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Kihara M,Schmelzer JD,Kihara Y,Smithson IL,Low PA

    更新日期:1996-02-01 00:00:00

  • Utility of ultrasound-guided surface electrode placement in lateral femoral cutaneous nerve conduction studies.

    abstract:INTRODUCTION:Meralgia paresthetica is a common clinical complaint for which some patients ultimately undergo surgical treatment. The lateral femoral cutaneous nerve (LFCN) has been difficult to reliably test electrophysiologically, likely due to anatomic variability and lack of responses in asymptomatic obese subjects....

    journal_title:Muscle & nerve

    pub_type: 杂志文章,随机对照试验


    authors: Boon AJ,Bailey PW,Smith J,Sorenson EJ,Harper CM,Hurdle MF

    更新日期:2011-10-01 00:00:00

  • A standardized clinical evaluation of patients affected by facioscapulohumeral muscular dystrophy: The FSHD clinical score.

    abstract::To define numerically the clinical severity of facioscapulohumeral muscular dystrophy (FSHD), we developed a protocol that quantifies muscle weakness by combining the functional evaluation of six muscle groups affected in this disease. To validate reproducibility of the protocol, 69 patients were recruited. Each patie...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Lamperti C,Fabbri G,Vercelli L,D'Amico R,Frusciante R,Bonifazi E,Fiorillo C,Borsato C,Cao M,Servida M,Greco F,Di Leo R,Volpi L,Manzoli C,Cudia P,Pastorello E,Ricciardi L,Siciliano G,Galluzzi G,Rodolico C,Santoro L

    更新日期:2010-08-01 00:00:00

  • Congenital canine myasthenia gravis: II. Acetylcholine receptor metabolism.

    abstract::Acetylcholine receptor (AChR) metabolism was studied in muscle from juvenile and adult dogs with congenital myasthenia gravis (CMG) and their unaffected littermates. Although the amount of AChR in the junctional region of innervated CMG muscle fibers was 25% of normal, or less, denervation of CMG fibers resulted in th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Oda K,Lennon VA,Lambert EH,Palmer AC

    更新日期:1984-11-01 00:00:00

  • Electrodiagnostic reference values for upper and lower limb nerve conduction studies in adult populations.

    abstract:INTRODUCTION:To address the need for greater standardization within the field of electrodiagnostic medicine, the Normative Data Task Force (NDTF) was formed to identify nerve conduction studies (NCS) in the literature, evaluate them using consensus-based methodological criteria derived by the NDTF, and identify those s...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Chen S,Andary M,Buschbacher R,Del Toro D,Smith B,So Y,Zimmermann K,Dillingham TR

    更新日期:2016-09-01 00:00:00

  • AAEE case report #19: ischemic monomelic neuropathy.

    abstract::A case study of a 50-year-old man who awakened from aortobifemoral bypass graft surgery with painful burning and numbness of the left foot is reported. Angiography showed embolic occlusion of the left popliteal artery proximal to the knee. Nerve conduction studies performed 1 year after occlusion showed loss or severe...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Levin KH

    更新日期:1989-10-01 00:00:00

  • A reliable technique for ultrasound-guided perineural injection in ulnar neuropathy at the elbow.

    abstract:INTRODUCTION:Ulnar neuropathy at the elbow (UNE) is a common peripheral compression neuropathy and, in most cases, occurs at 2 sites, the retroepicondylar groove or the cubital tunnel. With regard to a potential therapeutic approach with perineural corticosteroid injection, the aim of this study was to evaluate the dis...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Hamscha UM,Tinhofer I,Heber S,Grisold W,Weninger WJ,Meng S

    更新日期:2017-08-01 00:00:00

  • Ethical issues in the evaluation of adults with suspected genetic neuromuscular disorders.

    abstract::Genetic testing is rapidly becoming an increasingly significant part of the diagnostic armamentarium of neuromuscular clinicians. Although technically easy to order, the results of such testing, whether positive or negative, have potentially enormous consequences for the individual tested and for family members. As a ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Su X,Kang PB,Russell JA,Simmons Z

    更新日期:2016-12-01 00:00:00

  • Feasibility of Muscle Activity Assessment With Surface Electromyography During Bed Cycling Exercise In Intensive Care Unit Patients.

    abstract:INTRODUCTION:Intensive care unit (ICU) patients often develop weakness. Rehabilitation is initiated early to prevent physical deterioration, but knowledge of optimal training schedules is lacking. A reliable method to assess muscle activity during exercise is needed. In this study we explored the feasibility of electri...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Sommers J,Van Den Boorn M,Engelbert RHH,Nollet F,Van Der Schaaf M,Horn J

    更新日期:2018-11-01 00:00:00

  • Diffuse large B-cell lymphoma presenting as piriformis syndrome.

    abstract::Piriformis syndrome (PS) is a rare condition characterized by pain and paresthesia of the buttock, often radiating to the posterior thigh. A patient with sciatica that was clinically suspicious for PS, underwent diagnostic work-up. A diagnosis of diffuse large B-cell lymphoma with neurolymphomatosis (NL) was made. To ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Ye BS,Sunwoo IN,Suh BC,Park JP,Shim DS,Kim SM

    更新日期:2010-03-01 00:00:00

  • Depression of involuntary activity in muscles paralyzed by spinal cord injury.

    abstract::Involuntary muscle contractions are common after spinal cord injury (SCI). Increased sensitivity to Ia muscle afferent input may contribute to the development of these spasms. Since tendon vibration results in a period of postactivation depression of the Ia synapse, we sought to determine whether Achilles tendon vibra...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Butler JE,Godfrey S,Thomas CK

    更新日期:2006-05-01 00:00:00

  • Focal myositis presenting with radial nerve palsy.

    abstract::Focal myositis is a rare inflammatory pseudotumor of skeletal muscle which usually has a benign course. We report a 56-year-old woman with a painful mass in the left arm with a radial nerve palsy. Magnetic resonance imaging (MRI) of the left arm showed a mass in the triceps muscle that was suggestive of a soft-tissue ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Alzagatiti BI,Bertorini TE,Horner LH,Maccarino VS,O'Brien T

    更新日期:1999-07-01 00:00:00

  • Time and frequency domain analysis of acoustic signals from a human muscle.

    abstract::We wished to determine whether evoked force output from a human muscle could be inferred from the amplitude and the frequency of evoked muscular sounds. Sounds from adductor pollicis were recorded with a microphone and compared to evoked force changes produced by varying the intensity of nerve stimulation or of volunt...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Chen D,Durand LG,Bellemare F

    更新日期:1997-08-01 00:00:00

  • Time course of axonal regeneration in acute motor axonal neuropathy.

    abstract::Patients with acute motor axonal neuropathy (AMAN) generally recover well. We reviewed clinical and electrophysiologic recovery in 13 patients for up to 5 years. Twelve patients showed rapid recovery over 12 months, whereas in the remaining one the recovery was slow and incomplete at 5 years. In AMAN, axonal degenerat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Tamura N,Kuwabara S,Misawa S,Kanai K,Nakata M,Sawai S,Mori M,Hattori T

    更新日期:2007-06-01 00:00:00

  • Balance impairment in pediatric charcot-marie-tooth disease.

    abstract:INTRODUCTION:Balance impairment contributes to gait dysfunction, falls, and reduced quality of life in adults with Charcot-Marie-Tooth disease (CMT) but has been minimally examined in pediatric CMT. METHODS:The CMT Pediatric Scale (CMTPedS) was administered to 520 children with CMT. Associations between balance functi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Estilow T,Glanzman AM,Burns J,Harrington A,Cornett K,Menezes MP,Shy R,Moroni I,Pagliano E,Pareyson D,Bhandari T,Muntoni F,Laurá M,Reilly MM,Finkel RS,Eichinger KJ,Herrmann DN,Troutman G,Bray P,Halaki M,Shy ME,Yu

    更新日期:2019-09-01 00:00:00

  • Neuromyotonia, peripheral neuropathy and myasthenia gravis.

    abstract::A patient with neuromyotonia, peripheral neuropathy and myasthenia gravis (MG) is described. Neurophysiological studies, at rest, showed continuous muscle discharges of motor unit action potentials (MUAPs) in duplets and triplets. Motor (MNCV) and sensory (SNCV) nerve conduction studies revealed mild axonal and demyel...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Martinelli P,Patuelli A,Minardi C,Cau A,Riviera AM,Dal Pozzo F

    更新日期:1996-04-01 00:00:00