The utility of a point-of-care sural nerve conduction device for detection of diabetic polyneuropathy: A cross-sectional study.

Abstract:

INTRODUCTION:Rapid and accessible methods for diagnosing diabetic polyneuropathy (DPN) have been developed, but not validated, in large cohorts of people with diabetes. METHODS:The performance of a point-of-care device (POCD) was studied in 168 patients with type 2 diabetes, estimating the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) compared with conventional sural nerve conduction studies (NCS). RESULTS:A POCD amplitude limit of 6 µV increased the sensitivity (96%) and NPV (98%), but decreased the specificity (71%) and PPV (54%) compared with the 4-µV limit, which had values of 78%, 92%, 89%, and 71%, respectively. POCD on both legs showed better performance than on 1 leg. POCD amplitudes and conduction velocities correlated significantly with conventional sural NCS, but POCD values were underestimated compared with NCS. DISCUSSION:The POCD may be used as a suitable screening tool for detection of DPN. Patients with abnormal and borderline results should undergo conventional NCS. Muscle Nerve 59:187-193, 2019.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Kural MA,Andersen ST,Andersen NT,Andersen H,Charles M,Finnerup NB,Jensen TS,Tankisi H

doi

10.1002/mus.26361

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

187-193

issue

2

eissn

0148-639X

issn

1097-4598

journal_volume

59

pub_type

杂志文章
  • Modulation of muscle activity and force fluctuations in the plantarflexors after bedrest depends on knee position.

    abstract::Force fluctuations in leg muscles increase after bedrest, perhaps due to modulation of the neural strategy that is specific to a muscle or common to agonist muscles. The purpose of this study was to examine the modulation of muscle activity and force fluctuations during steady contractions with variable involvement of...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20764

    authors: Yoshitake Y,Kouzaki M,Fukuoka H,Fukunaga T,Shinohara M

    更新日期:2007-06-01 00:00:00

  • Continuous motor unit activity confined to the upper extremities.

    abstract::We report a patient with clinical vermiform motor activity, muscle cramps, delayed relaxation of grip, and continuous motor unit discharges who developed mild symmetric symptoms in the upper extremities following a viral infection. Treatment with carbamazepine produced considerable symptomatic improvement. Needle elec...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110310

    authors: Tandan R,Fries TJ

    更新日期:1988-03-01 00:00:00

  • Somatosensory evoked potentials of the medial and lateral plantar and calcaneal nerves.

    abstract::The ideal electrodiagnostic procedure to assess possible plantar neuropathies continues to elude investigators. Motor studies are rarely abnormal, pure sensory studies may be difficult to obtain, needle electromyography can demonstrate membrane instability in normal feet. Mixed nerve plantar studies may be more diagno...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880140710

    authors: Dumitru D,Kalantri A,Dierschke B

    更新日期:1991-07-01 00:00:00

  • Myasthenia gravis: a personal view of pathogenesis and mechanism, part 1.

    abstract::A review of our current knowledge of the etiology and pathogenesis of myasthenia gravis is presented, with particular emphasis on the immunological aspects of the disease. Part 1, published in this issue, deals with the clinical and genetic features of myasthenia gravis which led to the autoimmune theory of the etiolo...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.880010107

    authors: Simpson JA

    更新日期:1978-01-01 00:00:00

  • Calpain 3 cleaves filamin C and regulates its ability to interact with gamma- and delta-sarcoglycans.

    abstract::Calpain 3 (C3) is the only muscle-specific member of the calcium-dependent protease family. Although neither its physiological function nor its in vivo substrates are known, C3 must be an important protein for normal muscle function as mutations in the C3 gene result in limb-girdle muscular dystrophy type 2A. Previous...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.10465

    authors: Guyon JR,Kudryashova E,Potts A,Dalkilic I,Brosius MA,Thompson TG,Beckmann JS,Kunkel LM,Spencer MJ

    更新日期:2003-10-01 00:00:00

  • Postpolio muscular dysfunction: relationships between muscle energy metabolism, subjective symptoms, magnetic resonance imaging, electromyography, and muscle strength.

    abstract::Eleven patients with previous polio were studied. The concentration of energy-related metabolites and energy charge was measured from the vastus lateralis muscle, as was isometric muscle strength of knee extension. Cross-sectional area of the quadriceps femoris muscle was calculated from magnetic resonance imaging. Re...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199711)20:11<1341::aid-mus

    authors: Nordgren B,Falck B,Stålberg E,Ronquist G,Waldenström A,Ahlström H,Hemmingson A

    更新日期:1997-11-01 00:00:00

  • Application of differentiated human tonsil-derived stem cells to trembler-J mice.

    abstract:INTRODUCTION:Mesenchymal stem cells (MSCs) can differentiate into various cell types. METHODS:In this study we investigated the potential of human tonsil-derived MSCs (T-MSCs) for neuromuscular regeneration in trembler-J (Tr-J) mice, a model for Charcot-Marie-Tooth disease type 1A (CMT1A). RESULTS:T-MSCs differentiat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25763

    authors: Park S,Choi Y,Kwak G,Hong YB,Jung N,Kim J,Choi BO,Jung SC

    更新日期:2018-03-01 00:00:00

  • Physiological cross-sectional area of the oblique head of the adductor pollicis is greater than its transverse counterpart: implications for functional testing.

    abstract:INTRODUCTION:Despite structural distinction between the transverse and oblique heads of the adductor pollicis, in vivo testing continues to consider the adductor pollicis as functionally simplistic. As a muscle's architecture is a strong indicator of function, in this study we aimed to determine whether the physiologic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23933

    authors: Stamenkovic A,Munro BJ,Peoples GE

    更新日期:2014-03-01 00:00:00

  • Spontaneous and evoked ectopic discharges recorded from single human axons.

    abstract::A quantitative assessment was made of the firing characteristics of repetitive axonal discharges encountered during microneurographic recordings from human peripheral nerves. Spontaneous activity was recorded from 16 single axons using tungsten microelectrodes inserted percutaneously into fascicles of the median or pe...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199804)21:4<461::aid-mus4>

    authors: Macefield VG

    更新日期:1998-04-01 00:00:00

  • Benign course of glycogen storage disease type IIb in two brothers: nature or nurture?

    abstract::Two brothers with the childhood variant of type II glycogenosis (GSD-IIb) treated with nutrition and exercise therapy (NET) from a young age showed an unusually benign course. Muscle biopsy from the older brother, which showed characteristic vacuolar glycogen accumulation at age 2, had reverted to normal by age 16. A ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20473

    authors: Slonim AE,Bulone L,Minikes J,Hays AP,Shanske S,Tsujino S,DiMauro S

    更新日期:2006-04-01 00:00:00

  • Electrodiagnostic errors contribute to chronic inflammatory demyelinating polyneuropathy misdiagnosis.

    abstract:INTRODUCTION:Documentation of peripheral nerve demyelination is an important part of the chronic inflammatory demyelinating polyneuropathy (CIDP) diagnostic process. METHODS:We performed a retrospective analysis of patients referred with a diagnosis of CIDP who were found to have a different condition. Electrodiagnost...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25997

    authors: Allen JA,Ney J,Lewis RA

    更新日期:2018-04-01 00:00:00

  • Chronic nerve compression alters Schwann cell myelin architecture in a murine model.

    abstract:INTRODUCTION:Myelinating Schwann cells compartmentalize their outermost layer to form actin-rich channels known as Cajal bands. Herein we investigate changes in Schwann cell architecture and cytoplasmic morphology in a novel mouse model of carpal tunnel syndrome. METHODS:Chronic nerve compression (CNC) injury was crea...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22276

    authors: Gupta R,Nassiri N,Hazel A,Bathen M,Mozaffar T

    更新日期:2012-02-01 00:00:00

  • Myasthenia gravis associated with HTLV-I infection and atypical brain lesions.

    abstract::We report a patient who experienced progressive diplopia and distal weakness of the upper limbs. Magnetic resonance imaging of the brain showed extensive white matter lesions and analysis of cerebrospinal fluid revealed acute human T-lymphotropic virus type I (HTLV-I) infection. Myasthenia gravis (MG) was evidenced by...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20694

    authors: Lalive PH,Allali G,Truffert A

    更新日期:2007-04-01 00:00:00

  • Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes.

    abstract:INTRODUCTION:In this study we sought to determine the cross-sectional area (CSA) of peripheral nerves in patients with distinct subtypes of amyotrophic lateral sclerosis (ALS). METHODS:Ulnar and median nerve ultrasound was performed in 78 ALS patients [classic, n = 21; upper motor neuron dominant (UMND), n = 14; lower...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24431

    authors: Schreiber S,Abdulla S,Debska-Vielhaber G,Machts J,Dannhardt-Stieger V,Feistner H,Oldag A,Goertler M,Petri S,Kollewe K,Kropf S,Schreiber F,Heinze HJ,Dengler R,Nestor PJ,Vielhaber S

    更新日期:2015-05-01 00:00:00

  • Effect of gender and obesity on electrical current thresholds.

    abstract:INTRODUCTION:In this study we investigated the influence of gender and obesity on electrical current thresholds in an attempt to optimize the application of skeletal muscle electrical stimulation (ES) in clinical practice. METHODS:Thirty-two obese and 35 age-matched, non-obese men and women received graded ES to the q...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22050

    authors: Maffiuletti NA,Morelli A,Martin A,Duclay J,Billot M,Jubeau M,Agosti F,Sartorio A

    更新日期:2011-08-01 00:00:00

  • Hospitalizations and emergency room visits for adolescents and young adults with muscular dystrophy living in South Carolina.

    abstract:INTRODUCTION:Transitioning from adolescence to adulthood can be problematic for individuals with rare disabilities such as muscular dystrophy (MD). METHODS:We identified a cohort of 220 individuals with MD and 440 matched comparison individuals and measured emergency room (ER) and inpatient (IP) encounters for the yea...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24599

    authors: Mann JR,Royer JA,Mcdermott S,Hardin JW,Ozturk O,Street N

    更新日期:2015-11-01 00:00:00

  • The physiological basis of conduction slowing in ALS patients homozygous for the D90A CuZn-SOD mutation.

    abstract::Familial amyotrophic lateral sclerosis (ALS) with the autosomal-recessively inherited D90A CuZn-superoxide dismutase (CuZn-SOD) mutation is characterized by a stereotypic slowly progressive, distinctive phenotype and very slow central motor conduction. To determine the basis of this slowing, we assessed corticomotoneu...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-4598(200101)24:1<89::aid-mus10>3.0.co

    authors: Weber M,Eisen A,Stewart HG,Andersen PM,Hirota N

    更新日期:2001-01-01 00:00:00

  • Congenital cervical spinal atrophy.

    abstract::Three children presented at birth with axial hypotonia and symmetrical flaccid paresis limited to the upper extremities, and involving proximal and distal muscle groups. At birth, palmar flexion creases were poorly developed, and the hand muscles were atrophic. These clinical features, the muscle biopsy findings, and ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880040205

    authors: Darwish H,Sarnat H,Archer C,Brownell K,Kotagal S

    更新日期:1981-03-01 00:00:00

  • Analysis of muscle fiber clustering in the diaphragm muscle of sarcopenic mice.

    abstract:INTRODUCTION:Sarcopenia likely comprises muscle fiber denervation and re-innervation, resulting in clustering of muscle fibers of the same type (classified by myosin heavy chain isoform composition). Development of methodology to quantitatively evaluate clustering of muscle fibers according to fiber type is necessary. ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24641

    authors: Greising SM,Medina-Martínez JS,Vasdev AK,Sieck GC,Mantilla CB

    更新日期:2015-07-01 00:00:00

  • Premotor potential study in carpal tunnel syndrome.

    abstract:INTRODUCTION:Premotor potentials (PMPs) precede compound muscle action potentials evoked from the second lumbrical muscle after median nerve stimulation. Although PMP has been identified as a median sensory nerve action potential, few reports have documented the significance of PMP parameters for diagnosing carpal tunn...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23424

    authors: Kodama M,Sasao Y,Tochikura M,Kasahara T,Koyama Y,Aono K,Fujii C,Hanayama K,Takahashi O,Kobayashi Y,Masakado Y

    更新日期:2012-12-01 00:00:00

  • Body weight-supported training in Becker and limb girdle 2I muscular dystrophy.

    abstract:INTRODUCTION:We studied the functional effects of combined strength and aerobic anti-gravity training in severely affected patients with Becker and Limb-Girdle muscular dystrophies. METHODS:Eight patients performed 10-week progressive combined strength (squats, calf raises, lunges) and aerobic (walk/run, jogging in pl...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25039

    authors: Jensen BR,Berthelsen MP,Husu E,Christensen SB,Prahm KP,Vissing J

    更新日期:2016-08-01 00:00:00

  • Nerve conduction studies in amyotrophic lateral sclerosis.

    abstract::We studied 137 ulnar nerves and abductor digiti minimi (ADM) muscles in 70 patients with amyotrophic lateral sclerosis (ALS), and correlated the results with ADM strength graded on the Medical Research Council (MRC) scale, to address the potential value of a standardized neurophysiological assessment of this nerve-mus...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(200003)23:3<344::aid-mus5>

    authors: de Carvalho M,Swash M

    更新日期:2000-03-01 00:00:00

  • Immunohistochemical characterization of human masseter muscle spindles.

    abstract::An enzyme- and immunohistochemical study has been performed on human masseter muscle spindles. Antibodies selective for different myosin heavy chain (MHC) isoforms and M-band proteins (M-protein, myomesin, and MM-CK) were used. The expression of these proteins was determined in the different intrafusal fiber types. Nu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880170105

    authors: Eriksson PO,Butler-Browne GS,Thornell LE

    更新日期:1994-01-01 00:00:00

  • Statistical motor unit number estimation: reproducibility and sources of error in patients with amyotrophic lateral sclerosis.

    abstract::The reliability of motor unit number estimation (MUNE) for assessment of the long-term course of ALS is dependent on the reproducibility of the technique. We report our results with the statistical method of MUNE on the ulnar nerve/hypothenar muscle in 16 ALS patients who were studied on 52 occasions. On each occasion...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1097-4598(200002)23:2<193::aid-mus8>

    authors: Olney RK,Yuen EC,Engstrom JW

    更新日期:2000-02-01 00:00:00

  • Update on immune-mediated therapies for myasthenia gravis.

    abstract::With the exception of thymectomy, immune modulatory treatment strategies and clinical trials in myasthenia gravis over the past 50 y were mainly borrowed from experience in other nonneurologic autoimmune disorders. The current experimental therapy paradigm has significantly changed such that treatments directed agains...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.26919

    authors: Habib AA,Ahmadi Jazi G,Mozaffar T

    更新日期:2020-11-01 00:00:00

  • VCP myopathy: A family with unusual clinical manifestations.

    abstract:INTRODUCTION:Valosin-containing protein (VCP) variants that affect muscle, bone, and the nervous system are termed multisystem proteinopathy. VCP myopathy is manifested as limb-girdle weakness, distal weakness and scapuloperoneal weakness. METHODS:We reviewed clinical, genetic, and muscle biopsy data from 6 members of...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26389

    authors: Guo X,Zhao Z,Shen H,Qi B,Li N,Hu J

    更新日期:2019-03-01 00:00:00

  • Demyelinating neuropathy with anti-CRMP5 antibodies predating diagnosis of breast carcinoma: favorable outcome after cancer therapy.

    abstract:INTRODUCTION:Breast cancer is exceptionally associated with anti-collapsin response mediator protein 5 (anti-CRMP5) antibody or demyelinating neuropathy. This paraneoplastic antibody is itself not associated with demyelinating neuropathy. METHODS:Herein we describe a patient with a predominantly sensory ataxic demyeli...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22036

    authors: Samarasekera S,Rajabally YA

    更新日期:2011-05-01 00:00:00

  • Differential diagnosis of chronic dysimmune demyelinating polyneuropathies with and without anti-MAG antibodies.

    abstract::The distinction between chronic demyelinating polyneuropathies associated with IgM paraproteinemia and anti-myelin-associated glycoprotein (MAG) antibodies (MAG-PN) and chronic inflammatory demyelinating polyneuropathies (CIDPs) relies on the anti-MAG antibodies assay. The aim of the study was to identify clinical and...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20230

    authors: Isoardo G,Migliaretti G,Ciaramitaro P,Rota E,Poglio F,Tavella A,Paolasso I,Cavallo F,Bergamasco B,Cocito D

    更新日期:2005-01-01 00:00:00

  • Bone density and alendronate effects in Duchenne muscular dystrophy patients.

    abstract:INTRODUCTION:Patients with DMD have low bone mineral density (BMD) and are at high risk for fractures. We examined changes in BMD and the effects of alendronate in DMD patients treated at our institution in the last decade. METHODS:Retrospective cohort study of 39 DMD patients. RESULTS:Patients had screening dual ene...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23948

    authors: Houston C,Mathews K,Shibli-Rahhal A

    更新日期:2014-04-01 00:00:00

  • Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves.

    abstract::It is important to know the effects of prolonged repetitive nerve stimulation (RNS) when it is used in neurophysiological studies. RNS with up to 100 supramaximal stimuli was given to the median, ulnar, and peroneal nerves of normal subjects and the ulnar nerves of subjects with early amyotrophic lateral sclerosis (AL...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21604

    authors: Baumann F,Henderson RD,Tremayne F,Hutchinson N,McCombe PA

    更新日期:2010-06-01 00:00:00