Turns-amplitude analysis in normal and myopathic facial muscles.


:The purpose of this study was to assess turns/amplitude analysis (TAA) as an objective alternative to conventional qualitative electromyography (EMG) for detection of myopathy in facial muscles. Normal values of TAA parameters were calculated in the frontalis and mentalis muscles of 26 control subjects. We estimated the slope of the regression line of mean amplitude/turn values (MA) plotted against the number of turns/second (NT) and the resulting clouds. The 95% confidence limits of the cloud data were drawn as an ellipse. The sensitivity of TAA was determined from a group of 35 myopathic patients and specificity from a second group of 25 control subjects. Significant differences for every TAA parameter were found between frontalis and mentalis. Cumulative sensitivity and specificity of TAA for frontalis and mentalis were 74.6%, 56.5%, and 73.3%, 70.8%, respectively. With at least two of the aforementioned criteria abnormal, the sensitivity and specificity for frontalis and mentalis were 61.3%, 82.6%, and 56.7%, 100.0%, respectively.


Muscle Nerve


Muscle & nerve


Karandreas N,Kararizou E,Papagianni A,Zambelis T,Kokotis P




Has Abstract


2011-03-01 00:00:00












  • Paraneoplastic lower motor neuronopathy associated with Hodgkin lymphoma.

    abstract:INTRODUCTION:Paraneoplastic lower motor neuronopathies have been reported rarely with Hodgkin lymphoma. METHODS:We report a case of rapidly progressive motor neuronopathy preceding the diagnosis of Hodgkin lymphoma. RESULTS:A 31-year-old woman developed subacute rapidly progressive quadriparesis. Electrodiagnostic st...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Flanagan EP,Sandroni P,Pittock SJ,Inwards DJ,Jones LK Jr

    更新日期:2012-11-01 00:00:00

  • Skeletal muscle cell MHC I expression: implications for statin-induced myopathy.

    abstract::Statins can induce necrotizing or inflammatory myopathies in some patients. Increased major histocompatibility complex class I (MHC I) expression has been shown in muscle biopsies of statin-induced myopathy. Therefore, we investigated the effect of statins on the expression of MHC I in muscle cells. Using flow cytomet...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Singh P,Kohr D,Kaps M,Blaes F

    更新日期:2010-02-01 00:00:00

  • Calcium paradox in skeletal muscles: physiologic and microscopic observations.

    abstract::Immersion of rat hemidiaphragms in Ca2+-free Krebs solution (KS) containing Ca2+ chelator in vitro leads to separation of basal lamina from the plasma membrane, as well as transient contracture and rapid loss of twitch response [calcium paradox (CP) phase 1]. Subsequent immersion in regular KS results in necrosis of m...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Soza M,Karpati G,Carpenter S

    更新日期:1986-03-01 00:00:00

  • Cortical and spinal mechanisms of facilitation to brain stimulation.

    abstract::Compound muscle action potentials (CMAPs) evoked by magnetic brain stimuli are larger if the subject provides a steady background voluntary contraction of the target muscle. This facilitation could be due either to cortical or spinal mechanisms, or both. Both magnetic and electrical stimuli given immediately after the...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Mills KR,Kimiskidis V

    更新日期:1996-08-01 00:00:00

  • Age-related differences in absolute numbers of skeletal muscle satellite cells.

    abstract::The absolute number of satellite cells (SC) in young and adult rat skeletal muscle was estimated by correlating data from light and electron microscopic quantitation of myofiber nuclei (myonuclei and satellite cell nuclei) with biochemical assays for determining total muscle DNA content. Expressed both as a proportion...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Gibson MC,Schultz E

    更新日期:1983-10-01 00:00:00

  • Effect of thermode application pressure on thermal threshold detection.

    abstract::Studies using quantitative sensory testing (QST) often present incongruent results due to intra- and intersubject as well as interobserver variability which limit widespread use of the technique. Eliminating or reducing the factors responsible for this variability is of great interest, as it increases reliability and ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Pavlaković G,Klinke I,Pavlaković H,Züchner K,Zapf A,Bachmann CG,Graf BM,Crozier TA

    更新日期:2008-11-01 00:00:00

  • Effects of isaxonine on skeletal muscle reinnervation in the rat: an electrophysiologic evaluation.

    abstract::Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Pecot-Dechavassine M,Mira JC

    更新日期:1985-02-01 00:00:00

  • Treadmill training-induced adaptations in muscle phenotype in persons with incomplete spinal cord injury.

    abstract::Body weight-supported treadmill (BWST) training has been shown to improve ambulatory capacity in persons with a spinal cord injury (SCI); however, the effect that BWST training has on skeletal muscle phenotype is unknown. We aimed to determine whether 6 months (three sessions/week) of BWST training in neurologically s...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章


    authors: Stewart BG,Tarnopolsky MA,Hicks AL,McCartney N,Mahoney DJ,Staron RS,Phillips SM

    更新日期:2004-07-01 00:00:00

  • Eosinophilic fasciitis with subjacent myositis.

    abstract:INTRODUCTION:Eosinophilic fasciitis (EF) is a rare disorder that can present with muscle symptoms that mimic other neuromuscular diseases. METHODS:We report the case of a 43-year-old woman with chronic muscle aches, tightness, and stiffness with hypertrophied, well-defined muscles despite physical inactivity, and thic...

    journal_title:Muscle & nerve



    authors: Whitlock JB,Dimberg EL,Selcen D,Rubin DI

    更新日期:2017-09-01 00:00:00

  • Anconeus motor unit number estimates using decomposition-based quantitative electromyography.

    abstract:INTRODUCTION:Motor unit number estimates (MUNEs) provide important information in health, aging, and disease, and can be determined using decomposition-enhanced spike-triggered averaging (DE-STA). Discrimination of surface-detected motor unit potentials (S-MUPs) has been limited to contractile forces of ∽30% maximum vo...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Stevens DE,Harwood B,Power GA,Doherty TJ,Rice CL

    更新日期:2014-07-01 00:00:00

  • Soleus-specific myopathy induced by passive stretching under local tetanus.

    abstract::Twenty-four adult albino rats were injected with tetanus toxin into the right gastrocnemius muscle and then subjected to sustained dorsiflexion of the right ankle joint for 2 to 14 days. Histologic examinations of the soleus after this procedure showed myopathic changes, characterized by variations in fiber diameters,...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Mizuno Y,Chou SM

    更新日期:1990-10-01 00:00:00

  • Adipose stem cells enhance myoblast proliferation via acetylcholine and extracellular signal-regulated kinase 1/2 signaling.

    abstract:INTRODUCTION:In this study we investigated the interaction between adipose tissue-derived stem cells (ASCs) and myoblasts in co-culture experiments. METHODS:Specific inductive media were used to differentiate ASCs in vitro into a Schwann cell-like phenotype (differentiated adipose tissue-derived stem cells, or dASCs) ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: El-Habta R,Kingham PJ,Backman LJ

    更新日期:2018-02-01 00:00:00

  • Needle electromyography of the frontalis muscle in patients with amyotrophic lateral sclerosis.

    abstract:INTRODUCTION:We sought to determine which muscles to choose for better assessment of the craniobulbar region in establishing the diagnosis of amyotrophic lateral sclerosis (ALS). METHODS:We studied the frontalis muscle in 83 controls and compared it with the tongue, sternocleidomastoid (SCM), and trapezius muscles in ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Pan H,Jian F,Lin J,Chen N,Zhang Z,Wang Y,Cui L,Kimura J

    更新日期:2016-12-01 00:00:00

  • Late-onset X-linked recessive spinal and bulbar muscular atrophy.

    abstract::A family is described in which five males have late-onset facial weakness, dysarthria, dysphagia, and slowly progressive proximal weakness. Electrodiagnostic studies and muscle biopsy were compatible with spinal muscular atrophy. This family appears quite similar to several previously reported families with late-onset...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Ringel SP,Lava NS,Treihaft MM,Lubs ML,Lubs HA

    更新日期:1978-07-01 00:00:00

  • Origin of surface motor unit potentials in hypothenar motor unit number estimation.

    abstract:INTRODUCTION:Far-field potentials (FFPs) from muscles other than the abductor digiti minimi (ADM) may interfere with motor unit number estimation (MUNE) from that muscle. METHODS:We identified the origin of each surface motor unit potential (SMUP) during hypothenar MUNE using the multiple point stimulation method in 2...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Kawamura Y,Sonoo M,Higashihara M,Chiba T,Hatanaka Y

    更新日期:2013-08-01 00:00:00

  • Demyelinating neuropathy with anti-CRMP5 antibodies predating diagnosis of breast carcinoma: favorable outcome after cancer therapy.

    abstract:INTRODUCTION:Breast cancer is exceptionally associated with anti-collapsin response mediator protein 5 (anti-CRMP5) antibody or demyelinating neuropathy. This paraneoplastic antibody is itself not associated with demyelinating neuropathy. METHODS:Herein we describe a patient with a predominantly sensory ataxic demyeli...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Samarasekera S,Rajabally YA

    更新日期:2011-05-01 00:00:00

  • Endocannabinoids and related lipids in serum from patients with amyotrophic lateral sclerosis.

    abstract:BACKGROUND:The goals of this study were to determine whether serum concentrations of endocannabinoids (eCB) and related lipids predict disease status in patients with amyotrophic lateral sclerosis (ALS) relative to healthy controls, and whether concentrations correlate with disease duration and severity. METHODS:Serum...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Carter GT,McLaughlin RJ,Cuttler C,Sauber GJ,Weeks DL,Hillard CJ,Weiss MD

    更新日期:2021-01-01 00:00:00

  • Electrophysiologic assessment of a median nerve injury in the palm.

    abstract::In median nerve lesions of the hand, electrophysiologic evaluation of the second lumbrical muscle can help to differentiate between lesions of the common digital nerves and the proper digital nerves, as illustrated by this case report. Median nerve conduction studies to the second lumbrical muscle can be performed by ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Busis NA,Logigian EL,Shahani BT

    更新日期:1986-03-01 00:00:00

  • Mechanically evoked sensory and motor responses to dynamic compression of the ulnar nerve.

    abstract::Mechanical deformation of a peripheral nerve can evoke action potentials in sensory and motor axons. The generation of these impulses with brief stimuli (<0.5 s) and their relationship to the deformation conditions have not been systematically studied in human subjects. Controlled compression stimuli over a range of a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Clarke EC,McNulty PA,Macefield VG,Bilston LE

    更新日期:2007-03-01 00:00:00

  • Endurance training improves skeletal muscle electrical activity in active COPD patients.

    abstract::The effect of endurance training on muscle electrical activity during general exercise testing was investigated in physically active patients with chronic obstructive pulmonary disease (COPD). Before and after rehabilitation, patients performed identical incremental exercise tests. Pulmonary gas exchange, venous lacta...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章


    authors: Gosselin N,Lambert K,Poulain M,Martin A,Préfaut C,Varray A

    更新日期:2003-12-01 00:00:00

  • Comparing the function of the corticospinal system in different species: organizational differences for motor specialization?

    abstract::An appreciation of the comparative functions of the corticospinal tract is of direct relevance to the understanding of how results from animal models can advance knowledge of the human motor system and its disorders. Two critical functions of the corticospinal tract are discussed: first, the role of descending project...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Lemon RN,Griffiths J

    更新日期:2005-09-01 00:00:00

  • Utility of whole exome sequencing in evaluation of juvenile motor neuron disease.

    abstract:INTRODUCTION:This case report focuses on identifying novel mutations in juvenile motor neuron disease and emphasizes the significance of whole exome sequencing (WES). METHODS:We report a 13-year-old Hispanic boy with rapidly progressive weakness, muscle atrophy, tremor, and tongue fasciculation, along with upper motor...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Agarwal S,Potocki L,Collier TR,Woodbury SL,Adesina AM,Jones J,Lotze TE

    更新日期:2016-04-01 00:00:00

  • Genetic disorders of neuromuscular ion channels.

    abstract::Ion channels are complex proteins that span the lipid bilayer of the cell membrane, where they orchestrate the electrical signals necessary for normal function of the central nervous system, peripheral nerve, and both skeletal and cardiac muscle. The role of ion channel defects in the pathogenesis of numerous disorder...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Kleopa KA,Barchi RL

    更新日期:2002-09-01 00:00:00

  • Ultrasonography of sciatic nerve endometriosis.

    abstract:INTRODUCTION:We describe the ultrasonographic findings of sciatic nerve endometriosis. METHODS:Two premenopausal women with catamenial sciatica symptoms were examined, the first without a history of endometriosis, the second with previously confirmed endometriosis of the ovary. Ultrasonography, extending from the scia...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Arányi Z,Polyák I,Tóth N,Vermes G,Göcsei Z

    更新日期:2016-09-01 00:00:00

  • Motor function-muscle strength relationship in spinal muscular atrophy.

    abstract::The relationship between motor function and muscle strength in patients with spinal muscular atrophy (SMA) is still controversial. In 120 genetically proven SMA patients, aged 5 years or older, we measured muscle strength in the arms and legs by a hand-held dynamometer, forced vital capacity by a spirometer, and the t...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Merlini L,Bertini E,Minetti C,Mongini T,Morandi L,Angelini C,Vita G

    更新日期:2004-04-01 00:00:00

  • Visualization of the diaphragm muscle with ultrasound improves diagnostic accuracy of phrenic nerve conduction studies.

    abstract:INTRODUCTION:Evaluation of phrenic neuropathy (PN) with phrenic nerve conduction studies (PNCS) is associated with false negatives. Visualization of diaphragmatic muscle twitch with diaphragm ultrasound (DUS) when performing PNCS may help to solve this problem. METHODS:We performed bilateral, simultaneous DUS-PNCS in ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Johnson NE,Utz M,Patrick E,Rheinwald N,Downs M,Dilek N,Dogra V,Logigian EL

    更新日期:2014-05-01 00:00:00

  • Medial femoral cutaneous nerve conduction study with distal recording: A novel technique.

    abstract:BACKGROUND:A new technique to obtain the sensory nerve action potential (SNAP) of the medial femoral cutaneous nerve is described. METHODS:SNAPs were recorded from 104 subjects with a bar recording electrode 10 cm proximal to the patella along an imaginary line drawn between the medial edge of the patella and the femo...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Geney-Castro DE,Vanegas-Muñóz J,Plata-Contreras J,Salinas-Duran F

    更新日期:2020-03-01 00:00:00

  • Experimental muscle pain does not cause long-lasting increases in resting electromyographic activity.

    abstract::The mutual links between muscle pain and resting electromyographic (EMG) activity are still controversial. This study described effects of experimental muscle pain on resting EMG activity in a jaw-closing muscle and a leg muscle. Pain was induced by injections of hypertonic saline into the muscles in 10 subjects. Inje...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Svensson P,Graven-Nielsen T,Matre D,Arendt-Nielsen L

    更新日期:1998-11-01 00:00:00

  • Did giant mitochondria delay muscle maturation? An uncommon congenital myopathy.

    abstract:INTRODUCTION:Mitochondria are semi-autonomous organelles that are able to change their shape, size, location, and number inside the living cell. Mitochondrial division is an extremely important process, because cell survival depends on there being an adequate number of mitochondria in each cell. The dynamics of these o...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Fidziańska A,Glinka Z

    更新日期:2012-07-01 00:00:00

  • Clinical and prognostic features in unilateral femoral neuropathies.

    abstract::We have examined the clinical features of patients with femoral neuropathy and the factors that influence the prognosis. Of 80 consecutive patients referred for neurophysiological evaluations of proximal lower limb weakness, 32 fulfilled strict inclusion criteria and had adequate information, including estimates of ax...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Kuntzer T,van Melle G,Regli F

    更新日期:1997-02-01 00:00:00