Abstract:
:We report three patients with inflammatory myopathy who presented clinically with weakness and wasting of only one limb. The myopathy progressed over 6 months and 5 years, respectively, in two patients and was stable after 8 years in the third patient. One patient had a skin rash. Serum CK was elevated in the two patients with progressive disease. Electromyography showed brief duration, small amplitude motor unit potentials and fibrillations in the affected limbs. Muscle biopsy revealed variable fiber size, degenerating and regenerating fibers, and inflammatory foci. Vasculitis was seen in the patient with skin lesions and marked fibroblastic proliferation in the patient with the most chronic course. Immunosuppressive therapy has arrested the progression in the two patients treated; both have regained strength.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Lederman RJ,Salanga VD,Wilbourn AJ,Hanson MR,Dudley AW Jrdoi
10.1002/mus.880070210subject
Has Abstractpub_date
1984-02-01 00:00:00pages
142-6issue
2eissn
0148-639Xissn
1097-4598journal_volume
7pub_type
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