Focal inflammatory myopathy.

Abstract:

:We report three patients with inflammatory myopathy who presented clinically with weakness and wasting of only one limb. The myopathy progressed over 6 months and 5 years, respectively, in two patients and was stable after 8 years in the third patient. One patient had a skin rash. Serum CK was elevated in the two patients with progressive disease. Electromyography showed brief duration, small amplitude motor unit potentials and fibrillations in the affected limbs. Muscle biopsy revealed variable fiber size, degenerating and regenerating fibers, and inflammatory foci. Vasculitis was seen in the patient with skin lesions and marked fibroblastic proliferation in the patient with the most chronic course. Immunosuppressive therapy has arrested the progression in the two patients treated; both have regained strength.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Lederman RJ,Salanga VD,Wilbourn AJ,Hanson MR,Dudley AW Jr

doi

10.1002/mus.880070210

subject

Has Abstract

pub_date

1984-02-01 00:00:00

pages

142-6

issue

2

eissn

0148-639X

issn

1097-4598

journal_volume

7

pub_type

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