Abstract:
:A review of our current knowledge of the etiology and pathogenesis of myasthenia gravis is presented, with particular emphasis on the immunological aspects of the disease. Part 1, published in this issue, deals with the clinical and genetic features of myasthenia gravis which led to the autoimmune theory of the etiology of this disease. Various theories in this field are reviewed, and recent advances in our knowledge of the acetylcholine receptor protein, and its immunology, are examined. Part 2, which will appear in the March/April issue, provides a review of the dysfunction of physiology, pharmacology, and structure of the neuromuscular junction in myasthenia gravis, and the part played by the autoimmune process.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Simpson JAdoi
10.1002/mus.880010107subject
Has Abstractpub_date
1978-01-01 00:00:00pages
45-56issue
1eissn
0148-639Xissn
1097-4598journal_volume
1pub_type
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