The temperature dependence of halothane-induced contractures of skeletal muscle.

abstract：INTRODUCTION:The neuropathy in patients with neurofibromatosis type 2 (NF2) is difficult to quantify and follow up. In this study we compared 3 methods that may help assess motor axon pathology in NF2 patients. METHODS:Nerve conduction studies in median nerves were supplemented by deriving motor unit number estimates ...

journal_title：Muscle & nerve

authors： Farschtschi S,Gelderblom M,Buschbaum S,Bostock H,Grafe P,Mautner VF

更新日期：2017-03-01 00:00:00

abstract：:Case reports and open-label studies suggest that coenzyme Q(10) (CoQ(10)) treatment may have beneficial effects in mitochondrial disease patients; however, controlled trials are warranted to clinically prove its effectiveness. Thirty patients with mitochondrial cytopathy received 1200 mg/day CoQ(10) for 60 days in a r...

journal_title：Muscle & nerve

authors： Glover EI,Martin J,Maher A,Thornhill RE,Moran GR,Tarnopolsky MA

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:A randomized trial demonstrated benefit from thymectomy in nonthymomatous acetylcholine receptor (AChR)-antibody positive myasthenia gravis (MG). Uncontrolled observational and histologic studies suggest thymectomy may not be efficacious in anti-muscle-specific kinase (MuSK)-MG. METHODS:The therapeutic im...

journal_title：Muscle & nerve

authors： Clifford KM,Hobson-Webb LD,Benatar M,Burns TM,Barnett C,Silvestri NJ,Howard JF Jr,Visser A,Crum BA,Nowak R,Beekman R,Kumar A,Ruzhansky K,Chen IA,Pulley MT,Laboy SM,Fellman MA,Howard DB,Kolb NA,Greene SM,Pasnoor M

更新日期：2019-04-01 00:00:00

abstract：:Mechanical deformation of a peripheral nerve can evoke action potentials in sensory and motor axons. The generation of these impulses with brief stimuli (<0.5 s) and their relationship to the deformation conditions have not been systematically studied in human subjects. Controlled compression stimuli over a range of a...

journal_title：Muscle & nerve

authors： Clarke EC,McNulty PA,Macefield VG,Bilston LE

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine the patterns of responses for the electromyographic (EMG) amplitude vs. oxygen uptake ( V̇O2 ) relationships from muscles of the quadriceps femoris and hamstrings during incremental treadmill running. METHODS:Twelve men volunteered to perform an incremental test to e...

journal_title：Muscle & nerve

authors： Camic CL,Kovacs AJ,Enquist EA,McLain TA,Hill EC

更新日期：2015-12-01 00:00:00

abstract：:Hindlimb unloading (HU) results in oxidative stress, skeletal muscle atrophy, and increased damage upon reloading. Heat shock proteins (HSPs) protect against oxidative stress. However, it is unknown whether HSPs are depressed with long-term unloading (28 days) or reloading. We tested the hypotheses that long-term HU w...

journal_title：Muscle & nerve

authors： Lawler JM,Song W,Kwak HB

更新日期：2006-02-01 00:00:00

abstract：:Muscle weakness in myasthenia gravis is due to autoantibody-induced loss of functional acetylcholine receptors (AChR). About 15% of myasthenia gravis patients, however, do not have detectable anti-AChR antibodies. To investigate the effect of their plasma immunoglobulins on neuromuscular transmission, mice were inject...

journal_title：Muscle & nerve

authors： Burges J,Vincent A,Molenaar PC,Newsom-Davis J,Peers C,Wray D

更新日期：1994-12-01 00:00:00

abstract：INTRODUCTION:In this study we assessed the effect of paired stimuli on the latencies and amplitudes of the blink reflex. METHODS:Blink reflexes were performed with single and paired (5-ms interstimulus interval) stimuli in 47 patients. The changes in latencies between paired and single stimuli were calculated. RESULT...

journal_title：Muscle & nerve

authors： Rubin DI,Dimberg EL,Kennelly KD

更新日期：2011-08-01 00:00:00

abstract：:Skeletal muscle involvement can occur at all stages of human immunodeficiency virus (HIV) infection, and may represent the first manifestation of the disease. Myopathies in HIV-infected patients are classified as follows: (1) HIV-associated myopathies and related conditions, including HIV polymyositis, inclusion-body ...

journal_title：Muscle & nerve

authors： Authier FJ,Chariot P,Gherardi RK

更新日期：2005-09-01 00:00:00

abstract：INTRODUCTION:Documentation of peripheral nerve demyelination is an important part of the chronic inflammatory demyelinating polyneuropathy (CIDP) diagnostic process. METHODS:We performed a retrospective analysis of patients referred with a diagnosis of CIDP who were found to have a different condition. Electrodiagnost...

journal_title：Muscle & nerve

authors： Allen JA,Ney J,Lewis RA

更新日期：2018-04-01 00:00:00

abstract：:Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...

journal_title：Muscle & nerve

authors： Pecot-Dechavassine M,Mira JC

更新日期：1985-02-01 00:00:00

abstract：:Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were studied in the diaphragm of early postnatal rats, using radiometric determination of enzyme activities, velocity sedimentation for separation of molecular forms, and electron microscopic cytochemistry to localize enzymes. AChE activity did not change s...

journal_title：Muscle & nerve

authors： Brzin M,Sketelj J,Tennyson VM,Kiauta T,Budininkas-Schoenebeck M

更新日期：1981-11-01 00:00:00

abstract：:Focal myositis is a rare inflammatory pseudotumor of skeletal muscle which usually has a benign course. We report a 56-year-old woman with a painful mass in the left arm with a radial nerve palsy. Magnetic resonance imaging (MRI) of the left arm showed a mass in the triceps muscle that was suggestive of a soft-tissue ...

journal_title：Muscle & nerve

authors： Alzagatiti BI,Bertorini TE,Horner LH,Maccarino VS,O'Brien T

更新日期：1999-07-01 00:00:00

abstract：:The absolute number of satellite cells (SC) in young and adult rat skeletal muscle was estimated by correlating data from light and electron microscopic quantitation of myofiber nuclei (myonuclei and satellite cell nuclei) with biochemical assays for determining total muscle DNA content. Expressed both as a proportion...

journal_title：Muscle & nerve

authors： Gibson MC,Schultz E

更新日期：1983-10-01 00:00:00

abstract：:Calmodulin levels have been assessed in whole muscle and primary culture extracts in order to examine the relationship between calmodulin and the accumulation of calcium in dystrophic hamster muscle tissues. Significant decreases in both normal and dystrophic skeletal muscle, tongue, and heart calmodulin levels were o...

journal_title：Muscle & nerve

authors： Klamut HJ,Kotarba JA,Strickland KP

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:Accuracy of needle electromyography is typically ensured by use of anatomical landmarks and auditory feedback related to voluntary activation of the targeted muscle; however, in certain clinical situations, landmarks may not be palpable, auditory feedback may be limited or not present, and targeting a spec...

journal_title：Muscle & nerve

authors： Boon AJ,Oney-Marlow TM,Murthy NS,Harper CM,McNamara TR,Smith J

更新日期：2011-07-01 00:00:00

abstract：:Injuries to the lumbosacral plexus during labor and delivery have been reported in the literature for years, but have lacked electrophysiologic testing to substantiate the location of the nerve injury. We report 2 cases with comprehensive electrophysiologic testing which localizes the site of this obstetrical paralysi...

journal_title：Muscle & nerve

authors： Feasby TE,Burton SR,Hahn AF

更新日期：1992-08-01 00:00:00

abstract：INTRODUCTION:Nemaline myopathy is a rare disorder characterized by skeletal muscle weakness of varying severity and onset, with the presence of nemaline rods on muscle biopsy. Congenital nemaline body myopathy due to mutations in TNNT1 has hitherto only been described as a result of a single founder mutation in patient...

journal_title：Muscle & nerve

authors： Abdulhaq UN,Daana M,Dor T,Fellig Y,Eylon S,Schuelke M,Shaag A,Elpeleg O,Edvardson S

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:In compressive neuropathies, large myelinated nerve fibers are generally thought to be more susceptible. In this study, we investigated small myelinated Aδ and unmyelinated C fiber function in patients with mild, moderate, and severe carpal tunnel syndrome. METHODS:Forty-four healthy controls and 81 carpa...

journal_title：Muscle & nerve

authors： Clarke C,Christensen C,Curran MWT,Chan KM

更新日期：2017-10-01 00:00:00

abstract：:Several approaches to treat laminin alpha2 chain-deficient congenital muscular dystrophy (MDC1A) in mouse models have been undertaken. Most have shown promising results in young animals. However, older animals have only been characterized to some extent. Herein we analyze the lifespan of laminin alpha2 chain-deficient...

journal_title：Muscle & nerve

authors： Gawlik KI,Durbeej M

更新日期：2010-07-01 00:00:00

abstract：INTRODUCTION:Although formal spirometry is the gold standard for monitoring respiratory function in patients with myasthenia gravis (MG), such testing is often delayed or unavailable. There is a need for a simple bedside test that can accurately measure respiratory function. METHODS:We conducted a prospective, cross-s...

journal_title：Muscle & nerve

authors： Elsheikh B,Arnold WD,Gharibshahi S,Reynolds J,Freimer M,Kissel JT

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:We studied the functional effects of combined strength and aerobic anti-gravity training in severely affected patients with Becker and Limb-Girdle muscular dystrophies. METHODS:Eight patients performed 10-week progressive combined strength (squats, calf raises, lunges) and aerobic (walk/run, jogging in pl...

journal_title：Muscle & nerve

authors： Jensen BR,Berthelsen MP,Husu E,Christensen SB,Prahm KP,Vissing J

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to identify the pattern of neurological deficits and document electrophysiological changes in women with macromastia. METHODS:Patients with macromastia and neurological complaints underwent clinical evaluation and electrodiagnostic (EDx) studies of the upper limbs. RESULTS...

journal_title：Muscle & nerve

authors： Ansell JR,Buchholz MC

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:Hand-held dynamometry (HHD) is commonly used to measure ankle plantarflexion strength but has variable reliability measuring higher forces. Fixed HHD is suggested to improve reliability. We, therefore, compared the reliability, consistency, and accuracy of measuring plantarflexion strength. METHODS:Planta...

journal_title：Muscle & nerve

authors： Davis PR,McKay MJ,Baldwin JN,Burns J,Pareyson D,Rose KJ

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:In mitochondrial disease, it is likely that energy substrate depletion leads to paralysis of ATPase-dependent pumps, resulting in membrane depolarization. Axonal depolarization has been demonstrated in a crisis, but not in the resting state. We, therefore, stressed axons using ischemia to see if this would...

journal_title：Muscle & nerve

authors： Ng K,Kumar KR,Sue C,Burke D

更新日期：2013-05-01 00:00:00

abstract：:The neuromuscular junction (NMJ) is a complex structure that serves to efficiently communicate the electrical impulse from the motor neuron to the skeletal muscle to signal contraction. Over the last 200 years, technological advances in microscopy allowed visualization of the existence of a gap between the motor neuro...

journal_title：Muscle & nerve

authors： Hughes BW,Kusner LL,Kaminski HJ

更新日期：2006-04-01 00:00:00

abstract：INTRODUCTION:Autosomal dominant haploinsufficiency of GATA2 causes monocytopenia and natural killer cell lymphopenia, resulting in predisposition to mycobacterial, fungal, and viral infections. METHODS:Herein we report on the clinical, serologic, electrophysiologic, and pathologic evaluations of a 29-year-old woman wi...

journal_title：Muscle & nerve

authors： Kazamel M,Klein CJ,Benarroch EE,Patnaik MM,Tracy JA

更新日期：2018-01-01 00:00:00

abstract：:New developments in the rapid diagnosis and treatment of boys with Duchenne muscular dystrophy (DMD) have led to growing enthusiasm for instituting DMD newborn screening (NBS) in the United States. Our group has been interested in developing clinical guidance to be implemented consistently in specialty care clinics ch...

journal_title：Muscle & nerve

authors： Kwon JM,Abdel-Hamid HZ,Al-Zaidy SA,Mendell JR,Kennedy A,Kinnett K,Cwik VA,Street N,Bolen J,Day JW,Connolly AM

更新日期：2016-08-01 00:00:00

abstract：:The connective tissue diseases, such as rheumatoid arthritis, Sjögren's syndrome, systemic lupus erythematosus, systemic sclerosis, and vasculitis, may cause various disorders of the peripheral nervous system. In this review, the clinical effects of the connective tissues diseases on nerve and muscle are examined with...

journal_title：Muscle & nerve

authors： Rosenbaum R

更新日期：2001-02-01 00:00:00

abstract：INTRODUCTION:Amyloidosis derived from transthyretin (TTR) molecules is typically caused by mutations of the TTR gene. METHODS:We describe an elderly patient with a severe length-dependent polyneuropathy that unexpectedly proved to be caused by wild-type transthyretin amyloidosis. RESULTS:The diagnosis was made by mus...

journal_title：Muscle & nerve

authors： Lam L,Margeta M,Layzer R

更新日期：2015-07-01 00:00:00