Endoneurial sodium accumulation in galactosemic rat nerves.

Abstract:

:Microdrop samples of endoneurial fluid and serum from galactosemic rats were analyzed with energy dispersive spectrometry (EDS). The sodium concentration of endoneurial fluid from galactose-fed rats (295 meq/liter) was nearly twice that of age-matched controls (152 meq/liter) and indicates that sodium is present in an osmotically significant concentration that is capable of causing the edema and increased endoneurial fluid pressure (EFP) associated with galactose neuropathy. It is suggested that accumulation of endoneurial sodium is linked to the movement of sugar into the endoneurium.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Mizisin AP,Myers RR,Powell HC

doi

10.1002/mus.880090509

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

440-4

issue

5

eissn

0148-639X

issn

1097-4598

journal_volume

9

pub_type

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