Turns-amplitude analysis in normal and myopathic facial muscles.


:The purpose of this study was to assess turns/amplitude analysis (TAA) as an objective alternative to conventional qualitative electromyography (EMG) for detection of myopathy in facial muscles. Normal values of TAA parameters were calculated in the frontalis and mentalis muscles of 26 control subjects. We estimated the slope of the regression line of mean amplitude/turn values (MA) plotted against the number of turns/second (NT) and the resulting clouds. The 95% confidence limits of the cloud data were drawn as an ellipse. The sensitivity of TAA was determined from a group of 35 myopathic patients and specificity from a second group of 25 control subjects. Significant differences for every TAA parameter were found between frontalis and mentalis. Cumulative sensitivity and specificity of TAA for frontalis and mentalis were 74.6%, 56.5%, and 73.3%, 70.8%, respectively. With at least two of the aforementioned criteria abnormal, the sensitivity and specificity for frontalis and mentalis were 61.3%, 82.6%, and 56.7%, 100.0%, respectively.


Muscle Nerve


Muscle & nerve


Karandreas N,Kararizou E,Papagianni A,Zambelis T,Kokotis P




Has Abstract


2011-03-01 00:00:00












  • AAEM minimonograph #16: instrumentation and measurement in electrodiagnostic medicine--Part I.

    abstract::Technical and instrumentation factors play an important role in obtaining reliable information during electrodiagnostic studies. With contemporary electrodiagnostic equipment, neurophysiologic potentials are detected using a variety of electrodes and undergo differential amplification, filtering, conversion to digital...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Gitter AJ,Stolov WC

    更新日期:1995-08-01 00:00:00

  • Proteins of muscle subcellular fractions in Duchenne progressive muscular dystrophy stained with "stains-all" cationic carbocyanine dye and with Coomassie Blue.

    abstract::The protein compositions of subcellular fractions of muscle obtained from 17 Duchenne dystrophy patients, 15 disease controls (10 different primary myopathies, 5 spinal muscular atrophy patients), and 10 normals were examined by polyacrylamide gel electrophoresis. The gels were stained with Coomassie Brilliant Blue an...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Niebroj-Dobosz I,Kornguth S,Schutta H,Siegel FL,Hausmanowa-Petrusewicz I

    更新日期:1989-04-01 00:00:00

  • Association between muscle architecture and quadriceps femoris H-reflex.

    abstract::The purpose of the present study was to establish the relationship between muscle architecture and H-reflex recordings in quadriceps femoris muscle. H-reflexes were elicited in human quadriceps femoris muscle over a broad area of skin to document the shape and amplitude of the H-potentials. This, in combination with r...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Garland SJ,Gerilovsky L,Enoka RM

    更新日期:1994-06-01 00:00:00

  • Nerve conduction abnormalities in aging mice deficient for myelin-associated glycoprotein.

    abstract::Ultrastructural, biochemical, and electrophysiological analyses were done on 12-14-month-old mice deficient for myelin-associated glycoprotein (MAG) to further characterize the neuropathy that develops as they age. Electron microscopy demonstrated normal myelin compaction and axonal degeneration in a large number of m...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Weiss MD,Luciano CA,Quarles RH

    更新日期:2001-10-01 00:00:00

  • Sensory physiology assessed by evoked potentials in survivors of poliomyelitis.

    abstract::Evidence suggests that sensory loss may occur in a proportion of patients affected by poliomyelitis. We hypothesize that sensory problems may be a lasting sequela in some polio survivors. Sensory pathways in polio survivors were evaluated clinically and electrophysiologically using sensory evoked potentials (SEPs). Pa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Prokhorenko OA,Vasconcelos OM,Lupu VD,Campbell WW,Jabbari B

    更新日期:2008-10-01 00:00:00

  • Informed consent.

    abstract::Physicians have an ethical and legal duty to obtain patients' informed consent before ordering testing and treatment. Informed consent encompasses informed refusal, the correlative right of patients to refuse tests and therapies they do not want. A patient's informed consent requires adequate information, capacity to ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Bernat JL

    更新日期:2001-05-01 00:00:00

  • Early prednisone treatment in Duchenne muscular dystrophy.

    abstract::The purpose of this long-term, open parallel-group, double-consent study of alternate-day, low-dose prednisone in 2-4-year-old patients with Duchenne muscular dystrophy (DMD) was to determine whether prednisone produces a beneficial effect when given earlier than usual. Muscle function was evaluated by timed tests, an...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章


    authors: Merlini L,Cicognani A,Malaspina E,Gennari M,Gnudi S,Talim B,Franzoni E

    更新日期:2003-02-01 00:00:00

  • Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study.

    abstract::In spite of extensive studies it is unclear whether impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), i.e., impaired glucose metabolism (IGM), causes diabetic sensorimotor polyneuropathy (DSPN) or chronic idiopathic axonal polyneuropathy (CIAP); the results and conclusions vary considerably in differ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Dyck PJ,Dyck PJ,Klein CJ,Weigand SD

    更新日期:2007-10-01 00:00:00

  • Prognostic factors in carpal tunnel syndrome treated with a corticosteroid injection.

    abstract:INTRODUCTION:Symptoms often return in patients with carpal tunnel syndrome (CTS) who are treated with a local corticosteroid injection. We aimed to determine prognostic factors for a successful long-term outcome. METHODS:We prospectively followed 113 patients who received an injection for CTS. Clinical, electrophysiol...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Meys V,Thissen S,Rozeman S,Beekman R

    更新日期:2011-11-01 00:00:00

  • Intercostal Neurolysis for The Treatment of Postsurgical Thoracic Pain: a Case Series.

    abstract:INTRODUCTION:We investigated the possible role of intercostal surgical neurolysis in relieving chronic neuropathic pain refractory to other nonsurgical treatments in patients with postsurgical thoracic pain. METHODS:We retrospectively collected clinical data on patients referred to the Neurosurgery Unit of Policlinic ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Cappellari AM,Tiberio F,Alicandro G,Spagnoli D,Grimoldi N

    更新日期:2018-11-01 00:00:00

  • Chronic nerve compression alters Schwann cell myelin architecture in a murine model.

    abstract:INTRODUCTION:Myelinating Schwann cells compartmentalize their outermost layer to form actin-rich channels known as Cajal bands. Herein we investigate changes in Schwann cell architecture and cytoplasmic morphology in a novel mouse model of carpal tunnel syndrome. METHODS:Chronic nerve compression (CNC) injury was crea...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Gupta R,Nassiri N,Hazel A,Bathen M,Mozaffar T

    更新日期:2012-02-01 00:00:00

  • Further observations on forearm flexor weakness in inclusion body myositis.

    abstract::In order to further characterize and provide a possible mechanism for the asymmetrical involvement of forearm muscles in inclusion body myositis (IBM), we measured isometric hand and pinch grip strength, and forearm muscle girth on 15 IBM patients. Forearm muscle strength and girth were significantly greater on the do...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Felice KJ,Relva GM,Conway SR

    更新日期:1998-05-01 00:00:00

  • Basic polyaminoacids and protamine stimulate enzyme release from frog muscles.

    abstract::Polylysines, polyornithine, and protamine increased the release of creatine kinase (CK) and lactate dehydrogenase (LDH) from frog muscles. With 5 micrograms/ml (50 nM) of a polylysine of molecular weight 100,000, enzyme release reached peak values (ten-fold above control) within 30 minutes; subsequent removal of the p...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Suarez-Kurtz G

    更新日期:1985-02-01 00:00:00

  • Skeletal muscle expression of clathrin and mannose 6-phosphate receptor in experimental chloroquine-induced myopathy.

    abstract::Previous studies suggest that the muscle fiber lysosome system plays a central role in the increased formation of autophagosomes and autolysosomes that occurs in the context of chloroquine-induced myopathy. The goal of this study was to characterize the contribution of receptor-mediated intracellular transport, partic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Masuda T,Ueyama H,Nakamura K,Jikumaru M,Toyoshima I,Kumamoto T

    更新日期:2005-04-01 00:00:00

  • Confocal analysis of the dystrophin protein complex in muscular dystrophy.

    abstract::The dystrophin protein complex (DPC), composed of at least 10 proteins that associate with dystrophin, is critical for the maintenance of normal muscle fiber structure and physiology. In this study, we used immunohistochemistry and confocal microscopy to examine the relative abundance and distribution of several of th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Draviam R,Billington L,Senchak A,Hoffman EP,Watkins SC

    更新日期:2001-02-01 00:00:00

  • Impact of expiratory strength training in amyotrophic lateral sclerosis: Results of a randomized, sham-controlled trial.

    abstract:INTRODUCTION:The purpose of this study was to determine the impact of an in-home expiratory muscle strength training (EMST) program on pulmonary, swallow, and cough function in individuals with amyotrophic lateral sclerosis (ALS). METHODS:EMST was tested in a prospective, single-center, double-blind, randomized, contr...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,随机对照试验


    authors: Plowman EK,Tabor-Gray L,Rosado KM,Vasilopoulos T,Robison R,Chapin JL,Gaziano J,Vu T,Gooch C

    更新日期:2019-01-01 00:00:00

  • Abnormalities of axonal excitability are not generalized in early multifocal motor neuropathy.

    abstract::The clinical and neurophysiological features of multifocal motor neuropathy (MMN) indicate selective involvement of motor axons, but pathological abnormalities in sensory axons suggest a more widespread disease process. The present study was undertaken to determine whether the focal abnormalities are associated with w...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Cappelen-Smith C,Kuwabara S,Lin CS,Burke D

    更新日期:2002-12-01 00:00:00

  • Motor involvement in acute herpes zoster.

    abstract::Motor involvement in acute herpes zoster is considered rare, but its incidence is unknown. In a sample of 40 patients with acute herpes zoster of varying severity, an abnormal electromyogram (EMG) (fibrillation, positive waves, high-frequency discharges) was found in 21 (53%), suggesting extension of inflammation to t...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Haanpää M,Häkkinen V,Nurmikko T

    更新日期:1997-11-01 00:00:00

  • Amyotrophic lateral sclerosis-Evolutionary and other perspectives.

    abstract::In this study some particular and puzzling aspects of amyotrophic lateral sclerosis (ALS) are discussed, with an emphasis on the role of neocortical evolution. Other issues explored include the nature of the clinical deficit in ALS; anatomical and evolutionary aspects of the neocortex, motor cortex, and corpus callosu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Eisen A

    更新日期:2009-08-01 00:00:00

  • Spontaneous and evoked ectopic discharges recorded from single human axons.

    abstract::A quantitative assessment was made of the firing characteristics of repetitive axonal discharges encountered during microneurographic recordings from human peripheral nerves. Spontaneous activity was recorded from 16 single axons using tungsten microelectrodes inserted percutaneously into fascicles of the median or pe...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Macefield VG

    更新日期:1998-04-01 00:00:00

  • Failure to detect HTLV-I by in situ hybridization in the biopsied muscles of viral carriers with polymyositis.

    abstract::Direct infection of muscle fibers by human T-lymphotropic virus type I (HTLV-I) has recently been reported in a patient with polymyositis infected with both HTLV-I and human immunodeficiency virus (HIV). Coinfections of these viruses are frequently found in the United States. In Kagoshima, Japan, patients with polymyo...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Higuchi I,Nerenberg M,Yoshimine K,Yoshida M,Fukunaga H,Tajima K,Osame M

    更新日期:1992-01-01 00:00:00

  • Multiple forms of anti-acetylcholine receptor antibody in myasthenia gravis.

    abstract::Sera of patients with myasthenia gravis (MG) contain anti-acetylcholine receptor (AChR) IgG antibodies (Ab) which have different antigenic specificities. Three Ab types were detected: (1) MG-I, which forms immune complexes with AChR; (2) MG-C, which decreases binding of AChR to concanavalin A; and MG-B, which blocks a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Mittag T,Massa T,Kornfeld P,Papatestas A,Bender A,Genkins G

    更新日期:1981-01-01 00:00:00

  • Recommendations for myasthenia gravis clinical trials.

    abstract::The recommendations for clinical research standards published in 2000 by a task force of the Medical Scientific Advisory Board (MSAB) of the Myasthenia Gravis Foundation of America (MGFA) were largely successful in introducing greater uniformity in the recording and reporting of MG clinical trials. Recognizing that ch...

    journal_title:Muscle & nerve

    pub_type: 共识发展会议,杂志文章


    authors: Benatar M,Sanders DB,Burns TM,Cutter GR,Guptill JT,Baggi F,Kaminski HJ,Mantegazza R,Meriggioli MN,Quan J,Wolfe GI,Task Force on MG Study Design of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America

    更新日期:2012-06-01 00:00:00

  • Assessment of aged mdx mice by electrical impedance myography and magnetic resonance imaging.

    abstract:INTRODUCTION:Similar to magnetic resonance imaging (MRI), electrical impedance myography (EIM) is dependent on the presence and location of water in muscle to assess neuromuscular diseases. We compared the 2 technologies in mdx mice to better understand their relationship. METHODS:EIM and MRI, using T2 relaxation and ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Wu JS,Li J,Greenman RL,Bennett D,Geisbush T,Rutkove SB

    更新日期:2015-10-01 00:00:00

  • Response to therapy in demyelinating motor neuropathy.

    abstract::We reviewed results of immunotherapy in patients with demyelinating motor neuropathy (DMN), and found that patients over 50 years of age at onset responded poorly, and younger patients responded variably to intervention. We suggest that patients with DMN be given a guarded prognosis, particularly if >50 years of age a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Markson L,Janzen D,Bril V

    更新日期:1998-12-01 00:00:00

  • Iron load and redox stress in skeletal muscle of aged rats.

    abstract::Loss of skeletal muscle mass (sarcopenia) is a major contributor to disability in old age. We used two-dimensional gel electrophoresis and mass spectrometry to screen for changes in proteins, and cDNA profiling to assess transcriptional regulations in the gastrocnemius muscle of adult (4 months) and aged (30 months) m...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Altun M,Edström E,Spooner E,Flores-Moralez A,Bergman E,Tollet-Egnell P,Norstedt G,Kessler BM,Ulfhake B

    更新日期:2007-08-01 00:00:00

  • Novel mutations in the gene encoding very long-chain acyl-CoA dehydrogenase identified in patients with partial carnitine palmitoyltransferase II deficiency.

    abstract:INTRODUCTION:Twenty-six patients with clinical symptoms of adult onset carnitine palmitoyltransferase II (CPTII) deficiency were examined. All patients had skeletal muscle CPTII enzyme activity levels indicative of heterozygosity for CPT2 mutations, however sequence analysis identified no pathogenic mutations within th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Isackson PJ,Sutton KA,Hostetler KY,Vladutiu GD

    更新日期:2013-02-01 00:00:00

  • Electrophysiologic findings and grip strength after nerve injuries in the rat forelimb.

    abstract::We developed electrophysiologic methods for testing the three major forelimb nerves as a tool to evaluate motor and sensory recovery in rats. Median, ulnar, or radial nerves were transected and repaired in Sprague-Dawley rats. Compound muscle action potentials (CMAPs) and somatosensory evoked potentials (SSEPs) were r...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Wang H,Sorenson EJ,Spinner RJ,Windebank AJ

    更新日期:2008-10-01 00:00:00

  • Utility of whole exome sequencing in evaluation of juvenile motor neuron disease.

    abstract:INTRODUCTION:This case report focuses on identifying novel mutations in juvenile motor neuron disease and emphasizes the significance of whole exome sequencing (WES). METHODS:We report a 13-year-old Hispanic boy with rapidly progressive weakness, muscle atrophy, tremor, and tongue fasciculation, along with upper motor...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Agarwal S,Potocki L,Collier TR,Woodbury SL,Adesina AM,Jones J,Lotze TE

    更新日期:2016-04-01 00:00:00

  • Utility of multi-channel surface electromyography in assessment of focal hand dystonia.

    abstract:INTRODUCTION:Surface electromyography (SEMG) allows objective assessment and guides selection of appropriate treatment in focal hand dystonia (FHD). METHODS:Sixteen-channel SEMG obtained during different phases of a writing task was used to study timing, activation patterns, and spread of muscle contractions in FHD co...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Sivadasan A,Sanjay M,Alexander M,Devasahayam SR,Srinivasa BK

    更新日期:2013-09-01 00:00:00